Skin has pigmentation, provided by melanocytes, which absorbs some of the potentially dangerous radiation in sunlight. It also contains DNA repair enzymes which reverse UV damage, and people who lack the genes for these enzymes suffer high rates of skin cancer. One form predominantly produced by UV light, malignant melanoma, is particularly invasive, causing it to spread quickly, and can often be deadly. Human skin pigmentation varies among populations in a striking manner. This has sometimes led to the classification of people on the basis of skin color. See the article on human skin color. The skin is often known as "the largest organ in the human body". This applies to exterior surface, as it covers the body, appearing to have the largest surface area of all the organs. Moreover, it applies to weight, as it weighs more than any single internal organ, accounting for about 15 percent of body weight. For the average adult human, the skin has a surface area of between 1.5-2.0 square metres, most of it is between 2-3 mm thick. The average square inch of skin holds 650 sweat glands, 20 blood vessels, 1000 melanocytes, and more than a thousand nerve endings. The outermost epidermis is consists of stratified squamous epithelium with an underlying basement membrane. It contains no blood vessels, and is nourished by diffusion from the dermis. The main type of cells which make up the epidermis are keratinocytes, with melanocytes and Langerhans cells also present. The epidermis can be further subdivided into the following strata (beginning with the outermost layer): corneum, lucidum, granulosum, spinosum, basale. Cells are formed through mitosis at the innermost layers. They move up the strata changing shape and composition as they differentiate, inducing expression of new types of keratin genes. They eventually reach the corneum and become sloughed off (desquamation). This process is called keratinization and takes place within about 30 days. This layer of skin is responsible for keeping water in the body and keeping other harmful chemicals and pathogens out. The main cell types of skin are fibroblasts, adipocytes (fat storage) and macrophages. Sebaceous glands are exocrine glands which produce sebum, a mixture of lipids and waxy substances: lubrication, water-proofing, softening and antibactericidal actions are among the many functions of sebum. Sweat glands open up via a duct onto the skin by a pore. The dermis can be split into the papillary and reticular layers. The papillary layer is outermost and extends into the dermis to supply it with vessels. It is composed of loosely arranged fibres. Papillary ridges make up the lines of the hands. The reticular layer is more dense and is continuous with the hypodermis. It contains the bulk of the structures (such as sweat glands). The reticular layer is composed of irregularly arranged fibres and resists stretching. The hypodermis is not part of the skin, and lies below the dermis. Its purpose is to attach the skin to underlying bone and muscle as well as supplying it with blood vessels and nerves. It consists of loose connective tissue and elastin. The main cell types are fibroblasts, macrophages and adipocytes (the hypodermis contains 50% of body fat). Fat serves as padding and insulation for the body. Skin can be dividided into thick and thin types. Thick skin is present on the soles of the feet and the palms of the hands. It has a larger stratum corneum with a higher keratin content. Thick skin does not grow hair; its purpose is to help grip. Thin skin is present on the bulk of the body and has a smaller stratum corneum and fewer papillae ridges. It has hair and is softer and more elastic. The characteristics of the skin, including sensory nerve density and the type of hair, vary with location on the body. Functions of the skin are disturbed when it is dirty and it becomes more easily damaged. The release of antibacterial compounds decreases. Dirty skin is more prone to develop infections. Cosmetics should be used carefully because these may cause allergic reactions. Each season requires suitable clothing in order to facilitate the evaporation of the sweat. Sunlight, water and air play an important role in keeping the skin healthy. The skin supports its own ecosystems of microorganisms, including yeasts and bacteria, which cannot be removed by any amount of cleaning. In general these organisms keep one another in check and are part of a healthy skin. When the balance is disturbed, e.g., by antibiotics which kill bacteria, there may be an overgrowth and infection by yeasts. The skin is continuous with the inner epithelial lining of the body at the orifices, each of which supports its own complement of flora.
In fact, skin care and protection should be an essential part of your health, fitness, and beauty regime. If you take care of your skin, your skin will take care of you! If your stuck in a skin care rut, or if you are just looking to learn a bit more about the basics of skin care, read on to learn more about this important step in your daily activities. You are never too young or too old to start taking care of your skin. In fact, skin care and protection should be an essential part of your health, fitness, and beauty regime. If you take care of your skin, your skin will take care of you! But with all of the lotions, creams, and potions on the market, it can be difficult to know which product will work for you. Many products claim to remove wrinkles or heal dry skin. Others claim to contain expensive ingredients that they say will improve the effects of the product. The most important way to care for your skin is to protect it from the damaging rays of the sun. Ultraviolet radiation damages the skin and can lead to wrinkles, premature aging, age spots, and cancer. Take extra precautions to make sure your skin is not exposed to the sun's rays. Use a natural sunscreen, or a moisturizer that contains sunscreen (at least SPF 15) everyday. Your skin does need some sunlight 10-15 minutes of direct exposure daily. When you do use soap, try using a natural very mild soap that does not contain any dyes, parabens or perfumes. Follow up the bath with a moisturizing lotion, concentrating on problem dry areas. A good all natural moisturizer is one of the foundations for a healthy skin care regimen. Continue moisturizing throughout the day to keep skin healthy. Your hands and face are particularly susceptible to daily damage, and may need to be moisturized several times. A skin care routine does not have to be elaborate in order to be effective. But you should develop some kind of skin care routine based on your skin type, daily activities, and nutritional needs so that you can be sure you are taking the very best care of your skin. Following a daily skin care regime will also allow you to more closely evaluate your skin for abnormalities. Apart from the services offered at skin clinics, many creams, gels and ointments that claim to treat acne, diminish sun or age spots and enhance skin elasticity are widely available in the market. There are scrubs, cleansers, masks, over-the-counter skin medicine and skin peel formulations, all offered at various price ranges. Most can be bought at department stores or drugstores, but the fact is that very few of these so- called miracle products actually work. Over the years, beauty experts and skin doctors have come up with a vast array products to treat and minimize wrinkles. Anti-wrinkle creams and ointments help reduce the appearance of wrinkles and prevent new ones from forming. These wrinkle ointments and anti-aging creams help a lot in restoring the skin's firmness and elasticity. In addition, these products contain anti-oxidants and retinol that not only aids in reducing wrinkles and fine lines on the skin, but also stimulates collagen production. For people seeking solutions to severe damage that has already been done to the skin, there are a number of treatments available ranging from chemical peels and dermabrasion to the latest and technologically advanced, computerized laser resurfacing. However, many people looking for skin repair are hesitant to try chemical or laser peels due to the painful procedure and long recuperation period they have to undergo. The results of these procedures however, are fantastic. One less painful procedure is the particle skin resurfacing procedure. The process is removes the outer layer of skin in a highly controlled manner. Because of its preciseness, it is practically painless. By repeating this procedure a number of times, the younger skin moves to the surface, thus promoting visible changes in the skin's texture, color and appearance. The benefits of this skin resurfacing procedure are that it causes very little pain or discomfort, no recuperative period is needed, there is minimal risk, it can be used for all skin types, and no anesthesia is required. While it is true that physical beauty is just skin deep, it is still no reason why people, particularly women, should disregard basic skin care. Since the skin is our outermost layer, it is exposed to the harsh elements of the environment. And because it is not uncommon for people to base judgments from our cover, with the face being the first thing they look at, it is only proper that we go to great lengths to keep our skin looking clean and fresh.

Definitions and termsAcne
- An inflammatory disease of the sebaceous glands and hair follicles of the skin that is marked by the eruption of pimples or pustules, especially on the face.
Bacteria
- Microscopic unicellular prokaryotic organisms characterized by the lack of a membrane-bound nucleus and membrane-bound organelles.
Dermis
- The sensitive connective tissue layer of the skin located below the epidermis, containing nerve endings, sweat and sebaceous glands, and blood and lymph vessels.
Epidermis
- The outer, protective, nonvascular layer of the skin of vertebrates, covering the dermis.
Hypodermis
- A subcutaneous layer of loose connective tissue containing a varying number of fat cells.
Pimples
- A small swelling of the skin, usually caused by acne; a papule or pustule.
Ultraviolet radiation
- Invisible electromagnetic radiation between visible violet light and X rays.
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