* Conference Event
% Scrimmage Event
| August |
| | 23 | Midwestern State University | @ | Oklahoma City | 6-1 |
| | preseason scrimmage |
| | 27 | Oklahoma Christian | @ | Oklahoma City | 0-1 |
| | 29 | Oklahoma Baptist | @ | Ozark Christian College | 11-1 |
| | 30 | Oklahoma Wesleyan | @ | John Brown | 1-3 |
| | | Science & Arts | @ | Northwood (Texas) | 2-0 |
| | | Friends | @ | Oklahoma Christian | 0-4 |
| | 31 | Hillsdale Free Will Baptist College | @ | Oklahoma Baptist | 0-11 |
| September |
| | 1 | Science & Arts | @ | Oklahoma City | 1-3 |
| | 2 | John Brown | @ | Northwood University | 1-2 |
| | | Oklahoma Baptist | @ | Texas A&M International | 3-1 |
| | 3 | Oklahoma Baptist | vs. | Schreiner University | 1-0 |
| | | Mid-Continent | @ | Southern Nazarene | 0-4 |
| | | Oklahoma City | @ | Texas Wesleyan | 3-0 |
| | 5 | Mid-Continent | @ | St. Gregory's | 8-0 |
| | 6 | Oklahoma Baptist | @ | Bethany (Kan.) | |
| | | Science & Arts | @ | McPherson | |
| | | Southern Nazarene | @ | Oklahoma Christian | |
| | 7 | Missouri Valley | @ | John Brown | |
| | 8 | Oklahoma City | @ | Newman | |
| | 9 | Hastings | @ | Southern Nazarene | |
| | | Oklahoma Baptist | @ | Mobile | |
| | 2005 University of Mobile Futbol Festival |
| | 10 | John Brown | @ | Concordia (Neb.) | |
| | | Science & Arts | @ | Friends | |
| | | Hastings | @ | Oklahoma Christian | |
| | | St. Gregory's | @ | Texas A&M International | |
| | | Oklahoma Baptist | vs. | Auburn Montgomery | |
| | 2005 University of Mobile Futbol Festival |
| | 13 | Bethany (Kan.) | @ | John Brown | |
| | | Oklahoma City | @ | Southern Nazarene | |
| | | Science & Arts | @ | Oklahoma Christian | |
| | 16 | Oklahoma City | vs. | Dakota Wesleyan | |
| | Siloam Springs, Ark. |
| | | Southwest | @ | Oklahoma Baptist | |
| | | Azusa Pacific | @ | Southern Nazarene | |
| | | John Brown | vs. | Trinity International | |
| | 23rd Annual JBU Fall Classic |
| | | Oklahoma Christian | @ | Oral Roberts University | |
| | 17 | John Brown | vs. | Dakota Wesleyan | |
| | 23rd Annual JBU Fall Classic |
| | | Oklahoma City | vs. | Trinity International | |
| | Siloam Springs, Ark. |
| | | Azusa Pacific | vs. | Oklahoma Baptist | |
| | | Southwest | @ | Southern Nazarene | |
| * | 20 | St. Gregory's | @ | Science & Arts | |
| | | West Texas A&M | @ | Oklahoma City | |
| | | Bethany (Kan.) | @ | Southern Nazarene | |
| | | Northwood (Texas) | @ | Oklahoma Christian | |
| | | Oklahoma Baptist | @ | Southwestern | |
| | 21 | University of Central Arkansas | @ | John Brown | |
| | 22 | Oklahoma City | @ | Friends | |
| | | Southern Nazarene | vs. | Texas Wesleyan | |
| | 23 | Sterling | @ | Oklahoma Baptist | |
| | | Bethany (Kan.) | @ | Science & Arts | |
| | | McPherson | @ | Oklahoma Christian | |
| | | Texas A&M International | @ | Southern Nazarene | |
| | 24 | McPherson | @ | Oklahoma Baptist | |
| | | Park | @ | John Brown | |
| | | Texas A&M International | @ | Science & Arts | |
| | | Bethany (Kan.) | @ | St. Gregory's | |
| | | Sterling | @ | Oklahoma Christian | |
| | 25 | Oklahoma City | @ | Southwestern University | |
| | 27 | Bacone | @ | Science & Arts | |
| * | | St. Gregory's | @ | Oklahoma Christian | |
| | 28 | Missouri Southern State University | @ | John Brown | |
| * | 29 | St. Gregory's | @ | Oklahoma City | |
| * | 30 | Science & Arts | @ | Southern Nazarene | |
| October |
| * | 1 | Oklahoma Christian | @ | Oklahoma Baptist | |
| | | Tabor | @ | John Brown | |
| * | 3 | Oklahoma City | @ | Oklahoma Christian | |
| | 4 | Missouri Valley | @ | St. Gregory's | |
| * | | Oklahoma Baptist | @ | Science & Arts | |
| | 5 | Missouri Valley | @ | Oklahoma City | |
| | 6 | Friends | @ | Southern Nazarene | |
| * | 8 | Southern Nazarene | @ | John Brown | |
| * | | Oklahoma Baptist | @ | Oklahoma City | |
| | | Texas Wesleyan | @ | Oklahoma Christian | |
| | 11 | Oklahoma City | @ | Hendrix College | |
| * | | Oklahoma City | @ | John Brown | |
| | | Science & Arts | @ | John Brown | |
| * | | Southern Nazarene | @ | St. Gregory's | |
| | | Newman | @ | Oklahoma Christian | |
| * | 13 | John Brown | @ | St. Gregory's | |
| | 14 | St. Gregory's | @ | Texas-Permian Basin | |
| * | 15 | Southern Nazarene | @ | Oklahoma City | |
| | | Science & Arts | @ | Texas Wesleyan | |
| * | 18 | Oklahoma Christian | @ | Science & Arts | |
| * | | Oklahoma Baptist | @ | Southern Nazarene | |
| * | 21 | St. Gregory's | @ | Oklahoma Baptist | |
| * | | Oklahoma City | @ | Science & Arts | |
| | 22 | Southern Nazarene | @ | Park | |
| * | | John Brown | @ | Oklahoma Christian | |
| * | 25 | John Brown | @ | Oklahoma Baptist | |
| * | | Science & Arts | @ | St. Gregory's | |
| * | | Oklahoma Christian | @ | Southern Nazarene | |
| | 29 | John Brown | @ | TBA | |
| | SAC Tournament |
* Conference Event
% Scrimmage Event