Neurophysiologic mechanisms for encephalopathy

by Marian Rissenberg, Ph.D. & Susan Chambers, M.D.

the Lyme Times, Vol. 20, January-March 1998, pp. 30

1) Diffuse cerebral diffusion abnormalities

2) Alterations in cellular metabloism at the cortical level

3) Neuro transmitter abnormalities

4) Neurotoxic substances

As with a head injury, the patient may "look fine" though they are having difficulty with very basic work, social and day to day functioning.

See article "Distinct pattern of cognitive impairment noted in study of Lyme patients"