Due to a regressive genetic condition present in some human beings, the Queen and her followers share a connection to the earliest insects. Where Homo Erectus branched off, Homo Insectus did not.

Claiming that the time for her new breed has now arrived, the Queen attempted to take over a bank building in the Financial District, where she created a bizarre hive for her followers.

In Spectacular Spider-Man #16, Spider-Man was compelled towards his encounter with the Queen by a kind of animal magnetism she projected. While she could not control his thoughts, he found himself unable to stand against her telepathic powers, which seemed to control the insect aspect of his personality.

But the shocking truth was soon revealed: Soria intended to take Spider-Man as her mate, intrigued by his unique genetic makeup.

Spider-Man rejected this notion, and was saved from a lifetime of subservience only by the timely intervention of Captain America. During their final encounter, the Queen plunged over eighty floors to her supposed death.

But not before she had administered a fateful kiss.

ACT 1: Peter is hanging out in the Park with Mary Jane, who is angry at him about kissing the Queen. Peter tells her that there is absolutely nothing going on between the two of them but later that night, as he patrols the city as Spider-Man, he cannot shake the feeling that the kiss has stirred something inside him, something he has a terrible time getting out of his mind.

ACT 2: Elsewhere, Mary Jane is getting her hair done at the hair salon; the same hair salon where the Queen is coincidently getting a new haircut too. Her hair appointment over, the Queen makes her way into the subway tunnels, followed by a herd of mindless human drones. They soon reach an area of the tunnels where more mindless drones are occupied rebuilding the new hive.

ACT 3: S.H.I.E.L.D. Regional Headquarters. Emergency briefing. Captain America informs representatives from all branches of the U.S. Armed Forces as well as the CIA, NSA and even the British Intelligence Services that they must bring the Queen and Spider-Man to ground sometime within the next five or six days or they are going to have an extreme situation on their hands. Captain America stresses the issue by telling them that the Queen is more dangerous than a hundred Hulks, which renders everybody speechless.

ACT 4: Meanwhile, at Peter and Mary Jane's apartment, Peter is feeling under the weather and is having feverish nightmares about the Queen, as he sees himself with blood gushing out of his mouth and ears. As he awakens from this latest nightmare, he slowly makes his way into the kitchen where he grabs a can of soda and seems to struggle to open it.

ACT 5: Back at the hive, the Queen recounts the story of her life. She tells them how she used to be a member of the women's army auxiliary corps during the Second World War and that prevailing sentiment forbade her from entering combat. One day however, she was – to her surprise – drafted into a special unit of the marines, which was mostly made up of a bunch of rag tags whom, for the most part, had been unable to complete the basic rigors of specialized training. One day, they were all taken off base, out to the desert, where they were used as human guinea pigs and exposed to the atomic bomb. When she woke up from the experiment, she found herself inside a prison, strapped in a straight jacket. She felt desperately ill, as there were cockroaches on the floor, refusing to run away from her. One day, a man (Captain America) came to visit her and she fell in love with him. But he loved his country more than he did her. And he left her behind. Suddenly, the Queen interrupts her story when she receives – through telepathy – a message from one of her drones, which happens to be at the briefing with Captain America. He tells her of the latest development but the Queen worries not, as she knows that if they do find her, there is nothing they can do to stop her.

ACT 6: Mary Jane returns home with a spiffy new haircut and finds the apartment unlit with roaches crawling over the floor. She slowly makes her way into the kitchen where she finds Peter lying on the ground, hiding his face with his hands and telling MJ not to turn on the lights. Thinking that he is joking around, she turns it on. She stares in disbelief at Peter...he has grown an extra pair of eyes.