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Genetics of hereditary spastic
paraplegia
Friday, November 05, 2004
Hereditary spastic paraplegia with identified gene loci or
mutations
| Notation |
Inheritance |
Gene location |
Gene identified |
| SPG1 |
XR |
Xq28 |
L1CAM |
| SPG2 |
XR |
Xq22 |
Proteolipid protein |
| SPG3 |
AD |
14q11.2-24.3 |
|
| SPG4 |
AD |
2p21-24 |
Spastin |
| SPG5 |
AR |
8q12-13 |
|
| SPG6 |
AD |
15q11.1 |
|
| SPG7 |
AR |
16q24.3 |
Paraplegin |
| SPG8 |
AD |
8q23-24 |
|
| SPG9 |
AD |
10q23.3-24.1 |
|
| SPG10 |
AD |
12q13 |
|
| SPG11 |
AR |
15q13-15 |
|
| SPG12 |
AD |
19q13 |
|
| SPG13 |
AD |
2q24-34 |
|
| SPG14 |
AR |
3q27-28 |
|
| AD = autosomal dominant; AR =
autosomal recessive; XR = X-linked recessive. |
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