* Confederation Cup added rounds of 16/32 vs losers of champions league

2015 Confederation Cup (Semi Finalist)
Preliminary round
Zamalek-BYE
1st round (Round of 32)
Zamalek 3/1 Rayon Sports (Rwanda)-(Ahmed Eid Abdel Malek 6" Pen, 45" / Ahmed Tawfik 37")
Rayon Sports (Rwanda) 0/3 Zamalek-(Ahmed Eid Abdel Malek 33" / Ali Gaber 53' / Ibrahim Salah 56") 
2nd round (Round of 16)  
Zamalek 0/0 Fath Union Sport de Rabat "FUS Rabat" (Morocco)
Fath Union Sport de Rabat "FUS Rabat" (Morocco) 2/3 Zamalek-(Basem Morsi 15" / Omar Gaber 84" / Hazem Mohamed Emam II 90+5") 
Added Round of 16 vs Losers of Champions League 3rd round
SM Sanga Balende (RD Congo) 1/0 Zamalek
Zamalek 3/1 SM Sanga Balende (RD Congo) (Ayman Hefny 48" / Omar Gaber 64" / Khaled Qamar 78")

Quarter Final - Group B   

Zamalek 1/0 CS Sfaxien "Safaques" (Tunisia)-(Abdoulaye Cissé 90")

 
Orlando Pirates (South Africa) 1/2 Zamalek-(Maarouf Youssef 72" / Moustafa Fathi  83")

Zamalek 2/0 AC Leopards (Congo)-(Basem Morsi 2" / Ayman Hefny 36" Pen)

AC Leopards (Congo) 1/0 Zamalek

CS Sfaxien "Safaques" (Tunisia) 1/3 Zamalek-(Mahmoud Abdel Monem "Kahraba" 54" / Ahmed Hammoudi 80", 90+3" Pen)

Zamalek 4/1 Orlando Pirates (South Africa)-(Ahmed Tawfik 14" / Ahmed Hassan Mekki 37" / Moustafa Fathi 62" / Mahmoud Abdel Monem "Kahraba" 67")

Semi Final
Etoile du Sahel "Al-Najm Al-Sahily" (Tunisia) 5/1 Zamalek-(Ayman Hefny 25")
Zamalek 3/0 Etoile du Sahel "Al-Najm Al-Sahily" (Tunisia)-(Mahmoud Abdel Monem "Kahraba" 12", 55" Pen / Own Goal "Ghazi Abdel Razek" 70")   

2018 Confederation Cup
Preliminary round 
Zamalek-BYE  

1st round (round of 32)
Wolaitta Dicha SC (Ethiopia) 2/1 Zamalek (Emad Fathi 36")  

Zamalek 2/1 (3-4 P) Wolaitta Dicha SC (Ethiopia) (Ahmed Madbouli 45+2" Pen, 48")

2018/2019 Confederation Cup

Preliminary round
Zamalek-BYE  

1st round (Round of 32)

Zamalek 7/0 AS CotonTchad (Chad) (Mahmoud Abdel Monem "Kahraba" 11" / Ferjani Sassi 15" / Kabongo Kasongo 22", 41" / Moustafa Fathi 27", 56" / Omar El-Said 82") 
AS CotonTchad (Chad) 2/0 Zamalek 

2nd round (Added Round of 32) vs Losers of Champions League 1st round

Ittihad Tanger IRT (Morocco) 0/0 Zamalek 
Zamalek 3/1 Ittihad Tanger IRT (Morocco) (Ibrahim Hassan II 45" / Omar El-Said 55" / Youssef Ibrahim "Obama" 85") 

3rd round (Round of 16) - Group D

Gor Mahia (Kenya) 4/2 Zamalek (Ibrahim Hassan II 7", 44")
 
Zamalek 1/1 Nasr Hussein Dey (Algeria) (Khalid Boutaïb 14")

Zamalek 1/1 Petro Atlético "Atlético Petróleos de Luanda" (Angola) (Youssef Ibrahim "Obama" 90+4")

Petro Atlético "Atlético Petróleos de Luanda" (Angola) 0/1 Zamalek (Hamid Ahaddad 27")

Zamalek 4/0 Gor Mahia (Mahmoud Alaa 12" / Youssef Ibrahim "Obama" 25" / Ferjani Sassi 84" / Omar El-Said 87")
 

Nasr Hussein Dey (Algeria) 0/0 Zamalek

Quarter Final

Hassania US Aghadir (Morocco) 0/0 Zamalek 

Zamalek 1/0 Hassania US Aghadir Morocco) (Ibrahim Hassan II 49") 

Semi Final

Zamalek 1/0 Etoile Du Sahel "Al-Najm Al-Sahily" (Tunisia) (Mahmoud Abdel Monem "Kahraba" 36") 

Etoile Du Sahel "Al-Najm Al-Sahily" (Tunisia) 0/0 Zamalek 

Final  
Renaissance Sportive de Berkane "Nahdat Berkane" (Morocco) 1/0 Zamalek 

Zamalek 1/0 (5-3 P) Renaissance Sportive de Berkane "Nahdat Berkane" (Morocco) (Mahmoud Alaa 55" Pen)