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Complete Information on Headaches

         

Common causes of Headaches

Chronic fatigue Emotional Stress Hormonal fluctuations
Weather/Seasonal changes Travel through time zones Altitudes
Skipping/delaying meals Sensory stimuli Medications
Caffeine Certain foods Alcohol

Types of Headache
Urgent Headaches 
Urgent headaches may be immediately life-threatening, and should be treated promptly. 

Subarachnoid hemorrhage ("aneurysm") 
Patients typically describe a headache related to a leaking aneurysm as a sudden, "thunderclap" headache, often the "worst headache of my life" (an "aneurysm" is a swelling of a blood vessel in the brain). After this sudden onset, the pain may persist at a high or low intensity for days. Abnormal neurological symptoms may occur, including brief loss of consciousness at the onset of the headache, a stiff neck, or eye movement abnormalities. 

Such a headache mandates prompt evaluation by a physician, since a missed aneurysmal leak can result in a catastrophic stroke or death. Evaluation typically takes place in an emergency department, and includes a brain computed tomography (CT) scan. 
A spinal tap (looking for leaked red blood cells) may be necessary to completely rule out the diagnosis. An MRI may be useful, but typically requires neurology or neurosurgery consultation. 

The definitive treatment for subarachnoid bleeding is surgery, although calcium channel blocking drugs (tioclodipine) may limit damage. 

Temporal (giant cell) arteritis 
Patients with temporal arteritis (TA, an inflammatory process involving the walls of medium-sized arteries) are usually over age 50. Its symptoms are newly experienced localized headache, scalp tenderness and diminished pulse over the temple area , fevers, and aches. An unusual symptom highly suggestive of TA is "jaw claudication," or cramping of the jaws while chewing. 
Blindness (due to involvement of the ophthalmic artery) is a frequent complication, and may be prevented with prompt therapy. 
Blood tests reveal intense inflammation (with a high "ESR" test), and definitive diagnosis is made by finding inflammation on a biopsy specimen taken from the temporal artery. 
Treatment consists of prompt therapy with high-dose corticosteroids (such as prednisone), which should be instituted if the syndrome is suspected (even before definitive biopsy results return. 

Bacterial meningitis 
Acute bacterial meningitis is a virulent infection, and is typically manifest by an ill-appearance, fever, headache, stiff neck, and photophobia (avoidance of bright light). A rash may be present some forms. 
Diagnosis consists of a spinal tap showing white blood cells, chemical tests, and bacteriology studies. 
Treatment requires prompt antibiotic therapy. 

CT scans and MRIs 
While a "negative" CT of the brain is reassuring, the cost of imaging every person with headache is prohibitive (up to $3 billion/year in the US). Moreover, a CT scan will find a identifiable cause of headache (blood, tumor) in no more than 0.5 to 2.5% of patients, and most of these patients have abnormal clinical findings. 

Indications for immediate CT Scan or MRI for Headache

" Worst headache of my life "
Headache onset after exertion
Decreased alertness
Stiff neck
Abnormal neurological findings
Decline during observation
New headache lasting > 2 months in patient 40-60 years old

Special Headaches 
Brain tumor 
Though a fear for many headache sufferers, brain tumors are uncommon. Indeed, fewer than 20% of patients with brain tumors experience only headache as a symptom (the most frequent symptom is seizure and/or neurological abnormality on exam). 
Waking with a headache is said to be an important sign of a tumor-related headache, although this occurs frequently in chronic headaches 
Diagnosis is based on brain imaging and biopsy. 
Treatment is determined by an oncologist in consultation with a neurosurgeon. 

Cluster Headache 
Cluster headache commonly affects young- to middle-aged men. It is of short duration (30-90 minutes) and causes headache behind one eye, with eye redness, tearing, and nasal stuffiness on the involved side. Headaches are clustered over time (often separated by weeks to months); in times of headache activity, headaches may occur up to 6 times a day, often causing insomnia. 
Diagnosis is based on its classic presentation. 

Treatment includes high-dose anti-inflammatory medications (ibuprofen, others). For unknown reasons, over half get relief from breathing 100% oxygen by face mask. 

Coital Headache 
Coital headache occurs around the time of intercourse, and lasts from minutes to hours, and may be indistinguishable from subarachnoid hemorrhage. 
Diagnosis may require CT and spinal tap to rule out subarachnoid hemorrhage. 

Sinus Headache 
Typically occurring in conjunction with upper respiratory tract infection or allergic rhinitis/sinusitis, sinus headache is usually dull and constant, worse when bending forward, and may be associated with colored nasal discharge. 

Diagnosis may be made clinically, by x-rays, or on CT. 

Treatment is based on cause (antibiotics if bacterial, antihistamines/decongestants/intranasal steroids if allergic), and are 
supplemented by interventions to promote drainage (brief course of nasal spray, intranasal saline mist). 


Eye Strain Headache 
This headaches is associated with prolonged reading or staring at a computer screen (but not with astigmatism or refractive errors). 

Hormonal Headache 
While temporally related to menstrual cycle, menopausal flushing, or hormone use (oral contraceptives), this headache has no distinguishing features otherwise. 

Pain tends to diminish cyclically, or after menopause is completed (but only in 1/3 who develop menopausal headaches), or after hormone discontinuation. 

Benign Intracranial Hypertension 
Also known as "pseudotumor cerebri," this syndrome typically affects young, overweight women on certain medications (oral contraceptives, tetracycline, certain steroids, or vitamin A). The headache itself is nondescript, but exam findings include swelling of the optic nerve, which usually raises the specter of brain tumor. 
CT scan looks essentially normal, and a spinal tap reveals high pressure. 
Therapy includes corticosteroids. 

Post-Traumatic Headache (Concussion) 
"Concussion" is defined as loss of consciousness associated with head injury. Symptoms include headache, dizziness, and confusion; long-term symptoms are headache, irritability, fatigue, anxiety, insomnia, memory disturbance, and impaired concentration may persist for up to 18 months. 
A CT scan is typically normal. 
Treatment involves support with mild analgesia and reassurance. 

Migraine With Aura (Classic Migraine) 
A typical headache is heralded by an aura (blinking lights with partial vision loss, then sight restoration) followed in 25 to 60 minutes by a throbbing, unilateral headache associated with nausea, vomiting, and photophobia lasting 6-8 hours. 

Abortive treatment includes non-steroidal anti-inflammatory medications, anti-nausea medications, ergot derivatives, and other agents; preventive treatment involves various agents (see article on Migraine). 

Common Headaches 
While these headaches may have somewhat different causes, their manifestations (and treatment) are similar. Both may be triggered by stress. 

Migraine Without Aura (Common Migraine) 
Migraine headache tends to be throbbing and one-sided (typically over the temporal area), and precipitated by certain foods, strong smells, or the menstrual cycle (the ratio of female to male sufferers is 3 to 1). The time of day of onset varies. 
Diagnosis is based on symptoms and lack of neurological abnormalities. 
Treatment is the same as above. 

Tension Headache 
Often located in a both-sided "hatband" and neck distribution, tension headache is constant, precipitated by stress, has no associated symptoms, and usually occurs later in the day; female to male ratio is 1 to 1. 
Diagnosis is by clinical characteristics. 
Treatment involves a step-wise approach, beginning with over-the-counter non-steroidal medications or acetaminophen, followed by prescription-strength doses when necessary. Worse headaches may require migraine-type medications, such as Midrin (isometheptene, dichloralphenazone, and acetaminophen). Medications containing caffeine or butalbital are sometimes used (though risk of rebound headache increases). Prophylactic treatments similar to those used for migraine may be useful. 

Emed

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