The Second International
Conference on the
Neuroendocrine Immune Basis of the Rheumatic Diseases
Grand Hotel Miramare, Santa Margherita Ligure
Genova * Italy, September 21st-23rd, 2001
Friday September 21st,2001
Afternoon 1 .00 - 7.30 p
10.00 - 12.00 am Registration/Brunch
1.00 pm Presentation of the Conference
CHAIRMAN G Chrousos - G Neeck
1.30 - 3.30pm LECTURES
1.30 pm TEN YEARS OF NEUROIMMUNOENDOCRINOLOGY
OF THE RHEUMATIC DISEASES. WHERE WE WERE, WHERE WE ARE, AND WHERE WE ARE GOING
Wilder R L.
MedImmune, Gaithersburg, MD, USA.
2.00 pm THE ADRENAL HORMONE METABOLISM IN THE IMMUNE/INFLAMMATORY REACTION
Bornstein S R.
Dept of Endocrinology, University of Düsseldorf, Germany.
2.30 pm PERSPECTIVES ON ADRENAL STEROID RELATIONSHIPS TO RHEUMATOID
ARTHRITIS
Masi A T, Chatterton R T, Aldag J C, Malamet R L.
University of Illinois College of Medicine at Peoria, Peoria and Chicago,
IL, and Hagerstown, MD, USA.
3.00 pm NEURAL-IMMUNE INTERACTIONS IN HEALTH AND DISEASE
Sternberg E M.
The University of Texas Sothwestern Medical Center. Dallas, USA.
CHAIRMAN J W J Bijlsma - A T Masi
3.30 - 4.00 pm Coffee Break and poster viewing
session
38. NOREPINEPHRINE FROM SYNOVIAL TYROSINE HYDROXYLASE AND CD163 POSITIVE
MACROPHAGES IS A STRONG INDICATOR OF SYNOVIAL INFLAMMATION IN RHEUMATOID
ARTHRITIS
Miller L E, Grifka J1, Schölmerich J, Straub R H.
Dept Internal Medicine & 1Orthop. Surgery, University Hospital Regensburg,
Germany.
22. STRESS AFFECTS SERUM PROLACTINE LEVELS IN PATIENTS WITH SYSTEMIC
LUPUS ERYTHEMATOSUS
Dostàl C, Marek J1, Moszkorzovà L, Lacinovà Z1, Musilovà
L.
Institute of Rheumatology, 13rd Med dept 1st Med Fac Charles University,
Prague, Czech Republic.
26 FATIGUE DURING THE DAY IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
AND PRIMARY SJÖGREN’SSYNDROME
Hartkamp A1, Godaert GLR2, Greenen R2, Garssen A2, Kruize AA1, Bijlsma
JWJ1, Derksen RHWM1.
1Depts of Rheumatology and Clinical Immunology, UMC Utrecht and 2Health
Psychology, Utrecht University, Utrecht, The Netherlands.
35. CORTICOTROPIN RELEASING HORMONE: A PATHOBIOLOGICAL ROLE IN HUMAN INFLAMMATORY
ARTHRITIS
McEvoy AN, Bresnihan B, Fitzgerald O, Murphy E P.
Dept of Rheumatology, St. Vincent’s University Hospital, Dublin,
Ireland.
40. BRAIN FUNCTIONAL INVOLVEMENT BY PERFUSION SPECT IN SYSTEMIC SCLEROSIS
AND BEHÇET DISEASE
Nobili F, 1Cutolo M, 1Sulli A, Vitali P, Rodriguez G.
Clinical Neurophysiology and 1Rheumatology Divisions, DIMI, University
of Genova, Italy.
42. ANOMALIES OF HYPOTHALAMO-PITUITARY-ADRENAL AXIS IN CHILDREN WITH
OLIGOARTICULAR ONSETIDIOPATHIC ARTHRITIS
Picco P, Gattorno M, 1Vignola S, Loy A, 1Sormani MP, Buoncompagni A.
Dept of Rheumatology and 1Dept of Gastroenterology, G.Gaslini, Institute
for Children, and Institute for Cancer Research, Genova, Italy.
50. DIFFERENT EFFECTS OF STRESS OF CHRONIC FOOD RESTRICTION AND CHRONIC
PSYCHOLOGICAL CHALLENGE ON THE DEVELOPMENT OF ADJUVANT ARTHRITIS IN MALE
LONG EVANS RATS
Seres J, Stancikovà M 1, Svik K 1, Krsovà D, Jurcovicovà
J.
Dept of Normal, Pathological and Clinical Physiology, Third Medical Faculty
Charles’ University, Prague, Czech Republic and 1Research Institute
of Rheumatic Diseases, Piest’any, Slovakia.
70. PROLACTIN/CORTISOL RATIO IN RHEUMATOID ARTHRITIS
Zoli A, Lizzio MM, Barini A1, Scuderi F2, Altomonte L, Mirone L, Magarò
M.
Istituto di Medicina Interna e Geriatria, 1Istituto di Chimica Biologica,
2Istituto di Patologia Generale, Università Cattolica del Sacro Cuore,
Rome, Italy.
CHAIRMAN J M Dayer - S Bornstein
4.00-6.00 pm LECTURES
4.00 pm THE ANTI-INFLAMMATORY EFFECT OF CYTOKINES
Dayer JM.
Division of Immunology and Allergy, Dept of Internal Medicine, Hôpitaux
Universitaire de Géneve, Géneve, Switzerland.
4.30 pm INTERACTIONS BETWEEN GLUCOCORTICOIDS AND CYTOKINES IN BONE
MICROENVIRONMENT
Angeli A, Dovio A, Sartori ML, Masera RG, Ceoloni B, Prolo P1, Racca S,
Chiappelli F1. Dept of Clinical and Biological Sciences, University of Turin,
Italy. 1Laboratory of Oral and Molecular Immunology, UCLA School of
Dentistry, Los Angeles, USA
5.00 pm CYTOKINES AND HORMONES AS POSSIBLE LINKS BETWEEN ENDOCRINOSENESCENCE
ANDIMMUNOSENESCENCE
Straub R H, Zietz B, Schölmerich J.
Dept of Internal Medicine I, Laboratory of Neuroendocrinoimmunology, University
Medical Center, Regensburg, Germany.
5.30 pm REGULATION OF LEUKOCYTE ENDOTHELIAL CELL INTERACTION BY GLUCOCORTICOIDS
Pitzalis C.
Rheumatology Unit, Thomas Guy House. Guy’s Hospital, London, UK.
CHAIRMAN J W J Bijlsma - J A Da Silva
6.00 - 6.30 pm Coffee Break and poster
viewing session
57. UNCOUPLING OF THE SYMPATHETIC NERVOUS SYSTEM AND THE HYPOTHALAMIC-PITUITARY-ADRENAL
AXIS IN INFLAMMATORY BOWEL DISEASE
Straub R H, Herfarth H, Falk W, Schölmerich J, Andus T.
Dept of Internal Medicine, University Hospital, Regensburg, Germany.
61. MELATONIN PARTECIPATES IN THE CONTROL OF TESTOSTERONE SECRETION FROM
RAT TESTIS: AN OVERVIEW OF OUR EXPERIENCES
Valenti S, Giusti M.
Dipartimento di Scienze Endocrine e Metaboliche, University of Genova,
Italy.
17. MELATONIN SERUM LEVELS IN RHEUMATOID ARTHRITIS
Sulli A, Maestroni GJM1, Pizzorni C, Hertens E1, Craviotto C, Cerchi F,
Villaggio B, Seriolo B, Cutolo M.
Division of Rheumatology, Dept of Internal Medicine, University of Genova,
Italy and 1Istituto Cantonale di Patologia, Center for Experimental Pathology,
Locarno, Switzerland.
63. DECREASED BETA2-RECEPTOR AGONIST INDUCED CELL DEATH IN B LYMPHOCYTES
FROM PATIENTS WITHRHEUMATOID ARTHRITIS
Wahle M 1, Kölker S2, Häntzschel H1, Krause A3, Baerwald C G
O1.
1Dept. of Medicine IV, University Hospital Leipzig; 2University Children’s
Hospital, Heidelberg; 3Dept of Rheumatology and Clinical Immunology, Charité
University Hospital, Berlin, Germany.
67. THE CHANGE IN LEVELS OF JOINT MARKERS IN ARTICULAR CHONDROCALCINOSIS
WITH GONARTHROSIS
Yamaguchi T1, Shiraishi M1, Shirahama S2.
1Dept of Orthopedic Surgery, 2Dept of Internal Medicine, Kamigoto Hospital,
Nagasaki, Japan.
69. DIFFERENTIAL EXPRESSION OF IL-15 AND IL-15 RECEPTOR ISOFORMS
IN SELECT STRUCTURES OF HUMAN FETALBRAIN
Kurowska M1, Rudnicka W1, Maslinska D2, Maslinski W1.
1Dept of Pathophysiology and Immunology, Institute of Rheumatology; 2Dept
of Developmental Neuropathology, Institute-Center of Experimental and Clinical
Medicine, Polish Academy of Sciences, Warsaw, Poland.
71. PROINFLAMMATORY CYTOKINES INHIBIT NEURALLY-MEDIATED LACRIMAL
GLAND SECRETION: IMPLICATIONS FOR AUTOIMMUNE XEROPHTHLAMIA
Zoukhri D, Kublin C L.
Schepens Eye Research Institute, Dept of Ophthalmology, Harvard Medical
School, Boston, USA.
23. GLUCOCORTICOID RECEPTOR AND NFKappaB SUBUNIT P 50 EXPRESSION
IN PATIENTS WITH RHEUMATOID ARTHRITIS
Eggert M1, Klüter A 2, Neeck G2.
1Institute for Genetics, University of Giessen, 2Kerckhoff Clinic, Dept
of Rheumatology, University of Giessen, Bad Nauheim, Germany.
CHAIRMAN A T Masi - A Marmont
6.30-7.30 pm SELECTED ORAL PRESENTATIONS
6.30 pm ESTROGENS AND THE VASCULAR ENDOTHELIUM
Cid M C., Schnaper H W1, Kleinman H K2.
Hospital Clinic, University of Barcelona, IDIBAPS, Spain.
1Northwestern University, Chicago IL; 2NIH, Bethesda, MD, USA.
6.45 pm RELATIONSHIP BETWEEN GLUCOCORTICOIDS AND GONADAL STEROIDS
IN RHEUMATOID ARTHRITIS
Da Silva J A P.
Servico de Medicina III e Reumatologia, Hospitais da Universidad de Coimbra,
Coimbra Codex, Portugal.
7.00 pm A NOVEL ROLE FOR NFkB AND CREB IN MEDIATING CYTOKINE-INDUCED
NURR1 TRANSCRIPTION INRHEUMATOID ARTHRITIS SYNOVIAL TISSUE
McEvoy A, Bresnihan B, Fitzgerald O, Murphy E P.
Dept of Rheumatology, St. Vincent’s University Hospital, Elm Park,
Dublin, Ireland.
7.15 pm NOVEL OPIOID PEPTIDES ENDOMORPHIN (EM)-1 AND EM-2 IN HUMAN AND
RODENT IMMUNE TISSUES
Jessop D S, Harbuz M S.
University Research Centre of Neuroendocrinology, University of Bristol,
Bristol, UK.
8.00 pm DINNER
Saturday September 22nd,
2001
Morning 8.3 am0 - 1 .00 pm
CHAIRMAN E M Sternberg
- G P Crhousos
8.30 - 10.30 am LECTURES
8.30 am ENDOCRINE-IMMUNE-INTERACTIONS
Chrousos G P.
Pediatric Endocrinology Section, DEB, NICHD, NIH, Bethesda, MD, USA.
9.00 am STRESS AND RHEUMATIC DISEASES
Shedlowski M 1, Schmdit R E2, Heijnen C J3.
1Dept of Medical Psychology, Medical Faculty, University of Essen, Germany;
2Dept of Clinical Immunology, Hannover Medical School, Hannover, Germany;
3Dept of Pediatric Immunology, Wilhelmina Children Hospital, Utrecht, The
Netherlands.
9.30 am. NEUROPEPTIDES IN EXPERIMENTAL AND DEGENERATIVE ARTHRITIS
Konttinen Y T.
Institute of Biomedicine, Dept of Anatomy, University of Helsinki, Helsinki,
Finland.
10.00 am MECHANISMS OF PAIN IN ARTHRITIS
Schaible H G.
Department of Physiology, University of Jena, Jena, Germany.
CHAIRMAN A T Masi - D A
Sullivan
10.30- 11.00 am Coffee Break and poster
viewing session
3. EFFECTS OF HORMONE REPLACEMENT THERAPY ON CHRONIC GRAFT-VERSUS
- HOST DISEASE ACTIVITY IN WOMEN TREATED WITH ALLOGENEIC BONE MARROW TRANSPLANTATION
FOR HEMATOLOGIC MALIGNANCIES
Balleari E1, Garrè S1, Van Lint MT2, Spinelli S2, Chiodi S2, Repetto
E1, Massa G1, Bacigalupo A2, Ghio R1.
1Depts of Internal Medicine and 2 Hematology and Oncology, University
of Genova and San Martino Hospital, Genova, Italy.
13. CORTISOL, DEHYDROEPIANDROSTERONE SULFATE AND ANDROSTENEDIONE
LEVELS IN POLYMYALGIARHEUMATICA PATIENTS DURING 12 MONTHS OF GLUCOCORTICOID
THERAPY
Cutolo M, Sulli A, Pizzorni C, Craviotto C, Prete C, 1Foppiani L, 2Salvarani
C, 3Straub RH, Seriolo B.
Div. Rheumatology, Dept Internal Medicine; 1DISEM, University of Genova;
2Rheum Service, S. Maria Nuova H, Reggio Emilia, Italy; 3Dept Internal Medicine,
Regensburg, Germany.
21. AN UNUSUAL CASE OF OSTEOPOROSIS WITH UNDERLYING CONNECTIVE TISSUE
DISEASE
Prasad R, De Silva M.
Dept of Rheumatology, Prince Charles Hospital, South Wales, UK.
25. IDENTIFICATION OF AUTOANTIBODIES IN SERUM OF PSYCHIATRIC PATIENTS ON
FIRST ADMITTANCE AT APSYCHIATRIC UNIT
Favre A1, Grassia L2, Monticelli SM1, Maura E3.
1Centro di Biotecnologie Avanzate-Genova, Italy; 2Servizio di Ematologia,
Ospedale San Martino- Genova, Italy; 3Servizio di Psichiatria (SPDC) ASL
3, Ospedale San Martino- Genova, Italy.
30. SHOULD WE TREAT PREMENOPAUSAL WOMEN SUFFERING FROM SHORT-LASTING
RHEUMATOID ARTHRITIS WITH COMBINATION THERAPY OF DEHYDROEPIANDROSTERONE SULFATE
AND CORTISOL?
Josipovic B, Josipovic A, Micic D.
Institute for Rheumatology and Institute for Endocrinology, Diabetes and
Diseases of Metabolism, Medical Faculty, University of Belgrade, Belgrade,
Yugoslavia.
31. PROLACTIN AND IgG-PROLACTIN COMPLEX LEVELS IN RA PATIENTS
Leiderman S1, Gurfinkiel M1, Damilano S1, Sotelo Lago R A1, Martins S2,
Rosman F2, Hamaui A2, Maccagno A3.
1Division Endocrinologia Hospital Francés; 2Unidad Reumatologia-Hospital
Español; 3Rheumatology, Universidad de Buenos Aires, Buenos Aires,
Argentine.
32. NOREPINEPHRINE INHIBITS ENERGY METABOLISM OF HUMAN PERIPHERAL
BLOOD MONONUCLEAR CELLS VIA ADRENERGIC RECEPTORS
Lünemann J D1, Buttgereit F2, Tripmacher R2, Baerwald C G O3, Burmester
G R2, Krause A2.
1Dept of Neurology, Division of Neuroimmunology, 2Dept of Medicine, Rheumatology
and Clinical Immunology, Charité University Hospital, Berlin, and
3Dept of Rheumatology, University Hospital, Leipzig, Germany.
CHAIRMAN R H Straub
– Y Shoenfeld
11.00-11.30 p.m. LECTURE
11.00 am THE AUTONOMIC NERVOUS SYSTEM AND THE NEURO ENDOCRINE
IMMUNE SYSTEM INTERACTIONS INRHEUMATOID ARTHRITIS
Whale M, Krause A1, Pierer M, Häntzschel H, Baerwald C G O.
Dpt. of Medicine IV, University Hospital Leipzig; 1Dept of Rheumatology
and Clinical Immunology, Charité University Hospital, Berlin, Germany.
11.30- 12.30 am SELECTED ORAL PRESENTATIONS
11.30 am PSYCHONEUROIMMUNOLOGY IN ORAL BIOLOGY AND MEDICINE: THE
MODEL OF ORAL LICHEN PLANUS
Chiappelli F1, Prolo P1,2, Angeli A2, Eversole L R3.
1UCLA Dentistry, 2Università di Torino, 3UOP School of Dentistry,Torino,
Italy.
11.45 am SOMATOSTATIN BLOOD LEVELS AFTER STIMULATION WITH CORTICOTROPIN-RELEASING-HORMONE
INFIBROMYALGIA PATIENTS COMPARED TO HEALTHY CONTROLS
Riedel W1, Netter P2, Leck S3, Neeck G3.
1Max-Planck-Institute, Bad Nauheim; 2Institute for Psychology, University
of Giessen; 3Kerckhoff Clinic, Department of Rheumatology, Bad Nauheim, Germany
12.00 am SEX STEROIDS MILIEU OF RHEUMATOID SYNOVIA
Castagnetta L.
Institute of Oncology, Palermo University Medical School, Experimental
Oncology, Palermo-branch IST, M Ascoli Hospital Cancer Center, ARNAS,
Palermo, Italy
12.15 am PUPILLOMETRY IN SYSTEMIC SCLEROSIS (SSc): A POTENTIAL TOOL
TO EVALUATE IN VIVO THE SP-ERGICFUNCTION?
Del Rosso A1, Bertinotti L1, Pietrini U1, Sicuteri R1, Messori A2, Fanciullacci
M1, Matucci Cerinic M1.
1Dept of Internal Medicine, Section of Rheumatology, Headache, University
of Florence, Italy; 2Drugs Information Center, Azienda Ospedaliera Careggi,
Florence, Italy.
1.00 pm LUNCH
Saturday September 22nd,
2001
Afternoon 3.00 - 7.00 pm
CHAIRMAN R Wilder - J W J Bijlsma
3.00-4.30 pm LECTURES
3.00 pm FIFTHY YEARS OF GLUCOCORTICOIDS: OLD AND NEW ASPECTS
Neeck G.
Kerckhoff Clinic, Dept of Rheumatology, University of Giessen, Bad Nauheim,
Germany.
3.30 pm NONGENOMIC MECHANISM OF GLUCOCORTICOIDS
Buttgereit F.
Medizinische Universitatsklinik und Poliklinik III Medizinische
Fakultat (Charité), Berlin, Germany .
4.00 pm MECHANISMS OF CORTICOSTEROID RESISTANCE IN RHEUMATOID ARTHRITIS
Chikanza I C, Thomas S, Pearce G J.
Bone & Joint Research Unit, Dept. of Rheumatology, Charterhouse Square,
London, UK.
4.30 pm IMMUNE HOMEOSTASIS REQUIRES SEVERAL BIOLOGIC FACTORS INCLUDING
GLUCOCORTICOID HORMONES (CTS)
Indiveri F.
Dept of Internal Medicine. University of Genova, Italy.
CHAIRMAN A T Masi
- Y Konttinen
5.00 - 5.30 pm Coffee Break and poster
viewing session
27. DOWNREGULATION OF GLUCOCORTICOID RECEPTORS IN EARLY DIAGNOSED RHEUMATOID
ARTHRITIS
Huisman A M, Van Everdingen A A, Wenting M J G, Lafeber F, Jacobs J W
G, Bijlsma J W J.
Rheumatology & Clinical Immunology, University Medical Center Utrecht,
Utrecht, The Netherlands.
41. DELAYED NEUTROPHIL APOPTOSIS INDUCED BY SYNOVIAL FLUID IN RHEUMATOID
ARTHRITIS ROLE OF CYTOKINES,ESTROGENS AND ADENOSINE
Ottonello L, Cutolo M1, Frumento G2, Arduino N3, Bertolotto M3, Mancini
M, Sottofattori E3, Dallegri F.
Division of Internal Medicine and 1Division of Rheumatology, Dept of Internal
Medicine, University of Genova, Italy; 3Dept of Pharmaceutical Sciences,
University of Genova,Italy; 2Immunogenetic Dept, National Institute of Cancer
Research, Advanced Biotechnology Center, Genova, Italy.
45. CAROTID ATHEROSCLEROSIS IN PATIENTS WITH RHEUMATOID ARTHRITIS: A CASE-CONTROL
STUDY
Rodriguez G, Sulli A1, Cutolo M1, Vitali P, Nobili F.
Clinical Neurophysiology and 1Rheumatology Divisions, DIMI, University
of Genova, Italy.
60. DO ESTROGEN AND PROGESTERONE PLAY A ROLE IN THE DRY EYE OF SJÖGREN’S
SYNDROME?
Suzuki T1,2, Schaumberg D A1,2,3, Sullivan B D1, Liu M1,2, Sullivan R
M1, Dana M R1,2,3, Sullivan D A1,2.
1Schepens Eye Research Institute, 2Harvard Medical School and 3Brigham
and Women’s Hospital, Boston, MA, USA.
54. DIFFERENTIAL MALE AND FEMALE ACTH AND CORTISOL RESPONSES TO INTERLEUKIN-6
IN HUMANS
Silva C, Inês L S, Nour D, 1Straub R H, Da Silva J A P.
Universidade de Coimbra, Portugal; 1University of Regensburg, Germany.
62. THE MEASUREMENT OF ANTI dsDNA ANTIBODIES AVIDITY BY ELISA METHOD:
A NEW APPROACH TO THE DIAGNOSISOF SLE
Villalta D1, Romelli P2, Doria A3, Ghirardello A3, Tozzoli R4, Bizzarro
N5, Tonutti E6, Bagnasco M7.
1Microbiology-Immunology Unit, Pordenone;2Bouty Laboratories, Milan; 3Division
of Rheumatology, Padua; 4Clinical Pathology, Latisana (UD); 5Clinical Pathology,
San Donà di Piave (VE); 6Clinical Pathology, Udine, 7DIMI, University
of Genova, Italy.
66. CHANGES IN LEVELS OF JOINT MARKERS OF HUMAN T-CELL LEUKEMIA VIRUS-I
CARRIERS WITH GONARTHROSIS
Yamaguchi T1, Shiraishi M1, Shirahama S2.
1Dept of Orthopedic Surgery, 2Dept of Internal Medicine, Kamigoto Hospital,
Nagasaki, Japan.
CHAIRMAN A Angeli –
F Minuto
6.00 -7.00 p.m. LECTURES
6.00 pm MECHANISMS OF GLUCOCORTICOID ACTION IN BONE
Canalis E.
Saint Francis Hospital and Medical Center, The University of Connecticut
School of Medicine, Hartford, CT, USA.
6.30 pm GLUCOCORTICOIDS IN RHEUMATOID ARTHRITIS: EFFECTS ON JOINTS
AND BONE
Bijlsma J W J, Everdingen A A van, Huisman A M, Nijs R, de, Jacobs
J W G.
Dept of Rheumatology and Clinical Immunology, University Medical Center,
Utrecht, The Netherlands.
9.00 pm GALA DINNER
Sunday September 23rd, 2001
Morning 9.00 am 1.00 pm
CHAIRMAN Y Konttinen – I C
Chikanza
9.00 - 11.00 pm LECTURES
9.00 am ANDROGEN DEFICIENCY MEIBOMIAN GLAND DYSFUNCTION
AND EVAPORATIVE DRY EYE IN SJÖGREN’SSYNDROME
Sullivan D A1, Sullivan B D1, Evans J E3 , Schirra F1, Yamagami H1, Liu
M1, Richards S1, Suzuki T1, Schaumberg D A, 1,2 , Sullivan R M1, Dana M
R1,2.
1Schepens Eye Research Institute (SERI) and Harvard Medical School, 2Brigham
and Women’s Hospital, Boston, and 3Eunice Kennedy Shriver Center, Waltham,
MA, USA.
9.30 am ANDROGENS AND ESTROGENS MODULATE THE IMMUNE AND INFLAMMATORY
RESPONSES IN RHEUMATOIDARTHRITIS
Cutolo M, Sulli A, Pizzorni C, Cerchi F, Craviotto C, Villaggio B, Grosso
M, Seriolo B.
Division of Rheumatology, Dept of Internal Medicine, University of Genova,
Italy.
10.00 am THE NEUROENDOCRINE ASPECTS OF CNS INVOLVMENT IN THE ANTI
PHOSPHOLIPID SYNDROME (APS)
Shoenfeld Y, Blank M, Chapman Y, Rauva L.
Center for Autoimmune Diseases, Dept of Medicine B, Caim Sheba Medical
Center, Tel-Hashomer, Sackler Faculty of Medicine, Tel-Aviv University, Israel.
10.30 am THE POSSIBLE ROLES OF MELATONIN IN INFLAMMATION/ AUTOIMMUNITY
Maestroni G J M.
Center for Experimental Pathology, Istituto Cantonale di Patologia, Locarno,
Switzerland.
CHAIRMAN R H Straub
- J W J Bijlsma
11.00 - 11.30 am Coffee Break and poster viewing session
15. INHIBITION OF GROWTH AND INDUCTION OF APOPTOSIS BY TESTOSTERONE
ON THE MONOCYTIC MYELOID CELL LINE (THP-1)
Cutolo M, Cerchi F, Sulli A, Pizzorni C, Craviotto C, Felli L, Rossoni
M, Seriolo B, Villaggio B.
Div. Rheumatology, Dept Int Medicine, Div Orthopedics, University of Genova,
Italy.
16. ANTIPROLIFERATIVE-ANTIINFLAMMATORY EFFECTS OF METHOTREXATE (MTX)
AND SEX HORMONES ON CULTUREDDIFFERENTIATING MYELOID MONOCYTIC CELLS
(THP-1)
Cutolo M, Cerchi F, Sulli A, Pizzorni C, Craviotto C, Seriolo B, Villaggio
B.
Div. Rheumatology, Dept Int Medicine, University of Genova, Italy.
2. REGULATION OF APOPTOSIS IN ENDOCRINE AUTOIMMUNITY: INSIGHTS FROM
HASHIMOTO’S THYROIDITIS AND GRAVES’ DISEASE
Bagnasco M1, Pesce G1, Montagna P1, Salmaso C1, Altrinetti V1, Richiusa
P2, Galluzzo A2, Giordano C2.
1DI.M.I. University of Genoa, 2Endocrinology, Institute of Clinica Medica,
University of Palermo, Italy.
51. SERUM OSTEOCALCIN LEVELS IN RHEUMATOID ARTHRITIS PATIENTS
Seriolo B, Fasciolo D, Ferretti V, Caratto E, Cutolo M.
Division of Rheumatology, Dept of Internal Medicine, University of Genova,
Italy.
52. THYROID DISEASE IN SYSTEMIC LUPUS ERYTHEMATOSUS AND RHEUMATOID
ARTHRITIS PATIENTS
Seriolo B, Fasciolo D, Ferretti V, Santaniello B1, Cutolo M.
Division of Rheumatology and 1Nuclear Medicine.
Dept of Internal Medicine, University of Genova, Italy.
53. PROLACTIN LEVELS IN RHEUMATOID PATIENTS WITH ANTIPHOSPHOLIPID
ANTIBODY POSITIVITY
Seriolo B, Fasciolo D, Ferretti V, Caratto E, Cutolo M.
Division of Rheumatology, Department of Internal Medicine, University
of Genova, Italy.
37. DHEAS LEVELS CORRELATES WITH DISEASE ACTIVIY IN GCA BUT NOT IN
PMR
Migliore A1, Pagano A, Latini A, Ragno A, Leoni M, Catucci A, Alimonti
A1, Martin LS.
1Dept of Internal Medicine, «San Pietro»- Fatebenefratelli
Hospital (Rome); Dept Of Internal Medicine «regina Apostolorum»
Hospital Albano Laziale , Rome, Italy
CHAIRMAN I C Chikanza
- A T Masi
11.30 -12.30 am SELECTED ORAL PRESENTATIONS
11.30 am SOMATOTROPHIC, LACTOTROPHIC AND ADRENOCORTICAL RESPONSES TO INSULIN-INDUCED
HYPOGLYCEMIAIN PATIENTS WITH RHEUMATOID ARTHRITIS
Rovensky J1, Bakosová J1, Koska J2, Ksinnantová L2, Jezová
D2, Vigas M2.
1Research Institute of Rheumatic Diseases, Piest’any and 2Institute
of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovak
Republic.
11.45. am 49. POST-MENOPAUSE IS THE MAIN RISK-FACTOR FOR DEVELOPING
PRIMARY PULMONARY HYPERTENSION IN SYSTEMIC SCLEROSIS
Scorza R, Caronni M, Bazzi S, Nador F1, Beretta L, Antonioli R, Origgi
L, Ponti A, Marchini M, Vanoli M.
Clinical Immunology and Allergology Unit, IRCCS Ospedale Maggiore and
University of Milan; 1Cardiology Unit, IRCCS Ospedale Maggiore di Milano,
Milano, Italy
12.00 am ROLE OF THE PINEAL GLAND AND MELATONIN IN THE DEVELOPMENT OF AUTOIMMUNE
DIABETES INNON-OBESE DIABETIC MICE
Conti A, Maestroni G J M.
Istituto Cantonale di Patologia, Center for Experimental Pathology, Locarno,
Switzerland.
12.15 am IMMUNE SYSTEM FUNCTION IN SYMPTOMATIC GULF WAR VETERANS
Everson M P, Shi K, Aldridge P, Bartolucci A A, Blackburn Jr W D.
Veterans Affairs Medical Center and Univ. Alabama at Birmingham, Birmingham,
Alabama, USA
12.30 am Conclusions
1.00 - 2.00 pm BUFFET
Scientific Secretariat
Maurizio Cutolo
Fax ++39 010 353 8885
Ph. ++39 010 353 7994
E-mail: mcutolo@unige.it
Division of Rheumatology
Dep. Internal Medicine and
Medical Specialities
University of Genova
Viale Benedetto XV, 6
16132 Genova - Italy
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Conference Secretariat
Studio Viale von der Goltz
Fax ++39 010 8318246
Ph. ++39 010 839 8462/873106
e-mail: viale@mbox.ulisse.it
Via Goito, 26/7
16122 Genova - Italy
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International Organizing
Committee
Maurizio Cutolo (Italy)
Alfonse T Masi (USA)
Johannes WJ Bijlsma (NL)
Robert G Lahita (USA)
Rainer H Straub (Germany)
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International Scientific
Committee
Thomas Bardin (France)
Gerd Burmester (Germany)
Ernesto Canalis (USA)
Luigi Castagnetta (Italy)
Ian Chikanza (UK)
Georges P Chrousos (USA)
Jean Michel Dayer (Switzerland)
José A Da Silva (Portugal)
Yrjö T Konttinen (Finland)
Francesco Indiveri (Italy)
Georges Maestroni (Switzerland)
Emilio M Mola (Spain)
Gunther Neeck (Germany)
Costantino Pitzalis (UK)
Josef Rowensky (Slovakia)
Juan J Scali (Argentina)
Yehuda Shoenfeld (Israel)
David Sullivan (USA)
Esther Sternberg (USA)
Ronald L Wilder (USA)
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Pagina principale
