Rocket Launcher w/ infinite ammo
To claim the Rocket Launcher with infinite ammo, you must complete the game in under 3 hours. After the credits roll through, you will see a rocket fly past the screen. Save the game on your memory card and then restart the game from your saved file. You will now be able to play through the entire game using the Rocket Launcher with infinite ammo.

Special Key and New Clothes
To unlock the closet in the room with the large mirror, you must get the Special Key. To do this, you must complete the game rescuing both of your colleagues. So if you are playing as Jill, you must rescue Chris and Barry. If you are playing as Chris, you must rescue Rebecca and Jill. Once the credits roll through, a screen will appear telling you you’ve been awarded the Special Key. Now save the file to your memory card and then restart the game from your saved file. When you restart the game, you will have the key in your inventory.

Mixing the V-Jolt
Enter the room with the number pad in the dormitory. To create the V-Jolt, mix UMB No. 2 with water to create the No. 3 chemical. Then mix UMB No. 2 with UMB No. 4 to create Yellow-06. Then mix No. 3 with UMB No. 4 to create No. 7. Next mix Yellow-06 with No. 7 to get No. 13. Finally make more No. 3 and then mix it to No. 13 to make V-Jolt.

Play slightly easier game as Jill
Start a new game as Jill. After Barry and you enter the dining room, return to the main hall. Wesker will tell you to investigate the gun shots. The game will return to the dining room. Turn back around and try to go back out the doors. Barry will say "Lost Courage already? That's not like you." Move to the blood stain and look at it. Barry will saythe usual. Then, go over to the grandfather clock. As soon as you do this, a zombie will come out the door. Barry will kill it. Return to the main hall and get the lockpick. Now, go back to the room where Kenneth was being eaten. He has no clips and his legs are now missing. The game will supposedly be easier now.

Claiming the Eagle/Wolf Medals
To find the Eagle and Wolf medals, you must first find both of the Doom Books. Once you have both of them in your possession, examine the books and turn them on their side with the pages facing you. Press X to open the books and retrieve their emblems.