Disease

Pathology

Alzheimer's Disease (AD)

20% loss of cortex

neocortical neurofibrillary tangles (NFT)

minority of Parkinson and DLB have AD changes

Diffuse Lewy Body Disease (DLB)

no loss of cortex

Lewy bodies in limbic and inferior temporal cortex

amyloid plaques

Parkinson's Disease Dementia

no loss of cortex

Lewy bodies may be present but not in cortex