Intro and Pharmacokinetics
Kinetics
Absorption and Excretion
Physiological Models
Clearance and Extraction Ratio

Drug Metabolism
Phase 1 Reactions
Cytochrome P450
Phase 2 Reactions
Pharmacogenetics

Enzyme Kinetics
Enzyme Systems
Enzyme Inhibitors

Receptor Theory
Receptor Antagonists

Signal Transduction
Second Messengers
Guanine Nucleotide Binding Proteins

cAMP/PKA System
cGMP/PKG System and Nitric Oxide

Lipases and IP3
Diacylglycerol and Protein Kinase C
PLA2 and Arachidonic Acid

Kinases and Phosphatases
Regulation and Substrate Recognition
Manipulating Phosphorylation Activities

Cell Excitability
Channel Modulation
Cellular Calcium Flux

Growth Factors

Transcription Factors
Steroid Hormones and HREs
Dual Function Domains