Illinois 157 is a mostly north-south running route from Cahokia north to IL140 at Hamel, in the I-55 corridor.

Intersections from north to south: IL140 at Hamel

IL157 joins IL143 west at Edwardsville

IL157 goes southwest as IL159 comes from the south and follows IL143 northwest

I-270 near Glen Carbon

IL162 near Glen Carbon

I-55 near Collinsville

I-64

IL161

IL15

IL157 joins IL13 west

(I find the background pretty funny)

IL13 ends at IL163 as IL157 joins IL163 south

IL163 breaks off

I-255/US50 near Cahokia

IL3 in Cahokia

It passes through these towns: Hamel, Edwardsville, Collinsville, Glen Carbon, Caseyville, Edgemont, East St. Louis, Glen Carbon, Centreville, Cahokia.

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