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Many factors contribute to schizophrenia but no one knows for sure. One cause that’s thought to contribute to schizophrenia is brain abnormalities. This is believed because of tests done of chronic schizophrenics, all of which had abnormal brain tissue (Myers 526). Genetics are also believed to play a role in schizophrenia. Children who have parents with schizophrenia have a 48 percent chance of getting it themselves (Myers 527).