CARDIOVASCULAR DISEASE / SYNDROME X
First, I would like to give you some background information that you can use to try and "peel away the layers" and discover why you may have cardiovascular problems. Granted, CVD can be hereditary, but, there may be an explanation for that, too. Research has found that insulin resistance, hypothyroidism and hypercholesterolemia can all be interrelated. People who are blood type O have been found to have a genetic tendency towards thyroid problems. They have also been found to have high IgA antibody levels which leads them to overly aggressive immune responses putting them at risk of autoimmune disease, especially of the THYROID, when not following a blood type specific diet. Specific immune conditions for blood type O have been found to be : candida albicans, thyroid disease, and inflammatory conditions ( arthritis, ulcers).
By eating a diet that is high in lectins (not following blood type specific recommendations), the "O" person is creating an unhealthy immune system and response. Since the thyroid has been found to be the weakest link, these lectins and the immune response may in all probability attack the thyroid(autoimmune thyroiditis). Both hyperthyroidism and hypothyroidism can be a result of either immune destruction or stimulation of thyroid tissue. It has been found through studies (PubMed and the National Library of Medicine), that there is a direct connection between hypothyroidism (low thyroid), hypercholesterolemia (elevated cholesterol) and hyperlipidemia (elevated cholesterol/triglycerides).
Extensive research shows that hypothyroidism leads to high levels of LDL and low levels of HDL, which in turn leads to increased oxidation of LDL, which results in atherosclerosis. If insulin resistance is also present, there can be a greater risk of cardiovascular disease. There are many clinical articles citing insulin resistance as either a factor or a result. There is a strong interaction between insulin resistance and high triglycerides. By eating the wrong foods (wheat, dairy, sugars), the "O" person may promote insulin resistance which elevates triglycerides, which lowers the fibrinolytic activity, which then causes atherosclerotic and coagulation risk factors , which, again, is a factor in coronary artery disease. It has been found through extensive research that there may be a relationship between hyperhomocysteinemia (elevated homocysteine levels) and hypothyroidism.
This information also pertains to blood types A and AB who eat incorrectly. The only difference is, people with those blood types are known to be genetically predisposed to heart disease and have a genetic risk of hypothyroidism, according to research on polymorphism and biochemical individuality.
Many research articles cite subclinical hypothyroidism relative to high LDL and more severe cases of hyperlipoprotienemia. The restoration of subclinical hypothyroidism to normal has resulted in large decreases in LDL. Post-menopausal women have, in most cases, been found to have sub-clinical hypothyroidism ( high TSH, greater than 10; normal free T4, below 10). Controlling hypothyroidism in women has often been found to result in lower lipid levels. In men, the results are not as good, pointing to insulin resistance as a primary factor. Studies have shown that T4 therapy alone does not lower HDL or triglycerides. Doses of T4 which suppress the TSH have been found to be most beneficial.
Subclinical hypothyroidism is known to manifest higher lipoprotein-A, triglycerides, total cholesterol, and LDL, and lower HDL test results. It has also been found to be a leading cause of diabetes.
Based on this information, the best overall dietary suggestions for people with hypercholesterolemia and hypothyroidism would be to follow their own blood type specific diets very closely. The results of an unhealthy diet, no exercise, and high stress can cause both a sluggish thyroid and insulin resistance. High carbohydrate diets (especially refined breads, pastas, sugars, fruit juices, etc.) lead to conditions of high triglycerides, insulin resistance, and hypothyroidism. Research is showing that people with high cholesterol may also have insulin resistance along with low fibrinolytic(breaking down of clots) activity . Abnormalities of carbohydrate metabolism are strongly related to hyperinsulinemia ,which leads to a cluster of cardiovascular risks known as insulin resistance syndrome or Syndrome X.
More often than not, high cholesterol is found along with an entire cluster of metabolic disorders. People with any of the 4 blood types can develop symptoms of this disorder called Syndrome X. This cluster may consist of: insulin resistance or hyperinsulinemia and glucose intolerance, high blood pressure, elevated triglycerides, high LDL cholesterol, low HDL cholesterol, and obesity. Research has shown that insulin resistance , at the core of these problems, interacts with the other disorders to promote the development of diabetes, atherosclerosis, and cardiovascular disease. Diet (the wrong diet) can create a vicious circle. By eating the wrong foods, (dairy,wheat,corn, and peanuts for blood type O; dairy, wheat, kidney beans, red meat for blood type A; and wheat, chicken, corn, peanuts for blood type B) the metabolism becomes altered. These incorrect foods, among others, contain substances known as lectins. The lectins go throughout the body and attach to insulin receptor sites. This attachment encourages the body to produce more and more insulin. As this goes on, the body becomes unresponsive to the insulin being produced. This is known as insulin resistance, and it,in most cases - signals obesity. The reason for this is that as lectins increase the production of insulin, that same insulin programs the fat cells of the body to store excess carbohydrates as body fat and to NOT burn fat for energy. Hence, insulin resistance always accompanies obesity. This only covers the obesity part of syndrome X. Insulin resistance generally leads to type II diabetes since the body is now resistant to the insulin and what insulin is excreted is no longer effective at keeping the blood glucose under control. As the body excretes more and more insulin to try and keep the blood glucose in balance, that excess insulin promotes excess cholesterol which may increase the risk of blood clots, and the high glucose increases triglycerides. The high glucose also contributes to the narrowing of blood vessels which leads to hypertension. It has also been found that the cells in the heart muscle (myocardium) can become resistant to insulin. The more insulin produced, the higher the risk of coronary heart disease.
In addition to watching the diet very carefully and eliminating the bad foods, it may prove to be very beneficial to use the kelp, bladderwrack (fucus vesiculosis). Bladderwrack, in a person with blood type O, may block the action of dietary lectins in the body, stopping the immune system from attacking itself. The fucus in bladderwrack is the same polysaccharide that is the blood type O antigen. Theoretically, since the sugar fucose is the blood type antigen on O blood cells, and in autoimmune conditions the immune system attacks itself, flooding the system with "fake" fucus would allow the lectins from the bad food or the immune system itself to attack them instead of the antigens in ,say, the thyroid or the joints or the stomach. This is likened to "anti-adhesion" therapy: "Don't attack the thyroid, attack the bladderwrack; don't attack the joints, attack the bladderwrack; don't attack the intestinal lining, attack the bladderwrack." When the immune system attaches to the fucus in the bladderwrack, instead of the body's own antigens, it is then flushed out of the system instead of creating inflammatory conditions which can then lead to other complications. Bladderwrack is better used in small amounts if hypothyroidism is a problem - at least until the cause of the thyroid problem is determined. Bladderwrack is a natural source of iodine, which helps in the production of T4. If your thyroid is making plenty of T4 but not converting it to the active thyroid hormone, T3, then it is not advisable to supplement and make more T4. Taken in small amounts, it could be very beneficial, however, due to the anti-adhesion properties. Bladderwrack or kombu (from good sources) are beneficial for most blood types if taken under supervision of a knowledgable health care practitioner.
Hypothyroidism, as has been found, is associated with high cholesterol. It is associated with a decrease in metabolism, which in turn, can cause obesity, the resulting insulin resistance, and high cholesterol.
This is the vicious circle. Interwoven within all of this is the consumption of refined carbohydrates, dairy, and a myriad of other bad foods per blood type to keep the circle going. In addition to all of this... When eating foods that are converted to sugar in your body, oxidative stress is placed on the body as it tries to burn the glucose for energy. This oxidative stress is in the form of mass amounts of free radicals and THIS contributes to faster aging, or degeneration of the body.
There is substantial evidence that elevated insulin increases the risk of colon, liver, pancreatic, breast and endometrial cancer. It has been found that insulin itself may play a role in cancer growth. It is considered a growth hormone. It is a well known fact that cancer is a sugar feeding organism, therefore, insulin resistance greatly increases cancer risk and promotion.
Some of the warning signs of Syndrome X/ cardiovascular disease are as follows:
Fasting glucose above 115 mg/dl
Total chol. above 240mg/dl
HDL- under 50mg/dl
Trig. Above 100mg/dl
Fibrinogen above 300mg/dl
C-reactive protein above 2mg/L
Hypertension: blood pressure above 140/90
HDL/LDL ratio: low ratio = increased risk for heart disease. High ratio = protective against heart disease.
Always keep this in mind:
THYROID HORMONE THERAPY, CHOLESTEROL LOWERING DRUGS, AND INSULIN INJECTIONS ARE MERELY TREATING SYMPTOMS, NOT GETTING RID OF THE CAUSES.
If/when taking statin drugs, it is often recommended to have creatine kinase levels measured. Creatine kinase levels are increased in myocardial infarction and progressive muscular dystrophy. The levels may also be elevated during statin drug therapy due to trauma to the skeletal muscles. Statin drugs cause the depletion of CO Q10 in the skeletal muscles (rhabdomyelosis), which causes destruction of muscles. This increases the creatine kinase. Keep in mind when discussing muscle destruction that the heart is a muscle.
Clinical studies have shown that cholesterol is actually not the primary culprit in cardiovascular disease. It is known that you can have a hemorrhagic stroke from a cholesterol that is too low. A low cholesterol may also put you at risk of a spontaneous subdural hematoma, under the right circumstances. Cholesterol is somewhat at the top of the pyramid. Cascading down from it is basically all of the steroidal hormones: pregnenalone, DHEA, estrogen, testosterone, - in fact, it is the cholesterol on your skin that converts to the active vitamin D3. Vitamin D is very important for your bones, for immunity, and is now known to be an anti-cancer agent. In addition to being the predicessor to the formation of hormones, cholesterol is responsible for the integrity of the vasculature. If it's lowered it too much, vascular integrity is lost - resulting in a hammorhagic stroke. Rather than cholesterol being the cause of cardiovascular disease, it is known now that high levels of the amino acid homocysteine and a protein called C-reactive protein may be the primary risk factors. Homocysteine circulates through the system and essentially shreds the vessels. Then, cholesterol comes along to patch up the damage. Cholesterol builds up only if the homocysteine levels are high and result in continuous damage to the vessels.
C-reactive protein is associated with inflammatory conditions and is a very good marker of a heart attack or stroke risk caused by destabilized athlerosclerotic plaque. When this plaque becomes destabilized, it can burst open and block the flow of blood through the arteries. It is best to keep both homocysteine and C-reactive protein as low as possible. Post-menopausal women taking Premarin or other synthetic hormone replacements, have been found to have drastically elevated C-reactive protein levels and a much higher risk of blood clots. Estrogens, per se, do not appear to increase the C-reactive protein, just synthetic estrogens, with or without progestins (synthetic progesterone). Elevated
C-reactive protein indicates a potentially destructive inflammatory autoimmune condition that predisposes one to a number of degenerative diseases (rheumatoid arthritis, pancreatitis, diabetes, cystic fibrosis, gastrointestinal cancer, and chronic renal failure)in addition to most chronic or autoimmune diseases. Fish oil( 1000-2000mg DHA), vitamin K, nettle leaf extract and DHEA have been found to suppress C-reactive protein. They have also been found to suppress the inflammatory cytokines (destructive cell damaging chemicals that increase with aging), tumor necrosis factor alpha (destructive to joint cartilage and the heart muscle- but, also used by the body to fight infections), interleukin-6(attacks bone and promotes the formation of fibrinogen that can induce a heart attack or stroke), interleukin 1B, and leukotriene B4. These cytokines are all involved in a chronic inflammatory syndrome. (These particular supplements should be discontinued during a time of active infection. If on blood thinning drugs, it is always best to check with your physician before using Vitamin K.)Homocysteine modulators - B6,B12, folic acid, and TMG(betaine)- have been found to lower levels of homocysteine. In a sense, it is the closest thing to malpractice for a physician to tell patients to "get your cholesterol down as low as possible". Your hormones become disrupted (you get all the problems associated with that), you have nothing to repair damage to the vasculature, and you lose the most natural source of the active Vitamin D3. Testing for C-reactive protein and homocysteine is important due to the ability to detect at-risk patients with normal cholesterol levels. Men with high levels were found to have twice the risk of future stroke, and four times the risk of future peripheral vascular disease. In women, C-reactive protein was the single strongest predictor of future vascular risk.
There has been some controversy surrounding the status of triglycerides as an independent risk factor for coronary heart disease. Some studies have found that treatment for isolated hypertriglyceridemia should not be recommended. They have shown that it is a poor marker of atherogenic risk and there have been no clinical trials that have directly addressed the question of whether lowering the triglyceride level reduces the number of clinical events. Hypertriglyceridemia seems to enhance the risk for the development of heart disease, but cannot be regarded as a counterpart of hypercholesterolemia as a risk factor. Studies have shown that people with established coronary heart disease and a high trigyceride level in association with a low HDL level or other features of syndrome X such as obesity, diabetes or hypertension may benefit from treatment. For people without established heart disease, hypertriglyceridemia should be considered a risk marker prompting aggressive treatment of other risk factors such as hypertension, diabetes, high LDL, and obesity. High triglycerides could be the first sign of insulin resistance. Too many carbohydrates (grains,starches,sugars) cause elevated triglycerides. Insulin resistance increases very bad cholesterol (VLDL). High triglycerides coincide with low HDL.
--- Adding coriander seeds to your diet has been found to enhance the breakdown of cholesterol by the liver.
--- Eat according to your blood type. Keeping the fiber high and fats balanced is always best. However, do NOT eat low or no-fat foods. They are known to increase the risk of insulin resistance - hence high cholesterol due to the very high refined carbohydrate content. Good, lean red meat, if you are blood type O, is known to be highly beneficial, as are vegetables and dark red fruits. Omega 3 fatty acids are very beneficial, however, it is not recommended to over-do it. High amounts of any fats can increase insulin production, which may increase cholesterol.
--- Moderate caloric restriction is recommended... it is better to leave the table not quite full rather than full. This has also been found to be a beneficial practice in the prevention and treatment of cancer.
--- Onions and garlic are an excellent source of natural sulfur and are known to be both antiviral and antiseptic. There has been extensive research concerning their cardiovascular benefits. NOTE: Garlic, especially, is known to have a blood thinning effect; don't use it therapeutically without a healthcare practitioner's guidance. The therapeutic method for utilizing garlic's benefits is crushed or chopped and raw. Mixing it with a small amount of raw honey may make it more palatable. Raw honey, in itself, is also very nutritious.
--- Be careful of carrots or any starchy vegetable. It is known that carrots raise blood sugar levels more than ice cream. They are considered a "starchy" vegetable, therefore they are carbohydrate dense - which will then cause an increase in insulin production, and the resulting high cholesterol. If carrots are eaten on occassion, it is best to eat them raw. It is best to avoid carbohydrate dense foods in general(whole grains, starchy vegetables, legumes, and fruits)in order to reverse Syndrome X. The amount of insulin your body produces depends on the carbohydrate density of the food you eat. Yams and sweet potatoes are known to bind completely with alkaline phosphatase, which is needed to break down cholesterol and triglycerides. This binding is not a beneficial effect and is best avoided. It is also why people of blood type O are able to eat a large amount of meat without the resulting increase in cholesterol..... they have high amounts of alkaline phosphatase in their system.
--- Avoid dairy (cheese, milk, ice cream, etc), wheat (bread, pasta, etc), corn, potatoes, kidney beans, navy beans, and peanuts. Studies show that those foods affect insulin receptors - sometimes permanently - and cause an increase in insulin which, again, may cause high cholesterol.
--- Consider eliminating or avoiding coffee. Continuing studies associate coffee with high cholesterol due to the fact that it destroys alkaline phosphatase which, as mentioned above, is the enzyme that breaks down the cholesterol in meat. Recent studies have shown coffee to be high in antioxidants, making it healthy for the heart. However, one must view the body as a whole system. Yes, it is high in antioxidants, however, it is also known to greatly stress the adrenal glands. When the adrenal glands are in a state of constant stress, you are in a state of constant "fight or flight" due to excess production of cortisol. Cortisol is known to increase inflammatory reactions in the body; most cardiovascular disease is currently found to be associated with inflammatory reactions. Hence, the finding that testing C-Reactive Protein is one of the most diagnostic tests to be used in the diagnosis of CVD. Keep in mind, also, that, unless coffee is organically grown, it is one of the most highly sprayed crops grown. Those pesticides are toxic to the body - especially the thyroid. The thyroid is extremely influential in the health of the heart and the control of cholesterol.
--- When cooking, use NO hydrogenated oils or margarines. They are known to elevate cholesterol because of anti-essential fatty acid action (trans-fatty acids). The best fats to use for sauteeing or cooking is ghee (clarified butter), organic, virgin coconut oil, and organic, virgin red palm oil. They will not go rancid when heated and are not trans-fatty acids. In fact, all three are very nutritious oils.
--- Avoid frying foods; it oxidizes fats. Cook at the lowest heat possible.
--- Sugar is known to increase LDL(low density lipoproteins) and triglycerides. It has been found to promote increased concentrations of plasma cholesterol, triglycerides, and uric acid.
--- Raw almonds (6-8 four times a week)are rich in arginine and found to cut cholesterol levels by 16 points over a period of 4 weeks.
--- Purple grape juice (unsweetened)may be beneficial in coronary heart disease. Studies show that it is a potent vasodilator yielding almost 3-fold improvement in blood flow. Always remember to buy unsweetened.
--- Exercise (walking 4-5 times a week for at least 30 minutes)is one of the best things you can do for your heart. Studies show that people with blood type O actually do better jogging 45-60 minutes at least 3 times a week.
--- Clinical studies have shown that oral contraceptives, diuretics, and blood pressure meds may elevate cholesterol.
--- Sunlight is known to have a beneficial effect on the metabolism of cholesterol. It is most effective to get at least 10-15 minutes a day three or four days a week of sunlight using no sunscreens or sunglasses. The best time is mid morning or mid afternoon. This is also known to be very beneficial for bone health.
--- In order to get or keep the thyroid in balance, it is best to stay away from green and black tea, fluoridated water, toothpaste with fluoride, and soy. Teas, not only because of the caffeine but, because green tea is VERY high in natural fluoride. Fluoride has been found to play a very large part in the reduction of thyroid hormone activity. In addition to that, it is an extremely toxic substance that should not be ingested in any way. It makes no difference whether it is natural or the toxic by-product of phosphate mining. Soy has properties (goitrogenic) that decrease thyroid hormone activity.
--- When you crave wheat or carbohydrates, consider having a small amount of protein (chicken, turkey, fish, walnuts, almonds(small amount), mozzarella or feta cheese (small amount), pumpkin or flax seeds, eggs, or non-fat yogurt).
---It has been found that fructose is as bad as sucrose in raising cholesterol and triglycerides. It may also increase excess chromium (which balances insulin and blood sugar) excretion.
--- Fenugreek seeds are known to be beneficial for both diabetes and heart disease. Studies have found that they may lower glucose levels and improve cholesterol profile.
--- Studies show that Eating 4 stalks of celery daily may keep blood pressure under control.(celery contains 3-n-butyl phthalide, which is a known blood pressure lowering compound)
Hypertension and insulin resistance tend to go hand in hand.
--- If hypothyroidism is suspected,(a morning basal temperature of 97.6 or below for 3 days in a row, goiter, difficulty in swallowing, intolerance to cold, fatigue, slow metabolism, weight gain, hair loss, migraines, depression) be very cautious of fluoride, chlorine and soy. In addition, eating vegetables in the brassica family (brussel sprouts, spinach, kale, cabbage, broccoli,etc) raw may also lower the thyroid. It is best to steam them lightly.
--- Attempt to avoid hypoglycemic conditions (watch processed carbohydrates or a high concentration of starchy vegetables and grains, sugars, caffeine, soft drinks. Stress is also a major factor). They may all ultimately be precursors to "Syndrome X" by causing insulin resistance. Hence, adult onset diabetes, high cholesterol, heart disease. Some symptoms of hypoglycemia are: fatigue, dizziness, heart palpitations, blurred vision, headache, irritability, depression, anxiety, night sweats, insomnia, and tightness in chest. People with hypoglycemia can become very aggressive and lose their tempers. Thyroid problems may also cause hypoglycemic problems.
--- Women who are peri-menopausal or menopausal are often estrogen dominant. Estrogen is known to block thyroid activity, thereby creating a hypothyroid condition. This, in turn, may lead to weight problems, blood sugar problems, cholesterol problems, heart problems - in essence, "Syndrome X".
--- Watch all carbohydrates (beans, grains, breads, some fruits, sugars). They often cause insulin resistance which can elevate triglycerides and cholesterol and lead to hypothyroidism, Syndrome X, and heart disease. When the content of dietary carbohydrate is elevated above the level typically consumed (>55% of calories), the blood concentration of trigycerides rise. This phenomenon is known as carbohydrate-induced hypertriglyceridemia. This is paradoxical because the increase in carbohydrates usually comes with a decrease in dietary fats, but, when you increase carbohydrates and decrease dietary fats, the content of blood fats (triglycerides) increases.
It is not necessary to take every supplement, recommended, every day. My suggestions are extensive so that you and your health care practitioner, can work together to put together different protocols to use at different times. It is never in your best interest to take every supplement every day. Except for the very important essential supplements such as calcium, magnesium, and digestive enzymes, most are best used cyclical. The cycle can be of varying lengths, but, they still need to be used in that manner. In that way, your body never becomes insensitive to the activity of the various supplements and they remain effective. Remember, the goal of nutritional and supplemental intervention is to eventually correct a problem, not treat the symptoms. You may not have to take these forever, as with drugs. Once a condition is stabilized or corrected, a good maintenance program could be set up. In some cases, there may be certain supplements you will want to use regularly. Having said all of that.....always keep in mind that it is never a wise choice to use supplements to "treat" elevated cholesterol or triglycerides UNLESS, at the same time you implement dietary and lifestyle changes. It is the same as "banging your head against a wall", and you will achieve negative results. Supplements are just that - "supplements". They support the body to heal itself, but, the real key to health is in nutrition and lifestyle choices.
- alpha lipoic acid 100mg /day - found beneficial in balancing insulin and glucose; decreasing the possibility that high cholesterol may be caused by existing insulin resistance. It is known to be beneficial with peripheral neuropathy, sciatica, and other neuropathies, and is known to be an effective liver detoxifier. Without it, cells are unable to use sugar to produce energy. Studies show lipoic acid to be a potent antioxidant, helping to recycle other antioxidants, and increase the production of glutathione in the body. Small doses are best - too much has been found to lower thyroid activity.
- Fish oil or Cod Liver oil -(1T. a day is the therapeutic dosage). This is very high in Omega 3s. A deficiency of omega 3 has been found to increase insulin resistance, leading to an elevated cholesterol. Fish oil also helps the body metabolize fats, and has been found to effectively increase HDL while decreasing LDL and lowering triglycerides and fibrinogen levels. It is instrumental in reversing Syndrome X. Clinical studies have found that fish oil is highly beneficial in the treatment of hypertriglyceridemia.
- Homocysteine modulators * (B6,B12,folic acid, TMG (betaine) Research has found that in most cases the homocysteine levels affect the cholesterol levels and keep them high. The B6 and B12 in this supplement may also be beneficial for neuropathy. (*trade name)
- Vanadyl sulfate - Studies have shown this to lower fasting glucose, LDL cholesterol, triglycerides, and blood pressure. It is known to be more beneficial to take vanadium in smaller amounts and in cycles, due to the fact that in large doses it may cause depression and kidney problems. Some researchers have found that vanadium mimics insulin, therefore, turning off the pancreatic cells that make insulin. After taking vanadium for a long time, then stopping, the body may temporarily underproduce insulin.
- Milkthistle - A known liver tonic and stimulator. High cholesterol often results when the liver doesn't metabolize cholesterol effectively.
- Bladderwrack - This is fucus vesiculosus. The fucus is the same as the blood type antigen for blood type O. Fucus protects the Blood Type O body from attacking itself (as in autoimmune disorders). The immune system attacks the fucus in the bladderwrack instead of the fucose on the body's blood cells. In some instances, autoimmune disorders aimed at the liver can prevent the liver from converting cholesterol to fecal bile acids which are then excreted.
- COQ10 - 30mg(triple absorpancy-Q-gel or Q-Absorb has excellent studies) This has been found to improve HDL cholesterol and lower triglycerides. It is also needed if using currently taking red yeast rice or statin drugs in order to prevent muscle disorders caused by the depletion of COQ10 (rhabdomyolysis). Studies have revealed that COQ10 lowers blood pressure in heart patients while improving measures of insulin/glucose regulation. Benefits are usually seen after 8 weeks. Research has shown this to be effective in carbohydrate metabolism. COQ10, in addition to the herbs hawthorne and motherwort, has been found to alleviate the symptoms of mitral valve prolapse (fatigue, chest pain, palpitations, breathlessness) - usually within a few months.
- Red Yeast Rice This has been found to lower LDL cholesterol 15-30% in 6-8 weeks in addition to raising HDL. Keep in mind, though, that this is somewhat a "natural" statin. It's effects on the muscles aren't as drastic as statins, but, taken over time, it can have the same effects. Please always remember........it is best to treat the cause of the elevated cholesterol, not the elevated cholesterol. Re-evaluate your nutrition and lifestyle. There are people who claim that high cholesterol is hereditary. That may very well be,however, my feeling is that the tendency may be hereditary. Simply because your mother and grandfather had high cholesterol does not mean that you will. It could very well be that a particular dietary regimen had been passed down through the generations. A dietary regimen that increased the tendency and risk of high cholesterol.
- Polycosanol Studies show this to significantly lower LDL, total cholesterol, and the LDL/HDL ratio. they have also shown polycosanol to increase HDL better than the statins and be more advantageous and better tolerated than the statins. No changes in hepatic enzymes were observed. Polycosanol has also been found to inhibit platelet aggregation and prevent lipid peroxidation. These, combined, reinforce its anti-atherosclerotic effect, significantly reducing systolic and diastolic blood pressure. Polycosanol is most beneficial when used after first being diagnosed with high cholesterol and other cardiovascular problems - before you have had a chance to initiate nutritional and lifestyle changes. Once those changes have been made and followed, it may very well be possible to slowly wean yourself from the polycosanol.
- Ester C/bioflavanoids has been found to decrease cholesterol, triglycerides, total lipids, and fibrinogen levels after 3 weeks of taking 1000mg. three times a day. The maximum effects were found after 6 months.
- Digestive enzymes are very important especially if the product has a good balanced complex containing lipase. People with Blood Type O should find a combination with no HCL. If Blood Type A, a product with HCL is best. Blood type B does well with bromelain. When using enzymes to lower cholesterol, it is important to take them on an empty stomach. Otherwise, they will simply aid in the digestion of food. Taking 2-3 two times a day, between meals may help lower cholesterol and break up fibrinogen. Using enzymes in this way is also known to be beneficial for pain. Enzymes help the system digest and metabolize all nutrients, including fats. They have been found to breakdown LDL and accelerate its removal. Bromelain in the enzyme complex has been found to lower fibrinogen levels.(you can also use bromelain separately to lower fibrinogen 500mg./ 3-4 times a day - 2000gdu)
- Soy or egg lecithin This is an immulsifier, liquidating fats, helping them to be removed from the body. Lecithin is high in phosphotidyl choline,and enhances fat metabolism. It has been found to lower total cholesterol and LDL, and raise HDL in 2-3 months.
- L-carnitine The therapeutic dosage of this supplement has been found to be 500mg.two times a day on an empty stomach. Studies have found that carnitine increases HDL, decrease cholesterol, and prevents diabetic ketoacidosis . It has also been found to help the body metabolize fat and use it for energy. High amounts have been found to reduce diabetic nerve damage. It is very beneficial for the cardiovascular system. Carnitine deficiency has been linked to numerous heart disorders: cardiac enlargement, congestive heart failure, cardio-myopathies...all respond to supplementation.
- Calcium, Magnesium - The therapeutic dosage has been found to be 2000mg calcium and 1000mg magnesium(elemental). The citrate or hydroxyapatite forms have been found to be the most absorbable and effective. In most cases, it may be best to take in divided doses. Research shows that they combine with fatty acids in the gut and may help decrease total cholesterol and triglycerides - showing a major decrease in the first week, and after 6 months, a decrease of 25%. Magnesium has also been found to protect against coronary artery spasms. People with diabetes often have low magesium. Calcium and magnesium always need to be taken in a 2:1 ratio (a 1:1 ratio with disorders such as fibromyalgia or CVD).
- Pantethine has been found to lower cholesterol from 18-24%. It may take 1-2 months, with the maximum benefits after 4 months. Studies show that it interferes with liver synthesis of cholesterol and it may also be very effective in lowering triglycerides. Pantethine shows NO toxicity.
- Alfalfa seeds - Used either as a powder or capsules. This is known to bind with cholesterol and bile salts preventing their absorption. Alfalfa, however, is known to cause inflammatory conditions and bind with thyroid hormone, so it is best not to use this. I mention it only because people have asked me about it or I have read about it.
- Chromium - (GTF or Trivalent is the best form to use). This is known to help balance or lower insulin, which has been found to increase LDL. Research has found that people with elevated insulin levels had decreased HDL and increased LDL, in addition to high blood pressure. Research has also found that diabetics also tend to have elevated cholesterol. Insulin resistance plays a large part in that.
- Tocotrienol complex Studies have shown that tocotrienols inhibit HMG-CoA reductase, which is the rate-limiting enzyme of the cholesterol biosynthetic pathway. It does this by increasing the concentration of cellular farnesol. Farnesol is known to suppress HMG-CoA reductase synthesis and enhance the destruction of this enzyme. Statin drugs are competitive inhibitors of the enzyme. Both total and LDL cholesterol have been reduced in animal studies by 44% and 60% respectively. The most effective source of tocotrienols is the palm oil derivative which has been found to be higher in the delta tocotrienols which have been found to be very beneficial in cardiovascular problems. Organic, virgin red palm oil is an excellant source for tocotrienols and is an excellent cooking oil.
- Vitamin E The most beneficial way to take vitamin E is as a balanced total E combination combining the 4 tocopherols and the 4 tocotrienols. Antioxidants are necessary to get rid of the free radicals found in any cardiovascular disorders. It has been found that high levels of insulin deplete vitamin E levels in the body. Taking an E complex has also been found to reduce glucose levels and restore more normal insulin function.
- gymnema sylvestre 75-150mg daily of this herb has been found to increase insulin secretion by the pancreas and possibly increase the efficiency of insulin. Resesarchers have found it to promote regeneration of pancreatic cells and improve neuropathic symptoms.
- Niacin - despite the fact that niacin has been found to be beneficial in lowering cholesterol, the dose needed often results in toxicity (liver damage, glucose intolerance). For the most part, it is NOT recommended to use niacin for this purpose.
- Pro-Fibe or any pectin supplement. This type of fiber has been found to bind to the substances necessary to carry cholesterol in the blood stream, making them unavailable as carriers. (exp.grapefruit pectin or apple pectin) Modified Citrus Pectin has been used in the treatment of prostate cancer, not high cholesterol. Good mucilaginous fibers (psyllium seed husks, oat bran, and otherwater soluble fibers) have also been found to lower LDL and raise HDL. Water in-soluble fibers such as wheat bran have not been found to affect serum cholesterol to any significant degree.
- Quercetin is known to inhibit aldose reductase which is involved in the synthesis of sorbitol from glucose. Sorbitol accumulates intracellularly and possibly leads to development of cataracts, retinopathy, and neuropathy.
- Inositol This has also been found to benefit neuropathy due to sorbitol accumulation.
- A good multiple vitamin/mineral combinationis the best base from which to create a beneficial nutritional program.
Please email me if you have any questions.
All of the previous information was obtained from numerous sources. Among them are:
Eat Right 4 Your Type - D'Adamo
Live Right 4 Your Type - D'Adamo
Nutritional Healing - Balch and Balch
Living Well With Hypothyroidism - Shoman
Disease Prevention and Treatment --Life Extension Foundation
Nutritional Influences on Illness - Werbach
Enzyme Therapy - Cichoke
PDR for Nutritional Supplements
PDR for Herbal Medicine
The Real Vitamin and Mineral Book - Lieberman
Protein Power - Eades
German Commission E Monograph
Natural Treatment for Diabetes
Alternative Medicine, The Definitive Guide
Encyclopedia of Natural Medicine - Pizzorno
Know Your Fats -Enig
Pocket Handbook on Diabetes
Natural Medicine for Heart Disease - Rothfeld
Syndrome X - Berkeson
No-Grain Diet - Mercola
The Thyroid Solution- Arem
Overcoming Thyroid Disorders -Brownstein
Principles and Practice of Phytotherapy - Mills/Bone
The New Holistic Herbal - Hoffman
Health Science Institute
Nutrition and Healing
Real Health Newsletter
Herb Research Foundation