The abnormalities associated with Proteus syndrome are usually present at birth. However, these signs may become more apparent with age. The severity of this disease varies widely throughout the persons affected by it. Complications caused by Proteus depend largely on the area affected by the syndrome and the severity of the problem.
Some of the signs and symptoms associated with Proteus include:
Overgrowth and partial enlargement of soft tissue and bone which usually affects the hands and/or feet, the skull (macrocephaly), and sometimes the whole of one side of the body (hemihypertrophy)