|
Home |
Printer Friendly (PDF version)
ISTERH 2004 PROGRAM SCHEDULE
NOTE: This is Part 1 (Sunday-Wednesday; November 7-10, 2004) of the Conference Program. Please click HERE to see Part 2 (Thursday-Friday; November 11-12) of the Conference.
NOTE: The times listed below represent the FINAL SCHEDULE for individual events and sessions throughout the conference.ISTERH acknowledges the generous financial support from the following organizations:
·America's Beef Producers ·Attenuon, L.L.C.
·Labcatal
·National Cancer Institute (National Institutes of Health, Department of Health and Human Services; grant award #R13 CA11335-01)
·Nobelpharma Co., Ltd.
·Pipex, Inc.
Summary and quick links to the program Part A:
Plenary Session #1: Improvement of Trace Element Nutrition in East and Southeast Asia: the Challenges
Plenary Session #2: Improving absorption and bioavailability to address iron deficiency
Plenary Session #3: Neurological Diseases & Trace Elements
Symposium A: Infectious Diseases & Trace Elements
Symposium B: The Link Between Zinc and Redox Metabolism and its Significance for Chronic Disease
Symposium C: Managing Trace Element Bioavailability
Symposium D: Presidents’ Session
Poster Session #1: Trace Elements and Cancer; Disorders of Aging; Fetal Development and Pediatric Disorders; Infectious and Immune Disorders; Molecular Nutrition for the Clinician
Poster Session #2: Bioavailability of Trace Elements and Dietary Patterns; Trace Elements and Cardiovascular and Pulmonary Diseases; Neurological Diseases and Neuropsychological Impairment
Special Presentations
Minisymposium #1: Trace Elements and Diabetes, Cardiovascular Diseases, and Fetal Development
Minisymposium #2: Trace Elements and Neurological Diseases and Neuropshychological Impairment; Toxicity of Trace Elements
Summary and quick links to the program Part B:
Plenary #4: Cardiovascular Diseases and Trace Elements
Plenary #5: International Trace Element Nutritional Issues: "Simultaneous deficiencies of iron and zinc - problems and some possible solutions"
Symposium E: Metabolic Syndrome & Trace Elements
Symposium F: Toxic Metals Causing Human Diseases in Asia
Poster Session #3: Trace Elements and Diabetes Mellitus, Metabolic Syndrome, and Obesity; Osteoporosis and Other Bone Disorders; Toxicity of Trace Elements
Minisymposium #3: Bioavailability of Trace Elements and Dietary Patterns
SUNDAY AFTERNOON, November 7, 2004
16:00 Main Entrance of Grand Ballroom
Registration desk opens
18:00 Poolside
Welcome and Greeting from Dr. Harold Sandstead, President ISTERH
18:05 Poolside
Welcome and Greeting from Dr. Songsak Srianujata, Chairman of ISTERH 2004 Host Committee
19:00 Poolside
Welcoming reception
___________________________________________________
MONDAY MORNING, November 87:30 Main Entrance of Grand Ballroom
Registration desk opens
7:30 Ante Room (next to Ballroom III)
Speaker Ready Room
8:00 Ballroom III
Monday posters open. Presentation time: 13:30-14:30
8:00 Foyer (in front of the Grand Ballroom)
Commercial Exhibits
8:30 Ballroom I and II
Assembly of all delegates 30 minutes before arrival of HRH
9:00 Ballroom I and II
Welcome and Opening of Meeting, Harold H. Sandstead, President ISTERH
9:05
Welcome and Greeting from Songsak Srianujata, Host of ISTERH 2004
9:10 Ballroom I and II
Opening Ceremony
9:40-10:40 Ballroom I and II
Plenary Session #1: Improvement of Trace Element Nutrition in East and Southeast Asia: the Challenges
Chair: Songsak Srianujata
Co-Chair: Emorn Wasantvisut
Purpose of Session: Trace element nutrition is an important public health problem for many populations of Asia. Deficiencies of iron, zinc, iodine, and selenium continue to cause wide spread morbidity. Iron deficiency continues to be the most common deficiency disease in Asia. Its intractable nature is has stimulated investigation of new methods of prevention including modification of plant-based foods to increase iron bioavailability. The prevalence of zinc deficiency in Asia, and its association with iron deficiency are areas of investigation. Zinc deficiency contributes to morbidity from respiratory infections and diarrhea in infants. As a consequence the WHO suggests inclusion of zinc with oral rehydration fluids. Efforts of respective governments, the WHO and NGOs have decreased the prevalence of iodine deficiency diseases. However the condition continues to cause significant morbidity in areas where effective iodine distribution has not been effective. Although selenium supplementation has decreased the prevalence of Keshan’s cardiomyopathy in China, low soil selenium continues to cause selenium deficiency in farm animals whose products become part of the food supply of the local human population. The possibility that selenium deficiency contributes to transformation of influenza viruses is a topic of continued investigation. The symposium brings together experts with firsthand knowledge of the trace element nutrition challenges facing public health officials in East and Southeast Asia. The symposium will provide information useful in establishing or updating public health policies related to trace element nutrition.
9:40 "Overview of Trace Element Nutrition in East and Southeast Asia," Songsak Srianujata
10:10 "Multiple Micronutrient Supplementation to Address Concurrent Micronutrient Deficiencies in Infants and Pregnant Women," Siti Muslimatun
10:40 Delegate Tea Break (Foyer [in front of Grand Ballroom])
11:10-12:30 Ballroom I and II
11:10 "Improvement of Trace Element Nutrition in China," Yiming Xia
11:40 "Zinc Nutrition and Respiratory Infection in Thailand," Sakda Pruenglampoo
12:10 "Control of Micronutrient Malnutrition in Vietnam: Current Situation and Strategies in Coming Years," NC Khan
12:30 Salathip/Angelini/La Tache
Delegate Lunch (covered in registration fee)
MONDAY AFTERNOON
13:30-14:30 Ballroom III
Poster Session 1
Category 2: Trace Elements and Cancer
P-1 2.01 TRACE ELEMENTAL PROFILE: AN INDEX FOR DISEASE PROGRESSION. Anindita Chakraborty* [1], Sudarshan Mathummal [1], Bidhan Mohanta [2], Mandira Barua [2], Amal Bhattacharya [3], Ajit Sinha [1]. Inter University Consortium for DAE Facilities, Calcutta Centre, Kolkata 700098, INDIA [1]; Gauhati University, Guwahati 781014, INDIA [2], Calcutta University, Kolkata 700019, INDIA [3]
P-2 2.02 ORAL CANCER-ITS RELATIONSHIP WITH SELENIUM AND ZINC: AN EPIDEMIOLOGICAL STUDY. Nabakanta Jana. Dept. of Zoology, Charuchandra College, 22 Lake Road, Calcutta-700 029, INDIA
P-3 2.03 LOW FREQUENCY OF MALIGNANT TUMORS AMONG WORKERS FROM BORON PROCESSING FACILITY 2: MALIGNANCY AMONG MINERS, EMPLOYERS, AND SUBJECTS WITH BORON-UNRELATED OCCUPATION. Bekir Sýtký Sayli [1], Uður Sayli* [2]. Boron Research Center, Balýkesir University, Balikesir, TURKEY [1]; Dept. Orthopaedics and Traumatology, Fatih University Hospital, Ankara, TURKEY [2]
P-4 LB.1 INHIBITORY EFFECT OF CHROSOPHORA TINCTURIA EXTRACT ON IRON-DEXTRAN MEDIATED MICE SKIN CARCINOGENESIS. Hassan Rezazadeh [1], Hossein Nazemiyeh [1], Ali Rajabi [1], Mehdi Zerahat [1], Bayram Abbaszadeh [1], and Mohemed Abdulla* [2]. Dept. Toxicology, School of Pharmacy, Tabriz University of Medical Sciences [1]; Trace Element Institute for UNESCO, International Center, 1 Place de, I'E Code [2], Lyon Cedex, 07, FRANCE
Category 5: Trace Elements and Disorders of Aging
P-5 5.02 TRACE ELEMENTS IN CEREBROSPINAL FLUID IN SUBJECTS WITH ALZHEIMER’ DISEASE AND NORMAL COGNITION. Nina Johansson* [1], Maria Eriksdotter-Jönhagen [2], Hans Basun [3], Ilja Rudshkin [4], Monica Nordberg [1]. Inst. Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, SWEDEN [1]; Dept Neurotec, Section of Clinical Geriatrics, Karolinska Institute and Karolinska University Hospital, Huddinge, SWEDEN [2] , AstraZeneca, Clinical Science, R&D Södertälje, SE-151 85 Södertälje and Dept. of Public Health/Geriatrics, Uppsala University Hospital, SE-751 25 Uppsala, SWEDEN [3]; Analytica AB,Aurorum 10, S-977 75 Luleå, SWEDEN [4]
P-6 5.03 DISTURBANCES OF CERTAIN TRACE ELEMENT LEVELS IN PATIENTS WITH BATTEN’S AND PARKINSON DISEASES . Tuomas Westermarck*, Erland Johansson, Faik Atroshi. Rinnekoti Cesearch Center, Espoo, FI-02980; Applied Biochemistry Unit, Huddinge Hospital, S-14186; Dep. Vet. Clinical Sciences, Pharmacology, University of Helsinki, FINLAND
Category 6: Trace Elements and Fetal Development and Pediatric Disorders
P-7 6.01 IODINE STATUS OF PREGNANT WOMEN PARTICIPATING IN THE SEYCHELLES CHILD DEVELOPMENT NUTRITION STUDY . Maxine P. Bonham* [1], Emeir M Duffy [1], J. J. Strain [1], Julie Wallace [1], Paula J. Robson [1], Conrad Shamlaye [2], Gary J. Myers [3]. Northern Ireland Centre for Food and Health (NICHE), University of Ulster, Coleraine BT52 1SA, NORTHERN IRELAND [1]; Ministry of Health, SEYCHELLES [2]; Environmental Medicine, University of Rochester School of Medicine and Dentistry, USA [3]
P-8 6.04 IRON STATUS OF PREGNANT WOMEN AND INFANTS PARTICIPATING IN THE SEYCHELLES CHILD DEVELOPMENT NUTRITION STUDY. Emeir M. Duffy* [1], Maxine P. Bonham [1], J. J. Strain [1], Julie Wallace [1], Paula J. Robson [1], Conrad Shamlaye [2] and Gary J. Myers [3]. Northern Ireland Centre for Food and Health (NICHE), University of Ulster, Coleraine BT52 1SA, NORTHERN IRELAND [1]; Ministry of Health, SEYCHELLES [2]; Environmental Medicine, University of Rochester School of Medicine and Dentistry, USA [3]
P-9 6.06 EPIDEMIOLOGICAL STUDY OF CHILDREN'S HAIR ELEMENT PATTERNS FROM VARIOUS RUSSIAN CITIES. Yulia Lobanova [1], Vasily Demidov [1], Svetlana Notova* [2]. Center for Biotic Medicine, 125047, PB.56, Moscow, RUSSIA [1]; Institute of Bioelementology at Orenburg State University, Orenburg, RUSSIA [2]
P-10 6.07 SEX DEPENDENT PECULIARITIES OF SOME IMPORTANT CHEMICAL ELEMENT RATIOS IN HAIR OF SCHOOLCHILDREN. Andrei Grabeklis [1], Vasily Demidov [1], Svetlana Notova* [2]. Center for Biotic Medicine, P.O. Box 56, Moscow 125047, RUSSIA [1]; Institute of Bioelementology at Orenburg State University, Orenburg, RUSSIA [2]
P-11 6.08 HIGH RESOLUTION ICP-MS – A USEFUL TOOL TO STUDY MANGANESE ACCUMULATION INDUCED BY IRON DEFICIENCY. Tore Syversen* [1], Stephanie J. Garcia [3], Kristin Gellein [2], Eiliv Steinnes [2], Trond P. Flaten [2], Michael Aschner [3]. Department of Neuroscience [1] and Department of Chemistry [2], Norwegian University of Science and Technology (NTNU), MTFS, N-7489 Trondheim, NORWAY; Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA [3]
P-12 LB.26 EFFECT OF MICRONUTRIENT SUPPLEMENTATION ON THE GROWTH OF PRESCHOOL CHILDREN IN CHINA. Yang Yuexin*, Han Junhua, Shao Xiaoping, He Mei, Bian Lihua, Wang Zhu. Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, 29 NanWei Road, Beijing 100050, CHINA
Category 7: Trace Elements and Infectious and Immune Disorders
P-13 7.01 INHIBITORY ACTIVITY OF STAPHYLOCOCCUS AUREUS IN MILK FROM COWS FED SLENIUM-SUPPLEMENTED AND SELENIUM DEFICIENT DIETS. Faik Atroshi*, Marge Malbe, Martti Attila, Tuomas Westermarck, Hannu Saloniemi. Dept. Vet. Clinical Science, Pharmacology & Toxicology, PL 57, 00014 Helsinki University, FINLAND
P-14 7.02 ZINC PREVENTS CERAMIDE INDUCED JNK ACTIVATION, FAS LIGAND EXPRESSION AND CASPASE-3 DEPENDENT APOPTOSIS IN CD4+ T LYMPHOCYTES. S. Karandikar [1], S. Joshi-Barve [2], C. J. McClain [2] and S. Barve* [2]. University of Louisville, Department of Microbiology and Immunology [1] and Department of Internal Medicine [2], Louisville, KY 40202
P-15 7.04 THE EFFECTS OF ULTRASOUND ON SYNOVIAL FLUID ZINC LEVEL IN PATIENTS WITH RHEUMATOID ARTHRITIS. Ethem Akçil [1], Bulent Seçkin [2], Ahmet Ergün [3], Rezan Hatungil* [4]. Dept.Pathophysiology, Faculty of Medicine, Ankara Üniversity, Ankara [1]; Dept. Physical Medicine and Rehabilitation, Faculty of Medicine, Ankara University, Ankara [2]; Dept. Physiology, Faculty of Medicine, Ankara University. Ankara [3]; Dept.physiology, Faculty of Medicine, Mersin University,Mersin, [4],TURKEY
P-16 7.05 LOCALIZATION OF TRACE METALS IN THE CEREBELLA OF SCRAPIE INFECTED HAMSTERS. Christopher J. Johnson*[1,2], Valerie B. Hoefert[1,2], Bradley H. Frazer [3], Joel A. Pedersen[4,5], Debbie McKenzie [2], Gelsomina De Stasio [3], Judd M. Aiken[1,2]. University of Wisconsin-Madison: Program in Cellular & Molecular Biology [1], Department of Animal Health & Biomedical Sciences, 1656 Linden Dr, Madison WI 53705, USA [2]; Synchrotron Radiation Center, Stoughton, WI 53589, USA [3]; Department of Soil Science, Madison WI 53705, USA [4]; Program in Molecular and Environmental Toxicology [5]
P-17 7.06 REDINTEGRATION EFFECT IN NATURAL KILLER CELL ACITIVITY OF ATHLETE WITH IMMUNOSUPRESSION BY TRACE ELEMENT. Mieko Kimura* and Takahisa Takeda. Takeda Research Institute of Life Science & Preventive Medicine, Kyoto Research Park 134 tyudoji-minamimati Simogyoku 600-8813, Kyoto, JAPAN
P-18 7.07 IRON DEFICIENCY REDUCES INTERLEUKIN-4 SECRETION IN MICE. Solo Kuvibidila*, Maria Velez, Rene Gardner, Lolie Yu, David Ode, Raj P Warrier. Pediatrics, LSU Health Sciences Center & the Research Institute for Children, New Orleans, LA 70112, USA
P-19 7.08 EFFECT OF ZINC DEFICIENCY ON NEUTROPHIL TRASMIGRATION AND JUNCTION PROTEINS DISTRIBUTION IN CACO-2 CELLS. Alberto Finamore [1], Mara Massimi [2], Laura Conti Devirgiliis [2], Elena Mengheri* [1]. Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione, Roma, ITALY [1]; Dip. Biologia di Base ed Applicata, Università. dell’Aquila, L’Aquila, ITALY [2]
P-20 7.09 ATTENUATION OF BERYLLIUM INDUCED TOXICITY THROUGH TIFERRON ALONG WITH PROPOLIS AS NUTRITONAL SUPPLEMENTATION IN RATS. Satendra Kumar Nirala* [1], R. Mathur [1], A. Mathur [2]. SOS in Zoology, Jiwaji University, Gwalior-474011, INDIA [1]; Naveen Girls College, 17-A, New Saket Nagar, Gwalior-474002, INDIA [2]
P-21 7.10 IMMUNE RESPONSE AND ZINC STATUS IN OLDER SUBJECTS. A.Finamore [1], D. Panno [1], V.C. Jewell [2], C. Hodkinson [2], J. M. O’ Connor [2], J. Wallace [2], S. Strain* [2], E. Mengheri [1]. Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione, Via Ardeatina, 546, 00178 Roma, ITALY [1]; Northern Ireland Centre for Food and Health, University of Ulster, Cromore Road, Coleraine, BT52 1SA, NORTHERN IRELAND [2]
P-22 7.11 REDUCED PRODUCTION OF IMMUNOREGULATORY CYTOKINES IN ZINC AND VITAMIN A DEFICIENT INDONESIAN INFANTS. Frank T. Wieringa* [1], Marjoleine A. Dijkhuizen [1], Muhilal [2], Johanna vd Ven-Jongekrijg [1], Clive E. West [3], Jos W.M. van der Meer [1]. Univ. Med. Center Nijmegen, Dept. Int. Med. PO Box 9101, 6500 HB, NETHERLANDS [1]; Nutr Res Dev Center Bogor, INDONESIA [2]; Dept Human Nutr, Univ Wageningen, NETHERLANDS [3]
P-23 LB.24 SERUM ZINC, SELENIUM, COPPER, AND CERULOPLASMIN IN PRIEST SUBJECTS. Duangkamol Viroonudomphol* [1], Rachaneekorn Mingkhawn [1], Anchlee Mahaisiriyodom [2], Pak Sadomthian [1], Nattaporn Korchasri [1], Siriporn Sangcakul [1]. Central Equipment Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand [1]; Dept. Pathology, Priest Hospital, Bangkok 10400, THAILAND [2]
P-24 LB.13 LANTHANUM INDUCED REPRODUCTIVE TOXICITY AND ITS REGULATION. Asha Mathur* [1], and Tripti Sharma [2] KRG College, Kampoo, Gwalior, INDIA [1]; Department of Zoology, Govt. Science College, Gwalior, INDIA [2]
P-25 LB.08 ZINC INTAKE, STUNTED GROWTH AND THE INCIDENCE OF PNEUMONIA IN CHILDREN UNDER 5 YEARS OLD IN UPPER NORTHERN THAILAND. Songwut Hutamai*[1], Poonlarp Chantavichitwong [2], Surasing Visrutaratna [2], Sakda Pruenglampoo [3], Angkarb Boonyoi[4], Nittaya Rawungpan [1], Angkana Theerasawasde [1], Jaroensri Sae-tung [1], Posri Leelapat [3], Tawatchai kumrin [3], Boonlure Pruenglampoo [3] and Emorn Wasantwisut [5]. The Office of Disease Prevention and Control, 10 Chiang Mai [1]; Chiang Mai Provincial Health Office [2]; Research Institute for Health Sciences, Chiang Mai University [3]; Dept. Statistics, Faculty of Sciences, Chiang Mai University [4]; Institute of Nutrition, Mahidol University, Nakhon Pathom, THAILAND [5]
P-26 LB.03 ASSESSING THE ANTIOXIDANT STATUS IN HIV PATIENTS. Guntars Selga [1], Andrejs Skesters [1], Melita Sauka [1], A.Silova[1], Tuomas Westermarck[2], and Faik Atroshi[3]. Riga Stradins University, LATVIA [1]; Rinnekoti Research Center, Espoo, 02980 [2]; Pharmacology & Toxicology, ELTDK, PL 57, 00014 Helsinki University, FINLAND [3]
P-27 LB.04 SEVERE PSORIASIS PATIENT TREATED WITH SELENIUM, ZINC, and VITAMIN E. Tuomas Westermack [1], Erland Johansson, Erkki Antila [2], Faik Atroshi [3]. Rinnekoti Research Center, Espoo, FI-02980 [1]; Med Sport Clinic, Mehiläinen Clinic, Helsinki; Pharmacology & Toxicology, ELTDK, PL 57, 00014 Helsinki University, FINLAND [3]
Category 8: Trace Element Molecular Nutrition for the Clinician
P-28 8.01 FUMONISIN B1 DAMAGE DNA IN RAT LIVER. SELENIUM AND OTHER ANTIOXIDANTS INHIBIT FUMONISIN TOXICITY. Faik Atroshi*, Aldo Rizzo, Terhi Ali-Vehmas, Tuomas Westermarck. Dept. Vet. Clinical Science, Pharmacology & Toxicology, PL 57, 00014 Helsinki University, FINLAND
P-29 8.02 KISS AND RUN: THE ROUTE OF IRON FROM ENDOSOMES TO MITOCHONDRIA CAN BYPASS THE CYTOSOL IN HEMOGLOBIN-PRODUCING CELLS. Alex Sheftel [1], An-Sheng Zhang[1,2], Orian Shirihai [3], Prem Ponka* [1]. Dept. of Physiology and Medicine, McGill University, Montreal, QC, Canada [1]; Dept. of Cellular and Developmental Biology, Oregon Health Sciences University, Portland, OR, USA [2]; Biocurrents Research Center, Marine Biological Institute, Woods Hole, MA, USA [3]
P-30 LB.10 EFFECT OF ZINC ON THE TRANSPORT FUNCTION OF ERYTHROCYTE MEMBRANE. Han Jun-hua*，Yang Yue-xin, Men Jian-hua, Wang Zhu. Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, 29 NanWei Road, Beijing 100050, CHINA
P-31 LB.05 STUDY OF THE EFFECT OF IRON THERAPY ON COPPER STATUS IN WOMEN WITH IRON DEFICIENCY ANEMIA IN IRAN UNIVERSITY OF MEDICAL SIENCES’ HOSPITALS. Shahryar Egtesadi*, Katayoon Poorvali, and Zia Mazhari. Iran University of Medical Sciences, School of Public Health, Department of Nutrition, Tehran, IRAN
P-32 LB.20 MITOCHONDRIAL ENZYME NIFS CONTRIBUTED TO POSTTRANSCRIPTIONAL REGULATION OF ACONITASE IN IRON-DEFICIENT RAT SKELETAL MUSCLE. Yih Fong Liew, and Ning-Sing Shaw*. Institute of Microbiology and Biochemistry, National Taiwan University, Taipei 10673, Taiwan, REPUBLIC OF CHINA
14:30-17:30 Three Concurrent Sessions (Symposia A and B; Minisymposium #1)
Symposium A--Ballroom I
Infectious Disease and Trace Elements
Chair: Robert Black
Purpose of session: Trace element nutrition profoundly affects immunity. Randomized controlled trials in infants of India, Bangladesh, and Pakistan have shown that addition of zinc to oral rehydration fluids given for diarrhea significantly reduce morbidity and death and decrease the co-occurrence of pneumonia. It is anticipated this treatment will save millions of lives. Application of knowledge of the essentiality of zinc for immunity has also decreased morbidity in infants infected with falciparum malaria. Extension of this knowledge to treatment of AIDS, tuberculosis and other infectious diseases has important effects on morbidity. Discovery of effects of selenium deficiency in the host (animals or humans) on viral genome is a significant advance in understanding of mechanisms for emergence of new strains of pathogenic viruses. Experiments in mice made Se deficient to replicate the human disease Keshan’s Myocardiopathy revealed that a benign strain of Coxsackie virus changed to a pathogenic strain that would subsequently kill a normal mouse. These findings suggest that selenium nutrition of host animals might have played a role in emergence of other diseases such as new strains of influenza, Ebola and AIDS virus. A summary of the many new findings related to essential mineral deficiencies as they affect immune function will provide information useful in establishing or updating relevant public health policies.
14:30 "Zinc childhood infectious diseases," Robert Black
15:00 "Iron supplementation and risk of infectious disease," Sunil Sazawal
15:30 "Trace elements and HIV infections," Henrik Friis
16:00 "Trace elements and tuberculosis," Carlton Evans
16:30 Delegate Tea Break
Symposium B--Ballroom II
The Link Between Zinc and Redox Metabolism and its Significance for Chronic Disease
Chair: Wolfgang Maret
Purpose of session: There is emerging evidence for the concept that zinc metabolism is compromised in any disease accompanied by oxidative stress. Reactive species formed under oxidative stress release zinc from proteins, thereby interfering with both cellular signaling and generation of cellular energy. The effect of nitric oxide (NO) signaling on cellular zinc homeostasis has received particular attention in this regard. If oxidative stress is sustained over a long period of time "local zinc deficiencies" may develop in affected tissues and drastically alter their physiology. On the other hand, zinc is considered an antioxidant that affects, and perhaps controls, redox metabolism. Zinc deficiency elicits oxidative stress, and thus exacerbates the deficiency. It is now becoming clear that this action is indirect as zinc itself is redox-inert. Zinc is necessary for enzymes such as superoxide dismutase and for the induction of thiol-reducing capacity in proteins such as metallothionein and in compounds such as glutathione, which jointly determine the antioxidant potential of a cell. The symposium brings together experts who will summarize recent findings that lend additional support for a link between zinc and redox metabolism.
14:30 "Introduction to the symposium: The link between zinc and redox metabolism," Wolfgang Maret
15:00 "Zinc and cell cycle control in the cancer cell," Paul Smith
15:30 "Oxidative stress in zinc deficiency: Molecular mechanisms and signals," Carl Keen
16:00 "Selenium restores increased free zinc concentration in streptozotocin-induced diabetic rat cardiomyocytes," Belma Turan
16:30 Delegate Tea Break
Minisymposium 1--Rattanakosin
Chair: John Beattie
Co-Chair: Leslie Woodhouse
Minisymposium : Trace Elements and Diabetes, Cardiovascular Diseases, and Fetal Development
Category 3: Trace Elements and Cardiovascular and Pulmonary Diseases
14:30 3.01 ZINC DEFICIENCY INDUCED CHANGES IN THE EXPRESSION OF VASCULAR CELL PROTEINS USING PROTEOMICS. John H. Beattie* [1], Soo-Lim Lee [2], and In-Sook Kwun [2]. Division of Cellular Integrity, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UNITED KINGDOM [1]; Department of Food Science and Nutrition, Andong National University, Andong, Kyungpook 760-749, SOUTH KOREA [2]
Category 4: Trace Elements and Diabetes Mellitus, Metabolic Syndrome X, and Obesity
14:45 4.01 STRESS INDUCED CHANGES IN TISSUE CHROMIUM, COPPER, AND ZINC ARE NOT CORRELATED WITH CHANGES IN INSULIN REALATED VARIABLES FOLLOWING THERMIC AGGRESSION. R. A. Anderson* [1], D. Aguay [3], N. A Bryden [1], C. Sandre [3], Y. Chancerelle [2], M. M. Polansky [1], and A M. Roussel [3]. Beltsville Nutrition Center, Beltsville, MD, USA [1]; Centre de Recherche des Arme's [2] ; J Fourier Univ, La Tronche, FRANCE [3]
15:00 4.05 SERUM SELENIUM AND GLUTATHIONE PEROXIDASE STATUS IN METABOLIC SYNDROME AND OBESITY; EFFECTS OF DIETARY SELENIUM AND STATIN THERAPY. Majid Ghayour-Mobarhan*, Andrew Taylor, David Lamb, Susan New, Callum Livingstone, Tim Wang, and Gordon Ferns. University of Surrey, Guildford, GU2 7XH, UNITED KINGDOM
15:15 4.07 DIETARY BORON REDUCES SERUM INSULIN CONCENTRATIONS REGARDLESS OF VITAMIN D STATUS IN RATS. Yeong Rhee* [1], Curtiss Hunt [2], Joseph Idso [2]. Dept. Health, Nutrition and Exercise Sciences, North Dakota State University, Fargo, ND 58105, USA [1]; Grand Forks Human Nutrition Research Center, USDA/Agricultural Research Service, P.O. Box 9034, Grand Forks, ND 58202, USA [2]
15:30 4.08 STRUCTURE-ACTIVITY RELATIONSHIP OF VANADYL-PICOLINATE COMPLEXES WITH ANITIDIABETIC ACTIVITY. Hiromu Sakurai*, Yusuke Adachi, Kojiroh Tayama, Naoko Yasumatsu and Hiroyuki Yasui. Dep. Anal. Bioinorg. Chem., Kyoto Pharm. University, Kyoto 607-8414, JAPAN
15:45 4.10 PLASMA LEVELS OF ZINC WITH LEPTIN, GLUCOSE AND WEIGHT AS PREDICTORS OF CIRCULATING GHRELIN LEVELS IN BABOONS. Saroja Voruganti* [1], Jeanne Freeland-Graves [1], Elizabeth Tejero [2], Michael Proffitt[1,2], Guowen Cai [2], Shelley Cole [2], and Anthony Comuzzie[2,3]. Division of Nutritional Sciences, A2700, The University of Texas at Austin, Austin, TX 78712, USA [1]; Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX, USA [2]; Southwest National Primate Research Center, San Antonio, TX, USA [3]
16:00 4.12 EFFECT OF SHORT-TERM WEIGHT LOSS ON ZINC STATUS IN OVERWEIGHT ADULTS CONSUMING HYPOCALORIC DIETS WITH HIGH DAIRY INTAKE, LOW DAIRY INTAKE OR CALCIUM SUPPLEMENTATION. Leslie R Woodhouse* [1], Erik R Gertz [1], Timothy L Radak [1], Dorothy Teegarden [2], Michael B Zemel [3], Marta D Van Loan [1]. USDA ARS WHNRC, UCD, Davis, CA 95616, USA [1]; Dept. of Foods and Nutrition, Purdue U, West Lafayette, IN 47907, USA [2]; Dept. of Nutrition, U of Tennessee, Knoxville, TN 37996, USA [3]
Category 6: Trace Elements and Fetal Development and Pediatric Disorders
16:15 6.02 A MULTI-COUNTRY TRIAL ON IRON AND ZINC SUPPLEMENTATION IN INFANTS: INTERACTIONS AND EFFECTS ON MICRONUTRIENT STATUS AND GROWTH. SEAMTIZI study group: Frank T. Wieringa* [1], Jacques Berger[2,5], Marjoleine A. Dijkhuizen [1], Adi Hidayat [4], Nguyen X. Ninh [5], Budi Utomo [3], Emorn Wasantwisut [6], and Pattanee Winichagoon [6]. SEAMTIZI: South-East Asia Multi-country Trial on Iron and Zinc supplementation in Infants Study Group. Univ. Med. Center Nijmegen, Dept. Int. Med. PO Box 9101, 6500 HB, NETHERLANDS [1]; Inst. Rech. Dev., Lab. Nutr. Trop., Montpellier, FRANCE [2] Univ. Indonesia [3] and Univ. Trisakti [4], Jakarta, INDONESIA; Nat. Inst. Nutr., Hanoi, VIETNAM [5]; Inst. Nutr., Mahidol Univ. Bangkok, THAILAND [6]
16:30 Delegate Tea Break
17:00 6.03 ZINC ENHANCES THE EFFECTIVENESS OF ß-CAROTENE SUPPLEMENTATION DURING PREGNANCY IN IMPROVING VITAMIN A STATUS IN BOTH MOTHERS AND INFANTS. Marjoleine A. Dijkhuizen* [1], Frank T. Wieringa [1], Clive E. West [2], Muhilal [3]. Univ. Med. Center Nijmegen, Dept. Int. Med. PO Box 9101, 6500 HB, NETHERLANDS [1]; Dept Human Nutr, Univ Wageningen, NETHERLANDS [2]; Nutr Res Dev Center Bogor, INDONESIA [3]
17:15 6.05 ZINC AND IODINE STATUS OF SCHOOLS CHILDREN FROM RURAL NORTH EAST THAILAND. Sueppong Gowachirapant* [1], T Pongcharoen [1], A Boonpraderm [1], R Cook [2], R Gibson [2], P Winichagoon [1]. Institute of Nutrition, Mahidol University, Salaya, Thailand [1]; Department of Human Nutrition, University of Otago, NEW ZEALAND [2].
17:30 6.09 EFFICIENT STRATEGY FOR HAPLOTYPE ANALYSIS OF WILSON DISEASE USING NEW POLYMORPHIC SHORT TANDEM REPEATS IN FRENCH FAMILIES. Muriel Bost* [1,2], Giuseppe Sanna [3], Laetitia Boutrand [3], Philippe Latour [2], Antoon Vandenberghe [2,3]. Trace Element - Institute for UNESCO [1]; Debrousse Hosp., Neurogenetics [2]; ISPB Lyon, Human Molecular Genetics, FRANCE [3]
17:30-18:30 Pimai ISTERH Board Meeting 1
18:00 Monday posters removed from boards in Ballroom III
___________________________________________________
TUESDAY MORNING, November 96:30
7:00 Ancillary Function Breakfast
Scientific Committee on Toxicology of Metals under International Commission on Occupational Health (SCTM/ICOH). Contact Dr. Monica Nordberg during the conference for more information.
7:30 Main Entrance of Grand Ballroom
Registration
7:30 Ante Room (next to Ballroom III)
Speaker Ready Room
8:00 Foyer (in front of the Grand Ballroom)
Commercial Exhibits
9:00-12:00 Ballroom I and II
Plenary Session #2: Improving absorption and bioavailability to address iron deficiency
Chair: Janet Hunt
Purpose of Session: Deficiency of iron and the associated anemia, which adversely influence cognitive and immune function and diminish work capacity, affect more than 3.5 billion people worldwide, with greater prevalence in developing countries. The World Health Organization lists iron deficiency among the ten top health risks, and classifies iron deficiency anemia as a priority action area. Iron deficiency is estimated to cost (U.S.) $5 billion annually in South Asia alone because of impaired human productivity. This symposium will honor Professor Leif Hallberg with the Raulin Award for his extensive contributions to understanding iron deficiency, requirements and bioavailability. Recent results from testing of dietary iron supplementation and food fortification strategies will be reviewed, including human adaptation to dietary iron intake and bioavailability, efficacy of dietary tactics such as increasing ascorbic acid intakes, and the value of fortification sources such as NaFeEDA, chelated iron, and elemental iron powders. The symposium will also include the latest information from our rapidly expanding knowledge of the molecular control of iron absorption, including specific transport proteins such as Dcytb, DMT1, and Ireg1 as well as the role of the hepatic peptide hepcidin in controlling iron absorption and body iron content.
9:00 Keynote and RAULIN AWARD lecture: "Nutritional iron deficiency – early perspective & present applications," Leif Hallberg (ISTERH acknowledges the generous support from Labcatal)
10:00 "Combating iron deficiency - supplementation, fortification, and dietary tactics," Janet Hunt
10:45 Delegate Tea Break
11:15 "The mechanism and regulation of intestinal iron absorption," Greg Anderson
TUESDAY AFTERNOON
12:30 Boarding buses at the Shangri-La Hotel for excursion to Ayudhaya, the Old Capitol.
Box lunch covered in registration fee; please inform the Secretariat whether you plan to participate)
18:00 Return to Shangri-La Hotel
Remainder of evening free
___________________________________________________
WEDNESDAY MORNING, November 106:30
7:30 Main Entrance of Grand Ballroom
Registration
7:30 Ante Room (next to Ballroom III)
Speaker Ready Room
8:00 Ballroom III
Wednesday posters open. Presentation time: 13:30-14:30
8:00 Foyer (in front of the Grand Ballroom)
Commercial Exhibits
8:30-12:00 Ballroom I and II
Plenary Session #3: Zinc nutrition and diseases of the brain
Chair: Christopher Frederickson
Purpose of Session: Zinc is essential for brain growth, development, and function. At the molecular level it is essential for nucleic acid and protein synthesis. Through binding to thousands of proteins, zinc stabilizes structure and mediates many aspects of metabolism. Because all DNA repair enzymes require zinc for activity, one theory of Alzheimer’s Dementia (AD) pathogenesis suggests that zinc deficiency decreases DNA repair with the result that neurons accumulate DNA damage which disrupts homeostatic mechanisms and ultimately leads to neuronal death. Consideration of zinc-dependent DNA repair and effects of low repair will provide a basis for consideration of possible mechanisms whereby the zinc and copper chelator clioquinol is efficacious for experimental AD in mice and is potentially beneficial for human AD. Large amounts of zinc suddenly released into the brain milieu are toxic. Mechanisms of the phenomenon are of high interest because massive release of zinc occurs with strokes and trauma to the brain. Zinc is also highly efficacious for prevention of brain injury from copper overload as occurs in the genetic disease described by Wilson more than 100 years ago. Prior to the discovery of the efficacy of zinc, other forms of therapy were associated with many side effects, some of which were incapacitating. Mechanisms of zinc actions in treatment of Wilson’s disease are of high interest because they shed light on interactions of zinc and copper that are applicable in understanding other diseases including cardiovascular disease. The symposium will summarize the rapid advancements made in our knowledge of the roles of zinc in brain growth, development, and function.
8:30 "Somatic and synaptic release of zinc in health and disease," Christopher Frederickson
9:05 "Recovery from copper-induced brain damage in Wilson’s disease using zinc therapy," George Brewer
9:40 "Oxidation, biometals and Alzheimer's disease," Ashley Bush
10:15 Delegate Tea Break
10:45 "Emerging role for endogenous zinc in neurological diseases," Jae-Young Koh
11:20 "Neuronal Zn2+: Sources of intracellular accumulation and effects on mitochondrial function," John Weiss
12:00-13:30
Delegate Lunch (on own)
12:00-13:30 Pimai
Journal of Trace Elements in Experimental Medicine (JTEEM) Board Meeting.
WEDNESDAY AFTERNOON
13:30-14:30 Ballroom III
13:30-14:30 Poster Session 2
Category 1: Bioavailability of Trace Elements and Dietary Patterns
P-1 1.02 MACRO- AND TRACE ELEMENTS IN PLASMA OF INJURED MILITARIES. Igor Bakulin*[1,2], Vladislav Novozhenov [1], Margarita Skalnaya [2]. Municipal clinical hospital 29, Moscow, RUSSIA [1]; Russian Society of Trace Elements in Medicine (RUSTEM), Moscow, RUSSIA [2]
P-2 1.03 INTERACTION BETWEEN IRON, IODINE AND ZINC STATUS IN A REGIONAL SAMPLE OF MOROCCAN WOMEN. Rekia Belahsen* and Imane Bahbouhi. Chouaib Doukkali University, Training and Research Unit on Food Sciences, Laboratory of Physiology Applied to Nutrition and Feeding, School of Sciences, El Jadida 24000, MOROCCO
P-3 1.05 TRACE ELEMENTS CONCENTRATION IN HUMAN NAILS USING ATOMIC ABSORPTION SPECTROMETRY. F. A. El-Amri* [1] and R. I. Damja [2] . United Arab Emirate Universits,Faculty of Scienc Chem.Dept P.O.Box 17551, Al-Ain, UNITED ARAB EMIRATES [1]; University of Al-Fathi Faculty of Science Chem.Dept. P.O.Box 13361 Tripoli, LIBYA [2]
P-4 1.08 EFFECT OF CARNOSINE ON THE ABSORPTION OF IRON AND VARIOUS TRACE ELEMENTS IN RATS. Kaori Igarashi* [1], Rieko Hirunuma [1], Hiromitsu Haba [1], Shuichi Kimura[1,2], Shuichi Enomoto [1] . Cyclotron Center, RIKEN, Wako Saitama, 351-0198, JAPAN [1]; Graduate School of Human Life Sciences, Showa Women’s University, Setagaya Tokyo, 154-8533, JAPAN [2]
P-5 1.09 STUDY OF INTERELEMENTAL EFFECTS OF MINERAL BIOAVAILABILITY USING IN VITRO CONTINUOUS-FLOW DIALYSIS WITH INDUCTIVELY COUPLED PLASMA OPTICAL EMISSION SPECTROMETRIC METHOD. Kunchit Judprasong*, Mathuros Ornthai, Sopon Purawatt, Atitaya Siripinyanond, and Juwadee Shiowatana. Department of Chemistry, Faculty of Science, Mahidol University, Rama VI Rd., Bangkok, 10400, THAILAND
P-6 1.10 MULTIELEMENT HAIR PROFILE OF PROFESSIONAL FOOTBALL PLAYERS. Anatoly Skalny [1], Artem Katulin*[1,2]. Russian Society of Trace Elements in Medicine, P.O. Box 56, Moscow, 125047, Russia [1]; Moscow Scientific-Practical Center of Sport Medicine, Moscow, Russia [2]
P-7 1.12 EFFECT OF ZINC AND IRON DEFICIENCY ON RECTAL TEMPERATURE AND IRON PARAMETERS IN RATS. Aki Konomi*, Katsuhiko Yokoi. Department of Human Nutrition, Seitoku University Graduate School, 550 Jwase, Matsudo, Chiba 271-8555, JAPAN
P-8 1.13 BIOAVAILABLE IRON IN SELECTED SPECIES OF GRASSHOPPERS. Virginia Melo*, Maritza Garcìa, Claudia Maass, José Salas, Norma Nogueda. Universidad Autónoma Metropolitana, Xochimilco, MEXICO
P-9 1.33 EDIBLE INSECTS: SELENIUM SOURCE FOR MEXICAN RURAL COMMUNITIES. Virginia Melo*, Maritza García, Claudia Maass, Rosa Casillas, Norma Nogueda. Universidad Autónoma Metropolitana, Xochimilco, MEXICO
P-101.14 INFLUENCES ON BIOCHEMICAL AND SEXUAL FUNCTIONS OF ZINC SUPPLEMENTATION IN MEN. Tomohide Koizumi [1], Kanako Hattori [1], Kazuya Murakami* [1], Aki Konomi [2], Katsuhiko Yokoi [2] . Tomita Pharmaceutical Co., Ltd., Akinokami, Seto-cho, Naruto, Tokushima 771-0360, JAPAN [1]; Human Nutrition, Seitoku University Graduate School, Iwase, Matsudo 271-8555, Chiba, JAPAN [2]
P-11 1.16 DIETARY AND BIOCHEMICAL IRON STATUS OF STUNTED AND NON-STUNTED SCHOOL CHILDREN IN NE THAILAND. Tippawan Pongcharoen* [1], A. Boonpraderm [1], S. Gorwachirapan [1], R. Cook [2], R. Gibson [2], P. Egkantrong [1] P. Winichagoon [1] . Institute of Nutrition, Mahidol University, Salaya, THAILAND [1]; Department of Human Nutrition, University of Otago, NEW ZEALAND [2]
P-12 1.19 CHARACTERIZATION OF MOLECULAR WEIGHT AND SIZE DISTRIBUTION OF ESSENTIAL ELEMENTS IN MILK USING FIELD-FLOW FRACTIONATION-INDUCTIVELY COUPLED PLASMA SPECTROMETRY. Usarat Kamtabtim, Sudarat Saeseaw*, Atitaya Siripinyanond, and Juwadee Shiowatana. Department of Chemistry, Mahidol University, Rama VI Rd., Bangkok 10400, THAILAND
P-13 1.21 DIETARY FACTORS AFFECTING TRACE ELEMENT BIOAVAILIBILITY FROM HUMAN MILK, COW’S MILK AND INFANT FORMULAS IN MOROCCO. F. Zaida [1], N. Lekouch [1], D. Bouglé [2], F. Bureau [2], P. Arhon [2], and A. Sedki* [1]. Laboratory of Ectoxicology, Faculty of Science Semlalia, Marrakech, MOROCCO [1]; Laboratory of Digestive and Nutritional Physiology, CHU de Caen, FRANCE [2]
P-14 1.22 MOBILE FORMS OF ZINC, COPPER AND MANGANESE IN ARABLE SOILS FROM VARIOUS RUSSIAN REGIONS AND CHILDREN'S HAIR CONTENT. Margarita Skalnaya* [1], Viktor Tutelian [2] . Russian Society of Trace Elements in Medicine (RUSTEM), Moscow, Russia [1]; Institute of Nutrition, Russian Academy of Medical Sciences, Moscow, Russia [2]
P-15 1.23 MACRO- AND TRACE ELEMENTS CONTENT OF TEMPORAL AND OCCIPITAL HAIR SAMPLES. Vladislav Tkachev [1], Vladimir Skalny*[1,2], Evgeny Serebryansky [1]. Russian Society of Trace Elements in Medicine (RUSTEM), Moscow, RUSSIA [1]; Institute of Bioelementology at Orenburg State University, Orenburg, RUSSIA [2]
P-16 1.24 ESTIMATION OF CALCIUM IN VITRO BIOAVAILABILITY OF VEGETABLES USING A NOVEL CONTINUOUS-FLOW DIALYSIS SYSTEM. Sutthinun Taebunpakul*, Upsorn Sottimai, and Juwadee Shiowatana. Department of Chemistry, Faculty of Science, Mahidol University, Rama VI Rd., Bangkok 10400, THAILAND
P-17 1.25 CHROMIUM CONCENTRATIONS IN HUMAN PLASMA DURING HOME PARENTERAL NUTRITION AND INFUSUION PRODUCTS IN JAPAN. Yoji Takagi* [1], Takeo Kikuchi [2], Daisuke Ikeda [2], Seiji Nishida [2], Makoto Sato [2]. Dept. of Maternal and Child Nursing, School of Allied Health Sciences, Faculty of Med., Osaka Univ., JAPAN [1], Pharm. Research Center, Nipro Co., JAPAN [2]
P-18 1.26 BLOOD CONCENTRATIONS OF ESSENTIAL TRACE ELEMENTS IN PATIENTS RECEIVING HOME PARENTERAL NUTRITION IN JAPAN. Kiyomi Tanaka*[1], Kinya Sando[1], Masafumi Wasa[1], Masahiro Fukuzawa[1], Yoji Takagi[2]. Dept. Pediatric Surgery, Graduate School of Medicine, Faculty of Medicine, Osaka University, Suita, Osaka, PO Box 565-0871, JAPAN [1], Dept. Maternal and Pediatric Nursing, School of Allied Health Sciences, Faculty of Medicine, Osaka University, Suita, Osaka, PO Box 565-0871, JAPAN [2]
P-19 1.27 IRON ABSORPTION BY HUMAN SUBJECTS FROM DIFFERENT IRON FORTIFICATION COMPOUNDS ADDED TO THAI FISH SAUCE. Siriporn Tuntipopipat* [1], Thomas Walczyk [2], Christophe Zeder [2], Emorn Wasantwisut [1], and Richard F Hurrell [2]. Institute of Nutrition, Mahidol University, Putthamonthon, Nakhon Pathom, THAILAND [1]; Laboratory of Human Nutrition, Swiss Federal, Institute of Technology (ETH) Zurich, Rüschlikon, SWITZERLAND [2]
P-20 1.31 MATHEMATICAL APPROACH FOR ESTIMATING IRON REQUIREMENTS FROM POPULATION DATA . Katsuhiko Yokoi*. Department of Human Nutrition, Seitoku University Graduate School, Matsudo, Chiba 271-8555, JAPAN
P-21 1.32 IRON ABSORPTION IN A MINERAL SUPPLEMENTED OAT-BASED DRINK. Huan-Mei Zhang* [1], Gunilla Önning [1], Rickard Öste [2], Elisabeth Gramatkovski [3], Lena Hulthen [3]. Biomedical Nutrition, Lund University, Chemical Center, P.O. Box 124, SE22100 Lund, SWEDEN [1]; CEBA Foods AB, Scheelevagen 18, SE22363 Lund, SWEDEN [2]; Dept. Clinical Nutrition, Sahlgrenska Academy at Göteborg University, SE41345 Göteborg, SWEDEN [3]
P-22 LB.20 AN ACTION RESEARCH TO CONTROL AND PREVENT IRON DEFICIENCY AND IRON DEFICIENCY ANEMIA IN WOMEN OF REPRODUCTIVE AGE IN A FACTORY IN THAILAND. Utoomporn Sittisingh*[1], Marc Van der Putten [2], Sakorn Dhanamitta [3], Sangsom Sinawat[1]. Nutrition Division, Dept. of Health, MOPH, Tiwanond Road, Muang District Nonthaburi 11000, THAILAND[1]; College of Public Health, Chulalongkorn University, 10th Floor, Institute Building3, Soi Chulalongkorn 62, Phyathai Road, Patumwan, Bangkok 10330, THAILAND[2]; Institute of Nutrition, Mahidol University, 25/25 Phutthamonthon Sai 4 Road, Salaya, Nakorn Pathom 73170, THAILAND[3]
P-23 LB.10 ZINC AND CALCIUM BIOAVAILABILITY OF RICE AND FERMENTED SOYBEAN. Posri Leelapat*[1], Sakda Pruenglampoo[1], Songwut Hutamai[2], Poonlarp Chantavichitwong[3], Surasing Visrutaratna[3], Angkarb Boonyoi[4], Nittaya Rawungpan[2], Angkana Theerasawasde[2], Jaroensri Sae-tung[2], Tawatchai kumrin[1], Boonlure Pruenglampoo[1] and Emorn Wasantwisut [5]. Research Institute for Health Sciences, Chiang Mai University[1]; The office of Disease Prevention and Control, 10 Chiang Mai [2]; Chiang Mai Provincial Health Office[3]; Department of Statistics, Faculty of Sciences, Chiang Mai University[4]; Institute of Nutrition, Mahidol University, Nakhon Pathom, THAILAND[5]
P-24 LB.11 CHELATION THERAPY AGAINST LANTHANUM INDUCED TOXICITY. Asha Mathur; Govt. K.R.G. Autonomous College, Gwalior-474002, INDIA
P-25 LB.2 MASSIVE HEPATOCYTE DAMAGE AND ITS PREVENTION BY BORON INVOLVES MODULATION OF PEROXIDE METABOLISM PATHWAYS. Shakir Ali[1], M. Abdulla[2]. Department of Biochemistry, Faculty of Science, Jamia Hamdard, Hamdard Nagar, New Delhi ˆ 11 00 62, INDIA[1]; 2 Trace Element Institute for UNESCO, Lyon, FRANCE[2]
Category 3: Trace Elements and Cardiovascular and Pulmonary Diseases
P-26 3.03 SELENIUM SUPPLEMENTATION AND BLOOD HEMORHEOLOGICAL CHANGE. Hiroshi Koyama [1], Kaori Miyazaki [1], Misa Nara [2], Masami Murakami [2]. Dept. Public Health [1]; Dept. Clinical Laboratory Medicine [2], Gunma University Graduate School of Medicine, 3-39-22 Showa, Maebashi, 371-8511 Japan
P-27 3.04 TRACE ELEMENT LEVELS AND REDOX MARKERS IN HUMAN ATHEROSCLEROSIS: RELATIONSHIP WITH APO E POLYMORPHISM. Paula A. Lopes [1], Patrícia Napoleão [1], Teresa Pinheiro [2], Maria C. Santos [3], Maria O. Rodrigues [4], Luciana Costa [4]; Fátima Ceia [1], Luis Vicente [1], Maria L. Pavão [5], Jean Neve [6], Ana M. Viegas-Crespo* [1]. C.B.A, Fac. Ciências, Univ. Lisboa, 1749-016 Lisboa, PORTUGAL [1]; I.T.N, Portugal [2]; C.Q.B., Fac. Ciências, Univ. Lisboa, PORTUGAL [3]; INSA, Lisboa, PORTUGAL [4]; C.I.R.N, Univ. Açores, P. Delgada, PORTUGAL [5]; Inst. Pharm., U. L. B., C. Plaine 205-5, Bruxelles, BELGIUM [6]
P-28 LB.25 QTc INTERVAL IN TYPE 2 DIABETIC PATIENTS IS SHORTENED BY CHROMIUM SUPPLEMENTATION. Matjaz Vrtovec*[1], Bojan Vrtovec [2], Alenka Briški [3], Andreja Kocijančič [1]. Dept of Endocrinology [1]; Dept of Cardiology [2]; Dept of Clinical Chemistry and Biochemistry [3]; University Medical Centre, Ljubljana, SI-1000, SLOVENIA
Category 9: Trace Elements and Neurological Diseases and Neuropsychological Impairment
P-29 9.01 EFFECT OF THERAPEUTIC IRON SUPPLEMENTATION ON DEVELOPMENTAL INDICIES IN CHILDREN 1-3 YEARS OF AGE WITH SEVERE ANEMIA. Sunil Sazawal*[1,2], Deepak Marwah [1], Priti Verma [1], Usha Dhingra [2], Saikat Deb [1], Rakesh Juyal [1], Meena Osmany [1], Archana Sarkar [1], Pratibha Dhingra [1], Jitender Kumar [1], Venugopal P Menon [1], Maureen Black [3], Robert E Black [2]. Center for Micronutrient Research, Annamalai University, India [1], Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore USA [2], Department of Pediatrics, University of Maryland, School of Medicine, Baltimore USA [3]
P-30 9.02 THE NEW EVIDENCE ON THE ROLE OF ELEMENTAL HOMEOSTASIS IN NEURO-DEGENERATIVE AND NEURO-PSYCHIATRIC DISORDERS. P. Shanmugavelu [1], S. S. Rao [2], M. L. Hegde [3], M. S. Mustak [3], R. B. Menon [1], N.M. Shamasundar [2] and K. S. J. Rao [3]. B.A.R.C, Mumbai , INDIA [1]; J.S.S. Medical College, Mysore, INDIA [2]; Department of Biochemistry and Nutrition, C.F.T.R.I, Mysore, INDIA [3]
P-31 9.04 ANEMIA IN CHILDREN 1-3 YEARS OF AGE IS ASSOCIATED WITH POORER SCORES ON ALL DEVELOPMENTAL INDICIES. Priti Verma* [1], Sunil Sazawal[1,2], Usha Dhingra [2], Rakesh Juyal [1], Deepak Marwah [1], Archana Sarkar [1], Pratibha Dhingra [1], Venugopal P Menon [1], Maureen Black [3], Robert E Black [2]. Center for Micronutrient Research, Annamalai University, India [1], Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore USA [2], Department of Pediatrics, University of Maryland, School of Medicine, Baltimore USA [3]
P-32 LB.17 ASSOCIATIONS BETWEEN IRON AND ZINC STATUS AND COGNITIVE PERFORMANCE IN SCHOOL-AGED CHILDREN IN INDONESIA AND AUSTRALIA. Saskia JM Osendarp, Katrine Baghurst, Widjaja Lukito, Jan Willem van Klinken on behalf of the Nutrition Enhanced Mental Opimalization (NEMO) Study Team
P-33 LB.07 EFFECTS OF LOW LEVEL LEAD EXPOSURE ON NEURO-BEHAVIORAL FUNCTION OF RATS, AND THE COUNTER EFFECTS AND MECHANISMS OF CALCIUM, ZINC SUPPLEMENT. Qiong Huang*，Xing-fen Yang， Jun-ming Huang, et al. Institute of Toxicology, Center for Disease Control and Prevention; Guangdong province, Guangzhou 510300, CHINA
P-34 LB.27 METALS IMBALANCE IN PARKINSON’S DISEASE: LEVELS IN THE CEREBROSPINAL FLUID. Alessandro Alimonti* [1], Beatrice Bocca [1], Giovanni Forte [1], Francesco Petrucci [1], Oreste Senofonte [1], Anna Pino [1], Livia Brusa [2], Giuseppe Sancesario [2]. Dept. Environment and Primary Prevention, Istituto Superiore di Sanità, Rome, Italy [1]; Dept. Neuroscience, University Tor Vergata, Rome, Italy [2]
14:30-17:30 Three Concurrent Sessions (Symposia C and D; Minisymposium 2)
Symposium C--Ballroom I
Managing Trace Element Bioavailability
Co-Chairs: Ross Welch and Gerald Combs, Jr.
Purpose of Session: Low bioavailability of certain essential mineral elements, e.g., calcium, iron, selenium, and zinc, from plant sources increases risk of morbidity from deficiency related diseases. For example, iron deficiency, which affects more than half of the world’s population, is to a large extent caused by low bioavailability from plant-based foods rich in phytate and polyphenols. Similarly, zinc deficiency, that recent data suggest is a co-deficiency with diet-related iron deficiency, is caused by binding by phytate and other indigestible ligands in plant-based foods. Morbidities from combined iron and zinc deficiency include growth stunting (from zinc deficiency), low immunity (from both deficiencies), low cognitive and neuromotor function (from both deficiencies), poor wound healing (from zinc deficiency), and anemia (from iron deficiency). The best common dietary source of iron and zinc is red meat. However, most of the world’s population has highly limited dietary access to red meat and is thus dependent on plants for iron and zinc. Therefore, one major challenge is to improve bioavailability of iron and zinc from plant based foods. Genetic engineering of plants to reduce binding of iron and zinc by ligands that cannot be digested by humans is a potential solution to wide spread iron and zinc deficiencies. This symposium will address the issue of practical and sustainable solutions for prevention of trace element deficiencies.
14:30 "Bioavailability: an Overview of Factors Affecting the Utilization of Trace Elements," Ross Welch
15:00 "Considering Chemical Speciation in Assessing Trace Element Bioavailability: the case of Selenium," Gerald Combs Jr.
15:30 "Breeding Plants with Bioavailable Trace Elements," Robin Graham
16:00 Delegate Tea Break
Special Presentations
16:30 "Genetic defects of copper transport: Wilson and Menkes Diseases," Bibudhendra Sarkar
17:00 "Advances in Nutritional Metrology," Venkatesh Iyengar
Symposium D--Ballroom II
Presidents' Session
Chair: Mohamed Abdulla
Purpose of Session: A series of new advances have been made in trace element nutrition and metabolism as they relate to common disease processes. Fibrosis, induced by a variety of conditions including wound healing and reaction to injury, interferes with several essential functions. New evidence suggests that lowering the amount of available copper limits destruction of lung alveoli and the subsequent decrease in oxygen uptake, an end result of fibrosis. The re-emergence of rickets and the continued insurgence of osteoporosis are associated in part with changes in nutritional factors. Significant progress has been made in understanding how bone synthesis, calcification, maintenance, and remodeling are affected by several dietary trace elements including zinc, copper, magnesium, boron, and silicon. Therapeutic trials of mixtures of trace elements indicate apparent efficacious effects of these element in postmenopausal women with osteoporosis. Brain development and function are dependent upon adequate zinc and iron nutrition. This is of concern for the segment of the population of premenopausal women who do not eat red meat on a regular basis and commonly experience iron deficiency. They are also likely to be zinc deficient. Randomized, controlled therapeutic trials of zinc or iron with other potentially limiting micronutrients indicate the efficacious nature of these trace elements in maintaining neuropsychological function. Zinc is also essential for cell mediated immune function such that zinc deficiency decreases the numbers of T-helper cells, production of interleukin 2, and other immunity facilitating cytokines that decrease morbidity from infections. Four past presidents of the ISTERH will summarize the new advances in trace element nutrition and metabolism pertaining to neuropsychological, immune, bone, and pulmonary function.
14:30 "Developmental Zinc Deficiency Causes Disease in Later Life," Harold Sandstead
15:00 "Essentiality of copper, zinc, magnesium, boron and silicon in bone development and function," Forrest Nielsen
15:30 "Anti-oxidant effect of zinc in humans," Ananda Prasad
16:00 Delegate Tea Break
16:30 "Lowering copper availability reduces signaling from key cytokines: use for antiangiogenesis, antifibrosis and antiinflammation," George Brewer
Minisymposium 2--Rattanakosin
Minisymposium : Trace Elements and Neurological Diseases/Toxicology of Trace Elements
Category 9: Trace Elements and Neurological Diseases and Neuropsychological Impairment
Co-Chairs: Hiroshi Satoh and Hiroko Kodama
14:30 9.03 ZENITH PROJECT: THE EFFECTS OF ZINC ON BEHAVIOURAL AND PSYCHOLOGICAL PARAMETRES IN HEALTHY OLDER ADULTS: PRELIMINARY FINDINGS. Liz Simpson* [1], Chris McConville [1], Gordon Rae [1], Barbara Stewart [1], Elizabeth Maylor [2], Jenni Birrell [3], Victoria Jewell [1], Jacqueline O’Connor [1], Angela Polito [4], Nathalie Meunier [5], Maud Andriollo [6], Charles Coudray [5]. School of Psychology, Niche University of Ulster, Cromore Road, Coleraine, County Londonderry, NORTHERN IRELAND, BT52 1SA [1]; Department of Psychology, University of Warwick, Coventry, ENGLAND CV4 7AL [2]; Cambridge Cognition Limited Tunbridge Court Tunbridge Lane Bottisham Cambridge, ENGLAND CB5 9DU [3]; National Institute for Food and Nutrition Research Human Nutrition Unit, via Ardeatina 546, 00178 Roma, ITALY [4]; Centre de Recherche en Nutrition Humaine d’Auvergne, Unité Maladies Métaboliques et Micro-Nutriments, Inra, Rentre de Recherche de Clermont-Ferrand/Theix, 63122 Saint Genès Champanelle, FRANCE [5]; Laboraroire de Biologie de Stress Fxydant, Faculté de Pharmacie, Domaine de la Merci, 38700 la Tronhe, FRANCE [6]
14:45 9.05 SELENIUM SUPPLEMENTATION IN JUVENILE NEURONAL LIPOFUSCINOSIS PATIENTS. 30 YEARS EXPERIENCE . Tuomas Westermarck*, Faik Atroshi Rinnekoti Research Center, 02980 Espoo; Dept. Pharmacology & Toxicology, University of Helsinki, FINLAND
15:00 9.07 PLASMA ZINC AND COPPER LEVELS IN AUTISTIC CHILDREN. Özgür Yorbik* [1], Cemal Akay [2], Ahmet Sayal [2], Adnan Cansever [3], Teoman Söhmen [4], Ayhan O. Çavdar [5]. Child and Adolescent Psychiatry Department, GATA (Gülhane Military Medical Academy) [1]; GATA-Toxicology Department [2]; GATA Psychiatry Department [3]; Chief, GATA Child and Adolescent Psychiatry Department, Etlik, Ankara [4], Chief Trace Element Research Group of TÜBA (Turkish Academy of Sciences) Ankara, TURKEY [5]
Category 11: Toxicity of Trace Elements
15:15 11.01 FIELD-FLOW FRACTIONATION-INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY: A NEW APPROACH TO STUDY METAL-PROTEIN INTERACTION. Atitaya Siripinyanond [1,2], and Ramon M. Barnes*[1]. University Research Institute for Analytical Chemistry, 85 N. Whitney Street, Amherst, MA 01002-1869, USA [1]; Department of Chemistry, Mahidol University, Rama VI Rd., Bangkok 10400, THAILAND [2]
15:30 11.02 EXTREME HIGH BLOOD SELENIUM CONCENTRATIONS IN POLAR ESKIMOS. Bente Deutch*, Henning Sloth Pedersen, and Jens C Hansen. Centre for Arctic Environmental Medicine, University of Aarhus, Vennelyst Boulevard 6, Aarhus DK-8000, DENMARK
15:45 11.03 GENETIC VARIATION IN ATP7B PROMOTOR AND 5’ UTR IN HAN CHINESE PATIENTS WITH WILSON’S DISEASE. Yan-Hong Gu* [1], Si-Lian Du [2], Hiroko Kodama [1], Qing-Jiu Gu [3], Han-Jun Sun [4]. Dept. Pediatrics, Teikyo University School of Medicine, Tokyo, 173-8605 JAPAN [1]; Dept. Pediatrics, The Affiliated Hospital of Qingdao Medical College, Qingdao, 266000 CHINA [2]; Dept Surgery, TieJian Hospital of China Railway Construction Corporation, Beijing, 100855 CHINA [3]; Dept Otolaryngology, Chinese Armed Police General Hospital, Beijing, 100039 CHINA [4]
16:00 Delegate Tea Break
16:30 11.06 XENOBIOTIC-METABOLIZING ENZYMES IN IODINE and/or SELENIUM DEFICIENT RATS – THE EFFECTS OF FENVALERATE EXPOSURE. Pinar Erkekoglu, Aydan Caglayan, Belma Giray, Filiz Hincal*. University of Hacettepe, Faculty of Pharmacy, Department of Toxicology, Ankara, 06100, TURKEY
16:45 11.11 EFFECT OF COMBINATION THERAPY WITH COPPER AND A CHELATOR IN THE MACULAR MOUSE, AN ANIMAL MODEL OF MENKES DISEASE. Hiroko Kodama*, Emi Sato, Yan-Hong Gu, Katsuaki Shiga. Dept. Pediatrics, Teikyo University School of Medicine, Tokyo, 173-8605 JAPAN
17:00 11.13 NEPHROPATHY INDUCED BY CHRONIC EXPOSURE TO DIETARY CADMIUM IN DIABETIC AND NON-DIABETIC SUBJECTS . Melissa Haswell [1], Soisungwan Satarug [2], Victor McGrath [1], Maria Walmby [1], Jack Ng [2] and Michael R Moore*[2,3]. Centre for Indigenous Health, The University of Queensland [1], National Research Centre for Environmental Toxicology [2], Queensland Health Scientific Services, AUSTRALIA [3]
17:15 11.14 POPULATION EXPOSURES TO CADMIUM AND IMPACTS ON RENAL FUNCTION. Michael R Moore*, Soisungwan Satarug. National Research Centre for Environmental Toxicology, and Queensland Health Scientific Services, Brisbane, AUSTRALIA
17:45 11.18 RENAL TUBULAR DYSFUNCTION AND MORTALITY IN RESIDENTS OF A CADMIUM POLLUTED AREA IN JAPAN, A 20-YEAR FOLLOW-UP STUDY. Muneko Nishijo* [1], Hideaki Nakagawa [1], Yuko Morikawa [1], Katsuyuki Miura [1], Kenji Tawara [1], Teruhiko Kido [2], Etsuko Kobayashi [3] , Koji Nogawa [3]. Dpt. Public Health, Kanazawa Medical University, Uchinada, JAPAN [1]; Dpt. Community Health Nursing, Kanazawa University, Kanazawa, JAPAN [2]; Dpt. Occupational and Environmental Medicine, Chiba University, Chiba, JAPAN [3]
18:00 11.21 RENAL METAL LOAD AND CYP4F2: IMPLICATION IN RENAL EICOSANOID SYNTHESIS AND HIGH BLOOD PRESSURE DEVELOPMENT. Soisungwan Satarug* [1], Jason R Baker [2], Aedah Abu-Bakar [1] Rob J. Edwards [3] Jerome M. Lasker [4] and Michael R. Moore[1,5]. National Research Centre for Environmental Toxicology, University of Queensland [1]; Flinders University, AUSTRALIA [2]; Imperial College, UK [3], Hackensack University, USA [4], Queensland Health Scientific Services [5]
___________________________________________________
NOTE: This is Conference Program Part 1 (November 7-10, Sunday through Wednesday). Please click HERE, or below (on any session) to see the Conference Program Part 2, November 11-12, Thursday-Friday:
Plenary Session #4: Cardiovascular Diseases and Trace Elements, click HERE,
Symposium E: Metabolic Syndrome & Trace Elements, click HERE,
Symposium F: Toxic Metals Causing Human Diseases in Asia, click HERE,
Poster Session #3, click HERE,
ISTERH will not assume responsibility for medical expenses of conference participants and their guests at the conference. All participants are urged to ensure that they and their guests are covered by their own travel and health insurance policies while traveling to/from and while attending the conference.
ISTERH is not responsible for private possessions lost or stolen at the conference.
