| Abomination | Emil Blonsky | Villain | Tales To Astonish 90 | |
| Absorbing Man | Carl Creel | Villain | Journey into Mystery 114 | |
| Adversary | Adversary | Villain | Uncanny X-Men 187 | |
| Ahab | Rory Campbell | Villain | ||
| Alistair Smythe | Alistair Smythe | Villain | ||
| Annihilus | Annihilus | Villain | Fantastic Four Annual 6 | |
| Answer | Unrevealed | Villain | Spectactular Spider-man 92 | |
| Arcade | Unrevealed | Villain | Marvel Team-Up 65 | |
| Armada | Unrevealed | Villain | The Sensational Spider-man 0 | |
| Attuma | Attuma | Villain | Fantastic Four 33 | |
| Aura | Unrevealed | Villain | The Spectactular Scarlet-Spider 1 | |
| Bantam | Unrevealed | Villain | Uncanny X-Men 282 | |
| Baron Mordo | Karl Mordo | Villain | Strange Tales 111 | |
| Baron Zemo | Helmut Zemo | Villain | Captain America 276 | |
| Basilisk | Unrevealed | Villain | Morbius 5 | |
| Battlezone | Unrevealed | Villain | Spectactular Spider-man 210 | |
| Belasco | Belasco | Villain | Ka-Zar the Savage III 11 | |
| Bengal | Unrevealed | Villain | Daredevil 258 | |
| Black Tom | Tom Cassidy | Villain | Uncanny X-Men 101 | |
| Blackheart | Blackheart | Villain | Daredevil 270 | |
| Blacklash | Mark Scariotti | Villain | Tales of Suspense 97 | |
| Blackout | Unrevealed | Villain | Ghost Rider Vol. 2 #2 | |
| Black Knight II | Nathan Garrett | Villain | Tales To Astonish 52 | Deceased |
| Blastaar | Blastaar | Villain | Fantastic Four 62 | |
| Blizzard | Gregor Shapanka | Villain | Iron Man 86 | |
| Blood Wraith | Sean Dolan | Villain | Avengers Annual 22 | |
| Bloodaxe | Unrevealed | Villain | Thor 448 | |
| Bloodsport | Unrevealed | Villain | Wolverine 4 | |
| Boomerang | Fred Myers | Villain | Tales to Astonish 81 | |
| Boone | Unrevealed | Villain | Web of Spider-man 117 | |
| Brainchild | Unrevealed | Villain | Uncanny X-Men 62 | |
| Bullet | Unrevealed | Villain | Daredevil 250 | |
| Bullseye | Ben Pondexter | Villain | Daredevil 131 | |
| Bulwark | Unrevealed | Villain | Generation X 13 | |
| Calypso | Calypso Ezili | Villain | Amazing Spider-man 209 | |
| Cameron Hodge | Cameron Hodge | Villain | X-Factor 1 | |
| Candra | Candra | Villain | ||
| Cardiac | Eli Wirthem | Villain | Amazing Spider-man 344 | |
| Cardinal | Unrevealed | Villain | New Warriors 28 | |
| Carnage | Cletus Kasady | Villain | Amazing Spider-man 360 | |
| Carrion | Malcolm McBride | Villain | Spectactular Spider-man 25 | |
| Chakra | Unrevealed | Villain | Web of Spider-man 117 | |
| Chameleon | Dmitri Smerdyakov | Villain | Amazing Spider-man 1 | |
| Chance | Nicholas Powell | Villain | ||
| Changeling | Unrevealed | Villain | Uncanny X-Men 35 | Deceased |
| Charon | Charlie Ronalds | Villain | X-Factor Annual 8 | |
| Cobra | Klaus Voorhees | Villain | Journey into Mystery 98 | |
| Cobweb | Cobweb | Villain | Sleepwalker 3 | |
| Coldheart | Unrevealed | Villain | Spider-man 49 | |
| Commando | Mr. Bohannon | Villain | ||
| Constrictor | Frank Schlichting | Villain | Incredible Hulk 212 | |
| Crime Master | Nick "Lucky" Lewis | Villain | Amazing Spider-man 26 | Deceased |
| Crimson Dynamo V | Dimitri Bukharin | Villain | Iron Man 109 | |
| Cyber | Unrevealed | Villain | Marvel Comics Presents 85 | Deceased |
| Cyclone | Unrevealed | Villain | Amazing Spider-man 143 | |
| D'Spayre | D'Spayre | Villain | Marvel Team-Up 68 | |
| D.K. | David Kalen | Villain | The Spectactular Spider-man 230 | |
D.O.A. 
| Unrevealed | Villain | Generation X #1 | |
| Dark Phoenix | Jean Grey | Villain | Uncanny X-Men 133 | Deceased |
| Dark Raider | Reed Richards | Villain | Fantastic Four 388 | Deceased |
| Darkling | Henrique Manuel Gallante | Villain | New Warriors Annual 3 | |
| Deadaim | Unrevealed | Villain | Spectactular Spider-man 209 | |
| Deadzone | John Dezone | Villain | Moonknight Vol.3 #47 | |
| Deathbird | Unrevealed | Villain | Ms. Marvel 9 | |
| Deathwatch | Stephan Lords | Villain | Ghost Rider Vol.2 #1 | |
| Delilah | Unrevealed | Villain | Amazing Spider-man 414 | |
| Demogoblin | Demogoblin | Villain | Web Of Spider-man 86 | Deceased |
| Destroyer | None | Villain | Journey Into Mystery 118 | |
| Devos | Unrevealed | Villain | Fantastic Four 359 | |
| Diablo | Esteban Diablo | Villain | Fantastic Four 30 | |
Doctor Doom 
| Victor Von Doom | Villain | Fantastic Four 5 | |
| Doctor Octopus II | Carolyn Trainer | Villain | Amazing Spider-man 406 | |
| Dormammu | Dormammu | Villain | Strange Tales 126 | |
| Dracula | Vlad Dracula | Villain | Tomb Of Dracula 1 | Deceased |
| Dragon Man | None | Villain | Fantastic Four 35 | |
| DreadKnight | Bram Velsing | Villain | Iron Man 101 | |
| Eel | Leopold Stryke | Villain | Strange Tales 112 | |
| Emplate | Marius Saint Croix | Villain | Generation X 1 | |
| Enchantress | Amora | Villain | Journey into Mystery 103 | |
| Eric the Red | Davan Shakari | Villain | Uncanny X-Men 97 | |
| Erik the Red | Scott Summers | Villain | Uncanny X-Men 51 | |
| Excutioner | Skurge | Villain | Journey into Mystery 103 | Deceased |
Back to the opening page/ Alpha Flight through The Defenders/ Excalibur through the Hellions/ Heroes through the Inhumans/ The Invaders through The U.S. Govern./ Villains F-M/ Villains N-Z/ Villains in groups A-L/ Villains in groups M-Z/ W.H.O. through X.S.E./ And those on their own
