Starting off with a bang after last season's climatic closer, this episode held me in through the story and made me groan at the end. Being an X-Phile for the paranormal uniqueness of the show, I was enjoying the case at hand and disappointed at the "shippy" ending. Like I said before, I did love the X-File: Chris Carter hasn't had a good human experimentation case in a long time. The DNA lacing and contaminating nature of Piora was intriguing, while I actually found myself saddened at the death of the character we had so many problems with.
In light of the web of lies that encircled Michael Piora, I continue to wonder what really went on with him and Bill, Jr., make him lie about Piora's relation to the Scullys. The answer of questions with more questions definitely gave me the feel that I was actually in fact reading something of an X-Files script written by the writers themselves. The X-File was well thought and executed in a fine manner, the details of everything fitting in perfect with the story.
The conclusion of the episode could have ran smoother, personally I would have felt better if Scully's virus was slowly terminated after a few weeks after the cure was taken in. It almost seemed too unbelievable for there to be a cure for a deadly virus that does miracles in seconds. Of course every writer has their own vision and no man (or woman for that matter) should disrupt that. This was just my two cents.