Heather North Kenney gets the title Queen of the Scooby Universe, if for no other reason, because she portrayed Daphne in more Scooby incarnations than anyone else. Her portrayal of Daphne occurred in four decades, starting in 1970 and ending in 2003.

Now, you might be saying to yourself, "Wait a minute. No Scooby cartoons were created during the 1990s." Well, Scooby and the Gang do appear in a cartoon that was produced during the 1990s. They appear in the Johnny Bravo series in the 07/21/97 episode titled Bravo Dooby-Doo.

Anyway, the Voice Over Herald summarizes Heather's time in the Scooby Universe:

"Her career, which spanned 40 years, was largely focused on voicing the character of Daphne. She took over the role from Stefanianna Christopherson in the second season of Scooby Doo Where Are You! When the producers started looking for a replacement, North’s friend and roommate Nicole Jaffe, who was already voicing Velma Dinkley, convinced her to audition. Jaffe felt that North was perfect to voice the role, and as it turned out, she was indeed!

North first voiced Daphne in Scooby Doo Where Are You! for 8 episodes in 1970. Then New Scooby-Doo Movies from 1972-1973. North continued voicing the teen detective ‘Danger Prone Daphne,’ and many other versions of the cartoon franchise from 1976 until 2003 including TV series and direct-to-video movies. She voiced Daphne for the last time in 2003 for Scooby-Doo! and the Monster of Mexico and Scooby-Doo! and the Legend of the Vampire.¹

Information Source

¹Heather North, Voice of Daphne Blake on Scooby-Doo, Dies at 71. Voice over Herald. Retrieved from http://www.voiceoverherald.com/heather-north-voice-daphne-blake-scooby-doo-dies-71/