Lou pitching register -- All players in database
Regular season
| Primary |
| Name | Year | Team | P | Age | ERA | W | L | S | G | GS | CG | SHO | INN | H | R | ER | BB | K | HR | GDP | CERA | BF | RCERA |
| Roberto Hernandez | 1992 | TEX | rp | 27 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1.1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | 4 | 0.00 |
| Jose Mesa | 1995 | BAL | rp | 29 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 14.52 | 2 | 12.15 |
| Jack Pfiester* | 1906 | WAS | sp | 28 | 0.00 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 9.0 | 2 | 0 | 0 | 0 | 8 | 0 | 1 | 0.21 | 30 | 0.14 |
| Vicente Romo | 1968 | BAY | rp | 25 | 0.00 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 | 3 | 0.00 |
| Bob Howry | 2005 | JS | rp | 31 | 1.19 | 3 | 0 | 3 | 20 | 0 | 0 | 0 | 22.2 | 15 | 3 | 3 | 10 | 6 | 3 | 3 | 2.68 | 91 | 2.65 |
| Kasuhiro Sasaki | 2001 | BAY | rp | 33 | 1.31 | 1 | 0 | 1 | 13 | 0 | 0 | 0 | 20.2 | 14 | 3 | 3 | 5 | 15 | 3 | 1 | 2.10 | 80 | 2.36 |
| Tug McGraw* | 1980 | JS | rp | 35 | 1.80 | 5 | 3 | 2 | 53 | 1 | 0 | 0 | 80.0 | 55 | 16 | 16 | 23 | 51 | 4 | 7 | 1.96 | 308 | 1.95 |
| Dizzy Dean | 1938 | FLP | sp | 28 | 1.80 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 5.0 | 6 | 1 | 1 | 2 | 2 | 0 | 1 | 4.56 | 22 | 3.88 |
| Eric Gagne | 2003 | LH | cl | 27 | 2.11 | 4 | 3 | 36 | 59 | 0 | 0 | 0 | 72.2 | 64 | 19 | 17 | 19 | 78 | 2 | 13 | 2.59 | 282 | 2.22 |
| Billy Wagner* | 1999 | TEX | cl | 27 | 2.32 | 3 | 4 | 23 | 41 | 0 | 0 | 0 | 50.1 | 40 | 15 | 13 | 25 | 63 | 3 | 7 | 3.22 | 213 | 2.86 |
| Dave Righetti* | 1981 | HUD | rp | 22 | 2.35 | 2 | 0 | 1 | 3 | 2 | 0 | 0 | 15.1 | 15 | 5 | 4 | 10 | 8 | 1 | 1 | 4.64 | 70 | 4.27 |
| Brad Lidge | 2004 | NYM | cl | 27 | 2.44 | 6 | 2 | 24 | 42 | 0 | 0 | 0 | 55.1 | 50 | 15 | 15 | 21 | 63 | 3 | 12 | 3.33 | 219 | 2.85 |
| John Wetteland | 1993 | MIC | rp | 26 | 2.49 | 9 | 5 | 7 | 59 | 0 | 0 | 0 | 90.1 | 72 | 28 | 25 | 34 | 90 | 6 | 6 | 2.67 | 369 | 2.85 |
| Gabe White* | 2000 | HUD | cl | 28 | 2.53 | 4 | 4 | 34 | 72 | 0 | 0 | 0 | 117.1 | 96 | 36 | 33 | 28 | 60 | 9 | 11 | 2.52 | 476 | 2.74 |
| Denny McLain | 1968 | MIC | sp | 24 | 2.55 | 2 | 0 | 0 | 3 | 3 | 1 | 0 | 17.2 | 16 | 5 | 5 | 10 | 13 | 1 | 3 | 4.02 | 75 | 3.32 |
| Jeff Gray | 1991 | HUD | rp | 28 | 2.56 | 11 | 9 | 3 | 60 | 0 | 0 | 0 | 98.1 | 73 | 32 | 28 | 24 | 45 | 12 | 13 | 2.36 | 383 | 2.52 |
| Kent Tekulve | 1983 | VAN | cl | 36 | 2.62 | 6 | 4 | 32 | 50 | 0 | 0 | 0 | 79.0 | 61 | 25 | 23 | 35 | 13 | 3 | 8 | 2.68 | 331 | 2.49 |
| Tom Gordon | 2004 | FLP | rp | 36 | 2.64 | 6 | 4 | 1 | 54 | 0 | 0 | 0 | 61.1 | 56 | 21 | 18 | 24 | 50 | 7 | 3 | 3.62 | 260 | 3.97 |
| Rafael Soriano | 2003 | JS | rp | 23 | 2.65 | 2 | 6 | 1 | 40 | 0 | 0 | 0 | 51.0 | 51 | 22 | 15 | 14 | 60 | 5 | 1 | 3.48 | 222 | 3.95 |
| Dale Murray | 1974 | MIC | rp | 24 | 2.71 | 9 | 0 | 0 | 67 | 0 | 0 | 0 | 149.2 | 113 | 50 | 45 | 77 | 51 | 14 | 17 | 3.26 | 619 | 3.05 |
| Doug Brocail | 1998 | MIC | rp | 31 | 2.75 | 5 | 0 | 2 | 30 | 0 | 0 | 0 | 59.0 | 65 | 22 | 18 | 22 | 35 | 2 | 6 | 4.15 | 262 | 4.32 |
| Mike Jackson | 1998 | LH | rp | 33 | 2.78 | 4 | 1 | 2 | 30 | 0 | 0 | 0 | 58.1 | 49 | 19 | 18 | 14 | 27 | 6 | 6 | 2.91 | 230 | 3.07 |
| Tom Niedenfuer | 1985 | MOT | rp | 25 | 2.84 | 0 | 0 | 3 | 19 | 0 | 0 | 0 | 25.1 | 26 | 9 | 8 | 9 | 24 | 3 | 1 | 4.12 | 110 | 4.34 |
| Hank Aguirre* | 1962 | FLP | sp | 31 | 2.94 | 17 | 6 | 0 | 35 | 35 | 6 | 2 | 229.1 | 170 | 89 | 75 | 84 | 118 | 22 | 16 | 2.68 | 941 | 2.91 |
| Paul Wilson | 2000 | CRB | sp | 27 | 2.96 | 4 | 5 | 0 | 43 | 0 | 0 | 0 | 54.2 | 50 | 21 | 18 | 22 | 30 | 2 | 2 | 3.53 | 243 | 3.36 |
| Christy Mathewson | 1905 | BAL | sp | 24 | 2.99 | 18 | 12 | 0 | 35 | 35 | 12 | 6 | 250.0 | 215 | 89 | 83 | 86 | 151 | 22 | 20 | 3.10 | 1031 | 3.06 |
| Jeff Russell | 1989 | CRB | rp | 27 | 3.00 | 3 | 1 | 0 | 28 | 0 | 0 | 0 | 54.0 | 39 | 21 | 18 | 24 | 46 | 4 | 4 | 2.68 | 220 | 2.96 |
| Dave McNally* | 1968 | TEX | sp | 25 | 3.03 | 1 | 1 | 2 | 20 | 0 | 0 | 0 | 32.2 | 28 | 11 | 11 | 10 | 19 | 3 | 2 | 3.26 | 134 | 3.64 |
| Dan Quisenberry | 1983 | TEX | rp | 30 | 3.09 | 12 | 4 | 3 | 55 | 0 | 0 | 0 | 93.1 | 86 | 34 | 32 | 24 | 27 | 9 | 5 | 3.08 | 387 | 3.13 |
| Steve Ontiveros | 1985 | MIC | rp | 24 | 3.13 | 1 | 3 | 0 | 14 | 0 | 0 | 0 | 31.2 | 23 | 15 | 11 | 14 | 2 | 4 | 1 | 3.09 | 135 | 3.36 |
| Johnny Miljus | 1927 | MOT | rp | 32 | 3.13 | 6 | 9 | 2 | 56 | 0 | 0 | 0 | 83.1 | 80 | 35 | 29 | 29 | 37 | 7 | 7 | 3.53 | 353 | 3.49 |
| Joe Nathan | 2004 | NYM | rp | 29 | 3.13 | 4 | 1 | 1 | 23 | 0 | 0 | 0 | 37.1 | 35 | 15 | 13 | 14 | 39 | 3 | 3 | 3.60 | 154 | 3.07 |
| Joel Pineiro | 2001 | TEX | sp | 22 | 3.14 | 5 | 0 | 1 | 39 | 0 | 0 | 0 | 66.0 | 51 | 23 | 23 | 26 | 37 | 5 | 9 | 2.79 | 268 | 2.71 |
| Jeff Montgomery | 1989 | COB | rp | 27 | 3.20 | 2 | 0 | 0 | 18 | 0 | 0 | 0 | 25.1 | 22 | 9 | 9 | 8 | 17 | 4 | 2 | 3.42 | 104 | 3.49 |
| Pat Jarvis | 1966 | FLP | sp | 25 | 3.20 | 7 | 1 | 0 | 48 | 0 | 0 | 0 | 90.0 | 85 | 44 | 32 | 13 | 43 | 7 | 5 | 2.71 | 372 | 3.03 |
| Steve Reed | 1995 | WAS | cl | 29 | 3.21 | 5 | 4 | 21 | 46 | 0 | 0 | 0 | 73.0 | 77 | 27 | 26 | 32 | 35 | 5 | 8 | 4.45 | 320 | 4.39 |
| Les Lancaster | 1989 | MAN | rp | 27 | 3.24 | 4 | 2 | 1 | 31 | 0 | 0 | 0 | 72.1 | 73 | 31 | 26 | 25 | 38 | 6 | 6 | 3.87 | 303 | 3.83 |
| Dennis Eckersley | 1990 | JS | cl | 35 | 3.24 | 5 | 4 | 32 | 58 | 1 | 0 | 0 | 100.0 | 93 | 37 | 36 | 17 | 74 | 12 | 15 | 3.28 | 399 | 3.19 |
| Ted Lyons | 1939 | TEX | sp | 38 | 3.25 | 13 | 11 | 0 | 33 | 33 | 12 | 4 | 238.1 | 229 | 99 | 86 | 54 | 111 | 26 | 23 | 3.28 | 979 | 3.43 |
| Lindy McDaniel | 1960 | HUD | rp | 24 | 3.26 | 7 | 0 | 2 | 24 | 8 | 2 | 0 | 85.2 | 77 | 38 | 31 | 20 | 78 | 9 | 7 | 2.94 | 352 | 3.17 |
| Dave Smith | 1987 | FLP | cl | 32 | 3.27 | 2 | 6 | 28 | 48 | 0 | 0 | 0 | 55.0 | 45 | 23 | 20 | 23 | 54 | 7 | 8 | 3.56 | 231 | 3.40 |
| Mike Williams | 1998 | LH | rp | 29 | 3.27 | 4 | 3 | 0 | 21 | 0 | 0 | 0 | 33.0 | 28 | 13 | 12 | 15 | 30 | 2 | 3 | 3.29 | 139 | 3.28 |
| Ted Abernathy* | 1967 | CRB | cl | 45 | 3.28 | 5 | 4 | 35 | 69 | 0 | 0 | 0 | 112.2 | 89 | 51 | 41 | 44 | 73 | 12 | 14 | 3.11 | 471 | 3.03 |
| Randy Johnson* | 2004 | TEX | sp | 40 | 3.35 | 16 | 14 | 0 | 35 | 35 | 17 | 3 | 265.2 | 248 | 109 | 99 | 81 | 195 | 28 | 32 | 3.65 | 1099 | 3.53 |
| Rod Beck | 1993 | COB | rp | 24 | 3.43 | 2 | 1 | 0 | 47 | 0 | 0 | 0 | 97.0 | 97 | 38 | 37 | 32 | 82 | 9 | 9 | 3.99 | 417 | 4.08 |
| Rich Gossage | 1981 | VAN | rp | 29 | 3.45 | 7 | 2 | 0 | 41 | 0 | 0 | 0 | 91.1 | 65 | 39 | 35 | 43 | 89 | 9 | 12 | 2.93 | 372 | 2.85 |
| Jim Brewer* | 1972 | COB | rp | 34 | 3.47 | 4 | 0 | 0 | 16 | 0 | 0 | 0 | 23.1 | 21 | 9 | 9 | 13 | 17 | 4 | 3 | 4.70 | 101 | 4.74 |
| Ed Reulbach | 1905 | BAY | sp | 22 | 3.47 | 9 | 8 | 0 | 26 | 26 | 6 | 0 | 184.0 | 164 | 86 | 71 | 72 | 113 | 18 | 19 | 3.71 | 777 | 3.68 |
| Mark Eichhorn | 1991 | FLP | rp | 30 | 3.48 | 1 | 1 | 2 | 22 | 0 | 0 | 0 | 31.0 | 31 | 13 | 12 | 10 | 18 | 2 | 4 | 3.93 | 133 | 3.94 |
| Houston Street | 2005 | BAY | rp | 42 | 3.50 | 6 | 1 | 0 | 31 | 0 | 0 | 0 | 64.1 | 65 | 29 | 25 | 30 | 52 | 6 | 3 | 4.40 | 280 | 4.21 |
| Pedro Martinez | 2000 | LH | sp | 28 | 3.55 | 15 | 10 | 0 | 32 | 32 | 9 | 2 | 236.0 | 192 | 107 | 93 | 48 | 211 | 31 | 18 | 2.80 | 958 | 2.95 |
| Darren Holmes | 1995 | NYM | rp | 29 | 3.58 | 1 | 0 | 0 | 34 | 0 | 0 | 0 | 60.1 | 59 | 25 | 24 | 34 | 38 | 3 | 6 | 4.19 | 266 | 4.07 |
| Joe Sambito* | 1980 | VAN | rp | 28 | 3.60 | 5 | 7 | 1 | 46 | 0 | 0 | 0 | 50.0 | 56 | 23 | 20 | 6 | 29 | 8 | 4 | 3.99 | 210 | 4.26 |
| Jose Valverde | 2003 | WAS | rp | 23 | 3.63 | 3 | 2 | 1 | 53 | 0 | 0 | 0 | 89.1 | 72 | 41 | 36 | 60 | 88 | 12 | 13 | 4.31 | 394 | 3.93 |
| Arthur Lee Rhodes* | 2001 | MAN | rp | 31 | 3.64 | 10 | 6 | 0 | 80 | 0 | 0 | 0 | 113.2 | 102 | 48 | 46 | 56 | 107 | 7 | 11 | 3.71 | 487 | 3.41 |
| Bobby Thigpen | 1990 | CRB | rp | 26 | 3.65 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 12.1 | 13 | 7 | 5 | 9 | 7 | 1 | 2 | 5.53 | 58 | 4.62 |
| Smokey Joe Williams | 1912 | VAN | sp | 27 | 3.66 | 3 | 0 | 0 | 21 | 0 | 0 | 0 | 51.2 | 56 | 24 | 21 | 16 | 42 | 4 | 6 | 4.19 | 219 | 3.80 |
| Jeff Zimmerman | 1999 | MAN | rp | 26 | 3.67 | 12 | 2 | 1 | 67 | 0 | 0 | 0 | 125.0 | 111 | 61 | 51 | 50 | 61 | 21 | 9 | 4.16 | 530 | 3.97 |
| Keith Foulke | 1999 | HUD | rp | 26 | 3.68 | 10 | 1 | 1 | 44 | 0 | 0 | 0 | 124.2 | 118 | 60 | 51 | 31 | 119 | 21 | 10 | 3.83 | 517 | 3.89 |
| Rob Murphy* | 1986 | MIC | cl | 26 | 3.70 | 6 | 11 | 25 | 62 | 0 | 0 | 0 | 99.2 | 76 | 47 | 41 | 50 | 49 | 9 | 11 | 3.20 | 421 | 3.20 |
| Addie Joss | 1908 | MAN | sp | 28 | 3.71 | 15 | 9 | 0 | 37 | 37 | 11 | 4 | 254.2 | 262 | 112 | 105 | 60 | 128 | 37 | 13 | 3.88 | 1071 | 4.08 |
| Willie Mitchell* | 1913 | NYM | sp | 23 | 3.72 | 3 | 5 | 0 | 27 | 14 | 1 | 0 | 111.1 | 99 | 55 | 46 | 53 | 68 | 18 | 8 | 4.25 | 483 | 4.31 |
| Jimmy Key* | 1987 | VAN | sp | 26 | 3.72 | 2 | 0 | 1 | 22 | 3 | 1 | 0 | 65.1 | 64 | 30 | 27 | 18 | 32 | 7 | 9 | 3.54 | 272 | 3.72 |
| Rollie Fingers | 1981 | BAL | rp | 34 | 3.74 | 4 | 4 | 0 | 33 | 0 | 0 | 0 | 67.1 | 62 | 41 | 28 | 20 | 52 | 8 | 3 | 3.33 | 285 | 3.64 |
| Todd Frohwirth | 1991 | WAS | rp | 28 | 3.76 | 1 | 1 | 1 | 29 | 0 | 0 | 0 | 67.0 | 71 | 31 | 28 | 37 | 32 | 4 | 14 | 4.87 | 296 | 4.33 |
| Tim Burke | 1987 | LH | rp | 28 | 3.76 | 6 | 4 | 2 | 66 | 0 | 0 | 0 | 136.1 | 131 | 63 | 57 | 41 | 58 | 14 | 13 | 3.75 | 580 | 3.84 |
| Dick Hall | 1964 | NYM | rp | 33 | 3.77 | 5 | 2 | 0 | 63 | 1 | 0 | 0 | 174.1 | 167 | 74 | 73 | 50 | 70 | 26 | 13 | 3.73 | 725 | 3.87 |
| Grant Jackson* | 1976 | LH | rp | 33 | 3.80 | 2 | 1 | 0 | 30 | 0 | 0 | 0 | 66.1 | 64 | 34 | 28 | 39 | 23 | 6 | 5 | 4.57 | 297 | 4.41 |
| Bob Feller | 1940 | NYM | sp | 21 | 3.80 | 8 | 9 | 0 | 22 | 22 | 6 | 2 | 132.2 | 123 | 68 | 56 | 62 | 111 | 13 | 15 | 4.05 | 564 | 3.80 |
| Jack Chesbro | 1904 | VAN | sp | 30 | 3.82 | 15 | 10 | 0 | 33 | 33 | 12 | 1 | 242.2 | 239 | 115 | 103 | 87 | 146 | 26 | 23 | 3.92 | 1035 | 3.88 |
| Ben Sheets | 2004 | LH | sp | 25 | 3.82 | 8 | 9 | 0 | 25 | 25 | 4 | 0 | 146.0 | 159 | 74 | 62 | 46 | 108 | 21 | 8 | 4.55 | 637 | 4.74 |
| Bruce Sutter | 1977 | BAY | cl | 24 | 3.87 | 8 | 8 | 22 | 60 | 0 | 0 | 0 | 93.0 | 90 | 47 | 40 | 45 | 94 | 6 | 8 | 3.93 | 410 | 4.10 |
| Troy Percival | 1995 | LH | rp | 25 | 3.89 | 9 | 7 | 2 | 65 | 0 | 0 | 0 | 78.2 | 78 | 37 | 34 | 38 | 75 | 11 | 4 | 4.74 | 343 | 4.83 |
| Pascual Perez | 1987 | JS | sp | 30 | 3.89 | 5 | 3 | 0 | 37 | 3 | 0 | 0 | 106.1 | 104 | 52 | 46 | 27 | 66 | 16 | 8 | 3.83 | 448 | 3.97 |
| John Hiller* | 1973 | FLP | rp | 30 | 3.93 | 0 | 1 | 1 | 26 | 0 | 0 | 0 | 36.2 | 36 | 19 | 16 | 16 | 27 | 5 | 5 | 4.66 | 163 | 4.59 |
| Jesse Tannehill* | 1902 | STL | sp | 27 | 3.96 | 18 | 6 | 0 | 34 | 34 | 8 | 2 | 227.1 | 237 | 115 | 100 | 55 | 138 | 36 | 26 | 4.28 | 965 | 4.06 |
| Joe Wood | 1912 | MIC | sp | 22 | 3.96 | 11 | 12 | 0 | 32 | 32 | 9 | 2 | 218.0 | 228 | 108 | 96 | 70 | 166 | 29 | 17 | 4.39 | 937 | 4.39 |
| Al Orth | 1901 | TEX | sp | 28 | 3.97 | 12 | 13 | 0 | 31 | 31 | 13 | 0 | 201.2 | 190 | 102 | 89 | 56 | 73 | 26 | 12 | 3.55 | 850 | 3.81 |
| Al Grabowski* | 1929 | FLP | rp | 27 | 3.99 | 8 | 5 | 2 | 57 | 0 | 0 | 0 | 70.0 | 77 | 36 | 31 | 16 | 40 | 11 | 4 | 4.41 | 301 | 4.86 |
| Harry Brecheen* | 1948 | MOT | sp | 33 | 4.00 | 15 | 10 | 0 | 35 | 35 | 11 | 2 | 232.0 | 237 | 116 | 103 | 67 | 158 | 27 | 12 | 3.91 | 1005 | 4.09 |
| Greg Maddux | 1995 | JS | sp | 29 | 4.00 | 15 | 10 | 0 | 30 | 30 | 10 | 2 | 211.2 | 231 | 101 | 94 | 50 | 120 | 16 | 20 | 3.92 | 895 | 3.90 |
| Duane Ward | 1991 | MOT | rp | 27 | 4.04 | 10 | 8 | 1 | 67 | 0 | 0 | 0 | 156.0 | 180 | 76 | 70 | 58 | 151 | 14 | 18 | 4.89 | 692 | 4.65 |
| Jason Isringhausen | 2002 | MAN | cl | 29 | 4.09 | 4 | 9 | 18 | 60 | 0 | 0 | 0 | 72.2 | 72 | 38 | 33 | 43 | 48 | 3 | 10 | 4.18 | 329 | 3.87 |
| Steve Mingori* | 1971 | CRB | rp | 27 | 4.09 | 10 | 6 | 0 | 72 | 0 | 0 | 0 | 81.1 | 84 | 46 | 37 | 38 | 51 | 11 | 4 | 4.89 | 362 | 5.13 |
| Armando Benitez | 1999 | COB | rp | 26 | 4.10 | 3 | 5 | 2 | 35 | 0 | 0 | 0 | 52.2 | 53 | 24 | 24 | 27 | 67 | 9 | 7 | 5.21 | 227 | 4.86 |
| Doug Jones | 1997 | STL | cl | 40 | 4.10 | 4 | 9 | 31 | 57 | 0 | 0 | 0 | 68.0 | 85 | 39 | 31 | 22 | 59 | 9 | 6 | 5.46 | 306 | 5.79 |
| John Smoltz | 1996 | MAN | sp | 29 | 4.10 | 8 | 8 | 0 | 32 | 32 | 5 | 0 | 182.0 | 194 | 93 | 83 | 38 | 130 | 26 | 15 | 4.07 | 766 | 4.28 |
| Zane Smith* | 1990 | MIC | sp | 29 | 4.12 | 0 | 0 | 0 | 21 | 0 | 0 | 0 | 43.2 | 39 | 21 | 20 | 20 | 29 | 8 | 7 | 4.38 | 183 | 4.10 |
| Babe Adams | 1919 | BAY | sp | 37 | 4.14 | 11 | 8 | 0 | 28 | 27 | 9 | 1 | 187.0 | 200 | 91 | 86 | 33 | 92 | 23 | 11 | 3.72 | 778 | 3.93 |
| Mort Cooper | 1942 | FLP | sp | 29 | 4.14 | 17 | 11 | 0 | 35 | 35 | 5 | 1 | 223.2 | 232 | 115 | 103 | 55 | 129 | 27 | 19 | 3.90 | 950 | 4.03 |
| Jack Quinn | 1918 | WAS | sp | 34 | 4.15 | 11 | 10 | 1 | 68 | 0 | 0 | 0 | 97.2 | 110 | 49 | 45 | 15 | 54 | 15 | 17 | 4.26 | 401 | 4.15 |
| Jose Jimenez | 2000 | STL | rp | 26 | 4.15 | 2 | 2 | 1 | 37 | 0 | 0 | 0 | 73.2 | 67 | 36 | 34 | 26 | 20 | 9 | 6 | 3.77 | 306 | 3.56 |
| Van Mungo | 1937 | CRB | sp | 26 | 4.18 | 12 | 15 | 0 | 32 | 32 | 9 | 0 | 206.2 | 204 | 121 | 96 | 76 | 171 | 27 | 19 | 4.13 | 898 | 4.23 |
| Curt Leskanic | 1995 | STL | rp | 27 | 4.19 | 8 | 1 | 1 | 72 | 0 | 0 | 0 | 131.0 | 144 | 66 | 61 | 62 | 84 | 9 | 14 | 4.74 | 579 | 4.56 |
| Bobby Ayala | 1994 | MOT | rp | 24 | 4.20 | 3 | 2 | 0 | 28 | 0 | 0 | 0 | 49.1 | 41 | 30 | 23 | 30 | 42 | 2 | 6 | 3.56 | 212 | 3.45 |
| Francisco Rodriguez | 2004 | NYM | rp | 22 | 4.24 | 8 | 4 | 3 | 57 | 0 | 0 | 0 | 80.2 | 81 | 43 | 38 | 54 | 93 | 8 | 11 | 5.22 | 364 | 4.70 |
| Dwight Gooden | 1985 | VAN | sp | 20 | 4.26 | 16 | 6 | 0 | 32 | 32 | 7 | 1 | 205.0 | 221 | 104 | 97 | 77 | 147 | 17 | 17 | 4.38 | 899 | 4.44 |
| Walter Johnson | 1912 | HUD | sp | 24 | 4.27 | 13 | 10 | 0 | 35 | 35 | 11 | 1 | 246.1 | 259 | 133 | 117 | 66 | 195 | 37 | 14 | 4.26 | 1055 | 4.46 |
| J.R. Richard | 1980 | LH | sp | 30 | 4.28 | 16 | 7 | 0 | 33 | 33 | 3 | 0 | 193.1 | 175 | 98 | 92 | 96 | 159 | 32 | 25 | 4.63 | 817 | 4.22 |
| Ken Sanders | 1970 | BAY | rp | 28 | 4.32 | 4 | 6 | 1 | 71 | 0 | 0 | 0 | 139.2 | 144 | 76 | 67 | 59 | 73 | 7 | 19 | 4.11 | 618 | 4.09 |
| Trevor Hoffman | 1998 | VAN | rp | 30 | 4.32 | 0 | 0 | 1 | 17 | 0 | 0 | 0 | 25.0 | 32 | 13 | 12 | 10 | 21 | 1 | 4 | 5.25 | 114 | 4.77 |
| Tim Keefe | 1886 | LH | sp | 29 | 4.33 | 8 | 5 | 0 | 24 | 21 | 5 | 0 | 137.1 | 130 | 74 | 66 | 77 | 72 | 14 | 17 | 4.43 | 603 | 4.25 |
| Juan Marichal | 1965 | VAN | sp | 27 | 4.33 | 15 | 9 | 0 | 33 | 33 | 11 | 1 | 235.0 | 244 | 119 | 113 | 65 | 146 | 28 | 19 | 4.08 | 998 | 4.21 |
| Monty Stratton | 1937 | WAS | sp | 25 | 4.34 | 9 | 17 | 0 | 32 | 32 | 6 | 0 | 201.1 | 223 | 119 | 97 | 69 | 102 | 27 | 24 | 4.89 | 889 | 4.77 |
| Jesse Orosco* | 1989 | BAL | rp | 32 | 4.34 | 2 | 0 | 0 | 15 | 0 | 0 | 0 | 29.0 | 22 | 14 | 14 | 10 | 22 | 7 | 2 | 3.52 | 115 | 3.55 |
| Pud Galvin | 1885 | TEX | sp | 28 | 4.35 | 0 | 4 | 0 | 19 | 8 | 1 | 0 | 80.2 | 94 | 41 | 39 | 25 | 34 | 7 | 7 | 4.62 | 349 | 4.35 |
| Derek Lowe | 2002 | HUD | sp | 29 | 4.37 | 12 | 11 | 0 | 31 | 31 | 5 | 0 | 197.2 | 190 | 102 | 96 | 62 | 70 | 18 | 17 | 3.72 | 843 | 3.76 |
| B.J. Ryan* | 2004 | COB | rp | 28 | 4.37 | 7 | 7 | 0 | 38 | 0 | 0 | 0 | 35.0 | 34 | 18 | 17 | 12 | 38 | 6 | 3 | 4.18 | 148 | 4.34 |
| Rheal Cormier* | 2003 | JS | rp | 36 | 4.37 | 5 | 5 | 0 | 39 | 2 | 0 | 0 | 82.1 | 79 | 44 | 40 | 32 | 51 | 11 | 6 | 4.05 | 349 | 4.07 |
| Tom Henke | 1987 | CRB | rp | 29 | 4.37 | 7 | 1 | 1 | 54 | 0 | 0 | 0 | 107.0 | 114 | 60 | 52 | 39 | 123 | 15 | 10 | 4.59 | 478 | 4.57 |
| Mariano Rivera | 2005 | MAN | rp | 35 | 4.41 | 5 | 8 | 11 | 69 | 0 | 0 | 0 | 100.0 | 116 | 57 | 49 | 33 | 70 | 12 | 6 | 4.94 | 444 | 4.98 |
| Kevin Appier | 1993 | CRB | sp | 25 | 4.41 | 12 | 13 | 0 | 34 | 34 | 4 | 0 | 208.0 | 216 | 128 | 102 | 97 | 108 | 22 | 28 | 4.59 | 931 | 4.58 |
| Bob Ojeda* | 1988 | TEX | sp | 30 | 4.44 | 13 | 11 | 0 | 33 | 33 | 4 | 1 | 208.2 | 240 | 123 | 103 | 55 | 92 | 26 | 16 | 4.73 | 910 | 4.74 |
| Johan Santana* | 2004 | HUD | sp | 25 | 4.47 | 13 | 9 | 0 | 32 | 32 | 2 | 0 | 191.1 | 189 | 115 | 95 | 67 | 163 | 40 | 14 | 4.66 | 819 | 4.65 |
| Fred Toney | 1915 | BAY | sp | 26 | 4.48 | 4 | 5 | 0 | 26 | 12 | 4 | 1 | 88.1 | 80 | 56 | 44 | 48 | 53 | 15 | 9 | 4.61 | 390 | 4.69 |
| Pete Alexander | 1915 | FLP | sp | 28 | 4.49 | 17 | 14 | 0 | 42 | 42 | 6 | 1 | 262.2 | 270 | 148 | 131 | 79 | 166 | 34 | 21 | 4.06 | 1119 | 4.13 |
| Russ Ford | 1910 | STL | sp | 27 | 4.50 | 2 | 1 | 0 | 23 | 0 | 0 | 0 | 46.0 | 41 | 26 | 23 | 23 | 30 | 6 | 6 | 4.20 | 196 | 4.19 |
| Ray King* | 2004 | VAN | rp | 30 | 4.50 | 1 | 0 | 1 | 8 | 0 | 0 | 0 | 8.0 | 11 | 4 | 4 | 6 | 5 | 0 | 0 | 6.74 | 41 | 5.69 |
| Bill Bernhard | 1902 | FLP | sp | 31 | 4.53 | 2 | 2 | 1 | 23 | 0 | 0 | 0 | 53.2 | 45 | 28 | 27 | 12 | 22 | 10 | 3 | 3.08 | 219 | 3.26 |
| Hoyt Wilhelm | 1965 | BAL | cl | 41 | 4.54 | 4 | 4 | 24 | 58 | 0 | 0 | 0 | 81.1 | 91 | 46 | 41 | 28 | 42 | 13 | 6 | 4.90 | 367 | 5.06 |
| Kevin Millwood | 1999 | COB | sp | 24 | 4.56 | 10 | 6 | 0 | 28 | 28 | 2 | 1 | 179.2 | 168 | 100 | 91 | 69 | 111 | 28 | 18 | 4.17 | 771 | 4.21 |
| Cy Young | 1901 | FLP | sp | 34 | 4.56 | 14 | 15 | 0 | 42 | 42 | 13 | 2 | 256.2 | 298 | 141 | 130 | 66 | 149 | 37 | 24 | 4.83 | 1105 | 4.67 |
| Bret Saberhagen | 1989 | COB | sp | 25 | 4.64 | 15 | 16 | 0 | 33 | 33 | 13 | 1 | 233.0 | 263 | 144 | 120 | 67 | 136 | 43 | 24 | 5.06 | 1014 | 4.90 |
| Warren Hacker | 1952 | STL | sp | 27 | 4.64 | 5 | 1 | 0 | 10 | 10 | 3 | 1 | 64.0 | 59 | 38 | 33 | 15 | 26 | 10 | 6 | 3.39 | 260 | 3.42 |
| Bill Risley | 1994 | WAS | rp | 27 | 4.64 | 0 | 0 | 1 | 9 | 0 | 0 | 0 | 21.1 | 19 | 12 | 11 | 7 | 18 | 5 | 2 | 3.99 | 90 | 4.49 |
| Cy Blanton | 1935 | STL | sp | 26 | 4.65 | 13 | 13 | 0 | 34 | 34 | 8 | 0 | 224.1 | 256 | 130 | 116 | 71 | 132 | 32 | 26 | 4.96 | 980 | 4.81 |
| Octavio Dotel | 2002 | STL | rp | 28 | 4.66 | 10 | 9 | 3 | 72 | 0 | 0 | 0 | 96.2 | 88 | 59 | 50 | 57 | 101 | 18 | 13 | 4.99 | 431 | 4.41 |
| John Tudor* | 1985 | COB | sp | 31 | 4.66 | 5 | 14 | 0 | 32 | 32 | 6 | 0 | 210.1 | 253 | 123 | 109 | 62 | 97 | 36 | 18 | 5.43 | 922 | 4.92 |
| Jason Schmidt | 2003 | LH | sp | 30 | 4.67 | 6 | 12 | 0 | 23 | 23 | 4 | 0 | 129.0 | 131 | 81 | 67 | 48 | 72 | 15 | 14 | 4.25 | 555 | 4.33 |
| Nolan Ryan | 1991 | CRB | sp | 44 | 4.71 | 9 | 4 | 0 | 24 | 24 | 0 | 0 | 133.2 | 129 | 78 | 70 | 91 | 120 | 25 | 16 | 5.69 | 618 | 5.01 |
| Tommy Bond | 1878 | WAS | sp | 22 | 4.80 | 9 | 11 | 0 | 24 | 24 | 3 | 0 | 150.0 | 196 | 101 | 80 | 60 | 60 | 13 | 30 | 5.86 | 687 | 5.17 |
| Tom Glavine* | 1998 | MAN | sp | 32 | 4.81 | 10 | 9 | 0 | 38 | 38 | 1 | 0 | 189.0 | 204 | 110 | 101 | 87 | 79 | 22 | 25 | 5.12 | 839 | 4.90 |
| Don Sutton | 1972 | TEX | sp | 27 | 4.82 | 5 | 8 | 0 | 21 | 21 | 4 | 0 | 136.1 | 146 | 76 | 73 | 49 | 76 | 22 | 15 | 5.09 | 582 | 4.82 |
| Eddie Plank* | 1915 | WAS | sp | 39 | 4.89 | 8 | 11 | 0 | 29 | 29 | 7 | 2 | 158.1 | 182 | 96 | 86 | 47 | 90 | 26 | 18 | 5.07 | 686 | 5.22 |
| Ron Guidry* | 1978 | BAL | sp | 27 | 4.89 | 6 | 15 | 0 | 31 | 31 | 2 | 1 | 180.1 | 186 | 107 | 98 | 74 | 151 | 21 | 18 | 4.53 | 781 | 4.48 |
| Roger Clemens | 1997 | CRB | sp | 34 | 4.91 | 9 | 11 | 0 | 33 | 33 | 2 | 0 | 192.1 | 240 | 133 | 105 | 82 | 154 | 18 | 16 | 5.65 | 897 | 5.58 |
| Teddy Higuera* | 1988 | HUD | sp | 29 | 4.91 | 10 | 9 | 0 | 27 | 27 | 4 | 1 | 170.1 | 179 | 96 | 93 | 53 | 110 | 24 | 18 | 4.45 | 728 | 4.41 |
| Bob Gibson | 1968 | BAL | sp | 32 | 4.94 | 9 | 17 | 0 | 31 | 31 | 8 | 1 | 186.0 | 208 | 117 | 102 | 69 | 129 | 34 | 16 | 5.29 | 829 | 5.11 |
| Bill Henry* | 1964 | NYM | rp | 36 | 4.95 | 5 | 10 | 1 | 58 | 2 | 0 | 0 | 91.0 | 90 | 54 | 50 | 40 | 38 | 15 | 3 | 4.85 | 407 | 4.96 |
| Warren Spahn* | 1953 | BAL | sp | 32 | 4.96 | 8 | 8 | 0 | 25 | 25 | 2 | 0 | 139.2 | 153 | 87 | 77 | 60 | 74 | 17 | 10 | 4.94 | 626 | 5.05 |
| Cliff Melton* | 1937 | HUD | sp | 25 | 4.99 | 7 | 6 | 1 | 36 | 19 | 3 | 1 | 137.0 | 177 | 86 | 76 | 43 | 60 | 14 | 20 | 5.50 | 624 | 5.12 |
| Nick Maddox | 1907 | BAY | sp | 20 | 5.01 | 8 | 4 | 2 | 55 | 1 | 0 | 0 | 79.0 | 84 | 48 | 44 | 41 | 67 | 5 | 6 | 5.01 | 363 | 5.36 |
| Rube Vickers | 1908 | BAY | sp | 30 | 5.02 | 11 | 10 | 0 | 31 | 31 | 8 | 0 | 197.1 | 219 | 119 | 110 | 94 | 95 | 26 | 28 | 5.34 | 884 | 5.22 |
| Mike Scott | 1986 | MAN | sp | 31 | 5.03 | 11 | 10 | 0 | 32 | 27 | 4 | 0 | 166.1 | 174 | 109 | 93 | 66 | 144 | 31 | 19 | 5.07 | 733 | 4.98 |
| Mellie Wolfgang | 1915 | COB | rp | 25 | 5.04 | 1 | 1 | 0 | 34 | 0 | 0 | 0 | 89.1 | 111 | 65 | 50 | 43 | 30 | 15 | 16 | 6.51 | 409 | 5.93 |
| Roy Halladay | 2005 | FLP | sp | 28 | 5.05 | 2 | 3 | 1 | 22 | 8 | 1 | 0 | 73.0 | 94 | 51 | 41 | 16 | 38 | 12 | 4 | 5.81 | 332 | 6.11 |
| Cy Falkenberg | 1914 | CRB | sp | 33 | 5.07 | 0 | 1 | 0 | 22 | 4 | 0 | 0 | 55.0 | 66 | 40 | 31 | 20 | 39 | 9 | 6 | 5.48 | 252 | 5.77 |
| Lefty Grove* | 1930 | BAY | sp | 30 | 5.09 | 10 | 11 | 0 | 31 | 31 | 3 | 0 | 178.2 | 202 | 113 | 101 | 69 | 144 | 21 | 19 | 5.13 | 794 | 4.89 |
| Roy Oswalt | 2001 | MAN | sp | 23 | 5.10 | 6 | 7 | 0 | 23 | 20 | 2 | 0 | 114.2 | 132 | 70 | 65 | 30 | 79 | 18 | 13 | 5.00 | 489 | 4.93 |
| Joe Horlen | 1964 | JS | sp | 26 | 5.12 | 8 | 8 | 0 | 24 | 24 | 6 | 1 | 133.2 | 139 | 76 | 76 | 71 | 51 | 20 | 18 | 5.44 | 594 | 5.10 |
| John Habyan | 1991 | BAY | rp | 27 | 5.15 | 1 | 1 | 2 | 36 | 0 | 0 | 0 | 64.2 | 92 | 46 | 37 | 24 | 44 | 3 | 8 | 6.23 | 308 | 6.34 |
| Elias Sosa | 1977 | JS | rp | 27 | 5.16 | 1 | 0 | 0 | 13 | 0 | 0 | 0 | 29.2 | 28 | 18 | 17 | 5 | 21 | 6 | 1 | 3.61 | 122 | 4.34 |
| Noodles Hahn* | 1902 | TEX | sp | 23 | 5.19 | 2 | 1 | 1 | 25 | 1 | 1 | 0 | 52.0 | 65 | 32 | 30 | 16 | 34 | 8 | 3 | 5.66 | 232 | 5.67 |
| Satchel Paige | 1931 | MOT | sp | 24 | 5.21 | 7 | 15 | 0 | 33 | 33 | 5 | 0 | 197.0 | 239 | 129 | 114 | 79 | 155 | 19 | 13 | 5.33 | 901 | 5.50 |
| Mordecai Brown | 1906 | VAN | sp | 29 | 5.23 | 12 | 11 | 0 | 29 | 29 | 6 | 0 | 179.0 | 190 | 107 | 104 | 64 | 124 | 29 | 17 | 4.77 | 773 | 4.85 |
| Dave Davenport | 1915 | MOT | sp | 25 | 5.28 | 10 | 6 | 0 | 25 | 25 | 4 | 0 | 148.1 | 169 | 111 | 87 | 72 | 84 | 26 | 15 | 5.94 | 674 | 5.75 |
| Orel Hershiser | 1985 | VAN | sp | 26 | 5.29 | 0 | 2 | 0 | 7 | 0 | 0 | 0 | 17.0 | 25 | 13 | 10 | 3 | 8 | 2 | 2 | 7.05 | 78 | 6.85 |
| Dazzy Vance | 1925 | WAS | sp | 34 | 5.30 | 1 | 5 | 0 | 27 | 10 | 0 | 0 | 88.1 | 118 | 57 | 52 | 33 | 83 | 11 | 11 | 6.46 | 406 | 6.19 |
| Vean Gregg* | 1911 | MIC | sp | 26 | 5.30 | 2 | 6 | 0 | 17 | 12 | 2 | 1 | 90.0 | 88 | 58 | 53 | 38 | 52 | 16 | 6 | 4.72 | 399 | 4.75 |
| Andy Pettitte* | 2005 | JS | sp | 33 | 5.30 | 10 | 15 | 0 | 29 | 29 | 5 | 1 | 185.0 | 215 | 113 | 109 | 73 | 84 | 30 | 17 | 5.73 | 812 | 5.50 |
| Chris Hammond* | 2002 | TEX | rp | 36 | 5.32 | 6 | 3 | 0 | 32 | 0 | 0 | 0 | 44.0 | 40 | 26 | 26 | 29 | 19 | 4 | 4 | 4.71 | 198 | 4.34 |
| Red Ames | 1911 | MOT | sp | 28 | 5.33 | 11 | 16 | 0 | 35 | 35 | 2 | 0 | 204.1 | 267 | 135 | 121 | 71 | 120 | 24 | 13 | 5.82 | 933 | 5.81 |
| Juan Guzman | 1992 | MIC | sp | 25 | 5.35 | 8 | 12 | 0 | 26 | 26 | 0 | 0 | 138.0 | 138 | 90 | 82 | 83 | 85 | 22 | 14 | 5.51 | 623 | 4.93 |
| David Cone | 1988 | COB | sp | 25 | 5.40 | 1 | 3 | 0 | 14 | 5 | 0 | 0 | 41.2 | 56 | 27 | 25 | 15 | 24 | 5 | 6 | 6.36 | 196 | 6.77 |
| Curt Schilling | 2002 | HUD | sp | 35 | 5.42 | 4 | 5 | 0 | 27 | 8 | 0 | 0 | 74.2 | 96 | 53 | 45 | 20 | 64 | 15 | 10 | 6.01 | 334 | 5.89 |
| Kevin Brown | 1996 | LH | sp | 31 | 5.46 | 7 | 8 | 0 | 31 | 24 | 2 | 1 | 130.1 | 184 | 97 | 79 | 34 | 50 | 21 | 10 | 6.93 | 616 | 6.90 |
| Jeff Nelson | 1995 | MIC | rp | 28 | 5.50 | 3 | 3 | 1 | 36 | 0 | 0 | 0 | 54.0 | 74 | 37 | 33 | 20 | 47 | 7 | 7 | 6.66 | 251 | 6.49 |
| Ugueth Urbina | 1998 | NYM | rp | 24 | 5.53 | 1 | 1 | 0 | 43 | 0 | 0 | 0 | 71.2 | 82 | 51 | 44 | 51 | 79 | 6 | 10 | 6.13 | 339 | 5.64 |
| Chief Bender | 1910 | JS | sp | 26 | 5.53 | 9 | 13 | 0 | 33 | 33 | 3 | 0 | 184.0 | 230 | 120 | 113 | 64 | 119 | 27 | 15 | 5.82 | 833 | 5.77 |
| Bob Turley | 1953 | WAS | rp | 22 | 5.53 | 0 | 1 | 0 | 31 | 0 | 0 | 0 | 53.2 | 56 | 36 | 33 | 40 | 61 | 4 | 7 | 5.69 | 252 | 5.48 |
| Eddie Cicotte | 1917 | COB | sp | 33 | 5.57 | 9 | 10 | 0 | 32 | 32 | 9 | 2 | 194.0 | 227 | 128 | 120 | 66 | 96 | 32 | 15 | 5.43 | 866 | 5.58 |
| Max Lanier* | 1943 | MAN | sp | 27 | 5.58 | 2 | 2 | 1 | 10 | 6 | 1 | 0 | 30.2 | 38 | 19 | 19 | 20 | 23 | 6 | 2 | 7.51 | 144 | 6.94 |
| Dolf Luque | 1923 | WAS | sp | 32 | 5.58 | 8 | 16 | 0 | 32 | 32 | 4 | 0 | 188.2 | 215 | 135 | 117 | 92 | 113 | 26 | 25 | 5.72 | 847 | 5.30 |
| Carl Hubbell* | 1933 | MOT | sp | 30 | 5.62 | 0 | 0 | 0 | 19 | 2 | 0 | 0 | 49.2 | 68 | 32 | 31 | 18 | 28 | 7 | 10 | 6.89 | 227 | 6.25 |
| Ed Walsh | 1909 | JS | sp | 28 | 5.75 | 4 | 12 | 0 | 29 | 29 | 1 | 1 | 158.0 | 186 | 112 | 101 | 84 | 76 | 27 | 18 | 6.23 | 727 | 6.17 |
| Ed Siever* | 1902 | STL | sp | 25 | 5.81 | 11 | 9 | 0 | 29 | 29 | 3 | 0 | 172.0 | 213 | 121 | 111 | 61 | 52 | 29 | 14 | 5.78 | 774 | 5.89 |
| Robb Nen | 2000 | VAN | rp | 30 | 5.84 | 5 | 5 | 3 | 34 | 0 | 0 | 0 | 37.0 | 34 | 26 | 24 | 17 | 41 | 6 | 3 | 4.51 | 161 | 4.12 |
| Rob Dibble | 1990 | MOT | cl | 26 | 5.85 | 2 | 7 | 24 | 56 | 0 | 0 | 0 | 75.1 | 88 | 53 | 49 | 45 | 89 | 12 | 7 | 6.42 | 357 | 6.28 |
| Rube Waddell* | 1902 | VAN | sp | 25 | 5.86 | 11 | 8 | 0 | 32 | 32 | 2 | 0 | 176.2 | 181 | 126 | 115 | 97 | 160 | 43 | 11 | 6.12 | 802 | 6.01 |
| Sparky Lyle* | 1972 | BAL | rp | 27 | 5.87 | 8 | 0 | 3 | 74 | 0 | 0 | 0 | 95.0 | 126 | 76 | 62 | 35 | 45 | 18 | 17 | 6.56 | 435 | 6.02 |
| Sid Fernandez* | 1985 | JS | sp | 22 | 5.93 | 5 | 6 | 0 | 43 | 10 | 0 | 0 | 118.1 | 127 | 90 | 78 | 73 | 113 | 22 | 11 | 6.10 | 550 | 6.05 |
| Steve Carlton* | 1972 | NYM | sp | 27 | 5.94 | 6 | 15 | 0 | 31 | 31 | 6 | 1 | 169.2 | 210 | 121 | 112 | 61 | 128 | 31 | 14 | 6.02 | 765 | 6.08 |
| Juan Rincon | 2004 | STL | rp | 25 | 5.96 | 1 | 1 | 0 | 14 | 0 | 0 | 0 | 25.2 | 27 | 20 | 17 | 18 | 28 | 4 | 1 | 5.78 | 123 | 5.63 |
| Johnny Allen | 1936 | STL | sp | 30 | 5.98 | 8 | 14 | 0 | 31 | 31 | 2 | 1 | 168.2 | 192 | 124 | 112 | 96 | 116 | 21 | 12 | 5.86 | 784 | 5.90 |
| Sandy Koufax* | 1965 | NYM | sp | 29 | 6.02 | 7 | 18 | 0 | 31 | 31 | 3 | 1 | 184.0 | 213 | 130 | 123 | 68 | 172 | 39 | 12 | 5.73 | 821 | 5.95 |
| Howie Camnitz | 1909 | MIC | sp | 27 | 6.03 | 7 | 12 | 0 | 32 | 32 | 3 | 1 | 165.2 | 196 | 129 | 111 | 85 | 81 | 29 | 13 | 6.26 | 771 | 6.08 |
| Lefty Gomez* | 1937 | WAS | sp | 28 | 6.06 | 12 | 11 | 0 | 33 | 33 | 6 | 2 | 178.1 | 207 | 138 | 120 | 87 | 121 | 29 | 19 | 5.97 | 820 | 5.72 |
| Spud Chandler | 1943 | COB | sp | 35 | 6.09 | 7 | 17 | 0 | 32 | 32 | 4 | 1 | 186.1 | 238 | 137 | 126 | 52 | 104 | 33 | 19 | 5.83 | 839 | 5.82 |
| Bruce Ruffin* | 1996 | CRB | rp | 32 | 6.11 | 2 | 4 | 2 | 27 | 0 | 0 | 0 | 28.0 | 36 | 21 | 19 | 16 | 17 | 6 | 4 | 7.51 | 136 | 7.00 |
| Joey Eischen* | 2002 | FLP | rp | 32 | 6.14 | 0 | 0 | 1 | 9 | 0 | 0 | 0 | 7.1 | 11 | 5 | 5 | 6 | 5 | 0 | 1 | 8.03 | 38 | 7.26 |
| Catfish Hunter | 1972 | BAL | sp | 26 | 6.15 | 3 | 8 | 0 | 58 | 9 | 1 | 1 | 124.1 | 152 | 98 | 85 | 68 | 54 | 23 | 17 | 6.69 | 581 | 6.49 |
| Willie Hernandez* | 1984 | COB | cl | 29 | 6.18 | 4 | 12 | 21 | 61 | 0 | 0 | 0 | 78.2 | 100 | 60 | 54 | 36 | 59 | 12 | 10 | 6.45 | 363 | 6.01 |
| Hal Newhouser* | 1946 | MIC | sp | 25 | 6.21 | 11 | 11 | 0 | 34 | 34 | 2 | 0 | 187.0 | 235 | 147 | 129 | 87 | 190 | 29 | 11 | 6.29 | 880 | 6.33 |
| Bryan Harvey | 1993 | HUD | rp | 30 | 6.23 | 1 | 4 | 1 | 33 | 0 | 0 | 0 | 39.0 | 50 | 32 | 27 | 15 | 29 | 8 | 2 | 6.41 | 183 | 6.79 |
| Homer Hillebrand* | 1905 | WAS | rp | 25 | 6.26 | 2 | 3 | 0 | 34 | 1 | 1 | 0 | 77.2 | 88 | 60 | 54 | 49 | 50 | 20 | 11 | 7.23 | 360 | 6.76 |
| Tom Seaver | 1969 | BAL | sp | 24 | 6.35 | 7 | 18 | 0 | 28 | 28 | 3 | 0 | 147.1 | 171 | 117 | 104 | 76 | 73 | 40 | 20 | 7.10 | 683 | 6.40 |
| Deacon Phillippe | 1905 | CRB | sp | 33 | 6.37 | 8 | 16 | 0 | 35 | 35 | 0 | 0 | 176.2 | 235 | 157 | 125 | 65 | 110 | 32 | 10 | 6.52 | 847 | 6.64 |
| Damaso Marte* | 2003 | MAN | rp | 28 | 6.43 | 0 | 2 | 0 | 21 | 0 | 0 | 0 | 28.0 | 31 | 20 | 20 | 15 | 20 | 2 | 4 | 5.21 | 127 | 5.01 |
| Cannonball Redding | 1918 | BAL | sp | 27 | 6.46 | 1 | 1 | 0 | 3 | 3 | 1 | 0 | 15.1 | 18 | 11 | 11 | 6 | 19 | 4 | 1 | 6.53 | 66 | 6.25 |
| Ray Narleski | 1956 | CRB | rp | 27 | 6.61 | 0 | 0 | 0 | 17 | 0 | 0 | 0 | 31.1 | 35 | 31 | 23 | 16 | 17 | 6 | 7 | 5.91 | 142 | 5.22 |
| Earl Moore | 1903 | MIC | sp | 23 | 6.70 | 5 | 8 | 0 | 23 | 23 | 2 | 0 | 123.2 | 155 | 97 | 92 | 68 | 86 | 23 | 15 | 7.14 | 582 | 6.89 |
| Reb Russell* | 1916 | LH | sp | 27 | 6.75 | 1 | 2 | 0 | 21 | 4 | 0 | 0 | 53.1 | 76 | 47 | 40 | 19 | 16 | 10 | 6 | 7.04 | 252 | 6.99 |
| Brandon Webb | 2003 | STL | sp | 24 | 6.77 | 6 | 8 | 0 | 24 | 24 | 1 | 1 | 111.2 | 142 | 96 | 84 | 60 | 72 | 23 | 12 | 7.54 | 536 | 6.86 |
| Orval Overall | 1909 | MOT | sp | 28 | 6.79 | 7 | 14 | 0 | 32 | 32 | 2 | 1 | 155.0 | 201 | 133 | 117 | 81 | 112 | 27 | 14 | 7.10 | 729 | 6.99 |
| Jim Hearn | 1950 | MOT | rp | 29 | 6.82 | 0 | 3 | 0 | 16 | 0 | 0 | 0 | 33.0 | 42 | 29 | 25 | 14 | 23 | 7 | 0 | 6.88 | 159 | 7.20 |
| Claude Hendrix | 1914 | BAY | sp | 25 | 6.95 | 1 | 3 | 0 | 7 | 6 | 0 | 0 | 33.2 | 48 | 26 | 26 | 12 | 14 | 8 | 5 | 7.87 | 152 | 7.24 |
| Dick Radatz | 1964 | BAL | rp | 27 | 7.17 | 1 | 4 | 1 | 66 | 0 | 0 | 0 | 123.0 | 149 | 102 | 98 | 96 | 121 | 19 | 13 | 7.53 | 608 | 7.01 |
| Ewell Blackwell | 1947 | BAY | sp | 24 | 7.37 | 3 | 16 | 0 | 28 | 28 | 0 | 0 | 127.0 | 171 | 115 | 104 | 78 | 111 | 21 | 9 | 7.94 | 614 | 7.46 |
| Luis Tiant | 1968 | MOT | sp | 27 | 7.42 | 0 | 1 | 0 | 22 | 0 | 0 | 0 | 40.0 | 42 | 34 | 33 | 34 | 25 | 7 | 6 | 7.02 | 191 | 6.30 |
| Larry Corcoran | 1884 | NYM | sp | 24 | 7.57 | 3 | 20 | 0 | 32 | 32 | 2 | 0 | 164.0 | 225 | 148 | 138 | 96 | 74 | 30 | 22 | 8.12 | 782 | 7.08 |
| Jake Peavy | 2004 | MAN | sp | 23 | 7.92 | 0 | 1 | 0 | 12 | 2 | 0 | 0 | 30.2 | 48 | 28 | 27 | 15 | 17 | 6 | 5 | 9.13 | 152 | 9.46 |
| Elmer Steele | 1908 | STL | sp | 22 | 8.58 | 0 | 0 | 0 | 22 | 0 | 0 | 0 | 43.0 | 68 | 41 | 41 | 9 | 24 | 13 | 6 | 8.58 | 206 | 8.24 |
| Vida Blue* | 1975 | NYM | sp | 25 | 8.81 | 3 | 15 | 0 | 29 | 29 | 4 | 0 | 127.2 | 190 | 132 | 125 | 67 | 80 | 27 | 9 | 8.83 | 631 | 8.80 |
| Francisco Cordero | 2004 | BAY | rp | 29 | 9.82 | 2 | 2 | 0 | 15 | 0 | 0 | 0 | 18.1 | 37 | 22 | 20 | 23 | 12 | 0 | 4 | 14.49 | 109 | 10.90 |