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| Authentication : We declare that the web-report is our own work and does not contain plagiarised material. | |
| Level | Upper Secondary |
| Category | Category 1 - Experimental Research |
| Project Title | Cytotoxicity of Potential Metal-Based Anticancer Drug |
| Synopsis | Research
at the interface between inorganic chemistry, biology and medicine is
providing exciting new insights into biological processes and novel
ideas for the design of therapeutic agents. Since early history, metal
complexes have been used as pharmaceutical agents. Today, the most
important drug from the field of inorganic chemistry used for cancer
treatment is cisplatin. Unfortunately, it is limited to tumours that are
relatively rare. Majority of cancer mortalities today such as lung
tumours, liver cancers and adeno-tumours of the gastrointestinal tract
are either not affected by cisplatin or the extent of the effect is
negligible. Despite its limited applications, it has set the direction
for researchers to explore new metal complexes with potential cytotoxic
effects on cancer cells. In this project, it is proposed to explore novel copper (II) complexes for bioactivity in vitro. Thus, the research will be directed towards the cytotoxicity and mechanisms of action of these metal-based potential anticancer complexes. |
| Link to start page | Cytotoxicity of Potential Metal-Based Anticancer Drug |
| URL to external site (if any) | Cytotoxicity of Potential Metal-Based Anticancer Drug |
| Special requirements to view website (if any) | Software/Plug-ins : NIL Compatible Browser : Internet Explorer 6.0 & above Resolution : Best viewed in 1024x768 |
| Team Members (Name , Class & Index no) | Team Leader : YANG YIYU, 4A 36 Group Members : OOI CHEN FENG, 4A 24 WAN MELVIN, 4M 19 |
| Name of Teacher Mentor(s) | MR LOH SUAN JIN |
| Name of External Mentor (if any) | DR PETER LEE, NTU / NIE |
