Bart Simpson: Met him while we was working at Fat Tony's Hideout, "The Local Businessmans Social Club" after school. This was Fat Tony's first appearance also, the episode was Bart the Murderer.
Homer Simpson: First met Homer, when he took a part-time job as Krusty the Klown. Fat Tony kidnapped him thinking he was the real Krust in Homie the Clown. Met for a second time in The Twisted World of Marge Simpson we the mobsters help limit the pretzel market as it were. And also in Papa's Got a Brand New Badge where Fat Tony and the New Jersey mafia went to gun down Homer.
Marge Simpson: First met her in The Twisted World of Marge Simpson where Fat Tony demanded money from Marge, 100% of the profits, for helping her out. They also met again in Papa's Got a Brand New Badge where she tried to stop Fat Tony and the New Jersey Mafia killing Homer.
Chief Clancy Wiggum: First time, in Fat Tony's first appearance, Bart the Murderer where we arrested the mobsters. Also in Mayored to the Mob wheree Wiggum arrested them again. For once Wiggum was doing his job proberly!
Krusty the Klown: He has hasd many run-ins with Fat Tony. Such as Homie the Clown, where the mobsters kidnapped Homer thining he was Krusty!
Kent Brockman: The only time Fat Tony spoke to Kent was in Mayored to the Mob where he did a news report live form the arresteing of Fat Tony. Kent asked what him was gonna do to the Mayor, and he sore his revenge.