When first posted as such in January 1964, SR 522 began in Downtown Seattle and headed north via Fairview Ave and Eastlake Ave to the University Bridge. On the north side of the bridge, SR 522 split into two one way streets and headed north to Bothell Way (now Lake City Way inside the City of Seattle). SR 522 followed Bothell Way through Lake City, Lake Forest Park, and Kenmore to Bothell. From Bothell, SR 522 headed east to Woodinville, then south to Redmond. In Redmond, SR 522 turned left and went east via Fall City and Snoqualmie to Jct US 10 in North Bend, where SR 522 ended
When I-5 opened from Downtown Seattle to Everett in the mid 1960s, Bothell Way (Lake City Way) was extended west from Roosevelt Way NE to I-5. SR 522 from Downtown Seattle to Bothell Way was dropped from the state highway system. The I-5/Bothell Way interchange became the new western terminus of SR 522.
In 1970, SR 522 from Woodinville to North Bend was renumbered SR 202. Former SR 202 from Woodinville to Jct US 2 in Monroe became part of SR 522. Today, SR 522 from I-5 Exit 171 in Seattle to Jct US 2 in Monroe is 24.68 miles long.
Before 1964, SR 522 from Seattle via Bothell to North Bend had been the Bothell branch of PSH 2.
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