| Rank | Song | Artist | Points | |
| 150 | |
Soul Survivor | Young Jeezy f/ Akon | 85 |
| 149 | |
Mighty O | Outkast | 186 |
| 148 | |
Girl Tonight | Twista f/ Trey Songz | 88 |
| 147 | |
Make It Rain | Fat Joe | 92 |
| 146 | |
I Should Have Cheated | Keyshia Cole | 92 |
| 145 | |
Baby Come Back | Vanessa Hudgens | 94 |
| 144 | |
Landing In London | 3 Doors Down f/ Bob Seger | 95 |
| 143 | |
Wind It Up | Gwen Stefani | 115 |
| 142 | |
I'm Feeling You | Santana f/ Michelle Branch | 123 |
| 141 | |
It Ends Tonight | The All-American Rejects | 132 |
| 140 | |
Hung Up | Madonna | 132 |
| 139 | |
Need A Boss | Shareefa f/ Ludacris | 135 |
| 138 | |
Ghetto Story (Part 2) | Cham f/ Alicia Keys | 141 |
| 137 | |
Beautiful | Damian Marley f/ Bobby Brown | 144 |
| 136 | |
Walk Away (Remember Me) | Paula DeAnda f/ The Dey | 147 |
| 135 | |
Georgia | Ludacris & Field Mob f/ Jamie Foxx | 148 |
| 134 | |
My Humps | Black Eyed Peas | 148 |
| 133 | |
I Don't Feel Like Dancing | Scissor Sisters | 154 |
| 132 | |
Hate Me | Blue October | 160 |
| 131 | Talk To Me | George | 162 | |
| 130 | |
Unbreakable | Alicia Keys | 169 |
| 129 | |
Take This Ring | Toni Braxton | 170 |
| 128 | |
Promise | Ciara | 179 |
| 127 | |
Lips Of An Angel | Hinder | 179 |
| 126 | |
I Write Sins, Not Tragedies | Panic! At The Disco | 181 |
| 125 | |
Don't Bother | Shakira | 183 |
| 124 | |
Irreplaceable | Beyonce | 187 |
| 123 | |
We Be Burnin' (Recognize It) | Sean Paul | 198 |
| 122 | |
You're Beautiful | James Blunt | 199 |
| 121 | |
Crash | Gwen Stefani | 200 |
| 120 | |
A Public Affair | Jessica Simpson | 201 |
| 119 | |
Wait A Minute | Pussycat Dolls f/ Timbaland | 210 |
| 118 | |
Show Me What You Got | Jay-Z | 211 |
| 117 | |
Here We Go | Trina f/ Kelly Rowland | 212 |
| 116 | |
That Girl | Frankie J. f/ Mannie Fresh & Chamillionaire | 214 |
| 115 | |
Right Where You Want Me | Jesse McCartney | 242 |
| 114 | |
Touch The Sky | Kanye West f/ Lupe Fiasco | 243 |
| 113 | |
Run It | Chris Brown f/ Juelz Santana | 246 |
| 112 | |
Shorty Like Mine | Bow Wow f/ Chris Brown & Johnta Austin | 250 |
| 111 | |
When I'm Gone | Eminem | 277 |
| 110 | |
Entourage | Omarion | 278 |
| 109 | |
Bad Day | Daniel Powter | 280 |
| 108 | |
Number One | Pharrell f/ Kanye West | 282 |
| 107 | Turn It Up | Johnta Austin | 290 | |
| 106 | |
I Think They Like Me | Dem Franchize Boyz f/ Da Brat, Jermaine Dupri, & Bow Wow | 288 |
| 105 | |
Stickwitu | Pussycat Dolls | 289 |
| 104 | |
Smack That | Akon f/ Eminem | 292 |
| 103 | |
Freeze | LL Cool J f/ Lyfe Jennings | 294 |
| 102 | |
Fergalicious | Fergie f/ Will.I.Am | 302 |
| 101 | |
Say Somethin' | Mariah Carey f/ Snoop Dogg | 303 |
Music Central's Top 150 Songs Of 2006 (100 - 51)
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