Scientists at the South African Center for Scientific and Industrial Research were the first to successfully prove that Hoodia contains a miracle molecule that suppresses the appetite. Later, a human clinical trial was conducted by scientists in Leicester England. A group of morbidly obese men and women participated. Half the group were given Hoodia and half were given a placebo. At the end of 15 days, the group on Hoodia had reduced their food intake by 1000 calories a day. Given the average daily diet is around 2200 calories, this was a stunning success. It has been established that the P57 molecule found in wild harvested Hoodia Gordonii works by mimicking the effect that glucose has on nerve cells in the brain in effect fooling the body into thinking it is full, even when it is not, thus curbing the appetite. For most people, the real weight loss challenge has relatively to do with dieting, exercise, supplements, or how many calories you burn in the gym. The real challenge is controlling their hunger drive. People who are trying to lose weight seem to share the exact same problem. They have trouble getting their appetite under control. Hoodia gordonii, it seems, could make that much easier. Because overcoming your own hunger drive seems almost impossible unless you get some help. The hunger signal is only turned off when your hypothalamus thinks you've eaten enough food. Your hypothalamus -- part of your body's endocrine system -- decides this by sensing the rise of sugar (glucose) in your blood. Eat enough carbohydrates, and your blood sugar rises, which convinces your hypothalamus to tell your brain that you're no longer hungry. Hoodia, however, contains a chemical that gets picked up by your hypothalamus which thinks it's glucose. And as it turns out, this chemical is reportedly 10,000 times more potent than glucose in triggering the chemical receptors in your hypothalamus, and so it only takes a tiny bit of this chemical to trigger the cancellation of your hunger signals.
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