People in our laboratory are interested in three major questions;
How protein degradation is regulated in lymphocytes, cancer and ES cells, and what causes recurrent spontaneous abortion (RSA) and polycystic ovarian syndrome (PCOS). In addition, we are investigating the biological roles of lgl oncogene family members. We use a combination of molecular and genetic approaches as well as immunological approach to investigate these questions.

 Overview of Laboratory Projects 

1. Deubiquitinating Enzymes (DUBs)
2. Recurrent Spontaneous Abortion (RSA) & Polycystic Ovarian Syndrome (PCOS)
3. Recessive Oncogene lgl Family Members

Present

1. À¯ÀüÀÚ º¯ÀÌ ¹è¾Æ°£¼¼Æ÷ ´ë·®»ý»ê ¹× DUB À¯ÀüÀÚ »ýü³» ±â´É ºÐ¼®
   (Supported by Korea Institute of S&T Evaluation and Planning: 2002.10 - 2005.06)

2. Improvment of Preimplantation Embryo Development by the Regulation of Protein Degradation
   (Supported by Ministry of Health & Welfare: 2002.07 - 2004.04)

3. Genome Research Center for Reproductive Medicine and Infertility
   (Supported by Ministry of Health & Welfare: 2001.12 - 2010.11)

4. Development of Novel Technologies in Reproductive Medicine: Ovum Bank, Oocyte Microsurgery, Innovative Embryo Culture System and Specific Cell Lineage Production Using Embryonic Stem Cells
   (Supported by Korea Science and Engineering Foundation: 1999.09 - 2004.08)

Past

1. The Role of Deubiquitinating Enzymes in Lymphocyte Signal Transduction
   (Supported by Korea Research Foundation: 1999.12 - 2000.11)

2. Deubiquitinating Enzyme Studies on Leukemia Development
   (Supported by Korea Research Foundation: 2000.09 - 2001.08)

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