Classic Fried Catfish 3/4 cup 1 cup yellow cornmeal 1/4 cup all-purpose flour 2 teaspoons salt 1 teaspoon cayenne pepper 1/4 teaspoon garlic powder 4 U.S. Farm-Raised Catfish fillets Vegetable oil Combine cornmeal, flour, salt, cayenne pepper and garlic powder. Coat farm-raised catfish with mixture, shaking off excess. Fill deep pot or 12-inch skillet half full with vegetable oil. Heat to 350 degrees F. Add catfish in single layer, and fry until golden brown, about 5 - 6 minutes, depending on size. Remove and drain on paper towels.