Kay Lee's
CANNABIS NOTES

 

Leading British Journals, The New Scientist And The Lancet, Cite The IOM Report — 2 Articles

Cannabis Basics
http://www.erowid.org/plants/cannabi...s_basics.shtml

10 Things Every Parent, Teenager & Teacher Should Know About Marijuana (4th Q)
http://www.erowid.org/plants/cannabi...s_flyer1.shtml

Marijuana Myths, Claim No. 9
http://www.erowid.org/plants/cannabi...is_myth9.shtml

Moderate cannabis use has a positive effect on treatment for cocaine
dependence in patients with comorbid ADHD and cocaine dependence
http://bbsnews.net/article.php/20061210235129584

Excerpt from the Merck Manual
http://www.ukcia.org/research/merck.htm

Relative Addictiveness of Various Substances
http://www.ukcia.org/research/addictiv.htm

Cannabis less harmful than drinking: report
World
03/10/2008 | Moscow News №39 2008
http://mnweekly.ru/world/20081003/55349604.html


LONDON (AFP) - Cannabis is less harmful than alcohol or tobacco, according to a report by a research charity Thursday, which called for a "serious rethink" of drug policy.

The Beckley Foundation, a charity which numbers senior experts and other academics among its advisors, said banning cannabis has no impact on supply and turns users into criminals.

"Although cannabis can have a negative impact on health, including mental health, in terms of relative harms it is considerably less harmful than alcohol or tobacco," says the report by the Foundation's Global Cannabis Commission.

The government is pressing for cannabis to be re-classified in law as a Class B drug compared with its current, less serious, Class C classification.

Authorities are concerned notably by the growing prevalence of the potent "skunk" form of the drug. Around 80 percent of cannabis seizures are of this strain, said to be linked to mental health problems, official figures show.

The Beckley Foundation, a charitable trust, claimed only two deaths worldwide have been attributed to cannabis, while alcohol and tobacco use together kill an estimated 150,000 people in Britain alone.

"Many of the harms associated with cannabis use are the result of prohibition itself, particularly the social harms arising from arrest and imprisonment," it said.

"It is only through a regulated market that we can better protect young people from the ever more potent forms of dope," it added.

The decision to reclassify cannabis upwards into the more punitive Class B category - which includes amphetamines - is a U-turn for the Labour government.
Cannabis was downgraded from Class B when Tony Blair was prime minister, but Gordon Brown announced a review of its status soon after taking over in June last year.

ADDICTION RISK- PHYSICAL

Women's Guide to the UofC
http://wguide.uchicago.edu/9substance.html

ADDICTION RISK- PHYSICAL

Women's Guide to the UofC
http://wguide.uchicago.edu/9substance.html
 

ALLERGIES TO CANNABIS

Sensitization and Allergy to Cannabis sativa Leaves in a Population of Tomato Sensitized Patients.
http://marijuana.researchtoday.net/archive/5/2/1629.htm

Allergic rhinoconjunctivitis caused by Cannabis sativa pollen
http://www.drugs-forum.com/forum/loc...=4823&catid=21
 

AMOTIVATIONAL SYNDROME

Amotivational Syndrome
http://leda.lycaeum.org/?ID=12454

Marijuana Myths, Claim No. 11
http://www.erowid.org/plants/cannab...is_myth11.shtml

Debunking 'Amotivational Syndrome'
http://www.mapinc.org/drugnews/v06/n400/a06.html

Debunking the Amotivational Syndrome
http://www.drugscience.org/Petition/C3F.html

Cannabis Use Not Linked To So-Called "Amotivational Syndrome"
http://www.norml.org/index.cfm?Grou...tm_format=print

ANECDOTAL / PERSONAL STORIES

Shared Comments and Observations
http://www.rxmarihuana.com/comments_...servations.htm

ANECDOTAL ARTICLES
http://cannabislink.ca/medical/#medanecdotal

Testimonials
http://www.benefitsofmarijuana.com/testimonials.html

Bud Buddies
http://budbuddies.com/buddy_testimonials.htm

ANTI-BACTERIAL PROPERTIES

Antibacterial Cannabinoids from Cannabis sativa
http://pubs.acs.org/cgi-bin/sample.c...np8002673.html

Killing bacteria with cannabis
http://arstechnica.com/journals/scie...-with-cannabis

Chemicals in Marijuana May Fight MRSA
http://www.webmd.com/news/20080904/m...may-fight-mrsa

ANALGESIC AND ANTI-INFLAMMATORY
ACTIVITY OF CONSTITUENTS OF CANNABIS SATIVA L.
http://www.ukcia.org/research/Analge...stituents.html

US Patent 6132762 - Transcutaneous application of marijuana
http://www.patentstorm.us/patents/6132762.html

Cannabis May Suppress Immune System
http://lupus.webmd.com/news/20030415...-immune-system

ANTI-INFLAMMATORY PROPERTIES

ANALGESIC AND ANTIINFLAMMATORY ACTIVITY OF CONSTITUENTS OF CANNABIS SATIVA L.
http://www.ukcia.org/research/Analge...stituents.html

Why Cannabis Stems Inflammation
http://www.sciencedaily.com/releases...0720222549.htm

Cannabidiol decreases bone resorption by inhibiting RANK/RANKL
expression and pro-inflammatory cytokines during experimental
periodontitis in rats.
http://www.unboundmedicine.com/medli...titis_in_rats_

ANTI- OXIDANT PROPERTIES

US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants
http://www.patentstorm.us/patents/6630507.html

CHEMICAL COMPOSITION

Cannabis: A source of useful pharma compounds
http://www.medpot.net/forums/index.php?showtopic=18608

Pharmacokinetics and cannabinoid action using oral cannabis extract
http://www.pharma-lexicon.com/medica...p?newsid=29638

The chemistry and biological activity of cannabis
http://www.unodc.org/unodc/en/bullet...html?print=yes

Differential effects of medical marijuana based on strain and route of administration
http://www.ukcia.org/research/DifferentialEffects/

Cannabis / Marijuana ( Δ 9 -Tetrahydrocannabinol, THC)
http://www.nhtsa.dot.gov/people/inju...s/cannabis.htm

A chemotaxonomic analysis of cannabinoid variation in Cannabis
http://www.amjbot.org/cgi/content/full/91/6/966

The inheritance of chemical phenotype in Cannabis sativa L.
http://www.genetics.org/cgi/reprint/163/1/335.pdf

Medical Cannabis Potency Testing Project
http://www.maps.org/news-letters/v09n3/09320gie.html

Compounds found in Cannabis Sativa
http://www.ukcia.org/research/cannabis-compounds.htm

Hemp Seed Oil : The Wonder Oil For the New Millennium
http://www.ukcia.org/research/Happi/...Millennium.htm

Composition of the essential oils and extracts of two populations of Cannabis sativa L. ssp. spontanea from Austria
http://findarticles.com/p/articles/m...s_/ai_n9299539

Non-cannabinoid constituents from a high potency Cannabis sativa variety.
http://www.unboundmedicine.com/medli...ativa_variety_

Cannabinoid Ester Constituents from High-Potency Cannabis sativa.
http://www.unboundmedicine.com/medli...nnabis_sativa_

CHILDREN/ YOUNG ADULTS

Experiences with THC-treatment in children and adolescents
http://www.cannabis-med.org/studies/...ow.php?s_id=80

An efficient new cannabinoid antiemetic in pediatric oncology.
http://www.cannabis-med.org/studies/...how.php?s_id=7

Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children
http://www.cannabis-med.org/studies/...w.php?s_id=120

Nabilone: an alternative antiemetic for cancer chemotherapy.
http://www.cannabis-med.org/studies/...w.php?s_id=123

Marijuana and ADD Therapeutic uses of Medical Marijuana in the treatment of ADD
http://www.onlinepot.org/medical/add&mmj.htm

Oily fish makes 'babies brainier'
http://news.bbc.co.uk/2/hi/health/4631006.stm

Cannabis is a First-Line Treatment for Childhood Mental Disorders
http://www.counterpunch.org/mikuriya07082006.html

Ganja use among Jamaican women.
http://www.rism.org/isg/dlp/ganja/an...njaBabyes.html

Dreher's Jamaican Pregnancy Study
http://www.november.org/stayinfo/bre...eherStudy.html

Medical marijuana: a surprising solution to severe morning sickness http://www.mothering.com/articles/pr...marijuana.html

Moderate cannabis use not harmful to the brain of adolescents, M R I study finds
http://www.cannabis-med.org/english/...l.php?id=218#3

No brain structural change associated with adolescent cannabis use
http://www.pubmedcentral.nih.gov/bot...&artid=1524733

No 'Smoking' Gun: Research Indicates Teen Marijuana Use Does Not Predict Drug, Alcohol Abuse
http://www.sciencedaily.com/releases...1204123422.htm

Pot May Not Shrink Teens' Brains After All
http://www.medpagetoday.com/Neurolog...rology/tb/3242

Swiss Study Finds Marijuana Use Alone May Benefit Some Teens
http://www.foxnews.com/story/0,2933,308258,00.html

Some go without a cigarette: characteristics of cannabis users who have never smoked tobacco.
http://marijuana.researchtoday.net/a.../4/11/1483.htm

Marijuana Use by Young People: The Impact of State Medical Marijuana Laws
http://www.mpp.org/research/teen-use-report.html

Recipe For Trouble (anecdotal)
http://www.cbsnews.com/stories/2002/...in503022.shtml

The association between anxiety and alcohol versus cannabis abuse disorders among adolescents in primary care settings
http://fampra.oxfordjournals.org/cgi...bstract/cmn049

Treatment with CBD in oily solution of drug-resistant paediatric epilepsies.
http://www.cannabis-med.org/studies/...ttern=EPILEPSY

DRIVING AND CANNABIS

New study from London's Transport Research Laboratory, and reported by Reuters:
http://www.reuters.com/article/lifestyleMolt/idUSLI65189720080918?sp=true

"The reaction times of people texting as they drove fell by 35 percent, while those who had consumed the legal limit of alcohol, or taken cannabis, fell by 21 percent and 12 percent respectively, according to the study."

Abstracts of several studies
http://www.ukcia.org/research/medline/8.htm

Cannabis and driving
http://www.ukcia.org/research/driving4.html

CANNABIS AND ROAD SAFETY
http://www.ukcia.org/research/driving2.htm

Marijuana And Actual Driving Performance
http://www.ukcia.org/research/driving.htm

Cannabis and Driving: A Scientific and Rational Review
http://norml.org/index.cfm?Group_ID=7459

Fitness to drive in spite (because) of THC
http://www.unboundmedicine.com/medli...use__of_THC%5D

DRONABINOL also see MARINOL

GENERIC NAME: DRONABINOL - ORAL (dro-NAB-in-all)
BRAND NAME(S): Marinol
http://www.medicinenet.com/dronabinol-oral/article.html

Dronabinol in the treatment of agitation in patients with Alzheimer’s disease with anorexia
http://www.cannabis-med.org/studies/...ow.php?s_id=61

Dronabinol in the treatment of refractory agitation in Alzheimer’s disease
http://www.cannabis-med.org/studies/...ow.php?s_id=92

Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease.
http://www.cannabis-med.org/studies/...ow.php?s_id=59

Dronabinol an effective appetite stimulant?
http://www.cannabis-med.org/studies/...w.php?s_id=188

Safety and efficacy of dronabinol in the treatment of agitation in patients with Alzheimer’s disease
http://www.cannabis-med.org/studies/...ow.php?s_id=61

Effect of dronabinol on nutritional status in HIV infection.
http://www.cannabis-med.org/studies/...w.php?s_id=150

Dronabinol stimulates appetite and causes weight gain in HIV patients.
http://www.cannabis-med.org/studies/...ow.php?s_id=20

Dronabinol effects on weight in patients with HIV infection.
http://www.cannabis-med.org/studies/...ow.php?s_id=45

Recent clinical experience with dronabinol.
http://www.cannabis-med.org/studies/...ow.php?s_id=90

Dronabinol enhancement of appetite in cancer patients.
http://www.cannabis-med.org/studies/...w.php?s_id=149

Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases.
http://www.cannabis-med.org/studies/...w.php?s_id=180

Dronabinol and prochlorperazine in combination
http://www.cannabis-med.org/studies/...ow.php?s_id=28

Dronabinol enhancement of appetite in cancer patients.
http://www.cannabis-med.org/studies/...w.php?s_id=149

Efficacy of dronabinol alone and in combination
http://www.cannabis-med.org/studies/...w.php?s_id=191

Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep.
http://www.cannabis-med.org/studies/...w.php?s_id=190

Dronabinol and retinal hemodynamics in humans.
http://www.cannabis-med.org/studies/...w.php?s_id=202

Dronabinol reduces signs and symptoms of idiopathic intracranial hypertension
http://www.cannabis-med.org/studies/...w.php?s_id=181

Nausea relieved by tetrahydrocannabinol (dronabinol).
http://www.cannabis-med.org/studies/...ow.php?s_id=35

Dronabinol in patients with intractable pruritus secondary to cholestatic liver disease.
http://www.cannabis-med.org/studies/...w.php?s_id=116

Treatment of spasticity in spinal cord injury with dronabinol
http://www.cannabis-med.org/studies/...w.php?s_id=112

Cannabinoid Activator Mellows Out Colon
http://www.medpagetoday.com/MeetingCoverage/ACG/tb/4410

Dronabinol and marijuana in HIV-positive marijuana smokers. Caloric intake, mood, and sleep.
http://marijuana.researchtoday.net/archive/4/8/1234.htm

Mayo Study: Marijuana's THC Reduces Stomach Cramping
http://bbsnews.net/article.php/20061029211046523

Improvement in Refractory Obsessive Compulsive Disorder With Dronabinol
http://ajp.psychiatryonline.org/cgi/...full/165/4/536

DRUG INTERACTIONS- see INTERACTIONS WITH OTHER DRUGS

DRUG TESTING

Hemp oil causes positive urine tests for THC
http://www.druglibrary.org/crl/drugt...JAnToxicol.pdf

Deposition of cannabinoids in hair after long-term use of cannabis
http://marijuana.researchtoday.net/archive/4/7/1002.htm

Cannabinoid concentrations in hair from documented cannabis users.
http://marijuana.researchtoday.net/archive/4/6/924.htm

Detection time of regular THC use in urine shorter than often assumed
http://www.acmed.org/english/bulleti...l.php?id=213#2

Differentiation between drug use and environmental contamination when testing for drugs in hair
http://www.sciencedirect.com/science...ad1bd10fb041bf

The effects of adulterants and selected ingested compounds on drugs-of-abuse testing in urine.
http://marijuana.researchtoday.net/archive/4/8/1389.htm

Roadside oral fluid testing: Comparison of the results of Drugwipe tests with laboratory
http://marijuana.researchtoday.net/archive/5/3/1351.htm

Toxicity From the Use of Niacin to Beat Urine Drug Screening
http://www.sciencedirect.com/science...9d8b53ea07c431

Evaluation of the IDS One-Step™ ELISA kits for the detection of illicit drugs in hair
http://www.sciencedirect.com/science...65bbd05717cb04

Deposition of cannabinoids in hair after long-term use of cannabis
http://www.sciencedirect.com/science...df7a40474cf025

Excretion of Δ9-tetrahydrocannabinol in sweat
http://www.sciencedirect.com/science...98c2e3fc4989d1

Portable Oral-Fluid Tests Still Unreliable For Pot, Study Says
http://norml.org/index.cfm?Group_ID=7636

Current Developments in Drug Testing in Oral Fluid.
http://www.drug-monitoring.com/pt/re/tdm/abstract.00007691-200804000-00010.h;jsessionid=LRvN2KXBJJQrJPTMBgn4LnynJxnJby0
RpLL7mSfp7JGR3m0cj8bS!-1809387994!181195628!8091!-1

Drug-Test Cheats Try New Tricks on Labs
http://www.webmd.com/mental-health/n...tricks-on-labs

 

 

 

 

GATEWAY THEORY

The Myth of Marijuana's Gateway Effect
http://www.druglibrary.org/schaffer/library/mjgate.htm

Endogenous cannabinoids are not involved in cocaine reinforcement
http://www.sciencedirect.com/science...4e861a90579fac

No 'Smoking' Gun: Research Indicates Teen Marijuana Use Does Not Predict Drug, Alcohol Abuse
http://www.sciencedaily.com/releases...1204123422.htm

CLAIM #13:MARIJUANA IS A "GATEWAY" TO THE USE OF OTHER DRUGS
http://www.erowid.org/plants/cannabi...s_myth13.shtml

Gateway To Nowhere? The Evidence That Pot Doesn't Lead To Heroin
http://www.thehempire.com/index.php/...lead_to_heroin

Cannabis use when it's legal
http://www.sciencedirect.com/science...96c8de7949a364

Cannabis Use- A Gateway to other Drugs? The Case of Amsterdam
http://www.ukcia.org/research/Cannab...ppingStone.pdf

Twin study fails to prove 'gateway' hypothesis
http://www.ukcia.org/research/Escala...veGateway.html

HISTORICAL STUDIES/ HISTORY

The La Guardia Committee Report
http://www.druglibrary.org/schaffer/...ag/lagmenu.htm

Physical, Mental, and Moral Effects of Marijuana: The Indian Hemp Drugs Commission Report
http://www.druglibrary.org/schaffer/Library/effects.htm

MARIAJUANA SMOKING IN PANAMA
http://www.druglibrary.org/schaffer/...ma/panama1.htm

The British Pharmaceutical Codex – 1934
http://www.druglibrary.org/schaffer/...cal/brit34.htm

ON THE PREPARATIONS OF THE INDIAN HEMP, OR GUNJAH
http://www.druglibrary.org/schaffer/...850/gunjah.htm

DISPENSATORY OF THE UNITED STATES OF AMERICA Fifth Edition (1843)
http://www.druglibrary.org/schaffer/...y/dispensa.htm

New Remedies:Pharmaceutically and Therapeutically Considered Fourth Edition (1843)
http://www.druglibrary.org/schaffer/...y/dunglisn.htm

On the Haschisch or Cannabis Indica
http://www.druglibrary.org/schaffer/...y/bellhash.htm

ON INDICATIONS OF THE HACHISH-VICE IN THE OLD TESTAMENT
http://www.druglibrary.org/schaffer/...ory/hashot.htm

The Physiological Activity of Cannabis Sativa
http://www.druglibrary.org/schaffer/...story/japa.htm

CANNABIS, U.S.P. (American Cannabis):
http://www.druglibrary.org/schaffer/...y/vbchmed1.htm

History of Cannabis and Its Preparations in Saga, Science and Sobriquet
http://www3.interscience.wiley.com/c...06128/PDFSTART

HORMONES

Effects of chronic marijuana use on testosterone, luteinizing hormone,
follicle stimulating hormone, prolactin and cortisol in men and women.
http://www.ncbi.nlm.nih.gov/pubmed/1935564

Marijuana: interaction with the estrogen receptor
http://jpet.aspetjournals.org/cgi/co...ract/224/2/404

Endocrine Effects of Marijuana
http://www.ukcia.org/research/EndocrineEffects.pdf

INTERACTIONS WITH OTHER DRUGS

Efficacy of dronabinol alone and in combination
http://www.cannabis-med.org/studies/...w.php?s_id=191

Dronabinol and prochlorperazine in combination
http://www.cannabis-med.org/studies/...ow.php?s_id=28

Cannabinoids, in combination with (NSAIDS), produce a synergistic analgesic effect
http://www.medjournal.com/forum/show...87&postcount=1

Add-on treatment with the synthetic cannabinomimetic nabilone on patients with chronic pain
http://www.cannabis-med.org/studies/...w.php?s_id=197

Synergistic affective analgesic interaction between delta-9-tetrahydrocannabinol and morphine.
http://www.cannabis-med.org/studies/...w.php?s_id=178

The analgesic properties of delta-9-tetrahydrocannabinol and codeine.
http://www.cannabis-med.org/studies/...ow.php?s_id=17

Synergy between Delta(9)-tetrahydrocannabinol and morphine in the arthritic rat
http://www.unboundmedicine.com/medli..._arthritic_rat

Cannabis reduces opioid dose in the treatment of chronic non-cancer pain.
http://www.cannabis-med.org/studies/...w.php?s_id=148

Medicinal cannabis does not influence the clinical pharmacokinetics of irinotecan and docetaxel.
http://www.cannabis-med.org/studies/...rn=INTERACTION

IQ/ MEMORY/ COGNATIVE EFFECTS

Findings of a longitudinal study of effects on IQ
http://www.cmaj.ca/cgi/content/full/166/7/887

Heavy cannabis use without long-term effect on global intelligence
http://www.cannabis-med.org/english/...l.php?id=115#2

Marijuana does not dent IQ permanently
http://www.newscientist.com/article/...rmanently.html

Cannabis use and cognitive decline in persons under 65 years of age
http://www.ukcia.org/research/Cannab...veDecline.html

Differential Effects of THC or CBD-rich Cannabis Extracts on Working Memory in Rats
http://www.ukcia.org/research/THCCBDWorkingMemory.pdf

Neurocognitive performance during acute THC intoxication in heavy and occasional cannabis users.
http://www.unboundmedicine.com/medli...annabis_users_

Non-acute (residual) neurocognitive effects of cannabis use: a meta-analytic study.
http://www.ncbi.nlm.nih.gov/pubmed/12901774

Review: executive functioning and cannabis use.
http://www.unboundmedicine.com/medli...nnabis_use_%5D

LONG TERM USE EFFECTS

Long-Term Marijuana Users Suffer Few Health Problems, Australian Study Indicates
http://www.ukcia.org/research/aus.htm

Neuropsychological Performance in Long-term Cannabis Users
http://www.ukcia.org/research/Neurop...nabisUsers.htm

Long term marijuana users seeking medical cannabis in California
http://www.harmreductionjournal.com/content/4/1/16

MORTALITY RATES

Marijuana use and mortality.
http://www.pubmedcentral.nih.gov/art...?artid=1380837

Marijuana Smoking Doesn't Lead to Higher Death Rate
http://ccrmg.org/journal/03sum/kaiser.html

How deadly is marijuana?
http://www.medicalnewstoday.com/articles/4426.php

NABILONE GENERIC NAME:

NABILONE

GENERIC NAME: NABILONE - ORAL (NAB-ih-lone)
Brand Names : Cesamet
http://www.medicinenet.com/nabilone-oral/article.htm

The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients
http://www.cannabis-med.org/studies/...w.php?s_id=177

Nabilone versus prochlorperazine
http://www.cannabis-med.org/studies/...w.php?s_id=120

Nabilone: an alternative antiemetic for cancer chemotherapy.
http://www.cannabis-med.org/studies/...w.php?s_id=123

Antiemetic efficacy of nabilone and alizapride
http://www.cannabis-med.org/studies/...w.php?s_id=127

Nabilone versus domperidone
http://www.cannabis-med.org/studies/...w.php?s_id=129

Comparison of nabilone and prochlorperazine
http://www.cannabis-med.org/studies/...w.php?s_id=128

Nabilone vs. prochlorperazine for refractory emesis
http://www.cannabis-med.org/studies/...w.php?s_id=146

Nabilone vs. placebo
http://www.cannabis-med.org/studies/...w.php?s_id=156

Effects of nabilone and prochlorperazine on chemotherapy-induced emesis
http://www.cannabis-med.org/studies/...w.php?s_id=131

Superiority of nabilone over prochlorperazine
http://www.cannabis-med.org/studies/...w.php?s_id=126

Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children
http://www.cannabis-med.org/studies/...w.php?s_id=120

Nabilone: an alternative antiemetic for cancer chemotherapy.
http://www.cannabis-med.org/studies/...w.php?s_id=123

Effect of nabilone on nausea and vomiting after total abdominal hysterectomy
http://www.cannabis-med.org/studies/...w.php?s_id=137

Nabilone improves pain and symptom management in cancer patients
http://www.cannabis-med.org/studies/...w.php?s_id=177

Synthetic cannabinomimetic nabilone on patients with chronic pain
http://www.cannabis-med.org/studies/...w.php?s_id=197

Nabilone significantly reduces spasticity-related pain
http://www.cannabis-med.org/studies/...w.php?s_id=200

Nabilone on L-DOPA induced dyskinesia in patients with idiopathic Parkinson's disease
http://www.cannabis-med.org/studies/...w.php?s_id=153

Nabilone in the treatment of multiple sclerosis.
http://www.cannabis-med.org/studies/...ow.php?s_id=11

Nabilone significantly reduces spasticity-related pain
http://www.cannabis-med.org/studies/...w.php?s_id=200

Analgesic effect of the cannabinoid analogue nabilone
http://www.cannabis-med.org/studies/...w.php?s_id=203

Nabilone in the treatment of multiple sclerosis
http://www.cannabis-med.org/studies/...ow.php?s_id=11

Comparison of nabilone and metoclopramide in the control of radiation-induced nausea.
http://www.cannabis-med.org/studies/...w.php?s_id=130

Nabilone and metoclopramide in the treatment of nausea and vomiting
http://www.cannabis-med.org/studies/...w.php?s_id=121

Nabilone: an alternative antiemetic for cancer chemotherapy.
http://www.cannabis-med.org/studies/...w.php?s_id=123

Comparison of the antiemetic efficacy of nabilone and alizapride
http://www.cannabis-med.org/studies/...w.php?s_id=127

Nabilone versus domperidone in the treatment of cytotoxic-induced emesis.
http://www.cannabis-med.org/studies/...w.php?s_id=129

Add-on treatment with the synthetic cannabinomimetic nabilone on patients with chronic pain -
http://www.cannabis-med.org/studies/...w.php?s_id=197

Comparison of bronchial effects of nabilone and terbutaline
http://www.cannabis-med.org/studies/...ow.php?s_id=43

Nabilone Could Treat Chorea and Irritability in Huntington’s Disease
http://neuro.psychiatryonline.org/cg...18/4/553?rss=1

Cannabis Science: Nabilone reduced chronic pain caused by fibromyalgia
http://bbsnews.net/article.php/20071111150357312

Nabilone for the treatment of pain in fibromyalgia.
http://www.ncbi.nlm.nih.gov/pubmed/17974490

NEUROPROTECTANT

Marijuana Protects Your Brain
http://www.roninpub.com/art-mjbrain.html

The neuroprotective effect of cannabinoids in a rat model of Parkinson's disease
(may need free registration)
http://www.medscape.com/medline/abstract/17196181

Neuroprotective and Intraocular Pressure-Lowering Effects of (-)Delta-THC
http://www.unboundmedicine.com/medli...el_of_Glaucoma

Neuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol
http://www.unboundmedicine.com/medli..._peroxynitrite

Neuroprotection induced by Delta(9)-tetrahydrocannabinol in AF5 cells
http://www.unboundmedicine.com/medli...l_in_AF5_cells

Cannabidiol has a cerebroprotective action
http://www.unboundmedicine.com/medli...ting_mechanism

Cannabidiol but not Delta(9)-THC has a neuroprotective effect without the development of tolerance..
http://www.unboundmedicine.com/medli...t_of_tolerance

Delta(9)-THC) prevents cerebral infarction
http://www.unboundmedicine.com/medli...nt_hypothermia

Delta(9)-Tetrahydrocannabinol protects hippocampal neurons from excitotoxicity
http://www.unboundmedicine.com/medli...excitotoxicity

Cannabis and Neuroprotection
http://www.pacifier.com/~alive/cmu/c...protection.htm

Neuroprotection by Delta 9-THC against Ouabain-Induced In Vivo Excitotoxicity
http://www.jneurosci.org/cgi/content...urcetype=HWCIT

Cannabinoids and Neuroprotection in Global and Focal Cerebral Ischemia and in Neuronal Cultures
http://www.jneurosci.org/cgi/content...urcetype=HWCIT

Cannabinoid activation of PPARalpha; a novel neuroprotective mechanism
http://www.nature.com/bjp/journal/v1.../0707478a.html

The use of cannabinoids in MS: is it evidence based?
http://www.ukcia.org/research/UseOfC...denceBased.pdf

Neurons on Cannabinoids: Dead or Alive?
http://www.ukcia.org/research/NeuronsDeadOrAlive.pdf

Cannabinoids and Brain Injury: Therapeutic Inplications
http://www.ukcia.org/research/Cannab...rainInjury.pdf

Cannabidiol and delta 9THC are neuroprotective antioxidants
http://www.ukcia.org/research/Neurop...tioxidants.pdf

NUTRITION

Oily fish makes 'babies brainier' (hemp seed- at the very end)
http://news.bbc.co.uk/2/hi/health/4631006.stm

Efficacy of dietary hempseed oil in patients with atopic dermatitis. (may need free registration)
http://www.medscape.com/medline/abst...yText=hempseed

Effects of smoked marijuana on food intake and body weight
http://www.cannabis-med.org/studies/...w.php?s_id=117

Characterization, amino acid composition and in vitro digestibility of hemp (Cannabis) proteins
http://www.sciencedirect.com/science...a3209943890e39

HEMP SEED: THE MOST NUTRITIONALLY COMPLETE FOOD SOURCE IN THE WORLD (1)
http://www.ratical.org/renewables/hempseed1.html

HEMP SEED: THE MOST NUTRITIONALLY COMPLETE FOOD SOURCE IN THE WORLD (2)
http://www.ratical.org/renewables/hempseed2.html

Hemp seed oil: A source of valuable essential fatty acids
http://www.hempfood.com/IHA/iha03101.html

Occurrence of "omega-3" stearidonic acid in hemp seed
http://www.hempfood.com/IHA/iha03208.html

Hemp Seed Oil : The Wonder Oil For the New Millennium
http://www.ukcia.org/research/Happi/...Millennium.htm

Cannabis butter to spread across Europe
http://www.globalhemp.com/News/2004/...bis_butter.php

Hempseed as a nutritional resource: An overview
http://www.finola.com/HempseedNutrition.pdf

PATENTS RELATED TO CANNABIS

US Patent 7344736 - Extraction of pharmaceutically active components from plant materials
http://www.patentstorm.us/patents/7344736/fulltext.html

US Patent 6630507 - Cannabinoids as antioxidants and neuroprotectants
http://www.patentstorm.us/patents/6630507.html

US Patent 6328992 - Cannabinoid patch and method for cannabis transdermal delivery
http://www.patentstorm.us/patents/6328992.html

US Patent 6949582 - Method of relieving analgesia and reducing inflamation using a cannabinoid delivery topical liniment
http://www.patentstorm.us/patents/6949582/fulltext.html

US Patent 7402686 - Cannabinoid crystalline derivatives and process of cannabinoid purification
http://www.patentstorm.us/patents/7402686/fulltext.html

US Patent 6713048 - Δ9 tetrahydrocannabinol (Δ9 THC) solution metered dose inhalers and methods of use
http://www.patentstorm.us/patents/6713048/fulltext.html

US Patent 6974568 - Treatment for cough
http://www.patentstorm.us/patents/6974568/fulltext.html

US Patent 7088914 - Device, method and resistive element for vaporizing a medicament
http://www.patentstorm.us/patents/7088914/fulltext.html

US Patent 7399872 - Conversion of CBD to Δ-THC and Δ-THC
http://www.patentstorm.us/patents/7399872/fulltext.html

US Patent 6383513 - Compositions comprising cannabinoids (nasal spray)
http://www.patentstorm.us/patents/6383513/fulltext.html

US Patent 6132762 - Transcutaneous application of marijuana
http://www.patentstorm.us/patents/6132762.html

US Patent 4189491 - Tetrahydrocannabinol in a method of treating glaucoma
http://www.patentstorm.us/patents/4189491.html

QUITTING OTHER DRUGS

Crack heads and roots daughters: The therapeutic use of cannabis in Jamaica (cocaine)
http://www.cannabis-med.org/studies/...w.php?s_id=260

Role of cannabinoid receptors in alcohol abuse
http://www.medicalnewstoday.com/articles/30338.php

Cannabidiol, Antioxidants, and Diuretics in Reversing Binge Ethanol-Induced Neurotoxicity
http://jpet.aspetjournals.org/cgi/co...urcetype=HWCIT

Cannabis substitution (alcohol)
http://www.cannabis-med.org/studies/...ow.php?s_id=86

Cannabis as a Substitute for Alcohol
http://ccrmg.org/journal/03sum/substitutealcohol.html

SAFETY

Proven: Cannabis is safe medicine
http://www.ukcia.org/research/safe-medicine.htm

Excerpt from the Merck Manual
http://www.ukcia.org/research/merck.htm

Medical use of cannabinoids does not cause an increase in serious adverse health effects
http://www.cmaj.ca/cgi/content/full/178/13/1685

Claims Linking Health Problems And The Strength Of Cannabis May Be Exaggerated
http://www.sciencedaily.com/releases...0617125751.htm

SAFETY-ADULTERANTS/ CONTAMINANTS

Smoke Pot, Get Lead Poisoning? (Germany/Europe)
http://www.webmd.com/news/20080409/s...lead-poisoning

Neuropsychological effects of formaldehyde use
http://www.unboundmedicine.com/medli...maldehyde_use_

#Microbiological contaminants of marijuana
http://www.hempfood.com/IHA/iha01205.html

SATIVEX

Questions and Answers About SATIVEX® Liquid Medical Marijuana
http://www.mpp.org/library/questions...al-mariju.html

Sativex in the treatment of pain caused by rheumatoid arthritis
http://rheumatology.oxfordjournals.o...stract/45/1/50

Sativex produced significant improvements in a subjective measure of spasticity
http://www.cannabis-med.org/studies/...w.php?s_id=170

Sativex in patients suffering from multiple sclerosis associated detrusor overactivity
http://www.cannabis-med.org/studies/...w.php?s_id=168

Sativex showed positive effects in 65 per cent of patients with chronic diseases
http://www.cannabis-med.org/english/...l.php?id=230#4

Cannabis; adverse effects from an oromucosal spray.
http://marijuana.researchtoday.net/archive/4/8/1357.htm

Cannabis, pain, and sleep: lessons from trials of Sativex, a cannabis-based medicine.
http://marijuana.researchtoday.net/archive/4/8/1384.htm

Sativex successfully treats neuropathic pain characterised by allodynia
http://www.sciencedirect.com/science...143cfe474843b1

SLEEP MODULATION

Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats. (may need free registration)
http://www.medscape.com/medline/abst...44117?prt=true

Dronabinol reduces signs and symptoms of idiopathic intracranial hypertension
http://www.cannabis-med.org/studies/...w.php?s_id=181

Cannabis-based medicine in central pain in multiple sclerosis.
http://www.cannabis-med.org/studies/...w.php?s_id=175

Two cannabis based medicinal extracts for relief of central neuropathic pain
http://www.cannabis-med.org/studies/...ow.php?s_id=15

Functional role for cannabinoids in respiratory stability during sleep
http://www.pacifier.com/~alive/cmu/c...leep_apnea.htm

THC reduces sleep apnoea in animal research
http://www.cannabis-med.org/english/...l.php?id=120#1

Cannabis, pain, and sleep: lessons from trials of Sativex, a cannabis-based medicine.
http://marijuana.researchtoday.net/archive/4/8/1384.htm

Dronabinol and marijuana in HIV-positive marijuana smokers. Caloric intake, mood, and sleep.
http://marijuana.researchtoday.net/archive/4/8/1234.htm

Effect of illicit recreational drugs upon sleep: Cocaine, ecstasy and marijuana.
http://www.ncbi.nlm.nih.gov/pubmed/1...t=AbstractPlus

The nonpsychoactive cannabis constituent cannabidiol is a wake-inducing agent.
http://www.unboundmedicine.com/medli...nducing_agent_

SMOKED CANNABIS AS A MEDICATION

Fitness to drive in spite (because) of THC
http://www.unboundmedicine.com/medli...use__of_THC%5D

The perceived effects of smoked cannabis on patients with multiple sclerosis.
http://www.cannabis-med.org/studies/...ow.php?s_id=13

Effects of smoked marijuana on food intake and body weight
http://www.cannabis-med.org/studies/...w.php?s_id=117

Effects of smoked marijuana in experimentally induced asthma.
http://www.cannabis-med.org/studies/...ow.php?s_id=57

Smoked marijuana and oral delta-9-THC on specific airway conductance in asthmatic subjects
http://www.ukcia.org/research/Smoked...nAsthmatic.php

The effects of smoked cannabis in painful peripheral neuropathy
http://www.cannabis-med.org/studies/...ow.php?s_id=96

Inhalation marijuana as an antiemetic for cancer chemotherapy.
http://www.cannabis-med.org/studies/...w.php?s_id=155

Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy
http://www.medmjscience.org/Pages/science/pierson.html

Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep.
http://www.cannabis-med.org/studies/...w.php?s_id=190

The perceived effects of smoked cannabis on patients with multiple sclerosis.
http://www.cannabis-med.org/studies/...ow.php?s_id=13

Epilepsy patients are smoking pot
http://www.safeaccessnow.org/article.php?id=1638

Anticonvulsant nature of marihuana smoking
http://www.cannabis-med.org/studies/...ow.php?s_id=39

Marijuana Smoking vs Cannabinoids for Glaucoma Therapy
http://archopht.ama-assn.org/cgi/con...ct/116/11/1433

Marihuana smoking and intraocular pressure.
http://www.cannabis-med.org/studies/...ow.php?s_id=47

SOCIAL ADJUSTMENT

Some go without a cigarette: characteristics of cannabis users who have never smoked tobacco.
http://marijuana.researchtoday.net/a.../4/11/1483.htm

Marijuana use motives and social anxiety among marijuana-using young adults.
http://marijuana.researchtoday.net/archive/4/8/1303.htm

TAXONOMY

History of Cannabis and Its Preparations in Saga, Science and Sobriquet
http://www3.interscience.wiley.com/c...06128/PDFSTART

TEA AS MEDICINE

Cannabis tea revisited: A systematic evaluation
http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum

Cuppa Gives A Better 'ooh'
http://www.thehempire.com/index.php/...s_a_better_ooh

With the use of cannabis tea only a small proportion of THC in the cannabis is ingested
http://www.ohiopatient.net/v2/content/view/906/37/

THC/ TETRAHYDROCANNABINOL

Physicians, Cannabis Cooperatives and Dispensaries

TOBACCO VS CANNABIS

Cannabis Smoke and Cancer: Assessing the Risk
http://www.norml.org/index.cfm?Group_ID=6891

Cannabis and tobacco smoke are not equally carcinogenic
http://www.pubmedcentral.nih.gov/art...?artid=1277837

Smoking Marijuana Does Not Cause Lung Cancer
http://www.mapinc.org/drugnews/v05/n1065/a03.html

Tobacco and marijuana use on offspring growth from birth through 3 years of age.
http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum

Progression from marijuana use to daily smoking and nicotine dependence
http://www.erowid.org/references/refs_view.php?ID=6951

High anxieties - What the WHO doesn't want you to know about cannabis
http://www.newscientist.com/article/...-cannabis.html

Radioactive tobacco
http://www.cannabisculture.com/news/tobacco/

Some go without a cigarette: characteristics of cannabis users who have never smoked tobacco.
http://marijuana.researchtoday.net/a.../4/11/1483.htm

Cannabis use when it's legal
http://www.sciencedirect.com/science...96c8de7949a364

Aluminum in Tobacco and Cannabis and Smoking-Related Disease
http://www.sciencedirect.com/science...14cf03f3b4bc4e

Marijuana Improves Fertility in Tobacco Smokers
http://news.softpedia.com/news/Marij...rs-41535.shtml

TOLERANCE

A Molecular Basis of Analgesic Tolerance to Cannabinoids
http://www.jneurosci.org/cgi/content...urcetype=HWCIT

Cancer-related anorexia-cachexia syndrome
http://www.unboundmedicine.com/medli...ia_Study_Group

THC effective in appetite and weight loss in severe lung disease (COPD)
http://www.cannabis-med.org/english/...l.php?id=191#2

The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat
http://www.unboundmedicine.com/medli...inoid_receptor

Synergy between Delta(9)-tetrahydrocannabinol and morphine in the arthritic rat
http://www.unboundmedicine.com/medli..._arthritic_rat

Bronchial effects of aerosolized delta 9-tetrahydrocannabinol
http://www.cannabis-med.org/studies/...w.php?s_id=109

Bronchodilator effect of delta1-tetrahydrocannabinol administered by aerosol
http://www.cannabis-med.org/studies/...ow.php?s_id=60

Effects of smoked marijuana in experimentally induced asthma.
http://www.cannabis-med.org/studies/...ow.php?s_id=57

Marijuana and oral delta9-tetrahydrocannabinol on specific airway conductance
http://www.cannabis-med.org/studies/...ow.php?s_id=67

New Synthetic Delta-9-THC Inhaler Offers Safe, Rapid Delivery
http://www.medicalnewstoday.com/articles/22937.php

Smoked marijuana and oral delta-9-THC on specific airway conductance in asthmatic subjects
http://www.ukcia.org/research/Smoked...nAsthmatic.php

Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme.
http://www.cannabis-med.org/studies/...w.php?s_id=193

9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer
http://cancerres.aacrjournals.org/cg...act/66/13/6615

THC and prochlorperazine effective in reducing vomiting in women following breast surgery
http://www.cannabis-med.org/english/...l.php?id=219#1

{Delta}9-Tetrahydrocannabinol-Induced Apoptosis in Jurkat Leukemia T Cells
http://mcr.aacrjournals.org/cgi/cont...stract/4/8/549

Delta(9)-THC) prevents cerebral infarction
http://www.unboundmedicine.com/medli...nt_hypothermia

Medical marijuana: study shows that THC slows atherosclerosis
http://thenexthurrah.typepad.com/the...l_marijua.html

Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects
http://www.cannabis-med.org/studies/...ow.php?s_id=10

The effect of delta-9-THC on human spasticity.
http://www.cannabis-med.org/studies/...w.php?s_id=154

The treatment of spasticity with D9-THC) in patients with spinal cord injury
http://www.cannabis-med.org/studies/...ow.php?s_id=79

Delta-9-THC as an alternative therapy for overactive bladders in spinal cord injury
http://www.cannabis-med.org/studies/...w.php?s_id=102

The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity
http://www.cannabis-med.org/studies/...ow.php?s_id=12

The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury.
http://www.cannabis-med.org/studies/...w.php?s_id=166

Delta-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition
http://www.unboundmedicine.com/medli..._and_Cognition

Marihuana as a therapeutic agent for muscle spasm or spasticity.
http://www.cannabis-med.org/studies/...ow.php?s_id=53

Analgesic effect of delta-9-tetrahydrocannabinol.
http://www.cannabis-med.org/studies/...ow.php?s_id=16

The analgesic properties of delta-9-tetrahydrocannabinol and codeine.
http://www.cannabis-med.org/studies/...ow.php?s_id=17

The perceived effects of smoked cannabis on patients with multiple sclerosis.
http://www.cannabis-med.org/studies/...ow.php?s_id=13

Cannabis use for chronic non-cancer pain
http://www.cannabis-med.org/studies/...ow.php?s_id=91

Tetrahydrocannabinol for treatment of chronic pain
http://www.cannabis-med.org/studies/...w.php?s_id=147

Delta-9-THC based monotherapy in fibromyalgia patients
http://www.cannabis-med.org/studies/...w.php?s_id=194

Delta(9)-THC) prevents cerebral infarction
http://www.unboundmedicine.com/medli...nt_hypothermia

Delta(9)-Tetrahydrocannabinol protects hippocampal neurons from excitotoxicity
http://www.unboundmedicine.com/medli...excitotoxicity

THC effective in intractable nausea in a patient undergoing gastric bypass surgery
http://bbsnews.net/article.php/2008020313112065

Differential Effects of THC or CBD-rich Cannabis Extracts on Working Memory in Rats
http://www.ukcia.org/research/THCCBDWorkingMemory.pdf

Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy
http://www.medmjscience.org/Pages/science/pierson.html

Delta-9-Tetrahydrocannibinol as an Antiemetic in Cancer Patients Receiving High-Dose Methotrexate
http://www.medmjscience.org/Pages/science/chang.html

Neurocognitive performance during acute THC intoxication in heavy and occasional cannabis users.
http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum

THC ACID/ THCA

Production of THC acid by the biosynthetic enzyme secreted from transgenic Pichia pastoris.
http://marijuana.researchtoday.net/archive/4/8/1331.htm

VAPORIZERS

Vaporization as a smokeless cannabis delivery system
http://www.cannabis-med.org/studies/...w.php?s_id=187

Smokeless Cannabis Delivery Device Efficient And Less Toxic
http://www.medicalnewstoday.com/articles/71112.php

Volcano is to Vaporizer As Porsche is to Automobile
http://ccrmg.org/journal/04spr/volcano.html

Recommendation to Patients: "Don’t smoke, Vaporize"
http://ccrmg.org/journal/03sum/vaporize.html

Decreased respiratory symptoms in cannabis users who vaporize.
http://marijuana.researchtoday.net/archive/4/4/1195.htm

Use of vaporizers reduces toxins from cannabis smoke
http://www.cannabis-med.org/english/...l.php?id=146#2

Marijuana Water Pipe and Vaporizer Study
http://www.ukcia.org/research/pipes.htm

Effect of intrapulmonary tetrahydrocannabinol administration in humans.
http://marijuana.researchtoday.net/archive/5/8/1816.htm

US Patent 7088914 - Device, method and resistive element for vaporizing a medicament
http://www.patentstorm.us/patents/7088914/fulltext.html

WITHDRAWAL SYNDROME

Excerpt from the Merck Manual
http://www.ukcia.org/research/merck.htm

Pot, Tobacco Withdrawal Equally Rough
http://www.webmd.com/mental-health/n...-equally-rough

YOUNG ADULTS- see CHILDREN/YOUNG ADULTS

Prohibition is the scam

Physicians, Cannabis Cooperatives and Dispensaries

Orange County Seniors Demand Medical Marijuana Access (video)

 

Wiley InterScience
http://www3.interscience.wiley.com/cgi-bin/fulltext/121398289/PDFSTART
Pharmacological and therapeutic secrets of plant and brain (endo)cannabinoids
Lumír Ondej Hanu ^*
Medicinal Research Reviews
Volume 29, Issue 2 , Pages213 - 271
Copyright © 2009 Wiley Periodicals, Inc., A Wiley Company

email: Lumír Ondej Hanu (lumir@cc.huji.ac.il)

^*Correspondence to Lumír Ondej Hanu, Department of Medicinal Chemistry and Natural Products, School of Pharmacy, Faculty of Medicine, Hebrew University, Ein Kerem Campus, Jerusalem 91120, Israel.

Abstract

Department of Medicinal Chemistry and Natural Products, School of Pharmacy, Faculty of Medicine, Hebrew University, Ein Kerem Campus, Jerusalem 91120, Israel.

Research on the chemistry and pharmacology of cannabinoids and endocannabinoids has reached enormous proportions, with approximately 15,000 articles on Cannabis sativa L. and cannabinoids and over 2,000 articles on endocannabinoids.  

The present review deals with the history of the Cannabis sativa L. plant, its uses, constituent compounds and their biogeneses, and similarity to compounds from Radula spp. 

In addition, details of the pharmacology of natural cannabinoids, as well as synthetic agonists and antagonists are presented.  

Finally, details regarding the pioneering isolation of the endocannabinoid anandamide, as well as the pharmacology and potential therapeutic uses of endocannabinoid congeners are presented. 

(c) 2008 Wiley Periodicals, Inc. Med Res Rev., 29, No. 2, 213-271, 2009

9

Looking Forward,  Kay Lee