Keel Lorenz is the most important people among 5 directors of SEELE and he is also the chairman of Human Instrumentality Program. He in charge all the things in NERV including the development of Magi System, Evangelions and Human Instrumentality Program. According to the Movies Series, his body is totally machine from backbone down.

SEELE is a secret organisation that existed even before the Second Impact. It hid the truth about the Second Impact and the existence of Angels and uses its power to abuse UN and other countries. After the Second Impact, it used UN as a cover, established the Committee of Human Complementation and the secret agency NERV, and also built the EVA series.