The school was established at the time when the Ministry of Education in Ghana had conceived the idea of de-boardenising schools to alleviate the problems of high boarding fees and to increase the intake of day students. It was also in response to meet the increasing demands for vacancies in secondary schools in the Tema Township, in the Greater Accra Region of Ghana, hence the conversion of the Community 4 No.2 Middle School into a model day secondary school known as Chemu Secondary School with the motto: 'Discipline and Hardwork'. The school was formally opened on the 12th of October 1982 with a double stream of 86 students.

The school offers the following programmes: Science; General Arts; Visual Art; Home Economics; and Technical. The school from its humble beginnings rose up to fame within a short period and chalked very impressive successes in the academic field, sports and other related fields rubbing shoulders with very old and endowed school. Some examples of the few achievements and progress made in these fields include the high percentage passes recorded and recent history made by placing 3rd in the National Science and Mathematics Quiz at the first entry in 2001. The school also won the Best Teacher Award, Tema District, secondary school level for the years 1996 and 1999. The school won the 3rd position at the Regional level in 1995 and 1st position at the Regional level in 2002. In other areas like Sports the school has produced great athletes and footballers that include Dan Addo and Attakora Amaniampong who were among the cup-winning Black Starlets squad of 1991 and 1995 respectively. Monica Twum, an athlete of the Olympic game squad. These is but a few of the numerous strides made by the school.