Thomas Dye is the cartoonist who creates Newshounds. Newshounds has anthropomorphic (animals that are attributed human-like qualities) elements mixed in with human society in a weekday serial strip that follows the lives of the employees of the all-animal news station, KPET. KEPT and the animals are owned by Lorna Dilbrook and the operations are ultimately run by her. Despite that, the staff of KEPT keeps her on her toes, from problems such as mind control of the pet population, to her father trying to get money from her to pay off his gambling debts.

Jason Sigala and Seth Weisgarber are the cartoonists who creates Niego. Niego is a serial strip that follows the lives of three friends: John, Leland, and Libby. Several years ago, John lost his family to a electrical fire over the Christmas holidays, and he was the only one to survive by leaping out of a second story window. This traumatic event obviously still haunts him since he now lives every moment to the fullest, frankly giving his opinions about anything, not really caring about the repercussions of his actions. He received a large inheritance (probably due to life and fire insurance) and was able to buy a two-story house to live in so he could have a place to stay. Leland, seeing his friend taking things pretty hard, moved in with him, and helped him through that difficult period of his life. Leland is the type of person to do that for his friends, but when it comes to strangers, people in general piss him off, and he lets them know it. Leland is an second grade elementary school teacher despite the fact that he hates children with a passion, but he only took the job because it was the only job he could get with his English degree. Sometimes his life gets so stressful that he thinks he hallucinates talking with Val Kilmer dressed up as Doc Holiday, but may or may not be wrong in thinking that Val is just a hallucination. Libby is a waitress at the local diner, where she met John when he made an unsuccessful attempt to pick her up, but followed him home as he seemed an interesting person, and has hung out with them ever since.

Mitch Clem is the cartoonist who creates Nothing Nice to Say. Nothing Nice to Say is a comic in the gag-a-day format (having no overall storyline, but maintains the cast of characters) that follows the lives of two roommates, Blake and Fletcher. Blake prefers to be seen as an intellectual on various aspects of punk culture. He is the more reserved of the two, preferring to sit back and watch events unfold. Fletcher, on the other hand, is very impulsive and will say about anything that is on his mind. He tries to control some of his natural tendencies when around female waitresses or baristas that he likes, but generally to no avail. The two spend their free time hanging out with friends at bars, or going to various live shows. They even tried to start their own punk band called The Negative Adjectives, and managed to secure their mutual friend, an anthropomorphic (animals that are attributed human-like qualities) gopher named Cecil, to play bass, but he quit the band before their first show. Even still, Blake and Fletcher continue working with the band, occasionally playing shows in various clubs, but don't pursue it as their main focus. Generally Blake and Fletcher enjoy having lengthy discussions about the state of punk rock, and usually end up complaining about various aspects or insulting bands that have deviated from the punk rock image, have no talent, or "sold out".

Darren "Gav" Bleuel is the cartoonist that creates Nukees. Nukees is a serial strip that follows the life of a Nuclear Engineering student (aka a Nukee) named Gav. Gav is your average ten-year grad student, who happens to live on campus in his office while he “works” on his thesis. In reality, he works on anything but his thesis, preferring to spend his time on his inventions. He prefers this arrangement since as a grad student, he has access to all of the labs on campus, and allows him to create things from a giant, nuclear-powered, robot ant, to a mechanized lawyer-bot of destruction, to even a sentient virtual pet gone power-mad.

Michael lalonde is the cartoonist who creates Orneryboy. Orneryboy is a serial strip that follows the lives of a unusual couple. Orneryboy is a moody guy who dresses like a goth, but spends a lot of his time hating random things that piss him off. He usually vents his anger verbally, but when some people prove to be a little thickheaded, more radical methods are brought to bear. This is because of his bleak outlook on life and humanity. Fortunately, he does have one shining spot in his life, his lover, Dirtygirl. Dirtygirl, much like the name implies, can be messy and disorganized, but she has a passionate love for life that can, at times, baffle Orneryboy. She defends life, all life, and as such is a strict vegetarian, going so far as to bury the bones that are left over from a chicken dinner that Orneryboy had. Recently, her beliefs have caused her to defend the life of Brian, a zombie that crawled his way out of the ground in her garden. Unlike most brain-eating zombies, Brian doesn't hurt Dirtygirl, but treats her with respect and love. Orneryboy at first protested the idea of a brain-eating corpse living in the basement, but he was no match for Dirtygirl's persuasive hold over him. Now the question remains, how long can Brian hold off from trying to eat his adoptive family?

David Craig Simpson is the cartoonist who creates Ozy and Millie. Ozy and Millie is an anthropomorphic (animals who take on human-like qualities), serial strip that follows the lives of two best friends, an artic fox named Ozy and a fox named Millie. Ozy is introspective, submissive, and philosophical about life in general. This is probably because of his unusual family structure, having been adopted at an early age by a red dragon named Llewellyn, whom has been his father figure ever since. The differences between Ozy and Millie are like night and day, where Ozy is passive and serene, Millie is active and rambunctious. This tends to get Ozy dragged into various tangents that Millie finds herself on. Millie constantly questions the social order, and continues to operate outside of the norm, which is fine with Ozy, since his background firmly puts him there. It's obvious where Millie gets her streak of rambunctiousness when you look at what her mom used to be like before society started wearing her down, and the fact that her father is a pirate captain. Where Ozy and Millie tend to go against society's norms, some of their friends (or more at times, acquaintances) firmly stick with their places in the social order. Avery, a raccoon, is an advertisers dream, as he follows all of the constant ads and looks at famous figures for cues on what is cool. Stephan, an aardvark, became disillusioned with the crash of the dotcoms but still struggles to show that being a techno-savant will firmly establish his popularity and financial security. Felicia, a sheep, is a typical “popular” girl, taking her cues from pop-culture, fashion, and famous individuals, she travels with her clique around the school and makes fun of those on the outside of the class social order.

Stephan Pastis is the cartoonist who creates Pearls Before Swine. Pearls Before Swine is an anthropomorphic (animals who take on human-like qualities), daily serial strip that follows the lives of two best friends: a rat named Rat and a pig named Pig. Rat is very enterprising, being ever on the look out for ways to get rich, meet women, and acquire fame. He feels himself as sort of an intellectual, but also feels that his plans and ideas are wasted on his friend Pig. Pig is pretty naïve, and a little slow witted, but he is quite happy with his current lot in life. Rat will get infuriated with Pig's little questions and his games with various people and objects, like his fruit club. So Rat tends to spend more and more time showing he is above those games and showing that he is better than Pig.

Mike "Gabe" Krahulik and Jerry "Tycho" Holkins are the cartoonists who create Penny Arcade. Penny Arcade is a comic in the gag-a-day format (having no overall storyline, but maintains the cast of characters) that follows the lives of two friends, Johnathan Gabriel and Tycho Brahe. Gabe is heavily into video games, and is very competitive over playing the game itself and his extensive knowledge of video games. Gabe has difficulty in controlling his impulses and can suddenly display violent outbursts when he is deprived of his precious gaming. Tycho, on the other hand, is usually the levelheaded one, and tries to keep Gabe in check, if only for his own sanity. Of course, sometimes Gabe goes over the line, and Tycho displays some of his own repressed anger that lurks beneath the surface. Gabe married Kara, who due to Gabe's influence became a gamer as well, but not to the extent that Gabe takes things. Kara usually has to be the voice of reason and remain grounded in reality, lest Gabe spiral out of control. Tycho has been married to his wife Brenna for longer than Gabe has, but Brenna doesn't really get into the games at all. Brenna prefers to do more social interaction and hang out with Kara, than spend her whole day cooped up inside playing video games. Charles (or Chuck as Gabe and Tycho call him) is the self-proclaimed Macintosh guru, who Gabe and Tycho abhor due to his elitist attitude towards PC computers, and their love for PC gaming. Charles re-styled his wardrobe and outward personality when the Macintosh operating system upgraded to Mac OS X, and now sports a sleek new look, but with a more mature nature. At times Gabe and Tycho have problems with objects gaining sentience and becoming anthropomorphic (inanimate objects that are attributed human-like qualities), such as Div (an anthropomorphic DIVX player) or Fruit Fucker 2000 (an anthropomorphic juicer), which frequently enter their home without their knowledge.

Scott Kurtz is the cartoonist who creates PvP: Player vs Player. PvP is a daily serial comic strip that follows the lives of the staff of PvP magazine. The PvP staff is as follows: Cole Richards, the owner and administrative head of PvP; Brent Sienna PvP's creative director; Jade Fontaine, a staff writer who writes about women's point of view toward the video game industry; Francis Ottoman, a staff writer who knows all there is to know about gaming; Robbie and Jase, two “sports writers” who critique sports games, but end up doing more playing than working; and finally, a large blue troll named Skull who has become PvP's unofficial mascot. PvP deals with topics from the gaming industry to relationships by using intellectual humor mixed in with slapstick.

Chris Morrison is the cartoonist who creates The Polymer City Chronicles (PCC). PCC used to be a strip in the gag-a-day format (having no ongoing storyline, but keeping the same characters for the strip) that typically was about gaming or sight gags, but has recently switched to a serial strip. PCC is set in the modern era, in the fictional city of Polymer City. PCC's switch to a serial format is in part to more develop the characters involved, and also to follow some story arcs that Chris Morrison has. PCC follows the lives of the members of OBSESS (the Otto Bonn Society of Extraterrestrial and Supernatural Studies). The members are as follows: Dr Otto Bonn, a former PCU (Polymer City University) professor of theoretical physics; Andrah, an azure skinned alien, with Amazonian physique, who is the wife of Dr Otto; Sheeri, a member of the Anime Exchange Program and also an alien who is a guardian of a special super-technological crystal shard. The group drives around the world in a large RV codenamed HARV (Heavily Armed Research Vehicle). The group has to deal with Dr Otto's wacky experiments, and the being known as Mistress Laura, Flint, and Locke. Mistress Laura, Flint, and Locke were an exotic dancer in her former life, but she was run over by Dr Otto one night. She came back from the dead as one of the undead and is the source of all the problems that the city might experience.

Josh Mirman is the cartoonist who creates Punks and Nerds. Punks and Nerds is a comic in the gag-a-day format (having no overall storyline, but maintains the cast of characters) that follows the lives of two cousins, Brad and Mike. Both Brand and Mike are aspiring artists who are heavily into the punk culture. Mike is very impulsive and open about his wants or desire, and this is due to his growing belief that he has a power to make wishes come true, but doesn't use it often. He spends a lot of his time trying to relive elements that he enjoyed from his childhood, such as playing on his Nintendo game console, but doesn't let his desire try to make him constantly chase after the past. Brad is shy when it comes to taboo subjects (such as talking frankly about sex), and gets embarrassed easily when talking with Mike or his longtime friend Jade, who he has become romantically involved with (notably after Mike granted Brad's wish for it to happen). Jade works in a comic book store for the benefits, but dislikes the typical customers that frequent the store. Mike and Brad consider Jade to be one of the "guys" as she can usually talk circles around them both, but also has a philosophical side that she shares only when she feels overwhelmed with life. Jade also spends a lot of her time with Sara, who used to be Caucasian before Mike made a wish that she was an Asian, so he could have more friends of different minorities. Sara is very much into computers and technical things, but keeps it hidden from people lest they make fun of her. Sara is dating the local superhero vigilante named Bruceman, who travels around with Brucelad, solving crime and helping people out, and all while wearing underwear on his head.

Jeph Jacques is the cartoonist who creates Questionable Content. Questionable Content is a serial strip that follows the life of a music aficionado named Marten Reed. Martin is very educated when it comes to music, but he has difficulty opening up to strong women unless he is able to relax around them. Martin's timidity towards women and attraction to strong females is partially due to the fact that his mother is Veronica Vance, a famous S&M dominatrix who stared in many erotic videos. That's not to say that he is interested in his mother that way, but it did have a formative impression on him since he knew what she did for a living ever since he was a child, and thought it was a normal thing. He works in an office complex, as a office assistant (of course his business cards call him "office bitch", but his boss is just being playful), but it's a job he really doesn't like. Fortunately, he met a girl named Faye Whitaker, who he falls for. Originally from the southern United States, Faye moved north to escape from some problems in her past, which keep her on the defensive most of the time. Due to a fire at her apartment complex, she moved in with Martin and quickly established a strong friendship with Martin, but because of her past, she doesn't take the friendship any further. Faye works at a coffee shop where her boss, Dora Bianchi, allows her to vent any anger or frustration she might have on the customers, in order to keep up the ideal of aloof coffeehouse baristas. Dora immediately showed an interest in Martin (much to the secret annoyance of Faye), but has to wait for Martin to sort out his feelings for Faye, which leaves her waiting until Faye can sort through her past troubles in order to see if she has real feelings for Martin.

Greg Dean is the cartoonist who creates Real Life. Real life is set in modern times in the United States. Real Life is a weekday serial strip that follows the lives of seven friends in their psuedo-real life situations. Real Life usually deals with game playing, fighting evil computer versions of them, or just having fun. The cast is as follows: Greg, the cartoonist, creator of the world, he doles out rewards or punishments to the characters that he has made. Usually he is only seen as a disembodied voice; Greg (the character) a fantasy gamer and sword ends up being the one the cartoonist favors (we all wonder why right? :) ) yet, ends up being the one who gets into the most trouble; Dave is a quake-loving gamer who spends most of his time honing his skills in first person shooters, and working to create the best computer system around; Crystal is Greg's (the cartoon version) girlfriend, but is not to be dismissed lightly, since she is as big of a gamer as the rest of them; Tony is a gamer like the rest, but unlike the rest, he takes old systems and makes fantastic things out of them.

A cartoonist nicknamed Eight created Road Waffles. Road Waffles was a serial strip that followed the life of a trigger-happy young woman named Haley. After stealing her ex-boyfriend's car and leaving town, she would drift from town to town seeking something to make her life more exciting. One thing that she found to make her life more exciting was to hold up gas stations. One day she held up a gas station that Bruno worked at. When she held him up, he ended up going with her, leaving his gas-pumping life behind. They had many adventures on the road, ranging from fighting a psychopathic gun-toting squirrel, to running into a serial killer with a fetish for pigs, to even a kid-turned-zombie and his horde of zombie road kill.

Clay & Hampton Yount are the cartoonists who create Rob and Elliot. Rob and Elliot is a serial strip that follows the lives of two apartment roommates, for whom the comic is named after, Rob and Elliot. After college, Rob entered the "lucrative" career of selling his various bodily fluids to whoever will buy them, and Elliot earned a teaching degree and teaches "English as a Second Language" at the local college. Of the two, Rob is the more impulsive one, almost immediately saying or doing things right after he thinks of them, no matter what the consequences may be. For some reason, Rob undeniably attracts strange and unusual occurrences to him, just as a magnet attracts iron filings to it, which is probably the cause of his impulsive nature. These frequently strange occurrences tend to stress Elliot out, as he is the more grounded of the two, and worries about the consequences on his career and life. This does cause some stress between the two, as Elliot frequently feels like he is the only adult living in the apartment, and wishes Rob would take things a little bit more seriously and take on more responsibilities. Of course, Rob doesn't plan on doing anything more than he has to, and prefers to spend his time planning out strange and intricate plans, as the whim to do so takes him. This doesn't mean that the two are incompatible, since they share a lot of the same interests and have a similar sense of humor.

Reinder Dijkhuis is the cartoonist who creates Rogues of Clwyd-Rhan. Rogues of Clwyd-Rhan is a weekday serial strip that is the story of a thieving band of the same name that operate in Clwyd-Rhan. Rogues of Clwyd-Rhan is set in a medieval European setting, but is a fantasy comic. The band is led by Ragnarok "Pulp" Torvaldsen, and comprises the following members: Kel Mansdóttir a half-faerie witch; Jodoque Davignon a bard; Tamlin LLamfarythich, former leader of the gang and fierce thief berserker, now a drunk; Atra Cambrensis a slightly addle-minded witch; and Jake the Gnome, a fighter who speaks rarely save to make a smart mouthed comment. As the name suggests the thieving band primarily steals for a living, but sometimes does a job for people who can pay the right price. Most of the time that price has to include a large amount of beer or ale in order for the Rogues to be interested in the job.

Dan Canaan is the cartoonist who creates Roomies: Crimes Against Nature. Roomies: Crimes Against Nature is an anthropomorphic (animals that are attributed human-like qualities), serial strip that follows the life of two roommates, a pony named Flinthoof and a tiger named Tibo. Flinthoof is a computer tech who has a severe addiction to any kind of mint. Tibo, a green and orange striped tiger (think Cringer from He-man), is a computer programmer. Their lives are peaceful for the most part, aside from "little things" ranging from their computer calling itself Borg and trying to take over the house, to Flinthoof's pet ferrets converting their cage into a car then proceeding to attempt to take over the world, to even going into cyberspace to bring back the ferrets.

Sam Logan is the cartoonist who creates Sam and Fuzzy. Sam and Fuzzy is a serial strip that follows the life of two roommates. Sam is a struggling 24-year-old bookstore clerk at Burton's Books, while he tries to make up enough money for wrecking a taxi at his former job. Sam has no idea what he wants most of the time, let alone what sort of goal he is working towards. Sam tries to put up a brave front, bragging to his friends about his life so that they don't really know how unhappy he is, but Sam isn't that good of a liar. All throughout his life, Sam has been plagued by insecurities and doubts, a fact that allows him to be easily manipulated by others (such as Fuzzy). Fuzzy, an anthropomorphic (animals that are attributed human-like qualities) bear, who frequently causes Sam no end of trouble. Fuzzy is extremely impulsive and says whatever is on his mind, and most of which is not all that pleasant. Fuzzy has some psychological issues, but despite his aggressive and psychotic behavior, he really does care about Sam, even if it's because Sam is his favorite little toy. Fortunately for Sam, his coworker and former girlfriend, Alexa, tries to help Sam along. This is partially because she can see some of her own insecurities mirrored in him and partially due to her unresolved feelings towards him. The reason for their initial breakup is mostly due to Sam's resentment towards her attempts at helping him, as she did not realize that he does not truly want to fix his problems at the moment. Sam is usually blinded to the fact that others try to help him out, and casually dismisses their advice. For now, Sam is content to amble through life, wallowing in self-pity at his situation, but unwilling to try and change things, as all change is usually accompanied by some risk.

John Allison is the cartoonist who creates Scary-Go-Round. Scary-Go-Round is a spin-off serial strip from the comic, Bobbins, that follows the lives of several former employees of the now defunct magazine, City Limit. Tim Jones is the current mayor of Tackleford who is an inventor of many strange, but occasionally useful inventions. A lot of Tim's work crosses over to mad science, but he tends to be kept in check from crossing over to evil mad science by his friends and lovers. Fallon Young is a former secret agent, who was not very good at completing all aspects of her job in a quiet manner, but generally got the job done. Her life tends to be far more action-packed than those of her friends, and she ends up spending a lot of her time off in other countries. Ryan Beckwith enjoys life as a professional slacker, a trait that rubbed off on him some from his father, who was grooming him to become "the king of the tramps" and live a hobo's life. Having turned his back on his father's wishes, Ryan spends a lot of time with his friends, as he struggles to find meaning in his life. Shelly Winters was the former mayor's secretary, and due to his peculiar nature and various neurosis, Shelly was able to run the whole city with an iron fist. This posed a problem if and when she got drunk, as a lot of her pent up aggression would come streaming forth, and cause embarrassments in public. In recent years, Shelly has had a number of brushes with death, and successfully faced her greatest fear in order to be able to return to the land of the living. Amy Chilton is the daughter of Len Pickering, the former editor and owner of City Limit. Amy was not spared any expense as she was growing up, as her father could never really say no to his little girl, and as such, she grew up a little spoiled. She was the former assistant to Tim in his workshop, but due to an attempted theft of his time-traveling teapot, she was dismissed of that position.

David Willis is the cartoonist who creates Shortpacked!. Shortpacked! Is a serial strip that follows the lives of the employees of a individual retail toy outlet called Shortpacked!. Galasso, the store manager, has delusions of grandeur, and treats his managerial experience at Shortpacked! as one step in his master plan of taking over the world. As such, he views his employees as his own minions, and expects nothing but the very best in results and loyalty to him and his mission. One of Galasso's favorite employees, Ethan, on the other hand, humors his boss's quirks and rants, because it has been his dream to work in a toy store since he was little. Ethan tries his best to keep his job but not to undermine his underlying values, but is not always successful. Despite any lapses, he loves toys, and he makes sure that each and every customer feels happy with their purchases, because the remembers the feelings he had upon receiving toys when he was a kid. Robin is a newly hired employee, but in her short time at the store, she has proven herself to be a swift worker, rivaling Ethan for Galasso's approval. Whimsical and subject to flights of fancy, Robin was formerly employed by a secret government organization(see It's Walky), and she took the job at Shortpacked! simply because it interested her. She has taken to befriending her fellow employee, Amber, as she noticed Amber's tendency towards being shy and introverted, and hopes to one day bring Amber out of her shell. Robin was surprised to see Mike also working in the store, as he used to work at the government facility with her, but was never really friendly with people. Mike enjoys working as a customer service representative, as it allows him to screw over and berate the customers on a daily basis. The last employee, Rick, spends most of his time practicing to be a ninja, and always tries to sell ninja merchandise to any customer, no matter what they came to the store for originally.