on Arabic about جهاز المناعه لمكافحة المسارات المحددة للحساسيه ، والربو فهم strattera. Arabic

on Dutch about Immuunsysteem route vastgesteld voor de bestrijding van allergenen, astma Het begrijpen van Strattera. Dutch

on French about Système immunitaire parcours identifié de lutte contre les allergènes, l'asthme Comprendre Strattera. French

on German about Des Immunsystems identifiziert Pathway To Fight Allergene, Asthma Understanding Strattera. German

on Greek about Ανοσοποιητικό σύστημα κατάρτισης που προσδιορίζονται για την καταπολέμηση αλλεργιογόνα, το άσθμα Κατανόηση Strattera. Greek

on Italian about Sistema immunitario percorso individuato per la lotta contro gli allergeni, asma Strattera comprensione. Italian

on Japanese about アレルゲンと戦う免疫システムの経路発見、ぜんそく ストラテラを理解します。 Japanese

on Portuguese about Percurso identificados sistema imunológico para lutar contra a alérgenos, asma Compreender Strattera. Portuguese

on Spanish about Sistema inmunológico identificados vía para luchar contra los alergenos, el asma Entendimiento Strattera. Spanish

on English about Immune System Pathway Identified To Fight Allergens, Asthma Understanding Strattera. English



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Immune System Pathway Identified To Fight Allergens, Asthma

Immune System Pathway Identified To Fight Allergens, Asthma Understanding Strattera. Strattera with worldwide delivery Botulism Risk from Canned Green Beans. FDA is warning consumers about potentially contaminated canned cut green beans manufactured by New Era Canning Company, New Era, Mich. New Era is voluntarily recalling the green beans because they may be contaminated with Clostridium botulinum (C. botulinum), the bacterium that causes botulism. See payment and shipping options and choose online pharmacy suit you the best

Immune System Pathway Identified To Fight Allergens, Asthma

Immune System Pathway Identified To Fight Allergens, Asthma Understanding Strattera. Strattera with worldwide delivery Botulism Risk from Canned Green Beans. FDA is warning consumers about potentially contaminated canned cut green beans manufactured by New Era Canning Company, New Era, Mich. New Era is voluntarily recalling the green beans because they may be contaminated with Clostridium botulinum (C. botulinum), the bacterium that causes botulism. See payment and shipping options and choose online pharmacy suit you the best

For first time, researchers from University of Pittsburgh School of Medicine have identified genetic components of dendritic cells that are key to asthma and allergy-related immune response malfunction. Targeting these elements could result in more effective drugs to treat allergic disorders and asthma, according to a study reported in May edition of the journal Nature Medicine. Dendritic cells are vital to immune response in that they recognize, capture and introduce threatening organisms to T lymphocytes-other immune cells that secrete potent proteins called cytokines that surround and destroy invaders. However, the Pittsburgh team's study goes further to illuminate a pathway that allergens use to act directly on dendritic cells to propel differentiation into T lymphocytes that fight back.

" We now have identified a molecule, c-Kit, that's central to process of allergic response, " said Anuradha Ray, Ph. D. , co-corresponding author and professor of medicine and immunology in Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine. " We show that genes encoding for c-Kit and cytokine interleukin 6 ( IL-6 ) are significantly activated when allergens are present, but c-Kit is very first molecule that gets triggered. "

Interactions between viruses and bacteria and molecular steps that initiate the immune defense have remained largely unknown. Using cells cultured from c-Kit mutant mice, Doctor Ray, her husband and co-corresponding author Prabir Ray, Ph. D. , and their colleagues studied molecular reactions to assaults by cholera toxin and a standard allergen, house dust mites. In addition to c-Kit and IL-6, they found effects on stem cell factor and Jagged-2-immune system molecules that are parts of the activation process.

" We've known T-cell side of the story for many years, and we know that dendritic cells are important, but what we did not know was how the dendritic cell does what it does, " said Doctor Prabir Ray. " Therapy directed against c-Kit specifically on dendritic cells using compounds coupled to c-Kit inhibitors such as Gleevec, a drug that is already FDA-approved and used in cancer treatment, may alleviate allergic diseases and, potentially, inflammatory bowel disease. "

The Pittsburgh team incubated dendritic cells with cholera toxin and house dust mite allergens, finding that both substances induced significant secretion of c-Kit and IL-6, initial steps in a cascade resulting in activation of T helper cells.

" Dual upregulation of c-Kit and stem cell factor has been noted in some cancers, such as small cell lung cancer. IL-6 has been associated with cancers such as multiple myeloma, " said Doctor Anuradha Ray. " Collectively, similar approaches to inhibit c-Kit, in addition to Gleevec or other inhibiting compounds could alleviate multiple cancers. "

The University of Pittsburgh School of Medicine has filed a patent application regarding finding.

This study makes up doctoral dissertation of first author Nandini Krishnamoorthy, a student in Immunology Graduate Program, and was conducted in laboratory of Doctor Prabir Ray, associate professor of medicine and immunology, University of Pittsburgh School of Medicine.

In addition to Drs. Ray and Krishnamoorthy, authors are Timothy Oriss, Ph. D. , Melissa Paglia, B. S. , Mingjian Fei, M. S. , and Manohar Yarlagadda, M. S. , all of University of Pittsburgh School of Medicine; and Bart Vanhaesebroeck, Ph. D. , Queen Mary's School of Medicine and Dentistry, London.

The study was funded by the National Heart, Lung, and Blood Institute and the National Institute of Allergy and Infectious Diseases at National Institutes of Health.

University of Pittsburgh Medical Center


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Understanding Strattera.

uses of Strattera

Strattera is used to treat attention-deficit hyperactivity disorder ( ADHD ) . It works by helping to restore balance of certain natural chemicals in brain ( neurotransmitters ) . It may help to increase ability to pay attention, concentrate, stay focused, and stop fidgeting.

how to use of Strattera

Read Medication Guide provided by your pharmacist before we start using Strattera and each time you get a refill. If we have any questions regarding the information, consult your doctor or pharmacist.

Strattera may be taken with or without food. Take Strattera as prescribed, usually either as a single daily dose in the morning or divided into two doses in the morning and late afternoon/early evening; or as directed by your doctor.

Your dosage is based on your medical condition and response to therapy. Don't increase your dose or take it more frequently than prescribed.

Use Strattera regularly in order to get most benefit from it. Remember to use it at the same time ( s ) each day.

Inform your doctor if your symptoms persist or worsen.

side effects of Strattera

See also Warning section.

Stomach upset, nausea, vomiting, constipation, fatigue, loss of appetite, dry mouth, dizziness, trouble sleeping, menstrual cycle changes, or mood changes may occur while use Strattera. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed Strattera because he or she has judged that the benefit to we is greater than risk of side effects. Many people using Strattera don't have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

Strattera may rarely cause serious problems such as heart attacks or stroke. Seek immediate medical attention if we experience any of the following:

Strattera has very rarely caused very serious liver problems. If we notice any of following highly unlikely but very serious side effects, seek immediate medical attention: yellowing of skin or eyes, dark urine, severe stomach pain, " flu-like " symptoms ( e. g. , fever, chills, unexplained fatigue ) . If we experience any of these symptoms ask your doctor about whether or not we should ever take Strattera again.

Rarely, males may have a painful or prolonged erection lasting 4 or more hours. If this occurs, seek immediate medical attention, or permanent problems could occur.

A very serious allergic reaction to Strattera is rare. However, seek immediate medical attention if we notice any symptoms of a serious allergic reaction, including:

This is not a complete list of possible side effects. If we notice other effects not listed above, contact your doctor or pharmacist.

precautions of Strattera

Before taking Strattera, tell your doctor or pharmacist if you're allergic to it; or if we have any other allergies.

Strattera should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if we have:

Before using Strattera, tell your doctor or pharmacist your medical history, especially of:

Strattera may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages.

To minimize dizziness or fainting, get up slowly from a lying or seated position ( especially when we first start using Strattera or if your doctor changes your dose ) .

Caution is advised when using Strattera in the elderly because they may be more sensitive to its side effects, especially dizziness.

Caution is advised when using Strattera in children because it may have a minor effect on weight, growth rate, and final height. Monitor your child's weight and height and consult your doctor or pharmacist for more details.

Strattera should be used only when clearly needed during pregnancy. Discuss risks and benefits with your doctor.

It's not known whether Strattera passes into breast milk. Consult your doctor before breast-feeding.

interactions of Strattera

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring we for them. Do not start, stop, or change dosage of any medicine before checking with them first.

Certain medications taken with Strattera could result in serious, even fatal, drug interactions. Avoid taking MAO inhibitors ( e. g. , furazolidone, linezolid, moclobemide, phenelzine, procarbazine, selegiline, isocarboxazid, tranylcypromine ) within 2 weeks before or after treatment with Strattera. Consult your doctor or pharmacist for additional information.

Before using Strattera, tell your doctor or pharmacist of all prescription and nonprescription products we may use, especially of:

Check labels on all your medicines ( e. g. , cough-and-cold products, diet aids ) because they may contain ingredients that could increase your heart rate or blood pressure. Ask your pharmacist about safe use of those products.

This document does not contain all possible interactions. Therefore, before using Strattera, tell your doctor or pharmacist of all products you use. Keep a list of all your medications with you, and share list with your doctor and pharmacist.

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Botulism Risk from Canned Green Beans. FDA is warning consumers about potentially contaminated canned cut green beans manufactured by New Era Canning Company, New Era, Mich. New Era is voluntarily recalling the green beans because they may be contaminated with Clostridium botulinum (C. botulinum), the bacterium that causes botulism.

Use Eye Cosmetics Safely. April is Women's Eye Health and Safety Month. Here are tips from FDA about storing, applying, wearing, and removing eye cosmetics.

Food Label Helps Consumers Make Healthier Choices. The food label allows you to compare foods quickly and easily to choose the ones that best fit your dietary needs.

Pet Food Products Seized at PETCO Distribution Center. Consumers who bought animal food products from PETCO in 16 states should take certain precautions

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Immune System Pathway Identified To Fight Allergens, Asthma Understanding Strattera. Strattera with worldwide delivery Botulism Risk from Canned Green Beans. FDA is warning consumers about potentially contaminated canned cut green beans manufactured by New Era Canning Company, New Era, Mich. New Era is voluntarily recalling the green beans because they may be contaminated with Clostridium botulinum (C. botulinum), the bacterium that causes botulism. See payment and shipping options and choose online pharmacy suit you the best

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