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Obesity is defined as having an abnormal increase of body fat which is also called adipose tissue mass. An obese person is 20 percent or more above desirable weight. In the last decade obesity has been on the rise in both women and men. Fat distribution can influence a person's risk of disease. Fat carried around the waist and in the abdominal area, characterized by the "apple shape", is associated with an increased risk for many medical problems such as heart disease, cancer, high blood pressure, and diabetes. Fat that is mostly distributed around the buttocks and thighs is associated with a lower risk of developing these diseases. As much as 50 to 75 percent of obesity has genetic influences. Just what those genetic influences are that affect body weight have not been identified. Medically supervised fasts are very low calorie diets which provide from 400 to 800 calories per day. While most of these diets are low in calories, the protein provision is very high. The purpose of these diets is to promote fat loss, not muscle loss. The high protein content helps prevent large losses of muscle tissue. Electrolytes, vitamins and minerals are also supplemented. To achieve lasting weight loss, commitment must be given to making real changes in eating patterns. Individuals are who not committed will gain back their weight. During the holidays or when celebrating, many of us have overeaten. But some people have problems controlling their appetite and end up eating non-stop until eating is interrupted. During a binge, 10,000 to 20,000 calories can be consumed throughout the day. Binges usually consist of foods like cookies, candy, chips, ice cream and many other high calorie foods. Binges are often done in secret. After a binge, many of the feelings that caused the binge, like stress, may have subsided only to be replaced with feelings of guilt and lack of self-control. Bulimia nervosa is an eating disorder that is estimated to be present in up to 5 percent of teenage and young adult women. It is characterized by binge eating followed by purging and other behaviors such as vomiting. Laxatives, diet pills, water pills, exercise or fasting may also be used.
The medications most often used in the management of obesity are commonly known as "appetite suppressant" medications. Appetite suppressant medications promote weight loss by increasing metabolism and by decreasing appetite or increasing the feeling of being full. These medications work by increasing the serotonin and/or catecholamine - two brain chemicals that affect mood, appetite and metabolism. The most recent drug in the fight against obesity is Xenical. A new class of non-systemic anti-obesity drug called lipase inhibitors which act in the gastrointestinal tract to prevent the absorption of fat by about 30 percent. Drugs in this class do not achieve their effect through brain chemistry or central nervous system stimulation. In other words, Xenical is not an appetite suppressant or metabolic inducer. While the FDA regulates how a medication can be advertised or promoted by the manufacturer, these regulations do not restrict a doctor's ability to prescribe the medication for different conditions, in different doses, or for different lengths of time. People respond differently to appetite suppressant medications, and some people experience more weight loss than others. Some obese patients using medication lose more than 10 percent of their starting body weight- an amount of weight loss that may reduce risk factors for obesity - related diseases, such as high blood pressure or diabetes. When considering long-term appetite suppressant medication treatment for obesity, you should consider the following areas of concern and potential risks. Currently, all prescription medications to treat obesity are controlled substances, meaning doctors need to follow certain restrictions when prescribing appetite suppressant medications. Although abuse and dependence are not common with non-amphetamine appetite suppressant medications, doctors should be cautious when they prescribe these medications for patients with a history of alcohol or other drug abuse. However obesity, is more appropriately considered a chronic disease than a lifestyle choice. Other chronic diseases, such as diabetes, and high blood pressure, are managed by long-term drug treatment, even though these diseases also improve with changes in lifestyle, such as diet and exercise. Although this issue may concern physicians and patients, social views on obesity should not prevent patients from seeking medical treatment to prevent health risks that can cause serious illness and death.
Definitions and terms on this pageFDA
- Food and Drug Administration: A government agency that oversees public safety in relation to drugs and medical devices. The FDA gives approval to pharmaceutical companies for commercial marketing of their products.
Fat blocker
- Drugs that block the absorption of fat or calories, and lose substantial weight.
Overweight
- Weighing more than is normal, necessary, or allowed, especially having more body weight than is considered normal or healthy for one's age or build.
Appetite
- An instinctive physical desire, especially one for food or drink. Decreased desire to eat is termed anorexia, while polyphagia (or "hyperphagia") is increased eating. Disregulation of appetite contributes to anorexia nervosa and cachexia, or oppositely, overeating.
Diabetes
- Any of several metabolic disorders marked by excessive discharge of urine and persistent thirst, especially one of the two types of diabetes mellitus.
Diet
- A regulated selection of foods, as for medical reasons or cosmetic weight loss.
- A solutions designed to reduce or suppress the appetite.
Fat
- Any of various soft, solid, or semisolid organic compounds constituting the esters of glycerol and fatty acids and their associated organic groups.
Obesity
- The condition of being obese; increased body weight caused by excessive accumulation of fat.
Stress
- A state of extreme difficulty, pressure, or strain.
- A physical and psychological response that results from being exposed to a demand or pressure.
Suppress
- To curtail or prohibit the activities of.
- To inhibit the expression of (an impulse, for example).
- To bring to an end forcibly as if by imposing a heavy weight.
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