| Name | Date(s) | Notes |
| Cheryl Rabin | 02/10/03 | |
| Dave Rackowitz | 07/23/03 | |
| Danielle Radford | 09/19/06 | |
| Ross Radusky | 12/07-10/07 | |
| Daniel Raimo | 10/06/06 | |
| Roy Rankin | 11/02/04 | |
| Susan Rathke | 10/04/02 | |
| Lisa Razon | 11/02-03/05 | |
| Heather Redden | 02/25/05 | College Week III |
| Ajay Reddy | 12/03-04/03 | |
| Peggy Rees | 09/10/07 | |
| David Reichhold | 01/20-21/09 | |
| Tamika Reid | 09/20/06 | |
| Tamara Remy | 01/06/04 | |
| Diane Reul | 12/13-14/04 | Phoned Andy Jackson |
| Derrick Revolinski | 04/16/08 | |
| Margaret Rice | 03/15/05 | |
| Julie Richards | 06/27-28/06 | |
| Vena Riddick | 10/02/07 | |
| Jason Rindenau | 05/08/06 | College Week IV |
| Gary Roberts | 05/17/07 | Substitute host Tom Bergeron |
| Lisa Rock | 11/27-28/03 | |
| Roger Rock | 10/29-30/02 | Radio Week |
| Scott Rodas | 11/14/07 | TV Week |
| Kate Roffler | 01/08/04 | |
| Don Rommel | 03/31-04/01/08 | |
| Eric Root | 10/24-25/05 | |
| Linda Rose | 06/12/06 | |
| Steve Rosemarin | 05/09/07 | |
| Gary Rosen | 04/24-25/03 | |
| Lee Rosen | 09/29/05 | |
| Rich Rosenlof | 09/21/06 | Won $80,800 on "Jeopardy!" |
| Andy Ross | 06/10-11/09 | Substitute host Shaun Robinson |
| Delano Ross | 01/13-14/04 | |
| Samantha Ross | 03/14/05 | |
| Tracy Rosten | 12/04/03 | |
| Dave Roth | 01/25/07 | |
| Ron Rourk | 04/12/05 | |
| Jewryl Rowell | 02/04/03 | College Week I |
| Linda Roy | 01/11/05 | |
| Michelle Rudd | 04/27/05 | |
| Miguel Ruiz | 04/16/03 | |
| Walter Rupp | 02/18/04 | |
| Barry Russell | 01/16/03 | |
| Heather Russell | 04/20/04 | |
| Alex Rust | 06/15/06 | |
| Tim Saam | 04/21/08 | Substitute host Billy Bush |
| Karen Sagun | 01/09-10/03 | |
| Eve Salczynski | 04/11/05 | |
| Nick Santillo | 02/17-18/09 | Substitute host Cat Deeley |
| Jason Schaefer | 10/30/08 | |
| Meagan Scheuerman | 12/11/07 | |
| Michael Schreiber | 11/26-27/08 | |
| Jess Schulman | 04/23/07 | |
| Peter Scott | 04/04/03 | |
| Whitney Seibel | 09/16/03 | |
| Laura Seide | 05/17/07 | Substitute host Tom Bergeron |
| Dennis Sekaloff | 10/07/02 | |
| Matt Septynski | 12/15-18/06 | |
| Andrew Sessa | 02/25-26/04 | Remember the '90s Week |
| Sam Shainbrown | 07/16/03 | |
| James Shand | 11/04-14/05 | |
| John Sheeran | 12/15/03 | |
| Charles Shelton | 06/20-21/07 | |
| Warren Sheprow | 05/01-02/06 | |
| David Shimp | 03/10/03 | |
| Brian Shupe | 12/09/02 | |
| Carrie Shuping | 04/14/09 | |
| Katherine Shuster | 03/04/03 | |
| Kathy Siegel Rosenberg | 01/14/08 | |
| Michael Silver | 06/19/08 | |
| Elizabeth Simon-Axel | 09/27/04 | |
| Sean Sinclair | 12/05/02 | |
| Fred Singleton | 05/19/06 | |
| Mike Siscoe | 05/12/05 | |
| Matt Sittel | 09/09/09 | |
| Kanika Sloan | 05/26/04 | |
| Lee Smallwood | 10/05/05 | |
| Amy Smith | 03/06/03 | |
| Doug Smith | 05/25/07 | |
| Gemi Smith | 04/13/07 | |
| Lorrie Smith | 03/11/03 | |
| Nova Smith | 11/20/03 | Celebrity Scoop Week I |
| Rich Smock | 05/13/05 | |
| George Soltis | 06/10/09 | Substitute host Shaun Robinson |
| Danielle Sparks | 05/21-22/08 | |
| Lee Anne Spencer | 04/26/07 | |
| Michelle Staben | 01/29-30/03 | |
| Susan Stanley | 03/31-04/01/04 | |
| Todd Stapleton | 10/02/07 | |
| Suzanne Starnes | 12/09-10/02 | |
| Scott Steehn | 10/15/07 | |
| Abdul Steiner | 11/28-29/02 | |
| Mark Stepney | 03/31-04/01/03 | |
| Janelle Sterling | 09/11/07 | |
| Jason Stern | 10/07/02 | |
| Martha Stewart | 06/16-17/09 | |
| Dave Sticher | 10/19/04 | |
| Tom Stigi | 03/31/08 | |
| Phil Stoehr | 04/26/05 | Appeared in the film "To Wong Foo..." |
| Bethany Stollar | 11/02-03/06 | |
| Julie Stone | 01/08/08 | |
| Barbara Stonnell | 05/12-13/05 | |
| Diane Stratford | 02/11-12/03 | |
| Dave Strausman | 12/11-12/03 | |
| Mildred, Karen, & Nicole Stubbs | 11/17/08 | Three Generations Week |
| Cristina Stutler | 04/27/09 | |
| Tony Suffoletta | 04/30/04 | |
| Derek Tague | 11/12/02 | |
| Samantha Tate | 02/02-03/05 | |
| Holly Taylor | 10/17/02 | |
| Jill Taylor | 12/11/03 | |
| Chandra Teerie | 06/10/04 | |
| Alan Templeton | 06/27/07 | Substitute host Tim Vincent |
| Marianne Tertan | 10/08/07 | |
| Robert Tessaro | 12/16/04 | |
| Jeremy Thomas | 06/10-11/03 | |
| Joyce Thomas | 03/03/09 | |
| Mark Thomas | 12/13/07 | |
| Scott Thomas | 10/22-23/02 | |
| Trish Thompson | 04/18/07 | |
| Terry Timoll | 10/11-14/02 | |
| Carmelita Tiu | 11/25-26/02 | |
| Joey Tkach | 12/13/02 | |
| Corinne Torres | 11/04-05/08 | |
| Frank Tota | 06/10/05 | |
| Mary Clare Touma | 10/30/03 | |
| Rod Townsend | 01/30/04 | (see below) |
| Diana Traydon | 01/07/08 | |
| Luann Trigo | 06/23/08 | Substitute host Leeza Gibbons |
| Louie Tuzzino | 10/28/08 | |
| Angela Twining | 04/04/06 | |
| Rick Unterberger | 10/25/06 | |
| Dottie Urbach | 07/22/04 | |
| Andrea Urban | 01/21/09 | |
| Naya Urla | 03/04/04 | |
| Rose Vadella | 02/13-14/07 | |
| Penny Vahsen | 10/10/02 | |
| Anthony Valente | 06/25-26/08 | Substitute host Leeza Gibbons |
| Leonora Valeris | 05/16/08 | |
| Brian Van Sise | 02/11-12/04 | College Week II |
| Delana Venrick | 04/04-07/08 | |
| Anita Verdun | 06/27/05 | |
| Lael Verrips | 10/26/04 | |
| Dan Von Dohlen | 03/31/04 | |
| Jen Voss | 01/11/08 | |
| Michael Wallin | 03/07/03 | |
| Debbie Waltman | 12/04/03 | |
| Tyler Walz | 10/31/05 | |
| Eric Washington | 04/12/04 | |
| Ellene Weber | 09/11/08 | |
| Denise Weeks | 12/03-04/02 | |
| Lesleigh Weinstein | 10/15/03 | |
| Cindy Weldin | 05/31-06/01/05 | |
| Jordana Well | 09/24-25/07 | |
| John Whelan | 04/27/05 | |
| Jack Whitaker | 05/11/07 | |
| Greg White | 11/16/04 | |
| Patrick White | 04/18/08 | |
| Betsy Whitney | 01/31/07 | |
| Kenna Wiegand | 04/17/08 | |
| Nicole Wiegand | 10/12-13/04 | |
| Charlie Wilcox | 12/16/04 | Grandfather of Nicole Jurado |
| Rod Wilkins | 10/13/06 | |
| D. Andre Williams | 11/07/03 | Walk In & Win Week I |
| Michele Williams | 05/07/03 | |
| Revi Williams | 04/23/04 | |
| Tanya Willis | 05/07/07 | |
| Dalton Wilson | 04/12/07 | Grandson of country music legends Carl Smith and June Carter |
| Pat Wilson | 07/08/05 | |
| Ian Winkler | 05/15-16/06 | |
| Bob Wirges | 12/01-02/08 | |
| Chris Wirth | 01/08/08 | |
| Tammi Wolfarth | 06/27/07 | Substitute host Tim Vincent |
| Larry Wolff | 12/07-08/04 | |
| Russ Woodford | 12/06/04 | |
| Angela Works | 03/31/03 | |
| Randy Wormald | 12/07-08/05 | Teachers Week |
| Rachel Wurmlinger | 01/29/08 | |
| Janet Wygal | 10/07/02 | |
| Michael Yaki | 04/14-15/04 | |
| Vassiliki Yiannoulis | 02/09/04 | College Week II |
| Sandra Yoshizuka | 01/06-07/03 | |
| Daren Young | 12/04/02 | |
| Corinne Zarenberg | 02/18/05 | |
| Ursula Ziegler-Sullivan | 11/30/05 | |
| Diane Zielinski | 12/12-15/03 | |
| Mary Jane Zimmerman | 10/06/06 | |
| Tracy Zothner | 04/28-29/09 | |
| Anthony Zrake | 04/22-25/05 | Husband of Yvonne Zrake |
| Yvonne Zrake | 03/04/04 | Wife of Anthony Zrake |
Footnotes:
--Townsend's 01/30/04 appearance was cut short by incorrectly answering a flawed $32,000 question. The producers later reversed their decision and he returned to the Hot Seat. His monetary status remained unchanged as he failed to clear the $32,000 level the second time. His return segment never aired.
