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. RYR1 (Ryanodine Receptor for skeletal muscle) ryanodine receptor: a Ca2+ release channel a very large protein 4 homoteric subunits each subunit has 5,035 amino acids and weighs 565 kDa total weight around 2,200 kDa Home. . .Intro. . .Location and Function. . .Mutations. . .MH. . .Summary