She and her husband lived in the city of Rome, and whereas her husband was one of the most important men in the city, she became one of the city's leading matrons. Though I am not precisely sure of the circumstances, her husband died while they were both still in Rome. In 410, as Alaric was approaching the city, Faltonia Anicia Proba, an unnamed daughter, and her grand-daughter, fled the city and made their way safely to Africa. The unnamed daughter may well have been her daughter-in-law, one Anicia Juliana (2) who was the wife of Faltonia Anicia Proba's son, Anicius Hermogenianus Olybrius. This is supported by the fact that the grand-daughter was the child of this union, Demetrias, and it has been reported that Anicius Hermogenianus Olybrius died trying to escape with his family from Rome in 410.
Anyway, Faltonia Anicia Proba had at least three sons, Anicius Hermogenianus Olybrius, Anicius Probinus, and the Unnamed gentleman #1. Of her ultimate fate, as of yet I have found nothing.