Types Of PokéBalls
| Item | Effect | Cost | Location |
| Poke Ball | This ball catches Pokémon, but does not work on stronger Pokémon. | 200 | |
| Great Ball | This Pokéball perfoms better than the regular Pokéball at a slightly higher price. | 600 | |
| Ultra Ball | This ball works better than the Great Ball and costs significantly higher. | 1200 | |
| Safari Ball | A special type of Pokéball that are only to be used in the Safari Zone. | 500 for 30 | Safari Zone |
| Master Ball | This Pokéball is 1-of-a-kind and works 100% of the time on any Pokémon. Think long and hard on what Pokémon you want to use this on. | Priceless | Silph Co. |
Mystery Items
| Item | Effect | Cost | Location |
| Fire Stone | Evolves Vulpix, Growlithe, Eevee (3 different Fire Pokémon). | 2100 | Celadon Dept. Store |
| Thunder Stone | Evolves Pikachu, Eevee (2 different Electric Pokémon). | 2100 | Celadon Dept. Store |
| Water Stone | Evolves Staryu, Cloyster, Poliwhirl, Eevee (4 different Water Pokémon). | 2100 | Celadon Dept. Store |
| Leaf Stone | Evolves Gloom, Weepinbell, Exeggute (3 different Plant Pokémon). | 2100 | Celadon Dept. Store |
| Moon Stone | Evolves Jigglypuff, Clefairy, Nidorina, Nidorino (4 different pokémon). | find | |
| Helix Fossil | Old fossil of an extinct Pokémon. Can be used to duplicate the extinct Pokémon Omanyte. If you get this, you can't get the Dome Fossil. | find | Mt. Moon |
| Dome Fossil | Old fossil of an extinct Pokémon. Can be used to duplicate the extinct Pokémon Kabuto. If you get this, you can't get the Helix Fossil. | find | Mt. Moon |
| Old Amber | Old fossil of an extinct Pokémon. Can be used to duplicate the extinct Pokémon Aerodactyl. | find | Pewter City (museum) |
Recovery Items
| Item | Effect | Cost | Location |
| Antidote | Cures Poison. | 100 | |
| Burn Heal | Cures Burn. | 250 | |
| Ice Heal | Thaws out Frozen Pokémon. | 250 | |
| Awakening | Wakes up sleeping Pokémon. | 200 | |
| Paralyz Heal | Unparalyzes Pokémon. | 200 | |
| Full Heal | Heals any of the conditions that the items above will heal. | ||
| Potion | Heals 20 HP. | ||
| Super Potion | Heals 50 HP. | 700 | |
| Hyper Potion | Heals 200(?) HP. I asked my brother on this, so blame him if it's wrong! | find | |
| Max Potion | Heals ALL HP. | 3000 | |
| Full Restore | Heals all conditions and restores HP fully. | find | |
| Revive | Revives fainted Pokémon to 1/2 HP. | 1500 | |
| Max Revive | Revives fainted Pokémon to full HP. |
Pokémon Power-Ups
| Item | Effect | Cost | Location |
| Rare Candy | Increases a Pokémon's level by 1. | find | |
| HP UP | HP Increases a little. | 9800 | Celadon Dept. Store |
| Protein | Attack power increases a little. | 9800 | Celadon Dept. Store |
| Iron | Defense increases a little. | 9800 | Celadon Dept. Store |
| Carbos | Speed increases a little. | 9800 | Celadon Dept. Store |
| Calcium | Special Ability increases a little. | 9800 | Celadon Dept. Store |
| X Attack | Attack increases in battle. | 550 | Celadon Dept. Store |
| X Defend | Defense increases in battle. | 550 | Celadon Dept. Store |
| X Speed | Speed Increases in battle. | 350 | Celadon Dept. Store |
| X Special | Special increases in battle. | 350 | Celadon Dept. Store |
| Guard Spec. | In battle, enemy Pokémon can't use special attacks. | 700 | Celadon Dept. Store |
| Dire Hit | Attacks become more effective in battle. | 650 | Celadon Dept. Store |
| X Accuracy | Increases Accuracy during a battle. | 950 | Celadon Dept. Store |
| PP Up | PP level of an ability increases a little. | find |
Field Moving
| Item | Effect | Cost | Location |
| Bicycle | Allows you to move faster than walking. | 1,000,000 | Cerulean |
| Escape Rope | Pulls you out of caves (or certain buildings) instantly. (Like Dig) | 550 | |
| Repel | Repels weak Pokémon for a while. | ||
| Super Repel | Repels Pokémon longer than Repel. | 500 | |
| Max Repel | Repels Pokémon longer than Super Repel. |
Special Items
| Item | Effect | Cost | Location |
| Pokedex | A device that stores Pokémon information. | find | Pallet Town |
| Town Map | Helps you navigate in the world. | find | Pallet Town |
Miscellaneous
| Item | Effect | Cost | Location |
| Nugget | Sell this for 5000 at any store. | find | |
| Gold Teeth | Give this to the Safaro Zone Warden for an HM. | find | Safari Zone |
| S.S. Ticket | Given to you if you help bill. | Bill's Cottage | |
| Poke Doll | Give to the girl who immitates people in Saffron. It can help you escape out of battles too. | 1000 | Celadon Dept. Store |
| Silph Scope | Allows you to ID and catch ghosts in Pokémon Tower. | find | Game Corner Basement. |
| Poke Flute | Wakes up the Snorlax blocking the paths. Can also wake up sleeping Pokémon in battle. Very useful. | find | Pokémon Tower |
| Old Rod | Fish up Magikarp. | Vermillion City | |
| Good Rod | Fish up more water Pokémon. | Fuschia City | |
| Super Rod | Fish up more and better water Pokémon than the Good and Old Rod. | Route from Lavender to Fuschia | |
| Itemfinder | Tells you if there is a hidden item near you. | ||
| Exp. All | Divides EXP. among your Pokémon, but lowers it slightly. | Prof. Oak's aide | |
| Coin | Used to play the slot machines at Game Corner. Can be traded in for Prizes. | 1000 for 50 | Game Corner |
| Coin Case | It allows you to carry up to 9999 coins. | find | Celadon |
| Fresh Water | Restores HP a little. Give it to thirsty girl for a free TM. Give it to the guard at the City Gates to open all gates. | 200 | Celadon Dept. Store |
| Soda Pop | Restores HP a little. Give it to thirsty girl for a free TM. | 300 | Celadon Dept. Store |
| Lemonade | Restores HP a little. Give it to thirsty girl for a free TM. | 350 | Celadon Dept. Store |
