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Acceptable regimens in the presence of apparent MDR TB
(WHO recommendation)
Situation A:Susceptibility test results are not available before starting the new treatment:
Initial phase
Continuation phase
Drugs
Minimum duration in months
Drugs
Duration in months
1
Aminoglycosidea
3
Ethionamide
18
2
Ethionamide
3
Ofloxacin
18
3
Pyrazinamide
3
4
Ofloxacin b
3
a)Kanamycin or amikacin or Capreomycin b)The daily dose of 800mg can be reduced to 400mg if poorly tolerated.If ofloxacin is not available,use cycloserine