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Categories of criteria
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Criteria
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Absolute |
1. Histologic demonstration
of the parasite from biopsy of a brain or spinal cord lesion |
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2. Cystic lesions showing the
scolex on CT or MRI |
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3. Direct visualization of
subretinal parasites by funduscopic examination |
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Major |
1. Lesions highly suggestive
of neurocysticercosis on neuroimaging studies* |
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2. Positive serum EITB#
for the detection of anticysticercal antibodies |
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3. Resolution of intracranial
cystic lesions after therapy with albendazole or praziquantel |
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4. Spontaneous resolution of
small single enhancing lesions& |
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Minor |
1. Lesions compatible with
neurocysticercosis on neuroimaging studies** |
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2. Clinical manifestations
suggestive of neurocysticercosis|| |
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3. Positive CSF ELISA for
detection of anticysticercal antibodies or cysticercal antigens |
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4. Cysticercosis outside the
CNS¶ |
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Epidemiologic |
1. Evidence of a household
contact with Taenia solium infection |
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2. Individuals coming from or
living in an area where cysticercosis is endemic |
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3. History of frequent travel
to disease- endemic areas
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* CT or MRI showing cystic
lesions without scolex, enhancing lesions, or typical parenchymal brain
calcifications. |
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# Enzyme-linked
immunoelectrotransfer blot assay using purified extracts of Taenia
solium antigens, as developed by the Centers for Disease Control and
Prevention (Atlanta, GA). |
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& Solitary
ring-enhancing lesions measuring less than 20 mm in diameter in patients
presenting with seizures, a normal neurologic examination, and no
evidence of an active systemic disease. |
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** CT or MRI showing
hydrocephalus or abnormal enhancement of the leptomeninges, and
myelograms showing multiple filling defects in the column of contrast
medium. |
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|| Seizures, focal neurologic
signs, intracranial hypertension, and dementia. |
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¶ Histologically confirmed
subcutaneous or muscular cysticercosis, plain X-ray films showing
"cigar-shaped" soft-tissue calcifications, or direct visualization of
cysticerci in the anterior chamber of the eye. |
|
ELISA = enzyme-linked
immunosorbent assay. |