There are a few things of notice, such as the time when Goku and Piccolo are forced to get driver's licenses by Chi-Chi. After the three years have passed, everybody goes to meet at the specific point given to them by Future Trunks. As it turns out, the island they were supposed to meet on contains a huge city.
The Z-Warriors are surprised to find Bulma there holding a baby (Trunks) in her hands. Goku mistakenly calls him Trunks before Bulma gives him the name, but since Trunks has already been born, there is no danger in revealing who he is. Since the Z-warriors cannot sense the KI of an android, they must look for the androids with their eyes and ears, and that may take a while. Eventually, Yamcha finds the androids, and is surprised to see what they look like, since no one ever got a description from Future Trunks. The androids quickly absorb Yamcha's energy through red orbs in their hands then promptly punch a gaping hole through Yamcha's stomach. The other Z-fighters eventually find Yamcha and fight a little with the androids, but soon give up, realizing that the fight is causing too many casualties. Yamcha is taking back to the original meeting place on the island (on a hill) and given a senzu bean, which revives him.
The androids and the Z-fighters all go to an island. Surprising, Goku is winded just from flying. Something is noticeably wrong with him. He begins to fight with android #19 and is whooping him up, but seems to be in worse and worse shape. Eventually the android overpowers him, and begins to absorb his energy. Piccolo is about to rescue him, when Vegeta rams into android #19 with a flying kick. The Z-warriors realize that the reason Goku is in such bad shape is because his heart condition is hurting him. As it turns out, he has never taken his medicine, because the symptoms never came. Yamcha takes him back to his house, where he is given the medicine. However, it seems to have little effect.
Meanwhile, back at the island, Vegeta has a few surprises of his own. Unbeknownst to the Z-fighters, Vegeta has acquired the ability to go Super Saiyan. He explains how ironic it was that his very anger at not being able to go Super Saiyan was the thing that caused him to go.. Vegeta and Android 19 fight around a bit, and it becomes clear that Vegeta has the upper hand. Eventually, Vegeta lets the android grab onto his arms, the Andriod begins to drain his energy saying "I'll never let go!" Vegeta asks "Never?" He places his feet on the android's chest and pulls its arms from their sockets. Vegeta then proceeds to destroy android 19.
Meanwhile, #20 is astonished that there can possibly be anybody this strong. He flees into a giant mountain, using the cracks to conceal himself, since the Z-fighters cannot sense his Ki. Vegeta is given Senzu and follows the android. The rest of the Z-fighters follow Vegeta. Android 20 is contemplating what to do. He decides to pick off the Z-fighters and steal their energy, then move on to Vegeta. He tries to steal Piccolo's energy, but since Piccolo has a supreme auditory system, he knows the attack was coming. Unbeknownst the android, Piccolo was actually destroying his energy while he thought he was absorbing it. Piccolo then takes a senzu and challenges #20 to a bout. 20 agrees, assuming he should be at least as strong as Piccolo after absorbing his energy. He gets the crap kicked out of him. He flees into the cracks of the mountain again and is going back to the lab.
Once Gero returns to the lab and attempts to persuade #17 and #18 to fight the Z teamers. The androids disagree, and don't like being commanded, and say so. The two androids decide to activate #16 despite many warnings from Dr. Gero. #17 and #18 kill Dr Gero. Vegeta states that that's not unusual, and that it is perfectly normal to kill anyone you don't like. Trunks shoots a blast into the cave which the lab is in, but it has no effect, #16 is activated. They ask him if he was made to kill Goku, and he replies to the affirmative. #18 says it makes her sick to think of Dr. Gero's goals for them.
The androids fly away, and the Z teamers realize they are heading towards Goku's house. Vegeta is mad the androids paid him no notice, and insists on following them despite numerous warnings from Trunks. Meanwhile the androids decide to touch down for a while. In a debate about taking a car, #17 asks #16 if he was made from a man like they were. #16 calmly states that he was made from nothing. The androids are puzzled over this for a little while, then Vegeta confronts them. #18 tells #16 to fight Vegeta, but he refuses.
#18 and Vegeta begin to duel, and #17 is surprised that the Saiyan is much stronger than Dr. Gero told them he was. All of the Z teamers return, and Vegeta comments on how stupid they are. #16 refuses to fight again. Trunks tells Vegeta to run, and the androids say they won't fight people who run away because they have no interest in them. Vegeta asks Trunks if he could use another slap. #17 complements Vegeta's fighting skills, but Vegeta just insults him in return. Piccolo notices that the android has infinite stamina, and Vegeta is getting weaker by the minute.
Vegeta never stood a total chance against #18 and she teaches him that as she kicks him in the arm... breaking it. Trunks yells out and rushes at #18. #17 had said earlier that if anyone else jumped in, he'd be forced to come in. Trunks goes super saiyaan and pulls his sword out on #18. But 18 only blocks Trunks's sword, chipping his sword. #17 and 18 make a total fool out of Vegeta, Piccolo, Tien, and Trunks. Krillin is frightened and stands there. After the androids have taken care of the other warriors, they walk to Krillin. #17's plan is to find Goku, but he wants to make sport of it so doesn't force Krillin to tell him. #18 kisses Krillin on the cheek and tells him good luck. Krillin is frightened and tries to talk the androids out of their so called 'game'. Their game plan is to destroy Goku. But the androids tell him they will not back down and leave Krillin. Krillin gives senzu' beans to the other downed warriors.
Piccolo goes off to combine with Kame, Vegeta heads off to train to reach a stronger level then a super saiyan, and Tien goes to train. Now Goku is healed and realizes what Vegeta is going to do. Piccolo has merged with Kame and is a Super Namek. He maintains as the strongest warrior on Earth for a little while. Goku gets Gohan, Trunks, and Vegeta and heads to the Time and Spirit Room to get a days training which will get you years worth of training. They already know about Cell and his diabolical scheme..