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Michael Poon's Shrine of Neurology

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Treatment Algorithm for Painful Diabetic Neuropathy


05 November 2004

Confirm diagnosis of diabetic neuropathy

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Improve glycemic control

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Oral regimen

Topical regimen

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Antidepressant: amitriptyline,
nortriptyline, imipramine,
doxepin

Capsaicin

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Anticonvulsant: gabapentin,
carbamazepine, phenytoin

Lidocaine cream

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Opiod analgesic therapy
plus tramadol

 

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Mexiletine

 

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Refer to pain clinic; consider spinal cord stimulation