Pennsylvania State Route 380 runs across Northwestern Westmoreland County. This is a four-lane divided highway through most of the county. PA St Rt 380 does not pass thorugh any towns in Westmoreland County. PA St Rt 380 is not multi-plexed in Westmoreland County. PA St Rt 380 intersects the following highways in Westmoreland County. Pennsylvania State Route 286, near Murrysville.
