| Anastasia Horne | Lark Madison (1997-1999) |
| Edward Albert | Dr. Bennett Devlin (1997-1998,1999) |
| Ivan Allen | Radio Show Host (1998) |
| George Alvarez | Detective Alex Garcia (1997-1999) |
| Judith Ames | Audrey Hardy, R.N. |
| Michael J. Anderson | Peter Zorin (1999) |
| Jennifer Aquino | Stacy (1998) |
| Tommy Aquino | Young Joe Scanlon (1999) |
| Tom Bosley | Bert (1999) |
| Alan Brooks | Agent Boynton (1998) |
| Joseph Cali | Bobby Mancusi (1998) |
| Sharon Cline | Bank Teller (1999) |
| Frank H. Conn | Frank Scanlon, Sr. (1998) |
| Shell Danielson | Dominique Stanton Taub Baldwin (1997) |
| Michael Dietz | Dr. Joseph Scanlon (1997-1999) |
| Anastasia Drake | Judy Parker (1999) |
| Jamie Farr | Ernie (1999) |
| Denise Galik-Furey | Rhonda Wexler |
| Mike Genovese | Gordie (1999) |
| Renee Griffin | Danielle Ashley (1997-1998) |
| Richard Gross | Janitor (1998) |
| Ron Hale | Mike Corbin |
| Christopher Halsted | John Kanelos (1998) |
| Lynn Hamilton | Alice Burgess |
| Jennifer Hammon | Dr. Karen Wexler (1997-1999) |
| Rib Hillis | Dr. Jake Marshak (1997-1998) |
| Dominic Hoffman | Byron Rollins (1997) |
| David Holcomb | Greg Cooper (1997,1998,1999) |
| Seth Isler | Simon (1998) |
| Rodney Van Johnson | Sebastian Dupre (1999) |
| Judith Jones | Janelle (1999) |
| Star Jones | Gatekeeper (1999) |
| Paul Kent | Dr. Noel Clinton (1999) |
| Michael Kostroff | Johnny LaLa (1999) |
| Vera Lockwood | Eleni Kanelos |
| Lisa Lord | Nurse Grace Sullivan (1997-1998) |
| Brian McLaughlin | Young Frank Scanlon (1999) |
| Howard S. Miller | Jimmy Knox (1998) |
| Debbi Morgan | Dr. Ellen Burgess (1997-1998) |
| Karmin Murcelo | Dr. Rodriguez (1999) |
| Wayne Northrop | Rex Stanton (1998) |
| Conor O'Farrell | Darren Leopold (1999) |
| Adam Paul | Bank Accounts Officer (1999) |
| Barry Pearl | Dr. Aikman (1998) |
| Eric Priestley | Young David 'DV' Bordisso (1999) |
| Marie-Alise Recasner | Dr. Ellen Burgess (1998-1999) |
| Michael Reisz | Lab Tech (1999) |
| Jim Richer | Aaron (1999) |
| Al Ruscio | Kosta Kanelos |
| Maggie Rush | Dr. Cassandra May (1998) |
| Al Sapienza | Mario (1998) |
| David Saunders | Winston Burgess (1997) |
| David Selberg | Dr. Perry |
| Richard Selzer | Himself (1999) |
| Barbara Stock | Nicole Devlin (1997) |
| Deborah Strang | Susanne Madison (1998) |
| Neil Tadkin | Don McTavish |
| Sandra Thigpen | Dr. Neumann (1997-1998) |
| Nick Vallelonga | Jimmy Black (1999) |
| Allan Wasserman | Gary Smith (1999) |
| Amy Wilson | Lark Madison (1999) |
| Marie Wilson | Dr. Karen Wexler Cates (1999-) |
| Hattie Winston | Alice Burgess (1998) |
| Lauren Woodland | Janelle (1999) |
