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Adrenal Insuff.

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bulletPresentation
bulletGuy from San Franscisco, HIV +
bulletSomeone who got the "flu" and never bounced back
bulletHistory
bulletPrevious illnesses, fatigue, diarrhea, cramps
bulletDepression, dizziness, anorexia, weight loss, nausea
bulletIrritiblility, restlessness, psychosis
bulletDizzy when stand, skin pigmentation increased, difficulty recovering                         from stress
bulletPE
bulletVitals:  hypotensive, tachycardic, do orthostatics
bulletHEENT:  pigmentation of oral mucosa
bulletCV: do a regular exam
bulletLungs: auscultate
bulletSkin: hyperpigmentation
bulletNeuro: mental status check
bulletDDx
bulletHypothyroidism
bulletLaboratory
bulletCBC w/ diff, BMP, UA, stat glucose,
bulletTSH, 24-hour urine cortisol, 8 am cortisol, ACTH level
bulletACTH stimulation test (normal minimal respose is to go greater                                 than 20)
bulletEKG, CXR
bulletTreatment
bulletAdmit to telemetry
bulletIV fluids: make sure you have dextrose in your fluids
bulletSteroid replacement: hydrocortisone, fludrocortisone
bulletMiscellanous
bulletMost common causes of adrenal insufficiency
bulletAddison's
bulletCMV, TB, other fungal infections, Kaposi's, cryptococcus
bulletSarcoidosis, bilateral adrenal hemorrhage with Waterhouse-Friedrichsen syndrome (dissemminated gonococcus)