| NAME | ORIGIN | REFERENCE | PROPERTIES |
| NAME | ORIGIN | REFERENCE | PROPERTIES |
| Feldomite | Naturally occurring. | DS9: Business As Usual | A valuable substance recently and unexpectedly found on Parsion III. |
| Felicium | Naturally occurring. | TNG: Symbiosis | A substance produced from plants by the people of Brekka. It was once used to cure a deadly plague. It also has addictive properties. |
| Ferric oxide | Naturally occurring. | VOY: The 37'S | Ferric oxide corrodes iron particles into rust. |
| Fistrium | Naturally occurring. | TNG: Silicon Avatar | Refractory metal found in caves of Melona IV. Theorized that the prescence of fistrium and kelbonite prevented the Crystalline Entity from scanning the caves. |
| Fortanium | Naturally occurring. | TNG: Masks | Used in the composition of the informational archive at the comet's core. |
| NAME | ORIGIN | REFERENCE | PROPERTIES |
| Gallicite | Naturally occurring. | VOY: Blood Fever | Gallicite is a rare substance which can be used to refit warp coils. |
| Gallium arsenide | Origin unknown. | TNG: Home Soil | Gallium arsenide was one of the impurities found on Velara III. |
| Garnesite | Naturally occurring. | VOY: Parturition | Paris and Neelix fire their phasers at these rocks in order to get a little heat and light in the cave. |
| Gold-pressed Latinum | Origin unknown. | DS9: all | A non-replicatable material, typically pressed into bars, like gold and used as a form of currency. |
| Golside ore | Origin unknown. | DS9: The Maquis, Part I | An ore which Dukat claimed the Bok'Nor had just delivered 14 metric tons of to the Regulon system before stopping at DS9. |
| NAME | ORIGIN | REFERENCE | PROPERTIES |
| Hydrazine | Artifically generated by crew. | VOY: The Coda | There was a hydrazine gas leak in the shuttle after it is struck by lightning; they evacuate the shuttle after the hydrazine levels reach 112 parts per million. |
| Hydrocortilene | Artificially generated by crew. | VOY: The Swarm | The Doctor tells Kes to prepare a hypospray with 3% hydrocortilene to treat Torres's headache. |
| Hyronalin | Artificially generated by crew. | VOY: Real Life | The Doctor gives Paris a combination of hyronalin and lectrazine to give him temporary protection from radiation poisoning. |
| Hyttrium | Naturally occurring. | TNG: The Most Toys | Only known cure for tricyanate contamination of water supplies. Highly volatile.Used to explode a shuttlecraft so that Kivas Fajo could kidnap Data without suspicion. |
| NAME | ORIGIN | REFERENCE | PROPERTIES |
| Ilium 629 | Naturally occurring. | TNG: Pen Pals | A by-product of the geological decay of dilithium. Traces of ilium 629 were found on the planet Drema IV, leading to the discovery of unusual dilithium deposits in the planet's mantle. The dilithium transformed the planet's geological heat into mechanical stress, resulting in significant tectonic instabilities that nearly destroyed the planet. The geological instabilities were neutralized by the use of resonator probes launched from orbit. |
| Impedrezene | Artificially generated by crew. | VOY: Alliances | The Doctor gives Bendera 75 cc's of this drug to try to stimulate his cardiac functions. |
| Improvoline | Artificially generated by crew. | VOY: Basics, Part 2 | The Doctor wants to give Suder 5 cc's of improvoline to calm him down after he has had to kill a Kazon. |
| Inapprovaline | Artificially generated by crew. | VOY: Lifesigns | Kes suggests that they stimulate cell regeneration by giving Denara Pel a high dosage of inapprovaline; the Doctor says it is too late for that. |
| Infernite | Origin unknown. | DS9: In the Hands of the Prophets | When mixed with carbrodine, becomes explosive. |
| Invidium | Origin unknown. | TNG: Hollow Pursuits | Used in medical containment fields the previous century. No longer used. Causes adverse reactions with equipment. It affected the magnetic capacitors on the antimatter injector and an un-named component in the transporter. |
| Iridium | Naturally occurring. | TOS: Requiem for Methesulah | A heavy element of the platinum group. The iridium rendered the Ritalin inert and therefore unusable in combating an epidemic that the crew was trying to prevent on another planet. |
| Isoboromine | Naturally occurring. | DS9: Equilibrium | A neurotransmitter in Trills which maintains the link between symbiont and host. If its level gets too low, the symbiont must be removed or it will die. Dax had a low isoboromine count from the hallucinations of Joran Dax. |
| NAME | ORIGIN | REFERENCE | PROPERTIES |
| Jakmanite | Naturally occurring. | TNG: Hollow Pursuits | Like invidium, jakmanite cannot be detected by internal sensors. Exists in oxygen environment, and like invidium, can alter advanced structures like glass. Duffy ruled jakmanite out as a possible cause of the problems experienced by the Enterprise crew. |
| Jevonite | Naturally occurring. | TNG: Chain of Command Part II | Valuable gemstone found on Cardassia. Ancient jevonite artifacts found on Cardassia were sold or stolen by the army to finance the war effort. |
| NAME | ORIGIN | REFERENCE | PROPERTIES |
| Kayolane | Artificially generated by aliens. | TNG: Identity Crisis | A sedative. Beverly inoculates Leijten with kayolane after the latter's blood chemistry changes and after she exhibits strange behavior. |
| Kelbonite | Naturally occurring. | TNG: Silicon Avatar | Refractory metal found in caves of Melona IV. Data thought the prescence of kelbonite and fistrium prevented the Crystilline Entity from scanning caves. |
| Kelotane | Artificially generated by crew. | VOY: State of Flux | The Doctor tells Kes to prepare 3 cc's of kelotane when Seska is beamed back to Voyager after she is injured on the Kazon ship. |
| Kemacite | Origin unknown. | DS9: Little Green Men | An illegal substance which Quark was going to smuggle to Orion on the way back from Earth. Its reaction to vented plasma from the warp core triggered a time warp. |
| Ketracel White | Artificially generated by aliens. | DS9: many | A vital, isogenic enzyme needed for the survival of the Jem'Hadar. The enzyme can only be provided by the Founders, and currently cannot be reproduced by the Federation. The Founders engineered the Jem'Hadar's addiction to this enzyme to ensure their loyalty to the Dominion. |
| Kironide | Artificially generated by aliens. | TOS: Plato's Stepchildren | Induces telekinetic powers. Platonians used it to hold Enterprise crew captive and force them to perform for their amusement. McCoy synthesized the chemical so crew could escape. |
| Koranium | Origin unknown. | DS9: Blood Oath | Subspace element used in Klingon warp drives. Mentioned briefly as being a part of warp drive in the injectors. |
| NAME | ORIGIN | REFERENCE | PROPERTIES |
| Lactic acid | Naturally occurring. | VOY: Sacred Ground | The Doctor detects a gradual buildup of lactic acid in Janeway's extensor muscles over the last few hours which indicates that she is experiencing a light strain. |
| Ladarium | Artificially generated by aliens. | DS9: Tribunal | A substance used in Cardassian warp engines. Boone told O'Brien that he was now running a ladarium mining sluice on Volan III. |
| Lectrazine | Artificially generated by crew. | VOY: Lifesigns | The Doctor orders 20 milligrams of this after the Vidiian is transported to sick bay. Lectrazine is used to try to counteract the disruptions in her cardiac functions. |
| Lexorin | Artificially generated by crew. | ST: TSFS | A seditive. When Kirk visits McCoy in the brig he brings lexorin to help make the ride easier. |
| Lucrovexitrin | Origin unknown. | TNG: Hollow Pursuits | Highly toxic; alters molecular structure when it comes in contact with glass. Exists in a Nitrogen-Oxygen atmosphere. |
| Lydroxide corrosive | Artificially generated by the crew. | VOY: Rise | This is a coolant used in the tether couplings; Vatm was poisoned when someone put this in the water supply. |
| NAME | ORIGIN | REFERENCE | PROPERTIES |
| Magnasite | Naturally occuring. | DS9: Nor the Battle to the Strong | Prevents Federation transporters to beam through it. |
| Meranium | Artificially generated by aliens. | TNG: The Vengeance Factor | A metal alloy. Its melting point is 2014 degrees Fahrenheit. The away team fired their phasers into the meranium alloy, causing a smoke screen. |
| Mercassium | Artificially generated by crew. | DS9: The Maquis, Part I | A synthetic composite used by the Federation in the construction of shield generators. Traces of it were found in the debris of the destroyed Bok'Nor. |
| Merculite | Artificially generated by aliens. | TNG: Suddenly Human | An explosive material used in out-of-date rockets which are no match for Federation weaponry. |
| Minzinite | Origin unknown. | DS9: Statistical Probabilities | Several deposists were found on Holna IV. |