Nattokinase is a soybean food content. It is a 275 amino acid peptide. It is said to have similar clot-dissolving abilities as does plasmin, an enzyme that we all have in our blood as our natural defense mechanism to dissolve unwanted blood clots. The "clot busters" used in clinical medicine (tPA=tissue plasminogen activator, streptokinase, urokinase, etc) to dissolve blood clots that have led to heart attacks, strokes, pulmonary embolism or deep vein thrombosis, all work through enhancing plasmin's action. They have to be given intravenously, because they are not active when given orally.
Nattokinase increases the clot dissolving activities (= fibrinolytic activity) of blood in animals and human volunteers and that it suppresses clot formation and enhances clot resolution in animals. However, to my knowledge, only one clinical study has been performed to assess whether Nattokinase has any real benefit in the prevention of blood clots in humans. In that study (reference 7) Nattokinase or placebo were given to individuals prior to long distance (7-8 hours) flights. Of the 92 individuals in the placebo group 7 developed a clot, all without symptoms, discovered by ultrasound; of the 94 individuals in the Nattokinase group none developed a clot. Main flaw of the study, limiting the usefulness of its conclusions, is, that the publication does not indicate whether this was a double-blinded study, or, at least, an investigator-blinded study. A non-blinded study has the potential for bias, limiting the validity of its findings and conclusions.
Nattokinase NSK - SD, 100 mg
Nattokinase Supplement Facts
Serving Size 1 Capsule
Amount Per Serving: % Daily Value
Nattokinase ( NSK - SD*) providing 2,000 fibrin units ( FU ) of activity 100 mg *
Suggested Use: 1 capsule nattokinase 1 or two times daily on an empty stomach with 8 ounces of water, or as recommended by your health care professional.
* Nattokinase daily value not established.
Other Ingredients: microcrystalline cellulose and gelatin (capsule).
Contains no yeast, dairy, egg, gluten or wheat. Contains no sugar, salt, preservatives, or artificial color, flavor or fragrance. Contains Soy.
Warnings: Do not use nattokinase if you have blood coagulation or blood pressure disorder. Consult your healthcare professional before taking this product if you are taking any drug that effects blood coagulation or blood pressure such as prescription vitamin K, heparin, warfarin (Coumadin), diuretics, ACE inhibitors, or beta blockers, or if you are pregnant or breastfeeding.
"I started 25 patients on nattokinase last week in our clinic and patients are reporting that they have more energy,less pain and a clearing of mental confusion in the first few days of use! We have already added nattokinase into our medical protocol for detoxification of neurotoxins."
The literature about natto and nattokinase is very impressive. The first patient we asked to try it had a rapid and dramatic response. While this was likely an unusually good result, nattokinase appears to be a true therapeutic breakthrough."
"Because of our deep involvement in the nutrition field, my husband and I are aware of a long list of helpful, natural, and safe modalities for recovery from illness - regardless of the disease category. Many of these substances worked well for my husband's recent problem, but nothing appeared as magical as nattokinase! In terms of his energy and well-being, it was as though a switch was suddenly turned on when he started taking this amazing supplement.The positive effects of nattokinase are swift and dramatic!"
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