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Mad cow disease, also called
bovine spongiform encephalopathy, causes decay in the brain. It is known
to affect cows and there is debate about whether or not it can cause
disease in people, too.
What is going on in the body? The disease causes a type of
organism known as a prion to build up in the brain. This prion build up
causes brain injury and degeneration.
The Creutzfeldt-Jakob disease (CJD) is a human prion disease. Mad cow
disease is seen in cows. There is disagreement about whether or not mad
cow disease occurs in people, too. Some question whether or not mad cow
disease in people may be linked to a new variant of CJD.
In 1996, this new variant occurred in a number of people in the United
Kingdom, some younger than the age group usually affected by CJD.
A strong link between mad cow disease and the new variant of CJD is
now suspected. Most believe that this new variant CJD is the human form
of mad cow disease.
What are the symptoms of this disease, take note of the following
symptoms.
- fatigue and disordered sleep
- memory loss and confusion
- psychiatric and behavioral problems
- altered sensation
- difficulty with walking and movement
- vision loss
- difficulty talking
- paralysis
The known cause and risk of this is disease is the prion diseases
is prion proteins. These prion diseases are thought to be spread by
eating infected tissue, such as beef from a cow with mad cow disease.
Another method may be by contact with infected tissue through broken
skin or mucous membranes. Some people are at greater risk for prion
disease because of heredity. Specific risk factors for new variant CJD
are not known.
The recent outbreak of new variant CJD in the United Kingdom may have
been due to people eating beef from cows with mad cow disease. It is
possible, though not proven, that avoidance of eating meat may have
prevented this outbreak. How is this diagnosed? A final diagnosis can be
made with a biopsy of the brain. This involves taking a small piece of
brain tissue with a special needle. The piece of tissue can then be
examined with a microscope. At death, an autopsy will also show specific
changes in the brain.
The long-term effects of the disease to humans are brain
degeneration and death are the final results of mad cow disease. Though
Mad cow disease is not thought to be contagious. Exposure to the
internal organs of an animal with mad cow disease may transmit this
disease, but this has not been proven. It should be noted that this
disease is very poorly understood. There is much debate over whether or
not it can be passed to humans at all. People who are cannibals in
remote parts of the world have been shown to get other prion diseases
from eating infected people's brains.
There is no treatment for this disease. Some medications may be
useful to reduce symptoms, such as psychiatric or behavioral problems.
All medications have possible side effects. These may include allergic
reactions and stomach upset. Specific side effects depend on the drugs
used. Death usually occurs within 2 years of when symptoms start.
Symptoms and physical exam are followed to see if any new medicines
to treat symptoms may be needed.
Creutzfeldt-Jakob Disease
Creutzfeldt-Jakob disease (CJD) is a rare and fatal infectious disease
of the brain. It affects about one person in a million. Experts do not
know how most people get this disease, although sometimes CJD is
inherited and called familial CJD. CJD usually occurs in people who are
at least 60 years old. The disease is characterized by rapid progressive
dementia. Usually, the person dies within 6 months after symptoms
appear. The incubation period, which is the time between exposure to the
organism and development of symptoms, is thought to range between 3 and
20 years.
Symptoms include: dementia, as shown by confusion, disorientation, and
memory loss sight problems abnormal behavior movement abnormalities
muscle spasms.
Experts are not sure what causes CJD. The disease can be transmitted in
several ways. One is hormones used to treat certain
endocrine problems, such as hormone disorders, are originally taken from
an infected person and passed to the recipient. Another is donors
of certain human transplant tissues, such as corneas, are infected and
so the recipient gets infected. Third, the disease
is inherited from another family member. Forth, an
individual, such as a surgeon or healthcare worker, is exposed to
infected tissue, for example, while operating on an infected patient's
brain. This infection is then passed to other patients through contact
with the surgeon or healthcare worker.
The best way to diagnose CJD is to biopsy the brain by taking tissue and
examining it under a microscope. Sometimes brain imaging is helpful
using computerized tomography scan (CAT), a special three-dimensional
x-ray, or magnetic resonance imaging, a special three-dimensional image
using magnets, and an electroencephalogram (EEG),a recording of brain
waves.
CJD causes progressive mental deterioration that results in death in
about 6 months. CJD cannot be spread from person to person unless there
is contact with infected brain tissue and There are no treatments for
CJD!!!
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