SUNDAY AFTERNOON, October 21, 2007
14:30 FOYER
Registration desk opens
17:30-17:45 Main entrance to Creta Maris Hotel
Board free shuttle to Opening Reception(taxis available at delegate expense after this period)
17:45-21:00 “LYCHNOSTATIS”, the Cretan open-air Museum
17:45 Delegates stroll through the winding alleys of a garden lined with native fruit-trees; smell the aromatic herbs of Crete; visit two typical Cretan houses of the late 19th century, a white-washed chapel, restored windmill, shepherd's-shelter, threshing - floor, olive-oil factory, bee’s and wax-house, workshops of weaving, plant-dyeing wool and ceramics.
18:30 Grape-treading in the Museum wine vats; audio-visual slide-show about Crete
19:15 Traditional Cretan food
20:30 Main entrance of LYCHNOSTATIS
Board shuttle back to Creta Maris Hotel
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MONDAY MORNING, October 22
7:30 Foyer
Registration desk opens
7:30 OLYMPUS
Speaker Ready Room
8:00 OLYMPUS
Monday posters open. Presentation time: 13:30-14:30
8:00 OLYMPUS
Commercial Exhibits
9:00-9:30 MINOS
9:00 Welcome and Opening Ceremony
Mr. Serafim Tsokas, Governor of the Region of Crete
Ms. Evangelia Shinaraki-Iliaki, Prefect of Heraklion
Mr. Spiros Danellis, Mayor of Hersonissos
Mr. Nikos Skoulas, President of Trinity College, Crete, Greece; Past Minister of Hellenic Tourism
Dr. Curtiss D. Hunt , President, International Society for Trace Element Research in Humans (ISTERH)
Prof. Sophie Ermidou-Pollet, President, Hellenic Trace Element Society (HTES)
Dr. Ole Andersen, Representative, Nordic Trace Element Society (NTES)
Dr. Dorothy Klimis-Zacas, Chair, Conference Local Organizing Committee
Members of the ISTERH/NTES/HTES '07 Organizing Committee on Platform
Curtiss Hunt, Chair, Organizing Committee; President, ISTERH
Sophie Ermidou-Pollet, President, HTES
Ole Andersen, Representative, NTES
Dorothy Klimis-Zacas, Chair, Local Organizing Committee; Member, ISTERH
Monica Nordberg, Chair, Abstract Committee; Vice-President, ISTERH
Jeanne Freeland-Graves, Chair, Fundraising Committee; Council Member, ISTERH
Hiroko Kodama, Chair, Publicity Committee; Secretary, ISTERH
Serge Pollet, Member at Large; Vice-President, HTES
George Brewer, Member at Large; Council Member, ISTERH
Harold Sandstead, Member at Large; Immediate Past-President, ISTERH
9:40-10:40 MINOS
Plenary Session #1 (Part 1): Keynote Address
Chair: Dorothy Klimis-Zacas
Co-Chair: Mary Yannakoulia
9:40 "Mediterranean Diet, Traditional Foods and Health”, Antonia Trichopoulou
10:40 Delegate Coffee Break (OLYMPUS)
11:10-12:30 MINOS
Plenary Session #1 (Part 2): "Trace Minerals: Modulators of Arterial Function"
(ISTERH/NTES/HTES '07 acknowledges the generous support from the ARISTIDES DASKALOPOULOS FOUNDATION , HAROKOPIO UNIVERSITY, and the WILD BLUEBERRY ASSOCIATION OF NORTH AMERICA )
Chair: Dorothy Klimis-Zacas
Co-Chair: Mary Yannakoulia
Purpose of Session: Recent advances in molecular biology and biochemistry have uncovered the crucial role trace minerals play on the vascular endothelium and cardiovascular disease. Current research on the role(s) manganese, selenium and copper have in cell-signaling, expression of cytoprotective genes and vascular and microvascular regulation will be discussed in this session. Manganese has been documented to be involved in arterial glycosaminoglycan metabolism and structure resulting in atheroprotection. Additionally, manganese is critical in maintenance of vasomotor tone by affecting the nitric oxide and cyclo-oxygenase pathways. Selenium as a component of potent antioxidant enzymes, the selenoproteins, directly neutralizes proatherogenic reactive oxygen species. The regulatory role of individual selenoproteins in orchestrating the expression of genes necessary for endothelial cell survival during oxidant stress through their ability to control redox sensitive signaling events will be discussed. Dietary copper and cuproenzymes play a significant role in microvascular control mechanisms such as endothelium-dependent regulation of arteriolar vascular smooth muscle. Dietary copper deficiency, with its resultant inactivation of cuproenzymes, affects nitric oxide-mediated dilation, increases superoxide anion (O2) production and decreases NO availability.
11:10 "Manganese: modulator of vascular function, structure and metabolism”, Dorothy Klimis-Zacas and A. Kalea
11:40 "The role of copper in nitric oxide mediated vasodilation”, Dale Schuschke
12:10 "Selenium status and regulation of vascular homeostasis”, L. Sordillo
12:30 CRETA MARIS MAIN RESTAURANT
Delegate Lunch (covered in registration fee)
MONDAY AFTERNOON, October 22
13:30-14:30 OLYMPUS
POSTER SESSION 1
Category 1: Trace Element Intakes, Dietary Patterns, Bioavailability, and Tissue Distributions
Chair: Sophie Ermidou-Pollet and Serge Pollet
Co-Chair: Ivana Djujic
Co-Chair: Manfred Anke
Co-Chair: Tadeusz Kosla
P-1 1.P01 THE EFFECT OF ENRICHMENT WITH SUNFLOWER SEED, SESAME SEED AND ALPHA TOCOPHEROL ACETATE TO LINOLEIC ACID QUANTITY IN COOKIES.
Sumalika Piammongkol and Patcharin Pakdeechanuan. Prince of Songkla University (Pattani, Thailand)
P-2 1.P02 ESTIMATION OF THE POTENTIALLY BIOAVAILABLE FRACTION OF COPPER AND ARSENIC IN SOILS BY DGT.
Ilenia Cattani, Raffaella Boccelli, Ettore Capri, and Attilio A.M. Del Re.
Università Cattolica del Sacro Cuore (Cremona, Italy)
P-3 1.P03 RESEARCH STUDIES RELATED TO THE IMPACT OF ENVIRONMENTAL EXPOSURE TO BORON ON PEOPLE LIVING IN TURKIYE.
Sinem Karakas, and Erk Inger.
National Boron Research Institute (Ankara, Turkey)
P-4 1.P04 MOLYBDENUM IN THE ENVIRONMENT IN CONNECTION WITH BIOLOGICAL EFFECTS.
Vadim Ermakov, and Angelina Soboleeva.
V.I. Vernadsky Institute of Geochemistry and Analytical Chemistry (Moscow, Russian Federation)
P-5 1.P05 ASSESSMENTS OF EXPOSURE TO DIETARY TRACE ELEMENTS IN CHINA.
Junquan Gao1, Xiaowei Li1, Xiaoxi Liu1, and Liping Liu2.
1National Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention (Beijing, China); 2Beijing CDC (Beijing, China)
P-6 1.P06 Open.
P-7 1.P07 BENEFICIAL ROLE OF MONOTHIOLS ALONG WITH MAGNESIUM IN THE MOBILIZATION OF MERCURY: A POSSIBLE MECHANISM.
Varsha Singh1, Mohamed Abdulla 2, Sadhana Shrivastava1, and Sangeeta Shukla1.
1Jiwaji University (Gwalior, India); 2Trace Element- Institute for UNESCO, (LYON, France)
P-8 1.P08 TRACE ELEMENTS IN THE DIGESTIVE SYSTEM OF THE RAT.
Heloisa Bordallo, Torsten Bartz, Dorothea Alber, and Antonios Kyriakopoulos.
Hahn-Meitner-Institut (Berlin, Germany)
P-9 1.P09 LYSOSOMES OF THE GASTRIC MUCOSA CELLS: A SITE OF ACCUMULATION OF ALUMINIUM AND INDIUM.
Tekaya Leila, Maghraoui Samira, Maaroufi Houcine, and Ayadi Ahlem.
Faculty of Medicine of Tunis (Ariana, Tunisia)
P-10 1.P10 STUDENT TRAVEL COMPETITION AWARDEE: MIXED EXPOSURE TO NEPHROTOXIC METALS IN A BANGLADESHI POPULATION WITH PREVALENT MALNOURISHMENT AND RISKS FOR KIDNEY EFFECTS.
Anna-Lena Lindberg1, Shams El Arifeen2, Mahfuzar Rahman2, Lars-Åke Persson3, Eva-Charlotte Ekström3, Marie Vahter4, Alfred Bernard5, and Marika Berglund4.
1Karolinska Institute (Stockholm, Sweden); 2International Centre for Diarrhoeal Disease Research (ICDDR,B) (Dhaka, Bangladesh); 3International Maternal and Child Health, Uppsala University (Uppsala, Sweden); 4Institute of Environmental Medicine, Karolinska Institute (Stockholm, Sweden); 5University of Louvain (Brussels, Belgium)
P-11 1.P11 CONTAMINATION OF SELECTED FOOD BY HEAVY METALS.
Jozef Golian, Peter Zajac, Robert Toman, and Branislav Siska.
Slovak Agricultural University (Nitra, Slovakia)
P-12 1.P12 INVESTIGATION OF INTERRELATIONSHIPS BETWEEN HAIR AND WHOLE BLOOD MACRO AND TRACE ELEMENT CONTENTS IN HUMANS.
Anatoly Skalny 1, Andrei Grabeklis1, Sergey Nadorov2, and Margarita Skalnaya3.
1Institute of General Pathology and Pathophysiology RAMS (Moscow, Russian Federation); 2Institute of Pharmacology RAMS (Moscow, Russian Federation); 3ANO "Centre or Biotic Medicine" (Moscow, Russian Federation)
P-13 1.P13 A NATION-WIDE SURVEY OF TRACE ELEMENTS IN LYNX, WOLVERINES, WOLVES AND BROWN BEARS IN NORWAY.
Trond Peder Flaten1, Lars Haug Andersen2, Aase Marie Hersleth Holsen3, Vivian Grønhaug Ottemo3, Hans Christian Pedersen4, Eiliv Steinnes3, Syverin Lierhagen3, and Bjørn Munro Jenssen2.
1Norwegian University of Science and Technology (Trondheim, Norway); 2Norwegian University of Science and Technology, Department of Biology (Trondheim, Norway); 3Norwegian University of Science and Technology, Department of Chemistry (Trondheim, Norway); 4Norwegian Institute for Nature Research (Trondheim, Norway)
P-14 1.P14 IRON-ZINC-COPPER INTERACTIONS IN EDIBLE INSECT JUMIL BUG EUCHISTUS TAXCOENSIS A.
Virginia Melo1, Ma. Del Carmen Herrera2, Jorge Rivero3, Edilerto Castrejon4, and Jose Salas4.
1Universidad Autonoma Metropolitana-X (Mexico, Mexico); 2Uam-I (Mexico, Mexico); 3Unam-Cch-Oriente (Mexico, Mexico); 4Uam-X (Mexico, Mexico)
P-15 1.P15 MERCURY IN URINE AFTER DENTAL RESTORATION.
Syverin Lierhagen1, and Tore Syversen2.
1Norwegian University of Science and Technology (Trondheim, Norway); 2NTNU (Trondheim, Norway)
P-16 1.P16 TRACE ELEMENTS IN BLOOD FROM DENTAL HEALTH PERSONNEL.
Tore Syversen1, Lars Evje2, Torgunn Qvenild3, Kristin Svendsen2, and Bjørn Hilt3.
1Norwegian University of Science and Technology (Trondheim, Norway); 2NTNU (Trondheim, Norway); 3St.Olavs University Hospital (Trondheim, Norway)
P-17 1.P17 INFLUENCE OF ORGANIC SELENIUM ADDITION IN FEED RATION ON MUSCLE TISSUE STRUCTURE AND MEAT QUALITY IN CALVES.
Svatoslav Hluchy, Robert Toman, and Juraj Cubon.
Slovak Agricultural University (Nitra, Slovakia)
P-18 1.P18 ENVIRONMENTAL RISKS OF POTENTIALLY TOXIC METALS MOBILISED FROM ACID SULPHATE SOILS IN FINLAND: A LITERATURE REVIEW.
Rasmus Fältmarsch1, Mats Åström2, and Kari-Matti Vuori3.
1Åbo Akademi University (Åbo, Finland); 2Department of Biology and Environmental Science, Kalmar University (Kalmar, Sweden); 3Finnish Environment Institute and University of Oulu, Department of Biology (Oulu, Finland)
P-19 1.P19 LEVELS OF SELECTED TRACE ELEMENTS IN BLOOD OF CZECH SCHOOL CHILDREN AND WOMEN.
Milena Cerna1, Andrea Batariova1, Vera Spevackova1, Maja Cejchanova1, Katerina Wranova2, Bohuslav Benes1, and Jiri Smid1.
1National Institute of Public Health (Prague 10, Czech Republic); 2National Institute of Public Health, Charles University Faculty of Science in Prague (Prague 10, Czech Republic)
P-20 1.P20 TRACE ELEMENTS IN NUTRITIONAL SUPPLEMENTS.
Lars Evje, Marte Aurstad Aspnes, and Tore Syversen. Department of Neuroscience, Norwegian University of Science and Technology (Trondheim, Norway)
P-21 1.P21 MINERALS AND PHYTATES CONTENT OF SOME COMPLEMENTARY FOODS FROM CAMEROON.
Marie Modestine Kana Sop1, Mathias Seifert2, Manfred Anke3, Donald Oberleas4; 1University of Douala (Douala, Cameroon); 2Research Institution (Detmold, USA); 3University of
Jena, Emeritus (Jena, Germany); 4Texas Tech University (Emeritus) (Texas, USA)
P-22 1.P22 ASSESSMENT OF MINERALS CONTENT AND ACID EXTRACTION IN MAIZE BASED COMPLEMENTARY FOODS FROM CAMEROON USING HR-ICP-MS.
Marie Modestine Kana Sop1, Marte Aspnes Aurstad2, Renate Meloe2, Lars Evje2, and Tore Syversen2.
1University of Douala (Douala, Cameroon); 2Norwegian University of Science and Technology (Trondheim, Norway)
P-23 1.P23 EFFECT OF TRACE ELEMENTS IN A COMPLEX PREPARATE (IMMUNOVET-HBMTM) ON THE ABSORPTION FROM THE ANIMAL DIGESTIVE TRACT.
Jakab Laszlo, Nagy Gyula, and Kosa Emma. Szent Istvan University, Faculty of Veterinary Science
P-24 1.P24 EFFECT OF ONE YEAR OF IRON/ZINC FORTIFICATION ON BODY IRON STORES OF CHILDREN AGED 1-4 YEARS.
Pratibha Dhingra1, Usha Dhingra2, Archana Sarkar1, Venugopal P Menon1, Robert E Black2, Saikat Deb2, and Sunil Sazawal2.
1Center for Micronutrient Research,Annamalai University (New Delhi, India); 2Johns Hopkins University (Baltimore, USA)
P-25 1.P25 ELEVATED LEVELS OF SELENIUM IN THE TYPICAL DIET OF THE AMAZONIAN RIPARIAN POPULATION.
Mélanie Lemire1, Fábio Sidonio de Barros Evangelista2, Elene Paltrineiri Nardi2, Myriam Fillion1, Jean Rémy Davée Guimarães3, Fernando Barbosa Jr.2, and Donna Mergler1.
1Centre de recherche interdisciplinaire sur la biologie, la santé, la société et l’environnement (CINBIOSE), Université du Québec à Montréal (Montréal, Canada); 2Depto. de Análises Clínicas, Toxicológicas e Bromatológicas, Universidade de São Paulo (Ribeirão Preto, Brazil); 3Instituto de Biofísica, Universidade Federal do Rio de Janeiro (Rio de Janeiro, Brazil)
P-26 1.P26 STUDY OF BIOAVAILABILITY AND TOXICITY OF ARSENIC AND MERCURY IN CHINESE PROPRIETY MEDICINES (CPM) USING AN ANIMAL MODEL.
Ujang Tinggi1, Ross Sadler1, Barry Noller2, Alan Seawright2, Jack Ng2, Michael Moore2, Kelli Cooper3, Garry Golding1, Henry Olszowy1, and Pieter Scheelings1.
1Queensland Health Scientific Services (Brisbane, Australia); 2University of Queensland (Brisbane, Australia); 3Royal Melbourne Institute of Technology (Melbourne, Australia)
P-27 1.P27 IRON BIOAVAILABILITY FROM GRASSHOPPERS: EDIBLE INSECTS VS SPINACH LEAVES.
Virginia Melo1, MA. Del Carmen Herrera2, and Jorge Rivero3.
1UAM-X (MEXICO, Mexico); 2UAM-I (MEXICO, Mexico); 3UNAM-CCH-ORIENTE (MEXICO, Mexico)
P-28 1.P28 THE ELEMENT COMPOSITION OF COW'S MILK OF MOSCOW REGION.
Svetlana P. Zamana, Victor N. Kutrovsky, and Taras G. Fedorowskiy.
Scientific Research Agricultural Institute of Central Regions of Non-chernozem Zone (Nemchinovka,Moscow region, Russian Federation)
P-29 1.P29 ARSENIC EXCRETION IN HEALTHY, NON-SMOKING ADULT NORWEGIANS: A RANDOMISED CONTROLLED SEAFOOD DIET TRIAL.
Marianne Molin1, Vibeke Telle-Hansen1, Lisbeth Dahl2, Stine Marie Ulven1, Marianne Holck1, Grete Skjegstad1, Oddlaug Ledsaak1, Jens Sloth2, Arne Oshaug1, Kåre Julshamn2, and Helle Margrete Meltzer3.
1Akershus University College (Lillestrom, Norway); 2National Institute of Nutrition and Seafood Research (NIFES) (Bergen, Norway); 3Norwegian Institute of Public health (Oslo, Norway)
P-30 1.P30 INFLUENCE OF PROBIOTICS PREPARATIONS ON AN EXCHANGE OF HEAVY METALS.
Sergei Miroshnikov, Olga Kvan, Anatolii Skalny, Svyatoslav Lebedev, and Shamil Rahmatullin.
Orenburg State University (Orenburg, Russian Federation)
P-31 1.P31 INFLUENCE OF THE FERMENTAL PREPARATION ON THE ELEMENT STATUS OF CARP IN CONDITIONS OF VARIOUS NUTRITION SECURITY.
Elena Miroshnikova, Anatolii Skalny, and Aleksandr Barabash.
Orenburg State University (Orenburg, Russian Federation)
P-32 1.P32 MINERAL STATUS OF ENERGY ENTERPRISE WORKERS: RESULTS OF CORRECTION.
Oksana Baranova, Svetlana Notova, Anatolii Skalny, and Larisa Chadova.
Orenburg State University (Orenburg, Russian Federation)
P-33 1.P33 TRACE ELEMENT STATUS OF A BRAZILIAN ALTERNATIVE FOOD
Elisabete De Nadai Fernandes1, Peter Bode2, Claudio Gonzaga3, Clara Brandao4, Marcio Bacchi3, and Siu Mui Tsai3.
1Nuclear Energy Center for Agriculture, University of Sao Paulo (Piracicaba, Brazil); 2Delft University of Technology (Delft, Netherlands); 3Nuclear Energy Center for Agriculture (Piracicaba, Brazil); 4 Ministry of Health (Brasilia, Brazil)
P-34 1.P34 ROLE OF SELENIUM PHYSIOLOGY IN PREVENTION AND TREATMENT OF MERCURY TOXICITY.
Nicholas Ralston, and Laura Raymond.
University of North Dakota (Grand Forks, USA)
P-35 1.P35 MANGANESE STATUS IN FREE RANGING EUROPEAN BISONS FROM BIALOWIEZA PRIMEVAL FOREST.
Tadeusz KOŚLA, Ewa Małgorzata SKIBNIEWSKA, Aleksandra MARCZAK, Michał SKIBNIEWSKI, and Grażyna URBAŃSKA-SŁOMKA. Warsaw University of Life Sciences-SGGW, (Warsaw, Poland)
Category 2: Cancer and Oxidative Stress
Chair: Emily Ho
Co-Chair: Bernard Hennig
P-36 2.P01 TREATMENT OF ACUTE LYMPHOCYTIC LEUKEMIA USING ZINC ADJUVANT WITH CHEMOTHERAPY AND RADIATION-A CASE HISTORY AND HYPOTHESIS.
George Eby.
George & Patsy Eby Foundation (Austin, TX, USA)
P-37 2.P02 EFFECT OF SELENIUM SUPPLEMENTATION ON THE SERUM LEVEL OF PROSTATE-SPECIFIC ANTIGEN (PSA) IN HIGH PSA SUBJECTS.
Hiroshi Koyama1, Tetsuya Otani2, Yoko Katsuya1, Rizky Abdulah1, Kenji Kobayashi1, Kazuto Ito2, Kazuhiro Suzuki2, and Masami Murakami3.
1Gunma University Graduate School of Medicine (Maebashi, Japan); 2Department of Public Health, Gunma University Graduate School of Medicine (Maebashi, Japan); 3Department of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine (Maebashi, Japan)
P-38 2.P03 SELECTED TRACE ELEMENTS AND CADMIUM CONCENTRATIONS IN MALIGNANT, HYPERTROPHIC, AND NORMAL PROSTATIC TISSUES.
Adam Darago1, Jan Taczalski2, Andrzej Sapota1, and Anna Kilanowicz1.
1Medical University of Lodz (Lodz, Poland); 2District Hospital (Zgierz, Poland)
P-39 2.P04 RISK ANALYSIS OF SELENIUM IN KOREAN HEALTH-FUNCTIONAL FOODS.
Jong-Min Woo.
Korea Food and Drug Administration (Seoul, Korea, Rép. of South korea)
P-40 2.P05 DESIGN, SYNTHESIS, AND INVESTIGATION OF COPPER (II) COMPLEX OF 3-AMINOFLAVONE (AF) WITH ANTICANCER ACTIVITY.
Justyn Ochocki1, Elzbieta Zyner1, Andrea Erxleben2, and Lukasz Glinka1.
1Medical University (Lodz, Poland); 2Chemistry Department (Galway, Ireland)
P-41 2.P06 EFFECT OF FLUOXETINE ON TOLERANCE TO ANALGESIC EFFECT OF MORPHINE IN MICE WITH SKIN CANCER.
Alireza Mohajjel Nayebi1, Hassan Rezazadeh1, Yousef Parsa1, and Mohamed Abdulla2
1Tabriz University of Medical Sciences (Tabriz, Iran, Islamic Rep. of); 2Trace Element Institute for UNESCO, International Center (Lyon, France)
P-42 2.P07 INHIBITORY EFFECT OF CHROZOPHORA TINCTORA EXTRACT (METHANOL) ON FERRIC NITRILOTRIACETATE INDUCED OXIDATIVE STRESS IN RAT KIDNEY TISSUE.
Hassan Rezazadeh1, Abbas Delazar1, Alireza Mohajjel Nayebi1, and Mohamed Abdulla2.
1Tabriz university of medical sciences (Tabriz, Iran, Islamic Rep. of); 2Trace Element Institute for UNESCO, International Center (Lyon, France)
P-43 2.P08 CLINICAL ELEMENTOLOGY IN ONCOLOGY: EXPERIENCES AND PROPOSALS FROM GERMANY.
Oliver Micke1, Jens Büntzel2, Frank Bruns3, Michael Glatzel4, Robert Hunger5, Klaus Kisters6, and Ralph Mücke7.
1Franziskus Hospital (Bielefeld, Germany); 2Department of Otolaryngology, Südharz Hospital (Nordhausen, Germany); 3Medical School of Hannover (Hannover, Germany); 4Department of Radiotherapy, Central Hospital (Suhl, Germany); 5German Working Group Trace Elements and Electrolytes - AKTE (Chur, Switzerland); 6Department of Internal Medicine, St. Anna Hospital (Herne, Germany); 7Department of Radiotherapy, St. Josefs Hospital (Wiesbaden, Germany)
P-44 2.P09 EFFECTS OF LONG-TERM ANTIOXIDANT (SELENIUM AND VITAMIN E) AND IBUPROFEN ANTIOXIDANT THERAPY ON OXIDATIVE STRESS AND LIPID PEROXIDATION.
Liga Larmane1, Tija Zvagule2, Andrejs Skesters1, Alise Silova1, Kim Rainsford3, Nina Rusakova1, and Jelena Reste2.
1Riga Stradin's University (Riga, Latvia); 2P. Stradins Clinical University Hospital (Riga, Latvia); 3Sheffield Hallam University (Sheffield, United Kingdom)
P-45 2.P10 TRACE ELEMENTS LEVELS AND CANCER INCIDENCE IN EUROPE.
Jilang Pan1, Jane Plant1, K. Vala Ragnarsdottir2, and Nick Voulvoulis1.
1Imperial College London (London, United Kingdom); 2University of Bristol (Bristol, United Kingdom)A
P-46 2.P11 TRACE ELEMENTS THAT PROTECT AGAINST THE FREE RADICAL: FACTOR ANALYSIS.
Nikola Ivicic, Nevenka Kopjar, Juraj Prejac, and Berislav Momcilovic.
Institute for Medical Research and Occupational Health (IMI) (Zagreb, Croatia)
P-47 2.P12 INVESTIGATION OF CYTOTOXIC EFFECTS OF THALLIUM ACETATE AND ELLAGIC ACID ON C6 CELL LINE.
Oge Basoglan, Filiz Susuz, and Zerrin Canturk. Anadolu University (Eskisehir, Turkey)
P-48 2.P13 ASSOCIATION OF DIETARY MAGNESIUM AND DNA REPAIR CAPACITY WITH LUNG CANCER RISK. Somdat Mahabir, Qingyi Wei, Margaret Spitz, and Michele Forman. University of Texas M. D. Anderson Cancer Center (Houston, Texas, USA)
P-49 2.P14 TRACE ELEMENTAL CONSTITUTION OF PATIENTS WITH ORAL SUB-MUCOUS FIBROSIS AND LEUKOPLAKIA AND ITS POSSIBLE CORRELATION WITH ENDOGENOUS ANTIOXIDANT STATUS.
Anindita Chakraborty1, Sudarshan Mathummal1, Ranjan Ghosh2, Prem Gandhi2, and JoyGopal Roy2.
1UGC-DAE Consortium for Scientific Research, Kolkata Centre (Kolkata, India); 2R Ahmed Dental College (Kolkata, India)
P-50 2.P15 CHARACTERIZATION OF TRACE ELEMENTS AND METALLOENZYMES AND ITS ASSOCIATION WITH THE IMMUNE STATUS IN ORAL CANCER PATIENTS.
Nabakanta Jana1, Anindita Chakraborty2, Surajit Bose3, JoyGopal Roy3, and Sudarshan Mathummal1,2.
1CharuChandra College, (Kolkata, India); 2UGC-DAE Consortium for Scientific Research, Kolkata Centre (Kolkata, India); 3R Ahmed Dental College (Kolkata, India)
P-51 2.P16 INVESTIGATION OF CYTOTOXIC EFFECTS OF THE BORON COMPOUNDS ON LEUKEMIA CELL LINE.
Zerrin Canturk1, Zafer Gulbas2, and Yagmur Tunalý1.
1Anadolu University (Eskisehir, Turkey); 2Osmangazi University (Eskisehir, Turkey)
P-52 2.P17 SELENIUM SUPPLEMENTATION IN HEAD AND NECK SURGERY.
Jens Buentzel1,2, Michael Glatzel1,2, Frank Bruns2, Klaus Kisters2, Oliver Micke2,3, and Ralph Muecke2.
1Suedharzkrankenhaus (Nordhausen, Germany); 2AKTE (German Working Group "Trace Elements iand Electrolytes n Oncology" (Bielefeld, Germany); 3Franziskus Hospital (Bielefeld, Germany) (Bielefeld, Germany)
P-53 2.P18 BORIC ACID AND PHENYL BORIC ACID CYTOTOXICITY IN BREAST CANCER CELL LINES.
Susan Meacham, Anu Elegbede, and Stephen Carper
University of Nevada Las Vegas (Las Vegas, USA)
P-54 2.P19 MECHANISM OF APOPTOSIS INDUCED BY COPPER IN PC12 CELLS.
Masaaki Kurasaki1, Masaki Kawakami1, Toshiyuki Hosokawa2, and Takeshi Saito3.
1Hokkaido University, Faculty of Environmental Earth Science (Sapporo, Japan); 2Hokkaido University, Higher Education (Sapporo, Japan); 3Hokkaido University School of Medicine (Sapporo, Japan)
14:30-17:30 Five Concurrent Sessions (Symposia A and B; Minisymposium #1, #2, and #3)
Symposium A--MINOS
Copper in Neurologic and Neurodegenerative Diseases
(ISTERH/NTES/HTES '07 acknowledges the generous support from PIPEX PHARMACEUTICALS, INC )
Chair: George Brewer
Purpose of session: The symposium will feature exciting new work implicating copper in Alzheimer’s disease. This includes animal model work in which copper exacerbates Alzheimers – like pathology and symptoms, evidence in humans that higher copper levels in the diet accelerate cognitive decline, and evidence that Alzheimer’s disease patients have elevated levels of “free” copper. The role of copper in other neurodegenerative diseases will also be discussed as well as therapeutic approaches to lowering copper levels.
14:30 "Overview of the role of copper in neurologic and neurodegenerative diseases and potential treatment with tetrathiomolybdate”, George Brewer
15:00 "Copper, cholesterol, and cognition: animal and human evidence”, D. Larry Sparks
15:30 "Excess of serum ‘free’ copper in patients with Alzheimer’s Disease”, Rosanna Squitti
16:00 Delegate Coffee Break (OLYMPUS)
16:30 "Dietary fat and copper effects on cognition”, Martha Clare Morris
17:00 "Investigations on the role of copper in human neurodegenerative disease using model systems”, James Camakaris
Symposium B--ATHENA-ARTEMIS
Health Effects of Low Dose Exposure to Toxic Metals
Symposium organized in collaboration with the Scientific Committee on the Toxicology of Metals, International Commission on Occupational Health
(ISTERH/NTES/HTES '07 acknowledges the generous support from FORMAS [The Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning], ATSDR [Agency for Toxic Substances and Disease Registry, U.S. Department of Health and Human Services] )and ICOH [International Commission on Occupational Health])
Chair: Gunnar Nordberg
Co-Chair: Bruce Fowler
Purpose of session: Recent data indicate that adverse effects on human health occurs at very low exposures to toxic metals. Effects have been shown even at background levels of exposure in groups of the general population. These effects are due to a combination of factors in addition to exposure to the toxic metal in question. Important factors are defective expression of chaperone proteins, combined exposure to other toxic substances and/or unfavorable life-style factors as well as genetic factors. This symposium aims at displaying recent findings in this field and to discuss these findings as a basis for future research. New research technologies should be employed(proteomics,metabolomics and genomics) for investigation of the health effects of the combined impact of the mentioned factors at low dose exposure to toxic metals.
14:30 "Introduction”, Gunnar Nordberg
14:40 "Proteomic and metabolomic biomarkers for assessing low dose toxic trace element interactions: an overview”, Bruce Fowler
15:10 "Neurological and renal effects of low dose exposure to elemental mercury from amalgam in children”, Lars Barregard
15:40 "Manganese exposure as a determinant of Parkinsonian damage”, Roberto Lucchini
16:10 Delegate Coffee Break
16:40 "Kidney and bone effects of low dose cadmium exposure in Sweden”, Agneta Akesson
17:10 "Factors influencing dose-response relationships of cadmium in humans - diabetes, metallothionein and metallothionein antibodies”, Taiyi Jin
Minisymposium 1--EUROPA-DANAE
Chair: Robert Yokel
Co-Chair: James Friel
Category 1: Trace Element Intakes, Dietary Patterns, Bioavailability, and Tissue Distribution
14:30 1.S01
ORAL ALUMINUM BIOAVAILABILITY FROM REPRESENTATIVE FOODS SHOWS FOOD PROVIDES MUCH MORE AL TO SYSTEMIC CIRCULATION, AND POTENTIAL AL BODY BURDEN, THAN DOES DRINKING WATER.
Robert Yokel1,2, and Rebecca Florence2.
1University of Kentucky College of Pharmacy (Lexington, USA); 2University of Kentucky College of Pharmacy (Lexington, USA)
14:45 1.S02
BORON IN THE ENVIRONMENT AND HUMAN POPULATION OF SAN JUAN, ARGENTINA.
Neil Ward1, and Andrea Marcilla2.
1University of Surrey (Guildford, United Kingdom); 2University of Surrey (Guildford, United Kingdom)
15:00 1.S03 STUDENT TRAVEL COMPETITION AWARDEE: FOOD-BASED STRATEGIES IMPROVE IRON STATUS IN 12-20 MONTH OLD NEW ZEALAND CHILDREN: A RANDOMISED CONTROLLED TRIAL.
Ewa Szymlek-Gay, Anne-Louise Heath, Elaine Ferguson, Andrew Gray, and Rosalind Gibson.
University of Otago (Dunedin, New Zealand)
15:15 1.S04
BIOAVAILABILITY OF SELENIUM IN BRAZIL NUTS.
Christine Thomson, and Alexandra Chisholm.
University of Otago (Dunedin, New Zealand)
15:30 1.S05
MOLYBDENUM CONTENT IN INFANT FORMULAS FROM NORTH AMERICA.
James Friel, Haifeng Yang, Rossel Sabourin, and Apollo Tsopmo.
University of Manitoba (Winnipeg, Canada)
15:45 1.S06
TRACE METAL ABUNDANCE SOIL AND GRASS IN ICELAND: LINKS WITH SHEEP SCRAPIE.
K. Vala Ragnarsdottir, and Darren J. Hawkins.
University of Bristol (Bristol, United Kingdom)
16:00 Delegate Coffee Break (OLYMPUS)
16:30 1.S07
BIOACCESSIBILITY OF ZINC IN WHOLE EGGS BY CONTINUOUS-FLOW DIALYSIS METHOD.
Hatairat Plaimast1,2, Prapaisri Sirichakwa1, Prapasri Puwastien1, Emorn Wasantwisut1, Kanchit Judprasong2, and Suwanna Kijparkorn2.
1Institute of Nutrition, Mahidol university (Nakhon Pathom, Thailand); 2Faculty of Veterinary Science, Chulalongkorn University (Thailand)
16:45 1.S08
ANALYTICAL DATA ON IRANIAN TYPICAL DIETS AND ITS BIOAVAILABILITY ASPECT BY TRACE ELEMENTAL STUDY IN DAILY DIETS.
Ahmad Gharib.
Amir Kabir University (Tehran, Islamic Rep. of Iran)
17:00 1.S09
INVESTIGATION OF CHROMIUM, COPPER, COBALT AND MOLYBDENUM IN SOME CEREALS CONSUMED IN KENYA.
Fredrick Oduor.
University of Nairobi (Nairobi, Kenya)
17:15 1.S10
THE DIETARY BORON INTAKE IN CHINA.
Xiaowei Li, and Junquan Gao.
National Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention (Beijing, China)
17:30 1.S11
WOMEN’S ZINC ABSORPTION IS UNAFFECTED BY DIETARY CALCIUM, WITH OR WITHOUT HIGH-PHYTATE FOODS.
Janet Hunt1, and Jeannemarie Beiseigel2. 1USDA/ARS/GFHNRC (Grand Forks, USA); 2General Mills (Minneapolis, USA)
Minisymposium 2--LEDA
Chair: Ayhan O. Çavdar
Co-Chair: Renty Franklin
Category 2: Cancer and Oxidative Stress
14:30 2.S01
CONCENTRATIONS OF SELECTED TRACE ELEMENTS, CADMIUM, AND STEROID HORMONES IN WOMEN WITH UTERINE MYOMAS .
Marzenna Nasiadek1, Ewa Swiatkowska2, Anna Nowinska2, and Andrzej Sapota1.
1Medical University of Lodz (Lodz, Poland); 2Polish Mother's Memorial Hospital-Research Institute (Lodz, Poland)
14:45 2.S02
BORIC ACID AND PHENYL BORIC ACID INDUCE APOPTOSIS IN PROSTATE CANCER CELL LINES.
Stephen Carper, Casey Hall, and Susan Meacham.
University of Nevada Las Vegas (Las Vegas, USA)
15:00 2.S03
ZINC REGULATES NFKAPPAB AND AP1 TRANSCRIPTION FACTORS IN PROSTATE CANCER CELLS.
Renty Franklin, Jing Zou, and Leslie Costello.
University of Maryland, Baltimore (Baltimore, USA)
15:15 2.S04
EFFECTS OF SELENIUM ALONE AND WITH ANTIOXIDANTS AND IBUPROFEN MIXTURE IN CHERNOBYL CATASTROPHE CLEAN-UP WORKERS AT RISK OF DEVELOPING CANCER.
Andrejs Skesters1, Tija Zvagule2, Liga Larmane1, Kim Rainsford3, Alise Silova1, Nina Rusakova1, and Pavels Mustafins1.
1Riga Stradin's University (Riga, Latvia); 2 P. Stradins Clinical University Hospital (Riga, Latvia); 3Sheffield Hallam University (Sheffield, United Kingdom)
15:30 2.S05
ARE PEOPLE WITH LOW SELENIUM AND ANTIOXIDANT STATUS AT MUCH HIGHER RISK OF CANCER?
Wojciech Wasowicz.
Institute of Occupational Medicine (Lodz, Poland)
15:45 2.S06
ZINC AND SELENIUM STATUS IN PEDIATRIC MALIGNANT LYMPHOMAS.
Ayhan O. Çavdar. Turkish Academy of Sciences (TÜBA) of Trace Element and UNESCO-Satellite Center (Ankara, Turkey)
16:00 Delegate Coffee Break (OLYMPUS)
16:30 2.S07
ANTICANCER ACTIVITY OF SELENIUM-ENRICHED BROCCOLI SPROUTS IN HUMAN PROSTATE CANCER CELL LINES.
Rizky Abdulah1, Kenji Kobayashi1, Ahmad Faried2, Yoko Katsuya1, Tetsuya Otani1, Kazuto Ito3, Kazuhiro Suzuki3, Masami Murakami4, Hiroyuki Kuwano2, and Hiroshi Koyama1.
1Department of Public Health, Gunma University, Graduate School of Medicine (Maebashi, Japan); 2Department of General Surgical Science (Surgery I), Gunma University, Graduate School of Medicine (Maebashi, Japan); 3Department of Urology, Gunma University, Graduate School of Medicine (Maebashi, Japan); 4Department of Clinical Laboratory Medicine, Gunma University, Graduate School of Medicine (Maebashi, Japan)
16:45 2.S08
ADDING IRON TO WHITE TEA MAY DECREASE ITS ANTIOXIDANT CAPACITY IN HUMANS.
Antonis Koutelidakis, Maria Kapsokefalou, Michael Komaitis, and Dionysia Karambela
Agricultural University of Athens (Athens, Greece)
Minisymposium 3--APHRODITE
Chair: Tania Araujo-Jorge
Co-Chair: Muriel Bost
Category 3: Anemias, and Cardiovascular and Pulmonary Diseases
14:30 3.S01
FISH INTAKE, FATTY ACIDS, MERCURY, SELENIUM AND RISK OF MYOCARDIAL INFARCTION – DESIGN OF A PROSPECTIVE CASE-CONTROL STUDY.
Maria Wennberg1, Ingvar Bergdahl1, Mats Eliasson2, Göran Hallmans3, Ulf Strömberg4, Staffan Skerfving4, Thomas Lundh4, Bengt Vessby5, and Jan-Håkan Jansson3.
1Occupational Medicine (Umeå, Sweden); 2Department of Medicine, Sunderby Hospital (Luleå, Sweden); 3Public Health and Clinical Medicine, Umeå University (Umeå, Sweden); 4Occupational and Environmental Medicine, University Hosptial (Lund, Sweden); 5Public Health and Caring Science, Uppsala University (Uppsala, Sweden)
14:45 3.S02
EFFECT OF SELENIUM SUPPLEMENTATION ON HEART LESIONS PRODUCED BY NEUROLEPTICS.
Muriel Bost1,2, Violette Maffre3, Fanny Vaillant3, Bernard Bui-Xuan3, Alain Tabib4, Jacques Descotes5, Guy Chazot1, Quadiri Timour3,5.
1Trace Element - Institute for UNESCO (Lyon, France); 2Laboratoire d'Analyse de Trace, UF 21303, Biochimie, Hôpital Edouard Herriot (Lyon, France); 3Laboratoire de Pharmacologie Médicale, INSERM ERI 22, Université Claude Bernard Lyon I (Lyon, France); 4Institut de Médecine Légale (Lyon, France); 5Centre Antipoison - Centre de Pharmacovigilance (Lyon, France)
15:00 3.S03
MICRONUTRIENT TREATMENT IMPROVES CARDIAC DAMAGE IN MICE INFECTED WITH TRYPANOSOMA CRUZI.
Tania Araujo-Jorge1, Andrea P de Souza2, Monica Melo-Medeiros2, and Maria-Teresa Rivera2.
1Fundação Oswaldo Cruz (Rio de Janeiro, Brazil); 2Instituto Oswaldo Cruz (Rio de Janeiro, Brazil)
Category 7: Infectious Diseases and Immune Disorders
15:15 7.S01
EFFECTS OF COCKTAIL ANTIOXIDANT SUPPLEMENTATION ON OXIDATIVE STRESS IN AIDS.
Tuomas Westermarck1, Melita Sauka2, Guntar Selga2, Andrzej Skesters3, and Faik Atroshi4. 1Rinnekoti Research Center (Espoo, Finland); 2Institute of Sport Medicine (Riga, Latvia); 3Riga Stradins University of Helsinki; 4Pharmacology & Toxicology, ELTDK, University of Helsinki (Helsinki, Finland)
15:30 7.S02
CURRENT CLINICAL PRACTICES FOR TRACE ELEMENTS SUPPLEMENTATION IN FRENCH BURN CENTRES.
Yves Chancerelle1, Sophie Spadoni2, Laurence Touvard1, Herve Carsin3, and Diane Agay1.
1CRSSA (La Tronche, France); 2ESSA (Bron, France); 3CTB Percy (Clamart, France)
15:45 7.S05
ADDING IRON TO ZINC REDUCED THE EFFICACY OF ZINC ON SERIOUS ADVERSE HEALTH OUTCOMES AMONG PRE-SCHOOL CHILDREN IN MALARIA ENDEMIC ISLAND OF PEMBA.
Sunil Sazawal1, Robert Black1, Usha Dhingra1, Girish Hirmat1, Mahdi Ramsaan2, and Fatma Mohammad3.
1Johns Hopkins University (Baltimore, USA); 2PHL-IDC Pemba (Pemba, Tanzania, United Rep. of); 3Amref (Dar, United Rep. of Tanzania)
16:00 Delegate Coffee Break (OLYMPUS)
16:30 7.S04
IRON HOMEOSTASIS IS CHANGED IN CHLAMYDOPHILA PNEUMONIAE INFECTED TISSUES.
Marie Edvinsson, Peter Frisk, Eva Hjelm, Goran Friman, Christina Nystrom-Rosander, and Nils-Gunnar Ilback. Uppsala University (Uppsala, Sweden)
17:30-18:30 PENTE
ISTERH Officers and Councilors Meeting 1
Officers: Curtiss Hunt (President), Monica Nordberg (Vice-President), Hiroko Kodama (Secretary), Harold Sandstead (Immediate Past-President). Councilors: Jan Aaseth (NORWAY), Mohamed Abdulla (SWEDEN), Muriel Bost (FRANCE), George Brewer (USA) Ayhan Cavdar (TURKEY), Jeanne Freeland-Graves (USA),Rosalind Gibson (New Zealand), Forrest Nielsen (USA), Anne Roussel (FRANCE), Swapan Kumar Roy (BANGLADESH), Manuel Ruz (CHILE), Hiramu Sakurai (JAPAN), Songsak Srianujata (THAILAND), Yoji Takagi (JAPAN), Neil Ward (UNITED KINGDOM), Leslie Woodhouse (USA)
18:00 Monday posters removed from boards in OLYMPUS
___________________________________________________
TUESDAY MORNING, October 23
7:00 Ancillary Function Breakfast
By invitation: Scientific Committee on the Toxicology of Metals, International Commission on Occupational Health (SCTM/ICOH)
7:30 Foyer
Registration
7:30 OLYMPUS
Speaker Ready Room
8:00 OLYMPUS
Commercial Exhibits
9:00-10:00 MINOS
Plenary Session #2, Part A: RAULIN AWARD lecture
Chair: George Brewer
(ISTERH/NTES/HTES '07 acknowledges the generous support from the LABCATAL PHARMACEUTICAL)
Purpose of Session: Primary zinc deficiency, “highly unlikely” in 1959, now common, impairs gene expression and health of progeny. The essentiality of Zn for reproduction is known from experiments in model systems that began more than 50 years ago, and observations on humans that began more than 30 years ago. From this background it is clear Zn deficiency increases risk of abortion, teratology, fetal-stunting, prematurity, and residual functional abnormalities. That there is a problem in the USA, is suggested by the similar associations of iron (Fe) and Zn nutriture with food choices. Zinc is one of several micronutrients essential for metabolic imprinting that affects later health involves epigenetic mechanisms. Given the world prevalence of Zn deficiency, conservatively estimated at 20.5%, the contribution of developmental Zn nutriture to human health in later life begs clarification and application. At the same time, research is needed for understanding of how Zn nutriture affects metabolic imprinting in isolated cells, other species, and humans.
9:00 "Zinc nutriture and fetal origins of disease”, Harold H. Sandstead
Presentation of Raulin Award by Catherine Suck, President of Labcatal Pharmaceutical
10:00-12:00 MINOS
Plenary Session #2, Part B: Trace element nutrition and dietary recommendations
Chair: Jeanne Freeland-Graves
Co-Chair: Rebecca Costello
Purpose of Session: Speakers in this session have worked with dietary requirements, international nutrition and dietary standards. Methods of development of dietary standards vary significantly throughout the world, from emphasis on prevention of deficiency diseases to optimal health. This symposium will make a global comparison of dietary standards of trace elements in developed, transitional and developing countries. Future needs for dietary standards in terms of new trace elements to be considered, as well as changes needed because of new scientific findings, will be a focus of this presentation.
10:00 "The relevance of trace element nutrition in human health”, Sophie Ermidou-Pollet
10:30 Delegate Coffee Break (OLYMPUS)
11:00 "International dietary standards for trace elements”, Jeanne Freeland-Graves
11:30 "Future dietary standards for trace elements”, Lindsay Allen
TUESDAY AFTERNOON, October 23
12:30 Boarding buses at the Creta Maris Hotel for excursion to Palace of Knossos.
Box lunch covered in registration fee; please inform the Secretariat whether you plan to participate
18:00 Return to Creta Maris Hotel
Remainder of evening free
___________________________________________________
WEDNESDAY MORNING, October 24
7:30 FOYER
Registration
7:30 OLYMPUS
Speaker Ready Room
8:00 OLYMPUS
Wednesday posters open. Presentation time: 13:30-14:30
8:00 OLYMPUS
Commercial Exhibits
9:00-12:00 MINOS
Plenary Session #3: Trace Element Speciation
Chair: Yngvar Thomassen
Co-Chair: Ryszard Lobinski
Purpose of Session: This symposium presents the state of the art view on the importance of element speciation in the understanding and rationalization of the biological chemistry and toxicity of elements. The feasibility of speciation depends mainly on the capability to identify and determine element species and to demonstrate that species measurement represents a clear improvement compared to total element determination. The determination of the concentrations of separate and unique atomic and molecular forms of an element instead of its total concentration in a sample, is now a frequent exercise in many scientific disciplines. It has become important in human biology, nutrition, and toxicology - in clinical practice more generally it has yet to do so. The symposium will discuss examples of several areas in which considering speciation has contributed to our understanding of the interaction of metal and metalloid elements with the human organism.
9:00 "Challenges in trace metal speciation of workroom air exposures”, Yngvar Thomassen
9:30 "Analytical challenges to human trace element speciation”, Ryszard Lobinski
10:00 "Studies on the biotransformation of arsenic and selenium in humans”, Kevin Francesconi
10:30 Delegate Coffee Break (OLYMPUS)
11:00 "Purification and identification of low molecular fraction of selenium species in liver cytosol by high performance liquid chromatography and tanem mass spectrometric techniques”, Ying Lu and Spiros A. Pergantis
11:30 "Arsenic biomonitoring in children playing on chromated copper arsenate-treated playgrounds”, Kristi Lew, Jason Acker, and X. Chris Le
12:00-13:30
Delegate Lunch (on your own)
12:00-13:30 PENTE
ISTERH Officers and Councilors Meeting 2
Officers: Curtiss Hunt (President), Monica Nordberg (Vice-President), Hiroko Kodama (Secretary), Harold Sandstead (Immediate Past-President). Councilors: Jan Aaseth (NORWAY), Mohamed Abdulla (SWEDEN), Muriel Bost (FRANCE), George Brewer (USA) Ayhan Cavdar (TURKEY), Jeanne Freeland-Graves (USA),Rosalind Gibson (New Zealand), Forrest Nielsen (USA), Anne Roussel (FRANCE), Swapan Kumar Roy (BANGLADESH), Manuel Ruz (CHILE), Hiramu Sakurai (JAPAN), Songsak Srianujata (THAILAND), Yoji Takagi (JAPAN), Neil Ward (UNITED KINGDOM), Leslie Woodhouse (USA)
WEDNESDAY AFTERNOON, October 24
13:30-14:30 OLYMPUS
POSTER SESSION 2
Category 3: Anemias, and Cardiovascular and Pulmonary Diseases
Chair: Dale Schuschke
P-1 3.P01 BLOOD ANTIOXIDANT MARKERS AND ELEMENTAL LEVELS IN AZOREAN PATIENTS WITH CORONARY ARTERY DISEASE: A PRELIMINARY STUDY.
Rita Ferin1, Patrícia Napoleão2, Carla Gomes1, Ana Rita Castro1, Paula Alexandra Lopes3, Dinis Martins4, Maria Cristina Santos5, José Baptista1, Ana Maria Viegas-Crespo3, Teresa Pinheiro2, and Maria Leonor Pavão1.
1CIRN, Universidade dos Açores (Ponta Delgada, Portugal); 2ITN (Lisboa, Portugal); 3CBA, Universidade dos Açores (Lisboa, Portugal); 4Hospital do Divino Espirito Santo (Ponta Delgada, Portugal); 5DQB, Universidade de Lisboa (Lisboa, Portugal).
P-2 3.P02 BLOOD TRACE ELEMENT LEVELS IN PATIENTS WITH STABILIZED ATHEROSCLEROSIS.
Ana Maria Viegas Crespo1, Patrícia Napoleão1, Paula Lopes1, Maria Cristina Santos1, Maria Leonor Pavão2, and Maria Teresa Pinheiro3.
1Faculdade de Cíências, Universidade Lisboa (Lisboa, Portugal); 2CIRN, Universidade dos Açores (Ponta Delgada, Portugal); 3Instituto Tecnológico e Nuclear (Lisboa, Portugal)
P-3 3.P03 MAGNESIUM IN THE SERUM OF PATIENTS TREATED SURGICALLY.
J. Krystyna Sadlik1, Zbigniew Kopański2, Wojciech Piekoszewski1, and Małgorzata Schlegel-Zawadzka3.
1Institute of Forensic Research (Kraków, Poland); 2Department of Oncological Surgery, Military ClinicalHospital (Kraków, Poland); 3Department Human Nutrition, Faculty of Health Care, Jagiellonian University (Kraków, Poland)
P-4 3.P04 STUDENT TRAVEL COMPETITION AWARDEE: ZINC DEFICIENCY DECREASES ERYTHROPOIESIS IN RATS: IMPLICATION FOR POSSIBLE ZINC DEFICIENCY ANEMIA IN HUMANS.
Aki Konomi, and Katsuhiko Yokoi.
Seitoku University Graduate School (Matsudo, Japan)
P-5 3.P05 HIGH-DOSE ZINC TO TERMINATE ANGINA PECTORIS: A REVIEW AND HYPOTHESIS FOR ACTION BY ICAM INHIBITION.
George Eby1, and William Halcomb2.
1George & Patsy Eby Foundation (Austin, TX, USA); 2William W. Halcomb Clinic (Mesa, AR, USA)
P-6 3.P06 LIPIDEMIC PROFILE AND HEAVY METAL BODY BURDEN IN HYPERTENSIVE PATIENTS.
Spyridoula Mila, Demetra Filiou, Alexandros Tselepis, Angelos Evangelou, and Vasiliki. Kalfakakou
University (Ioannina, Greece)
Category 4: Diabetes Mellitus, Metabolic Syndrome X, and Obesity
Chair: Richard Anderson
P-7 4.P01 THE ROLE OF LOW DOSES OF LEAD ON DEVELOPMENT OF DISLIPIDEMY: EXPERIMENTAL DATA.
Kostiantyn Kozlov, Lilia Krasnokutska, Inna Lubyanova, Nataliya Dmytrukha, Tamara Korolenko, and Iryna Andrusyshyna.
Institute for Occupational Health (Kiev, Ukraine)
P-8 4.P02 IS PLASMA CHROMIUM CONCENTRATION A PREDICTOR FOR FAVOURABLE EFFECT OF CHROMIUM SUPPLEMENTATION?
Matjaz Vrtovec1, Alenka Briski1, Gaj Vidmar2, and Andreja Kocijancic3.
1University Medical Centre (Ljubljana, Slovenia); 2Medical Faculty Ljubljana (Ljubljana, Slovenia); 3University of Ljubljana (Ljubljana, Slovenia)
P-9 4.P03 LONGITUDINAL HAIR-ZN PROFILES OF ELDERLY SUBJECTS WITH NORMAL GLUCOSE TOLERANCE AND TYPE II DIABETES MELLITUS.
Janez Štupar1, Franci Dolinšek2, and Matjaž Vrtovec3.
1University of Nova Gorica (Nova Gorica, Slovenia); 2Retired (Ljubljana, Slovenia); 3University Medical Center (Ljubljana, Slovenia)
P-10 4.P04 INVOLVEMENT OF MACRO AND TRACE ELEMENTS IN DYSREGULATORY MECHANISMS OF OBESITY AND TYPE II DIABETES PATHOGENESIS IN PRE- AND POSTMENOPAUSAL WOMEN.
Margarita Skalnaya1, Georgy Kryzhanovsky2, and Anatoly Skalny2.
1ANO “Centre for Biotic Medicine” (Moscow, Russian Federation); 2Institute of General Pathology and Pathophysiology RAMS (Moscow, Russian Federation)
P-11 4.P05 DETERMINATION OF HEAVY METALS AND TRACE METALS IN GROUND WATER AND SOIL IN LYBIA BY FLAME AAS AND HEART AND DIABETICS DISEASES.
Tarik Nasser1, Ali Alagel2, Mohamed Emhemed2, and Ahmedf Alhaqngari2. 1Almerqeb University (Tripoli, Lybia); 2National Center of Pesticides (Tripoli, Lybia)
P-12 4.P06 AGES AND COPPER IONS.
Andreea Iren Serban Capatina1, Marieta Costache2, and Anca Dinischiotu2.
1University of Agricultural Science and Veterinary Medicine, Faculty of Veterinary Medicine (Bucharest, Romania); 2University of Bucharest, Faculty of Biology, Molecular Biology Center (Bucharest, Romania)
Category 5: Disorders of Aging
Chair: Mohamed Abdulla
P-13 5.P01 ELEMENTS IN HAIR OF POPULATION WITH DIFFERENT GRADE OF HYPOTHYROIDISM.
Tatjana Lalic1, and Ivana Djujic2.
1"Balans Medika", Center for Balanced and High Quality Live (Belgrade, Serbia and Montenegro); 2University of Belgrade,ICHTM-Department of Chemistry (Belgrade, Serbia and Montenegro)
P-14 5.P02 THE CONSEQUENCES OF ALUMINIUM EXPOSURE ON RATS GENITAL ORGANS AND SEXUAL ACCESSORY GLAND HISTOARCHITECTURE: THREE GENERATION EXPERIMENT.
Alexandra Trif, Florin Muselin, and Diana Argherie.
Faculty of Veterinary Medicine Timisoara (Timisoara, Romania)
P-15 5.P03 AGE-RELATED ANTIOXIDANT DEFENSE WEAKENING IS ALTERED BY LOW SELENIUM INTAKES.
Irini Margaritis1, Isabelle Hininger-Favier2, Adrien Botta3, and Luc Farout3.
1French Food Agency (Maisons-Alfort, France); 2Université de Grenoble I (Grenoble, France); 3Université de Nice Sophia-Antipolis (Nice, France)
P-16 5.P04 THE CONSEQUENCES OF FEMALE RATS EXPOSURE TO LEAD ACETATE ON SOME SEXUAL HORMONES.
Eugenia Dumitrescu, Alexandra Trif, and Florin Muselin.
Faculty of Veterinary Medicine Timisoara (Timisoara, Romania)
P-17 5.P05 THE CONSEQUENCES OF FEMALE RATS EXPOSURE TO ALUMINUM SULPHATE ON SOME SEXUAL HORMONES.
Alexandra Trif, Eugenia Dumitrescu, and Florin Muselin.
Faculty of Veterinary Medicine Timisoara (Timisoara, Romania)
P-18 5.P06 THE CONSEQUENCES OF LEAD EXPOSURE ON RATS GENITAL ORGANS AND SEXUAL ACCESSORY GLANDS HISTOARCHITECTURE: THREE GENERATION EXPERIMENT.
Florin Muselin, Alexandra Trif, and Diana Argherie.
Faculty of Veterinary Medicine Timisoara (Timisoara, Romania)
Category 6: Fetal Development and Pediatric Disorders
Chair: Lars Barregård
P-19 6.P01 LEVELS OF TOXIC HEAVY METALS AND ESSENTIAL TRACE ELEMENTS IN MATERNAL BLOOD, CORD BLOOD, AND PLACENTAL TISSUES IN JAPANESE PREGNANT WOMEN.
Satomi Kameo1, Kunihiko Nakai2, Miyuki Shimada2, Keita Suzuki2, Kozue Sakurai2, Naoyuki Kurokawa2, and Hiroshi Satoh2.
1Tohoku University Graduate School of Medicine (Sendai, Japan); 2Environmental Health Sciences, Tohoku University Graduate School of Medicine (Sendai, Japan)
P-20 6.P02 IMPAIRMENT OF IODINE AND THYROID HORMONES METABOLISM IN VERY PREMATURE INFANTS.
Stanislav Pavelka. Faculty of Science, Masaryk University, Brno, and Institute of Physiology, Czech Acad. Sci., (Prague 4, Czech Republic)
P-21 6.P03 CADMIUM EXPOSURE AND TRACE ELEMENTS IN BREAST MILK.
Maria Kippler1, Bo Lönnerdal2, Walter Goessler3, Eva-Charlotte Ekström4, Lars-Åke Persson4, Shams El Arifeen5, and Marie Vahter6.
1Karolinska institute (Stockholm, Sweden); 2Nutritional and Internal Medicine, University of California (Davis, USA); 3Institut für Chemie – Analytische Chemie, Karl-Franzens-Universität (Graz, Austria); 4International Maternal and Child Health, Uppsala University (Uppsala, Sweden); 5International Centre for Diarrhoeal Disease Research (ICDDR,B) (Dhaka, Bangladesh); 6Institute of Environmental Medicine, Karolinska Institute (Stockholm, Sweden)
P-22 6.P04 COPPER AND ZINC STATUS IN THE BREAST MILK OF MOTHERS WITH WILSON’S DISEASE.
Katsuaki Shiga1, Fumiaya Kaga1, Chie Fujisawa1, Yanhong Gu1, Kenji Kobayashi2, Hiroshi Koyama2, and Hiroko Kodama1.
1Teikyo (Tokyo, Japan); 2Gunma (Gunma, Japan)]
P-23 6.P05 ANALYSIS OF SOME IMPORTANT TRACE ELEMENTS IN THE PLACENTAS OF HEALTHY AND PREECLAMPTIC TURKISH WOMEN IN THE PROVINCE OF KAYSERI-TURKEY.
Nalan Ozdemir, Zeliha Leblebici, Berkay Saraymen, Burak Saraymen, Recep Saraymen, and Ahmet Acer.
Erciyes University (Kayseri, Turkey)
P-24 6.P06 STUDENT TRAVEL COMPETITION AWARDEE: EFFECT OF ONE YEAR OF IRON/ZINC FORTIFICATION ON LEAD LEVELS AMONG CHILDREN AGED 1-4 YEARS.
Usha Dhingra1, Saikat Deb1, Venugopal P Menon2, Robert E Black1, Pratibha Dhingra2, Archana Sarkar2, and Sunil Sazawal1.
1Johns Hopkins Univeristy (Baltimore, USA); 2Center for Micronutrient Research, Annamalai Univerity (New Delhi, India); 3Center for micronutrient Resaerch, Annamalai University (New Delhi, India)
P-25 6.P07 NUTRITIONAL VALUE OF PROCESSED VS. TRADITIONAL SNACKS, CONSUMED BY CHILDREN, IN RELATION TO THEIR ZN AND CU CONTENT.
Demetra Filiou, Spyridoula Mila, Panagiotis Gorezis, Vasilios Koutras, Angelos Evangelou, and Vasiliki. Kalfakakou
University (Ioannina, Greece)
P-26 6.P08 EXPOSURE ASSESSMENT OF METHYLMERCURY IN THE JAPANESE PREGNANT WOMEN.
Hiroshi Satoh1, Miyuki Shimada2, Takashi Ohba2, Satomi Kameo2, Keita Suzuki3, Kozue Sakurai2, Naoyuki Kurokawa2, Katsuyuki Murata4, Mineshi Sakamoto5, and Kunihiko Nakai2.
1Tohoku University Graduate School of Medicine (Sendai, Japan); 2Environmental Health Sciences, Tohoku University Graduate School of Medicine (Sendai, Japan); 3Human Development and Disabilities, Tohoku University Graduate School of Education (Sendai, Japan); 4Environmental Health Sciences, Akita University School of Medicine (Akita, Japan); 5Epidemiology, National Institute for Minamata Disease (Minamata, Japan)
P-27 6.P09 IODINE DEFICIENCY DISORDERS IN MARRAKECH, MOROCCO.
Azeddine SEDKI1, Farida Zaida2, Nadra Lekouch2, Dominique Bougle2, and Pierre Ahran2.
1Satellite Centre of Trace Element - Institute for UNESCO (Marrakech, Morocco); 2Satellite Centre of Trace Element - Institute for UNESCO: Morocco, Dept of Biology, Faculty of Sciences (Marrakech, Morocco); 3Digestive and Nutritional Physiology Laboratory, CHU (Caen, France)
Category 7: Infectious Diseases and Immune Disorders
Chair: Manuel Ruz
P-28 7.P01 TISSUE UPTAKE OF MERCURY IS CHANGED DURING THE COURSE OF A COMMON VIRAL INFECTION IN MICE.
Peter Frisk1, Ylva Molin2, and Nils-Gunnar Ilbäck3.
1Research in Metal Biology (Uppsala, Sweden); 2Department of Medical Sciences, Infectious Diseases, Uppsala University Hospital (Uppsala, Sweden); 3Department of Medical Sciences, Infectious Diseases, Uppsala University Hospital and Toxicology Division, National Food Administration, Uppsala (Uppsala, Sweden)
P-29 7.P02 ZINC TREATMENT PREVENTS DYSMENORRHEA.
George Eby
George & Patsy Eby Foundation (Austin, USA)
P-30 7.P03 EVALUATION OF THE OXIDANT/ANTIOXIDANT STATUS IN PATIENTS WITH BEHÇET’S DISEASE.
Olfa Harzallah1, Tarek Baati2, Sylvia Mahjoub3, and Abdelhamid Kerkeni2.
1Internal medicine department; Fattouma Bourguiba hospital (Monastir, Tunisia); 2Biophysics laboratory; Medicine Faculty (Monastir, Tunisia)
P-31 7.P04 ANEMIA, IRON DEFICIENCY, AND PARASITISM IN CHILDREN FROM A RURAL COMMUNITY OF VENEZUELA.
Zully Benzo1, Jham Papale2, Manuelita Quintal1, Yelitza Berne2, Mario Torres2, Ester Gimenez2, Manuel Castro2, and Zuly Briceño3.
1IVIC (Caracas, Venezuela); 2Decanato de Medicina. Laboratorio de Bioquimica Nutricional. Universidad Centroccidental Lisandro Alvarado (Barquisimeto, Venezuela); 3Decanato de Ciencia y Tecnologia. Laboratorio de Bioquimica Nutricional. Universidad Lisandro Alvarado. (Barquisimeto, Venezuela)
P-32 7.P05 ZINC AND COPPER IN RED BLOOD CELLS, LIPID PEROXIDATION , NUTRITIONAL STATUS, AND INFLAMMATORY RESPONSE IN THE PROGRESSION OF CHRONIC HEPATITIS C VIRUS INFECTION.
Emilio González-Reimers1, Ana Castellano-Higuera1, Remedios Alemán-Valls1, Pedro Abreu-González2, Luis Galindo-Martín3, Candelaria Martín-González1, Francisco Santolaria-Fernandez1, and Juan Luis Gómez-Sirvent1.
1Hospital Universitario (La laguna/Tenerife, Spain); 2de Medicina (La Lagune, Spain); 3Facultad de Quimíca (La Lagune, Spain)
P-33 7.P06 INFLUENCE OF TOXIC AND ESSENTIAL METALS ON MARKERS OF ATOPY AND VENTILATORY FUNCTION IN MEN AND WOMEN.
Alica Pizent, Jelena Macan, Jasna Jurasović, Veda Marija Varnai, and Božica Kanceljak Macan.
Institute for Medical Research and Occupational Health (Zagreb, Croatia)
P-34 7.P07 CAN LEG DISORDERS OF TURKEYS BE PREVENTED BY SOME EFFECTIVE INGREDIENTS CONTAINING THE FEED ADDITIVE IMMUNOVET-HBMTM? .
Nagy Gyula, Kosa Emma, and Jakab Laszlo. Szent Istvan University, Faculty of Veterinary Science (Budapest, Hungary)
P-35 7.P08 INFLUENCE OF SELENIUM AND EIMERIA TENELLA INFECTION ON ANTIOXIDANT STATUS IN CHICKS: STATUS AND RESISTANCE AGAINST INFECTIONS.
Sophie Ermidou-Pollet1, Margarita Gabrashanska2 , V. Koinarski3, St. Denev4, Serge Pollet5, and M. Anisimova2.
1University of Athens (Nea-Makri, Greece); 2Institute of Experimetal Pathology and Parasitology, Bulgarian Academy of Sciences (Sofia, Bulgaria); 3Faculty of Veterinary Medicine, Trakia University (Stara Zagora, Bulgaria); 4Faculty of Agriculture, Trakia University (Stara Zagora, Bulgaria); 5HTES (Athens, Greece)
Category 8: Molecular Nutrition for the Clinician
Chair: James Kang
P-36 8.P01 THE EFFECT OF SELENIUM SUPPLEMENTATION TO HEMODIALYSIS PATIENTS ON PLASMA GLUTATHIONE PEROXIDASE (GSH-PX) ACTIVITY AND GSH-PX PROTEIN LEVEL.
Bronislaw Zachara1, Jolanta Gromadzinska1, Zbigniew Zbrog2, Rafal Swiech2, Ewa Jablonska1, Ewa Twardowska1, and Wojciech Wasowicz1.
1Institute of Occupational Medicine (Lodz, Poland); 2B. Braun Avitum Dialysis Center (Lodz, Poland)
P-37 8.P02 MOLECULAR DIAGNOSIS FOR ATYPICAL PATIENTS AND CARRIERS WITH WILSON DISEASE.
Junko Fujiwara, Norikazu Shimizu, Horomichi Hemmi, and Tsugutoshi Aoki.
Toho University (Tokyo, Japan)
P-38 8.P03 ROLE OF ZN IN ROPIVACAINE AND NEUTRAL ENDOPEPTIDASE: TOXIC EFFECTS ON HUMAN CERATINOCYTE CELLS.
Evangelos Kontargiris, Evangelos Kolettas, Athina Vadalouca, and Vasiliki Kalfakakou.
University (Ioannina, Greece)
Category 10: Osteoporosis and Other Bone Disorders
Chair: Scott Smith
P-39 10.P01 THE EFFECTS OF LOW-LEVEL CADMIUM EXPOSURE ON BONE DENSITY. Malgorzata Trzcinka-Ochocka, Marek Jakubowski, and Beata Janasik.
Nofer Institute of Occupational Medicine (Lodz, Poland)
P-40 10.P02 EFFECTS OF DIETARY COMPONENTS ON CADMIUM-IINDUCED BONE LOSS IN AN OVARIECTOMIZED RAT MODEL OF OSTEOPOROSIS. Barbara Stoecker1, Amani Soliman1, Do You Soung2, Latha Devareddy3, and Bahram Arjmandi3.
1Oklahoma State University (Stillwater, USA); 2University of Rochester (Rochester, NY, USA); 3Florida State University (Tallahassee, FL, USA)
P-41 8.P04 STRONG INDUCTION OF ARACHIDONATE 12-LIPOXYGENASE (ALOX15) IN THE INTESTINE OF IRON-DEFICIENT RATS RESULTS IN THE PRODUCTION OF BIOLOGICALLY ACTIVE LIPID MEDIATORS. James Collins, Zihua Hu, Michael Garrick, Laura Garrick, and Richard Browne.
University at Buffalo, the State University of New York (Buffalo, USA)
P-42 Open.
P-43 10.P05 DOES CALCIUM SUPPLEMENTATION DURING THE SUCKLING PERIOD AFFECT BONE MINERAL DENSITY AND BONE ZINC LATER IN ADULT RATS?.
Veda Marija Varnai1, Martina Piasek1, and Marijana Matek Saric2.
1Institute for Medical Research and Occupational Health (Zagreb, Croatia); 2Institute for Public Health Zadar (Zadar, Croatia)
P-44 10.P06 THE FEASIBLE USE OF TEETH AS THE SITE FOR THE IN VIVO QUANTIFICATION OF STRONTIUM BY X-RAY FLUORESCENCE SPECTROMETRY.
Eric Da Silva1, Ana Pejovic-Milic2, and Darrick V. Heyd3.
1Ryerson University (Toronto, Canada); 2Ryerson University, Department of Physics (Toronto, Canada); 3Ryerson University, Department of Chemistry & Biology (Toronto, Canada)
P-45 10.P07 TRACE ELEMENT CONCENTRATIONS IN HUMAN NAILS USING ATOMIC ABSORPTION SPECTROMETRY.
Fathi El-Amri1, Ramadan damja2, and Yousf Benshaban2.
1United Arab Emirates University (Al-Ain, United Arab Emirates); 2al-Fateh University, Tripoli, Libya (Tripoli, Libya)
P-46 10.P08 ELIMINATION OF ARTHRITIS PAIN AND INFLAMMATION FOR OVER 2 YEARS WITH A SINGLE 90 MIN, TOPICAL 14% GALLIUM NITRATE TREATMENT: CASE REPORTS AND REVIEW OF ACTIONS OF GALLIUM III.
George Eby.
George & Patsy Eby Foundation (Austin, USA)
P-47 10.P09 THE ASSESSMENT OF THE EFFECT OF CALCIUM, MAGNESIUM, AND VIT D SUPPLEMENTATION BY THE HAIR MULTIELEMENT PROFILE FOLLOW UP.
Juraj Prejac, Nikola Ivicic, and Berislav Momcilovic.
Institute for Medical Research and Occupational Health (IMI) (Zagreb, Croatia)
14:30-17:30 Five Concurrent Sessions (Symposia C, D, and E; Minisymposium 4 and 5)
Symposium C--MINOS
Environmental Stress and Mineral Homeostasis
Chair: James McClung
Purpose of Session: Mineral homeostasis is vulnerable to a variety of environmental stressors including heat, altitude, and weightlessness. The symposium summarizes current understanding of the effect environmental stress on human physiology. This includes discussion of the effects of physical training on mineral loss (with emphasis on perturbations of iron and zinc metabolism); hypobaric pressure on mineral dependent enzymes; and weightlessness on bone demineralization and calcium metabolism.
14:30 "Overview of human physiological responses to environmental extremes”, Andrew Young
15:00 "Iron Homeostasis in Environmental Extremes”, James McClung
15:30 "Mineral homeostasis at high altitude: focus on antioxidants”, Andrew Subudhi
16:00 Delegate Coffee Break (OLYMPUS)
16:30 "Mineral homeostasis during spaceflight: bone demineralization”, Scott Smith
17:00 "Mineral losses during extreme environmental conditions”, Henry C. Lukaski
Symposium D--ATHENA-ARTEMIS
Molecular mechanisms of metal induced disease
Chair: Max Costa
Co-Chair: Michael Aschner
Purpose of Session: Environmental exposure to excessive concentrations of trace minerals lead to significant morbidity and mortality. However, there is little understanding of the molecular mechanisms responsible for metal-induced disease. This symposium summarizes progress made in understanding some of those molecular mechanisms. It will emphasize new findings that the stabilization of HIF-1 alpha and histone methylation contribute to nickel ion carcinogenicity. Also, that any change in dietary iron levels exacerbates brain manganese accumulation and alters normal brain iron distribution in multiple discrete brain regions.
14:30 "Changes In Dietary Iron Levels Affect Brain Manganese accumulation and distribution”, Michael Aschner
15:00 "Molecular Carcinogenicity of Nickel Ions targets HIF-1 Prolyl Hydroxylases and Histone-3 Lysine 9 Demethylases”, Max Costa
15:30 "Reprogramming of histone marks by chromium”, Michael Schnekenburger, Li Peng, and Alvaro Puga
16:00 Delegate Coffee Break (OLYMPUS)
16:30 "Arsenic cardiomyopathy and molecular mechanism”, Y. James Kang
Symposium E--EUROPA-DANAE
Advances in Analytical Detection of Trace Elements in Biological Tissues
Chair: Sophie Ermidou-Pollet
Co-Chair: Edouard Jallot
Co-Chair: Maria Luisa de Carvalho
Co-Chair: Enrico Sabbioni
Purpose of Session: Progress in trace element research depends very much on the use of appropriate methodologies and their improvement. The progressive availability of new physical methods have very much increased the possibilities for quantitative and local (including subcellular) studies of chemical elements in biological systems.
The recent improvements in the methods of detection and their application in nutrition and medicine, as well as the problems associated with the determination of trace elements will be presented during this session by “high level” scientist speakers having great experiences in these fields.
14:30 "Ion and electron beams methods for biological trace element characterization at bioceramics/cells interface”, Edouard Jallot
15:00 "X-ray fluorescence technique on trace element determination in biological samples”, Maria Luisa de Carvalho
15:30 "Alternative testing methods in food nanoparticles toxicology research for a safe food nanotechnology development”, Enrico Sabbioni
16:00 Delegate Coffee Break (OLYMPUS)
Minisymposium 4: Category 12--Trace Element Detection and Quantification
16:30 12.S01
SEPARATION OF PROTEINS IN CEREBROSPINAL FLUID BY SIZE EXCLUSION HPLC AND DETERMINATION OF TRACE ELEMENTS BY HR-ICP-MS.
Kristin Gellein1, Per M Roos2, Lars Evje3, Olof Vesterberg4, Trond Peder Flaten5, Monica Nordberg6, and Tore Syversen3.
1Norwegian University of Science and Technology (Trondheim, Norway); 2Department of Neurology, Ullevaal University Hospital (Oslo, Norway); 3Department of Neuroscience, Norwegian University of Science and Technology (Trondheim, Norway); 4Faculty of Natural Sciences, Uppsala University ( Uppsala, Sweden); 5Department of Chemistry, Norwegian University of Science and Technology ( Trondheim, Norway); 6Institute of Environmental Medicine, Karolinska Institutet (Stockholm, Sweden)
16:45 12.S03
VERY ACCURATE (DEFINITIVE) METHODS BY RNAA. THE IDEA AND RECENT ACHIEVEMENTS.
Rajmund S. Dybczynski, Ewelina Chajduk, and Halina Polkowska-Motrenko.
Institute of Nuclear Chemistry and Technology (Warszawa, Poland)
17:00 12.S04
ION SPECTROMETRY (SIMS) AND ELECTRON MICROSCOPY (TEM) CORRELATIVE IMAGING IN THE QUEST OF COMPREHENSIVE TRACE ELEMENT LOCALIZATION AT SUBCELLULAR LEVEL, IN NORMAL AND PATHOLOGICAL KERATINOCYTES.
Eliane Larras-Regard, Jéril Degrouard, and Danielle Jaillard.
Université Paris-Sud (ORSAY, France)
17:15 12.S05
RECENT DEVELOPMENTS IN ICP-MS APPLIED TO STUDIES IN NUTRITION AND HEALTH.
Steven Durrant1, and Neil Ward2.
1Universidade Estadual Paulista (UNESP) (Sorocaba, SP, Brazil); 2University of Surrey (Guildford, United Kingdom)
17:30 12.S06
ELEMENTAL ANALYSIS OF BIOLOGICAL MATERIALS – STATE OF THE ART
Douglas Baxter, and Ilia Rodushkin; ALS Scandinavia (Luleå, Sweden)
Minisymposium 5--LEDA
Chair: Barbara Stoecker
Co-Chair: Vadim Ermakov
Category 4: Diabetes Mellitus, Metabolic Syndrome X, and Obesity
14:30 4.S01
FEMALE OFFSPRING OF RAT DAMS FED LOW BORON DIETS DURING PREGNANCY AND LACTATION EXHIBIT SIGNS OF THE METABOLIC SYNDROME DURING EARLY ADULTHOOD: INCREASED BODY WEIGHT, AND SERUM TRIGLYCERIDES AND TOTAL CHOLESTEROL CONCENTRATIONS.
Curtiss Hunt, and Joseph Idso.
USDA/ARS/GFHNRC (Grand Forks, USA)
14:45 4.S02
SAFETY, ABSORPTION, AND ANTIOXIDANT EFFECTS OF CHROMIUM HISTIDINE.
Richard A. Anderson1, Noella Bryden1, Marilyn Polansky1, Isabelle Hininger-Favier2, Rachida Benaraba2, and Anne Roussel2.
1Beltsville Human Nutrition Research Center (Beltsville, USA); 2LBFA, Universite' Joseph Fourier, (Grenoble I, France)
15:00 4.S03
ZINC AND IRON ABSORPTION AND NUTRITIONAL STATUS AFTER GASTRIC BYPASS IN MORBID OBESE PATIENTS.
Manuel Ruz1, Fernando Carrasco1, Pamela Rojas1, Jorge Inostroza1, Juana Codoceo1, Attila Csendes1, Karin Papapietro1, Fernando Pizarro1, Manuel Olivares1, Nancy Krebs2, Jamie Westcott2, and Michael Hambidge2.
1University of Chile (Santiago, Chile); 2UCHSC (Denver, CO, USA)
Category 6: Fetal Development and Pediatric Disorders
15:15 6.S01
STUDENT TRAVEL COMPETITION AWARDEE: INCREASED CADMIUM ABSORPTION IN IRON SUPPLEMENTED SUCKLING PIGLETS.
Helena Öhrvik1, Agneta Oskarsson1, Thomas Lundh2, Staffan Skerfving2, and Jonas Tallkvist1.
1Swedish University of Agricultural Sciences (Uppsala, Sweden); 2Lund University Hospital (Lund, Sweden)
15:30 6.S02
RED-CELL TRACE MINERALS IN CHILDREN WITH AUTISM.
Joan Jory1, and Woody McGinnis2
1Joan Jory, (Guelph, Canada); 2Woody McGinnis.
(Ashland, Oregon, USA)
15:45 6.S03
CONSUMPTION OF MILK FORTIFIED WITH IRON, ZINC AND TRACE AMOUNTS OF COPPER FOR 1 YEAR: EFFECTS ON COPPER STATUS AMONG PRE-SCHOOL CHILDREN.
Girish Hiremath1, Sunil Sazawal1, Usha Dhingra1, Saikat Deb1, Pratibha Dhingra2, Archana Sarkar2, Venugopal P Menon2, and Robert E Black1.
1Johns Hopkins University (Baltimore, USA); 2Center for Micronutrient Research,Annamalai University (New Delhi, India)
16:00 Delegate Coffee Break (OLYMPUS)
Category 10: Osteoporosis and Other Bone Disorders
16:30 10.S01 RECOVERY OF BONE STATUS AFTER ABANDONING INGESTING CADMIUM-RICE FOR 10 YEARS.
Chen Xiao, Zhu Guoying, Jin Taiyi, Lei Lijian, and Liang Yihuai. Fudan University (Shanghai, China)
16:45 10.S02 SE DEFICIENCY AND MANIFESTATION OF UROV DISEASE IN EAST SIBERIA.
Vadim Ermakov
V.I. Vernadsky Institute of Geochemistry and Analytical Chemistry (Moscow, Russian Federation)
17:00 10.S03 THE BA/SR RATIO, CARIOUS LESIONS, AND DENTAL CALCULUS AMONG THE POPULATION BURIED IN LA CONCEPCIÓN (TENERIFE, CANARY ISLANDS).
Matilde Arnay-de-la-Rosa1, Emilio González-Reimers2, Alejandro Gámez-Mendoza3, and Luis Galindo-Martín4.
1Dpto. de Prehistoria, Antropología e Historia Antigua (La Laguna/Tenerife, Spain); 2Hospital Universiatrio (La Laguna/Tenerife, Spain); 3Facultad de Geografía e Historia (La Laguna/Tenerife, Spain); 4Facultad de Química (La Laguna/Tenerife, Spain)
Minisymposium 6--APHRODITE
Chair: Jan Aaseth
Co-Chair: Magdalena Araya
Category 8: Molecular Nutrition for the Clinician
14:30 8.S01
MUTATION ANALYSIS IN FRENCH WILSON DISEASE PATIENTS: IDENTIFICATION OF PREVALENT SUBSTITUTION AND ELEVEN NOVEL MUTATIONS IN THE ATP7B GENE.
Muriel Bost1,2,3, Guénaelle Piguet-Lacroix2,3, Martine Pelosse3, Rodica Gincul3, Emmanuel Broussolle3,4, Jing Xie-Brustolin3,4, Jérôme Dumortier3,5, Alain Lachaux3,6.
1Trace Element - Institute for UNESCO (Lyon, France); 2Neurogénétique moléculaire, Centre de Biologie, Groupe Hospitalier Est (Lyon, France); 3Centre de Référence Maladie de Wilson, Département de Pédiatrie, Hôpital Edouard-Herriot (Lyon, France); 4Service de Neurologie, Hôpital Neurologique (Lyon, France); 5 Fédération des spécialités digestives, Hôpital Edouard Herriot (Lyon, France); 6 Unité d'Hépatogastroentérologie infantile, Département de Pédiatrie, Hôpital Edouard Herriot (Lyon, France)
14:45 8.S02
IDENTIFICATION OF ATP7A MUTATIONS ASSOCIATED WITH MENKES DISEASE.
Chie Fujisawa1, Hiroko Kodama1, Katsuaki Shiga1, YanHong Gu2, and Fumiaya Kaga1.
1Teikyo University School of Medicine (Tokyo, Japan); 2National Center for Child Health and Development (Tokyo, Japan)
15:00 8.S03
IRON AND COPPER TOXICITY IN HEREDITARY DISEASES.
Jan Aaseth1, Ole Andersen2, Trond Peder Flaten3, and Kristin Gellein3.
1Sykehuset Innlandet (Kongsvinger, Norway); 2Roskilde University (Roskilde, Denmark); 3Norwegian University of Science and Technology (Trondheim, Norway)
15:15 8.S04
DIETARY ORIGIN OF SIMULTANEOUS DEFICIENCY OF ZINC AND IRON IN HUMANS.
Katsuhiko Yokoi1, Harold H. Sandstead2, Norman G. Egger3, Nancy W. Alcock2, V. M. Sadagopa Ramanujam2, Hari H. Dayal2, and James G. Penland4.
1Seitoku University Graduate School (Matsudo, Japan); 2PM&CH, University of Texas Medical Branch (Galveston, TX, USA); 3General Internal Medicine, Mayo Clinic (Rochester, MN, USA); 4Grand Forks Human Nutrition Research Center (Grand Forks, ND, USA)
15:30 8.S05
CHRONIC COPPER TOXICITY IN A NON-HUMAN PRIMATE MODEL: PRELIMINARY RESULTS.
Magdalena Araya, Hector Nuñez, Miguel Arredondo, Fernando Pizarro, Marco Mendez, and Manuel Olivares. INTA, University of Chile (Santiago, Chile)
15:45 8.S06
MECHANISM OF SELENOCYSTEINE LYASE: STRICT DISCRIMINATION BETWEEN SELENIUM AND SULFUR.
Nobuyoshi Esaki, Hisaaki Mihara, and Suguru Kurokawa.
Kyoto University (Uji, Japan)
16:00 Delegate Coffee Break (OLYMPUS)
16:30 8.S07
THE CELLULAR FUNCTION OF SELENOCYSTEINE LYASE IN SELENOPROTEIN SYNTHESIS.
Hisaaki Mihara, Suguru Kurokawa, and Nobuyoshi Esaki.
Kyoto University (Uji, Japan)
16:45 8.S08
STRATEGY OF MOLECULAR DIAGNOSIS FOR WILSON DISEASE IN JAPAN.
Atsuko Watanabe, Norikazu Shimizu, Hiromichi Hemmi, and Tsugutoshi Aoki.
Toho University (Tokyo, Japan)
17:00 8.S09
ROLE OF ZINC TRANSPORTERS IN CADMIUM TRANSPORT IN MAMMALIAN CELLS.
Seiichiro Himeno, and Hitomi Fujishiro.
Tokushima Bunri University (Tokushima, Japan)
17:15 8.S10
MOLECULAR REGULATION OF THE MENKES COPPER ATPASE (ATP7A) AND DIVALENT METAL TRANSPORTER 1 (DMT1) BY IRON IN RAT DUODENUM AND IEC-6 CELLS.
James Collins.
University at Buffalo, the State University of New York (Buffalo, USA)
17:30-20:30 LEDA
MEETING OF UNESCO SATELLITE CENTRE MEMBERS
Chair: Mohamed Abdulla
Trace Element - Institute for UNESCO
Supported by UNESCO
___________________________________________________
THURSDAY MORNING, October 25
7:30 Foyer
Registration
7:30 OLYMPUS
Speaker Ready Room
8:00 OLYMPUS
Thursday posters open. Presentation time: 13:30-14:30
8:00 OLYMPUS)
Commercial Exhibits
9:00-12:00 MINOS
Plenary Session #4: Health Consequences of Trace Element Deficiencies
Chair: Sophie Ermidou-Pollet
Co-Chair: Ivana Djujic
Co-Chair: Manfred Anke
Co-Chair: Maria Kapsokefalou
Purpose of Session: Deficiencies of trace elements have profound effects on the development, health and well being of humans. They may affect human reproduction, the progression of pregnancy and the development of newborns and young children, a very important problem, especially in developing countries.
Diagnosis of deficiency and the monitoring of individuals receiving treatment require the knowledge of both the trace element status of these individuals prior treatment and, in case of deficiency, the trace element requirements needed for restoring an adequate trace element status. The invited speakers are internationally recognized experts or clinicians. Their knowledge, experiences, and qualifications will give to the participants the opportunity to learn about the state-of-art developments in the field of trace element nutrition and human development, both physical and economic.
9:00 “Trace element nutrition: a neglected health issue in developing countries”, Mohamed Abdulla
9:30 "Studies on the placental and mammary gland transfer of trace elements: impact of possible trace element deficiencies in infancy”, Erich Rossipal
10:00 "Trace element deficiency treatment: much more than trace element supplementation”, Ivana Djujic
10:30 Delegate Coffee Break (OLYMPUS)
11:00 "Predicting relative concentrations of bioavailable iron using in vitro approaches”, Maria Kapsokefalou
11:30 "Iodine in the food chain of animals and man: intake, balance and requirement”, Manfred Anke
12:00
Delegate Lunch (on your own)
12:00 PENTE
ISTERH Officers and Councilors Meeting 3
Officers: Curtiss Hunt (President), Monica Nordberg (Vice-President), Hiroko Kodama (Secretary), Harold Sandstead (Immediate Past-President). Councilors: Jan Aaseth (NORWAY), Mohamed Abdulla (SWEDEN), Muriel Bost (FRANCE), George Brewer (USA) Ayhan Cavdar (TURKEY), Jeanne Freeland-Graves (USA),Rosalind Gibson (New Zealand), Forrest Nielsen (USA), Anne Roussel (FRANCE), Swapan Kumar Roy (BANGLADESH), Manuel Ruz (CHILE), Hiramu Sakurai (JAPAN), Songsak Srianujata (THAILAND), Yoji Takagi (JAPAN), Neil Ward (UNITED KINGDOM), Leslie Woodhouse (USA)
THURSDAY AFTERNOON
13:30-14:30 OLYMPUS
POSTER SESSION 3
Category 9: Neurological Diseases & Neuropsychological Impairment
Chair: James Camakaris
Co-Chair: Rosanna Squitti
P-1 9.P01 EFFECT OF VALPROIC ACID TREATMENT ON SERUM CLINICAL AND BLOOD HEMATOLOGICAL VALUES IN EPILEPTIC SUBJECT SUPPLEMENTED WITH SELENIUM AND ANTIOXIDANT COCKTAILS .
Tuomas Westermarck1, Elzbieta Plonka-Poltorak2 and Faik Atroshi3. 1Rinnekoti Research Center (Espoo, Finland); 2Provincial Hospital (Rzeszow, Poland); 3Pharmacol. et Toxicol. Department, University of Helsinki (Helsinki, Finland)
P-2 9.P02 EFFECTS OF COPPER METABOLISM ON BEHAVIORAL FUNCTIONS AND BRAIN MONOAMINE CONTENTS IN WISTAR AND WILSON’S DISEASE MODEL RATS.
Noriko Fujiwara, Hiroyuki Iso, Nobue Kitanaka, Junichi Kitanaka, Daisaku Yoshihara, Tomomi Ookawara, and Keiichiro Suzuki.
Hyogo College of Medicine (Nishinomiya, Japan)
P-3 9.P03
TRACE ELEMENTS IN SERUM FROM PATIENTS WITH PARKINSON’S DISEASE – A PROSPECTIVE CASE-CONTROL STUDY.
Kristin Gellein1, Tore Syversen1, Eiliv Steinnes1, Tom Ivar Lund Nilsen2, Syverin Lierhagen1, Ole Petter Dahl3, Sascha Mitrovic4, Dusan Duraj5, and Trond Peder Flaten1.
1Norwegian University of Science and Technology (Trondheim, Norway); 2Norwegian University of Science and Techology (Trondheim, Norway); 3Namsos Hospital (Namsos, Norway); 4Levanger Hospital (Levanger, Norway); 5Nevrolog Duraj AS (Levanger, Norway)
P-4 9.P04
TRACE ELEMENTS IN CEREBROSPINAL FLUID AND BLOOD FROM PATIENTS WITH A RARE PROGRESSIVE CENTRAL AND PERIPHERAL DEMYELINATING DISEASE.
Kristin Gellein1, Jon Skogholt2, Jan Aaseth3, Gunnar Børre Thoresen4, Syverin Lierhagen5, Tore Syversen1, Eiliv Steinnes1, and Trond Peder Flaten1.
1Norwegian University of Science and Technology (Trondheim, Norway); 2Municipality of Sør-Odal (Skarnes, Norway); 3Sykehuset Innlandet Kongsvinger (Kongsvinger, Norway); 4Sykehuset Innlandet Elverum (Elverum, Norway); 5Norwegian University og Science and Technology (Trondheim, Norway)
P-5 9.P05
PREFERENTIAL DYSFUNCTION IN THE HIPPOCAMPUS IN ZINC DEFICIENCY.
Fumika Kan, Haruna Tamano, Hiromasa Itoh, Atsushi Takeda, and Naoto Oku.
University of Zuoka (Zuoka, Japan)
P-6 9.P06
INCREASE IN DEPRESSION-LIKE BEHAVIOR OF YOUNG RATS DURING ZINC DEFICIENCY.
Mika Kawamura, Haruna Tamano, Hiromasa Itoh, Atsushi Takeda, and Naoto Oku.
University of Shizuoka (Shizuoka-shi, Japan)
P-7 9.P07
IMPACT OF DIETARY VITAMIN B12 AND FOLIC ACID DEFICIENCY AND ANEMIA ON SCHOOL PERFORMANCE OF BEDOUIN CHILDREN IN SOUTHERN ISRAEL.
Rafik Masalha1, and Zaid Afawi2.
1Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel. (Beer Sheva, Israel); 2Sourasky Medical Center, Tel-Aviv, Israel (Beer Sheva, Israel)
P-8 9.P08
THE DIFFERENT INFLUENCE OF SOME BIVALENT CATIONS ON MORPHINE-INDUCED PHYSICAL DEPENDENCE.
Mihai Nechifor, Dan Chelarescu, Diana Ciubotariu, and Mihaela Pascu.
Univ.Med. Pharm "Gr. T. Popa" Iasi (Iasi, Romania)
P-9 9.P09
PRION PROTEIN PROTECTS AGAINST ZINC-MEDIATED CYTOTOXICITY BY MODIFYING INTRACELLULAR EXCHANGEABLE ZINC COMPARTMENTATION IN CULTURED CELLS.
Walid Rachidi1, Fabrice Chimienti2, Michel Seve3, and Alain Favier1.
1CEA/UJF (Grenoble, France); 2Mellitech (Grenoble, France); 3UJF (Grenoble, France)
P-10 9.P10
ZN PROTECTS DERANGEMENT OF ALCOHOLIZED RAT BRAIN MACRO- AND TRACE ELEMENTS (TE) CONTENT.
Anatoly Skalny, and Elena Vyatchanina.
Institute of General Pathology and Pathophysiology RAMS (Moscow, Russian Federation)
P-11 9.P11
EFFECT OF SUBCHRONIC MANGANESE INTOXICATION ON BRAIN MORPHOLOGY AND MANGANESE LEVEL IN RAT PUPS.
Tamar Bikashvili1, Asmat Shukakidze2, Nino Chkhartishvili3, and Ilia Lazrishvili4.
1I.Beritashvili Institute of Physiology (Tbilisi, Georgia); 2Tbilisi Medical University (Tbilisi, Georgia); 3Kutaisi State University (Kutaisi, Georgia); 4I.Beritashvili Institute of Physiology (Tbilisi, Georgia)
P-12 9.P12
TRACE ELEMENTS IN CEREBROSPINAL FLUID OF PATIENTS AFFECTED BY NEURODEGENERATIVE DISEASES: AN OVERVIEW OF ANALYTICAL DATA.
Margherita Speziali1, and Michela Di Casa2.
1CNR (Pavia, Italy); 2Dip. Chimica Generale Università Pavia (Pavia, Italy)
P-13 9. P13
ASSOCIATION OF BODY IRON STORES WITH DEVELOPMENT AMONG PRESCHOOL CHILDREN.
Usha Dhingra1, Sunil Sazawal1, Archana Sarkar2, Saikat Deb1, Pratibha Dhingra2, Venugopal P Menon2, and Robert E Black1.
1Johns Hopkins University (Baltimore, USA); 2Center for Micronutrient Research,Annamalai University (New Delhi, India)
P-14 9.P14
PROTECTIVE EFFECT OF SELENIUM ON CIPROFLOXACIN-INDUCED CONVULSIONS IN MICE.
Filiz Hincal1, and Tambay Taskin2.
1Hacettepe University (Ankara, Turkey); 2Actavis (Istanbul, Turkey)
P-15 9.P15
HEPATIC AND PRESYMPTOMATIC WILSON DISEASE PATIENTS RELAPSED WITH PSYCHIATRIC SYMPTOMS DUE TO POOR MEDICATION COMPLIANCE.
Misako Inoue1, Norikazu Shimizu1, Yoshinao Fujikawa1, Koichi Mizuguchi2, and Tsugutoshi Aoki1.
1Toho university (Tokyo, Japan); 2National Center for Child Medical Health and Development (Tokyo, Japan)
P-16 9.P16
TRACE ELEMENT FINGERPRINTS OF HUMAN DEPRESSION.
Berislav Momcilovic, Juraj Prejac, and Nikola Ivicic.
Institute for Medical Research and Occupational Health (IMI) (Zagreb, Croatia)
P-17 9.P17
ZINC INFLUENCE ON REWARD SYSTEM IN NAÏVE AND MORPHINE-TREATED RATS.
Diana Ciubotariu1, Mihaela Pascu2, and Mihai Nechifor2.
1University of Medicine and Pharmacy, Iasi, ROMANIA (Iasi, Romania); 2University of Medicine and Pharmacy (Iasi, Romania)
P-18 9.P18
ANTIOXIDANT ENZYME LEVELS AND LIPID PEROXIDATION IN SCHIZOPHRENIC PATIENTS AND THEIR NON-AFFECTED SIBLINGS.
Abdelhamid Kerkeni1, Leila Ben Othmane1, Chiraz Fendri1, Muriel Bost2, Guy Chazot2, Lotfi Gaha1, and Anwar Mechri1.
1Faculté de Medecine (Monastir, Tunisia); 2Institute for UNESCO (Lyon, France)
Category 11: Toxicity of Trace Elements
Chair: Michael Aschner
Co-Chair: Max Costa
P-19 11.P26 CESIUM TOXICITY ARISING FROM ANTICANCER THERAPY. Andre Mattman1, Daisy Baulcomb2, Mark Wylie2, Thomas Mock2, Robert Brown3, Wendy Gordon3, and Matthew Wiens4.
1Children's & Women's Health Centre of British Columbia (Vancouver, Canada); 2Children’s & Women’s Health Centre of British Columbia (Vancouver, Canada); 3Royal Columbian Hospital (New Westminster, Canada); 4University of British Columbia (Vancouver, Canada)
P-20 11.P01
THE CELLULAR EFFECTS INDUCED BY PB2+ AND ZN2+ ACTION ON HUMAN ERYTHROCYTES AND LYMPHOCYTES.
Igor Volotovski, and Ekaterina Slobozanina.
Institute of Biopysics and Cell Engineering, Belarus Satellite Center of TEI for UNESCO (Minsk, Belarus)
P-21 11.P02 ZINC CONCENTRATION IN HUMAN AUTOPSY AND BODY FLUIDS.
Teresa Lech, and Jozefa Krystyna Sadlik.
Institute of Forensic Research (Krakow, Poland)
P-22 11.P03 ESTIMATION OF COMMON EFFECT OF ELEUTHEROCOCCUS SENTICOSUS (RUPR. ET MAXIM. EX MAXIM) EXTRACT AND CADMIUM ON MITOTIC AND APOPTOTIC ACTIVITY OF LIVER CELLS. Alina Smalinskiene1, Vaiva Lesauskaite1, Virgilijus Zitkevičius2, Nijole Savickiene2, Stanislovas Ryselis3, Oleg Abdrakhmanov3, Ilona Sadauskiene3, Leonid Ivanov3, and Arunas Savickas4. 1Institute of Cardiology Kaunas University of Medicine (Kaunas, Lithuania); 2Department of Pharmaceutical Chemistry and Pharmacognosy Kaunas University of Medicine (Kaunas, Lithuania); 3Institute of Biochemical Research, Kaunas University of Medicine (Kaunas, Lithuania); 4Department of Drug Technology and Pharmaceutical Management, Kaunas University of Medicine (Kaunas, Lithuania)
P-23 11.P04 COMPARISON OF EFFECTS OF ECHINACEA PURPUREA AND ELEUTHEROCOCCUS SENTICOSUS (RUPR. ET MAXIM. EX MAXIM) EXTRACTSON THE ACCUMULATION OF CADMIUM IN DIFFERENT ORGANS AN MITOTIC ACTIVITY OF LIVER CELLS.
Virgilijus Zitkevičius1, Nijole Savickiene1, Alina Smalinskiene2, Vaiva Lesauskaite2, Stanislovas Ryselis3, Oleg Abdrakhmanov3, Ilona Sadauskiene3, Leonid Ivanov3, and Arunas Savickas4. 1Department of Pharmaceutical Chemistry and Pharmacognosy Kaunas University of Medicine (Kaunas, Lithuania); 2Institute of Cardiology, Kaunas University of Medicine (Kaunas, Lithuania); 3Institute of Biochemical Research, Kaunas University of Medicine (Kaunas, Lithuania); 4Department of Drug Technology and Pharmaceutical Management, Kaunas University of Medicine (Kaunas, Lithuania)
P-24 11.P05 TOXIC METHYLATION OF DIMETHYLTIN TO TRIMETHYLTIN IN HUMAN.
Yoko Endo.
Japan Labour Health and Welfare Organization (Tokyo, Japan)
P-25 11.P06 STRATEGIES FOR SAFE AND EFFECTIVE THERAPEUTIC MEASURES AGAINST METALS : ROLE OF MICRONUTRIENTS.
Sangeeta Shukla.
Jiwaji University (Gwalior, India)
P-26 11.P07 GENE EXPRESSION ANALYSIS OF THE MOUSE BRAIN PERINATALLY EXPOSED TO METHYLMERCURY AND/OR POLYCHLORINATED BIPHENYLS.
Miyuki Shimada1, Satomi Kameo2, Norio Sugawara3, Satomi Murata-Mizukami4, Takashi Ohba2, Kunihiko Nakai2, Hitoshi Iwahashi4, and Hiroshi Satoh2. 1Tohoku University Graduate School of Medicine (Sendai, Japan); 2Environmental Health Sciences, Tohoku University Graduate School of Medicine (Sendai, Japan); 3 Department of Neuro-psychiatry, Hirosaki University (Hirosaki, Japan); 4Human Stress Signal Research Center, AIST (Ikeda, Japan)
P-27 11.P08 EFFECT OF NICKEL ON THE TESTICULAR AND EPIDIDYMAL STRUCTURE AND ITS DISTRIBUTION IN THE RAT ORGANISM AFTER AN EXPERIMENTAL ADMINISTRATION.
Robert Toman1, Lenka Babikova1, Jozef Golian1, Peter Massanyi1, Svatoslav Hluchy1, Norbert Lukac1, Robert Stawarz2, Grzegorz Formicki2, and Peter Cupka1.
1Slovak Agricultural University (Nitra, Slovakia); 2Pedagogical University of Krakow (Krakow, Poland)
P-28 11.P09 SPECIATION OF MERCURY IN THE TISSUES OF THE RATS WHICH RECEIVED DENTAL AMALGAM FILLINGS.
Yoshifumi Takahashi1, Shozo Tsuruta1, Akira Yasutake2, and Masumi Sawada2.
1Aichi-Gakuin University (Nagoya, Japan); 2National Institute for Minamata Disease (Minamata, Japan)
P-29 11.P10 HEALTH CONSEQUENCES OF EXPOSURE TO DIET SOURCED ENVIRONMENTAL CADMIUM IN CENTRAL JAMAICA.
Paul Wright, Gerald Lalor, Vaughn Rattray, and Richard Hanson.
International Centre for Environmental and Nuclear Sciences (ICENS) (St Andrew, Jamaica)
P-30 11.P11 SELENIUM AS AN ANTIOXIDANT IN THE THYROID GLAND.
Monireh Aghajany1, Saeid Kalantari2, and Abdolrasoul Sobhani2.
1Isfahan University Of Medical Sciences (Isfahan, Islamic Rep. of Iran); 2Guilan University of Medical Sciences (Rasht, Iran, Islamic Rep. of)
P-31 11.P12 MORPHOFUNCTION THE CONDITION OF THE LIVER AT LOADING ORGANISM TOXIC BY DOZES A CADMIUM AND LEAD ON THE BACKGROUND OF VARIOUS SECURITY OF THE DIET BY MINERAL SUBSTANCE.
Svyatoslav Lebedev1, Sergei Miroshnikov1, Anatolii Skalny1, Elena Barisheva1, Valentina Polyakova2, and Elena Sizova1.
1Orenburg State University (Orenburg, Russian Federation); 2Orenburg Medicine University (Orenburg, Russian Federation)
P-32 11.P13 DISTRIBUTION AND METABOLISM OF TELLURIUM IN RATS INGESTED WITH SODIUM TELLURITE.
Yasumitsu Ogra, Reina Kobayashi, Kazuya Ishiwata, and Kazuo T. Suzuki.
Chiba University (Chiba, Japan)
P-33 11.P14 ASSESSMENT OF EFFECT OF ELEUTHEROCOCCUS SENTICOSUS (RUPR. ET MAXIM. EX MAXIM) EXTRACT ON THE ACCUMULATION OF CADMIUM IN SPLEEN AND THE EXTENT OF MACROFAGUS AREA.
Nijole Savickiene1, Virgilijus Zitkevičius1, Alina Smalinskiene2, Vaiva Lesauskaite2, Stanislovas Ryselis3, Oleg Abdrakhmanov3, Ilona Sadauskiene3, Leonid Ivanov3, and Arunas Savickas4. 1Department of Pharmaceutical Chemistry and Pharmacognosy,Kaunas University of Medicine (Kaunas, Lithuania); 2Institute of Cardiology, Kaunas University of Medicine (Kaunas, Lithuania); 3Institute for Biomedical Research, Kaunas University of Medicine (Kaunas, Lithuania); 4Department of Drug Technology and Pharmaceutical Management, Kaunas University of Medicine (Kaunas, Lithuania)
P-34 11.P15 A WILSON DISEASE PATIENT WITH RECURRED ACUTE HEPATITIS DUE TO POOR MEDICAL COMPLIANCE.
Kaoru Hirai, Atsuko Watanabe, Norikazu Shimizu, and Tsugutoshi Aoki.
Toho University (Tokyo, Japan)
P-35 11.P16 EFFECT OF TRACE ELEMENTS IN A COMPLEX PREPARATE (IMMUNOVET-HBM™ TRADE NAME) ON THE ACTIVITY OF DIGESTIVE ENZYMES IN BROILER CHICKENS.
Kosa Emma, Jakab Laszlo, and Nagy Gyula. Szent Istvan. University Faculty Of Veterinary Science (Budapest, Hungary)
P-36 11.P17 AMELIORATIVE EFFECTS OF N-ACETYL CYSTEINE ALONG WITH THE COMBINATION OF ANTIOXIDANTS AGAINST CHRONIC EXPOSURE INDUCED BY METHYLMERCURY TOXICITY.
Deepmala Joshi, Sadhana Shrivastava, and Sangeeta Shukla.
Jiwaji University (Gwalior, India)
P-37 11.P18 EFFECTIVENESS OF COMBINATION THERAPY AGAINST SUBCHRONIC EXPOSURE OF ALUMINIUM.
Sadhana Shrivastava1, Varsha Singh1, Deepmala Joshi1, and Mohamed Abdulla2.
1Jiwaji University (Gwalior, India); 2Trace Element- Institute for UNESCO (Lyon, France)
P-38 11.P19 INVESTIGATION OF CYTOTOXIC EFFECTS OF THALLIUM ACETATE AND ELLAGIC ACID ON NIH 3T3 CELL LINE.
Filiz Alanyalı, Ahmet Ozata, and Oge Basoglan.
Anadolu University (Eskişehir, Turkey)
P-39 11.P20 SPECIATION ANALYSIS BY HPLC-ICP-MS OF ARSENIC IN URINE OF INDIVIDUALS DRINKING POLLUTED WATER IN BANGLADESH.
Ginji Endo1, Md. Ahsan Habib1, Akihisa Hata1, Yoshiaki Nakajima2, Michiko Matsuda2, Masanori Ogawa2, and Yoko Endo2.
1Osaka City University (Osaka, Japan); 2Japan Labour Health Organization (Tokyo, Japan)
P-40 11.P21 ROLE OF METALLOTHIONEINES IN THE MECHANISM OF HEAVY METALS TOXIC EFFECTS.
Leonid Shafran, Elena Pykhteeva, and Dmitry Bolshoy.
Ukrainian Scientific and Research Institute of Medicine on Transport (Odessa, Ukraine)
P-41 11.P22 SMALL DOSES OF MERCURY EXPOSURE: WHAT DOES IT MEAN?
Dmitry Bolshoy, Elena Pykhteeva, Leonid Shafran, and Elena Tretiakova.
Ukrainian Scientific and Research Institute of Transport Medicine (Odessa, Ukraine)
P-42 11.P23 HYGIENE AND TOXICOLOGY OF ZN- AND PB-CONTAINING SHIP PAINTS.
Diana Timoshina1, Alexandr Tretiakov1, Olga Kapustinskaya1, and Galina Burlak2.
1Ukrainian Scientific and Research Institute of Transport Medicine (Odessa, Ukraine); 2Ministry of Public Health of Ukraine (Kiev, Ukraine)
P-43 11.P24 NEW ASPECTS OF METALLONEPHROTOXICOSES PATHOGENESIS.
Anatoly Gozhenko, and Leonid Shafran.
Ukrainian Scientific and Research Institute of Transport Medicine (Odessa, Ukraine)
P-43 11.P27 MATERNAL-TO-FETAL CADMIUM TRANSFER AND ITS EFFECTS ON TRACE ELEMENT REGULATION IN THE REPRODUCTIVE ORGANS OF FEMALE RATS.
Hisayoshi Ohta1, Yasuhiro Nakamura1, Yohei Ohkawa1, Yoshifumi Ohmori1, and Keiji Suzuki2.
1Kitasato University (Sagamihara, Kanagawa, Japan); 2Gunma University (Maebashi, Japan)
P-44 11.P25 CADMIUM IN URINE AND KIDNEY BIOMARKERS IN SWEDISH WOMEN.
Gerd Sällsten.
Sahlgrenska Academy and University Hospital (Göteborg, Sweden)
Category 12: Trace Element Detection and Quantification
Chair: Enrico Sabbioni
Co-Chair: Maria Luisa de Carvalho
Co-Chair: Edouard Jallot
P-45 12.P01 DETERMINATION OF SERUM/PLASMA CERULOPLASMIN AND FREE-COPPER BY HPLC/INDUCTIVELY COUPLED PLASMA-MASS SPECTROMETRY FOR THE DIAGNOSIS OF WILSON DISEASE.
Kenji Kobayashi1, Rizky Abdulah1, Yoko Katsuya1, Chie Fujisawa2, Takeaki Nagamine3, Tomoko Suzuki4, Takashi Ishige4, Akihiro Morikawa4, Masami Murakami5, Norikazu Shimizu6, Hiroko Kodama2, and Hiroshi Koyama1. 1Department of Public Health, Gunma University Graduate School of Medicine (Mebashi, Japan); 2Department of Pediatrics, Teikyo University School of Medicine (Tokyo, Japan); 3School of Health Science, Gunma University (Maebashi, Japan); 4Department of Pediatrics & Developmental Medicine, Gunma University Graduate School of Medicine (Maebashi, Japan); 5Department of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine (Maebashi, Japan); 6The second Department of Pediatrics, Toho University School of Medicine (Tokyo, Japan)
P-46 12.P02 DETERMINATION OF LEAD AND CADMIUM IN VARIOUS FOOD SAMPLES BY GRAPHITE FURNACE ATOMIC ABSORPTION SPECTROMETRY AFTER SEPARATION BY USING THE COPRECIPITATION METHOD.
Tülay Oymak1, Şerife Tokalioğlu2, Vedat Yilmaz2, Şenol Kartal2, and Didem Aydin2.
1Gazi University (Ankara, Turkey); 2Erciyes University (Kayseri, Turkey)
P-47 12.P03 DEVELOPMENT OF AN ANALYTICAL METHOD FOR THE DETERMINATION OF CADMIUM AND LEAD IN OFFAL BY Z-ETA-AAS.
Sepe Alessandra, Giordano Rosa, D'ilio Sonia, Colabucci Andrea, Ciprotti Maria, Di Gregorio Marco, and Costantini Sergio. Istituto Superiore di sanità (Rome, Italy)
P-48 12.P04 SYNTHESIS AND APPLICATION OF A NEW CHELATING RESIN FUNCTIONALIZED WITH SALICYLALDOXIME FOR THE DETERMINATION OF PB(II), NI(II), CU(II) AND MN(II) IONS IN WATER SAMPLES BY FLAME ATOMIC ABSORPTION SPECTROMETRY.
Şerife Tokalioğlu, and Şenol Kartal.
Erciyes University (Kayseri, Turkey)
P-49 12.P05 EFFECTS OF FORMALIN FIXATION ON TRACE ELEMENT CONCENTRATIONS IN BIOLOGICAL TISSUE. Kristin Gellein1, Trond Peder Flaten1, Ketih Erikson2, Michael Aschner3, and Tore Syversen1.
1Norwegian University of Science and Technology (Trondheim, Norway); 2Univeristy of North Carolina Grensboro (Grensboro, USA); 3Vanderbilt University Medical Center (Nashville, USA)
P-50 12.P06 THE CRL-ISS PROFICIENCY TESTS ON TRACE ELEMENTS IN MEAT AND MILK: ORGANIZATION AND RESULTS.
Ciaralli Laura, Senofonte Oreste, Giordano Rosa, Violante Nicola, Sepe Alessandra, D'Amato Marilena, Colabucci Andrea, and Costantini Sergio. Istituto Superiore di Sanità (Rome, Italy)
P-51 12.P07 DRINKING WATER: AN ESSENTIAL CONDITION FOR THE HUMAN EXISTENCE.
Cical Elena Gabriela1, Mecea Mircea1, Gasparik Geza1, and Burtica Georgeta3.
1Sc Vital Sa (Baia Mare, Romania); 2University “Politehnica” Timisoara (Timisoara, Romania)
P-52 12.P08 IODINE SPECIATION IN THYROID GLAND BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY COUPLED WITH INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY.
Nereida Carrion1, José Zabala1, Miguel Murillo1, Nelly Seijas2, and Leopoldo Duarte3. 1Universidad Central de Venezuela (Caracas, Venezuela); 2Morgue Forense (Caracas, Venezuela); 3Hospital Vargas de Caracas (Caracas, Venezuela)
P-53 12.P09 FIELD-BASED ARSENIC SPECIATION IN ARGENTINEAN WATER SAMPLES: LINK TO ARSENIC POISONING.
Jenny O'Reilly1, Michael Watts2, and Neil Ward1.
1University of Surrey (Guildford, United Kingdom); 2British Geological Survey (Nottingham, United Kingdom)
P-54 12.P10 MULTIVARIATE DATA VISUALIZATION METHODS BASED ON ELEMENTAL ANALYSIS OF HERBAL DRUGS BY ICP-MS.
Biljana Marosanovic1, Vesna Kilibarda 2 , and Slavica Razic3.
1SP Laboratorija (Becej, Serbia); 2Military Medical Academy, Poison Control Centre, Department of toxicological chemistry (Belgrade, Serbia); 3Faculty of Pharmacy, Institute of Analytical Chemistry, University of Belgrade (Belgrade, Serbia)
P-55 12.P11 METHYL MERCURY IN BIOLOGICAL FLUIDS BY ISOTOPE DILUTION.
Douglas Baxter, Ilia Rodushkin, and Ingemar Berglund;
ALS Scandinavia (Luleå, Sweden)
P-56 12.P12 ENVIRONMENTAL AND HEALTH CONSEQUENCES OF MERCURY AIR POLLUTION.
Zdravko Spiric1, Marina Frontasyeva2, Trajce Stafilov3, Vangelica Enimiteva4, Dragan Bukovec5, and Zrinka Mesic1;
1Oikon Ltd. - Institute for Applied Ecology (Zagreb, Croatia); 2Frank Laboratory of Neutron Physics, Joint Institute for Nuclear Research (Dubna, Russian Federation); 3Institute of Chemistry Faculty of Science St. Cyril and Methodius University (Skopje, Macedonia); 4Institute of Chemistry Faculty of Science St. Cyril and Methodius University (Skopje, Macedonia); 5Croatian Natural History Museum Zagreb (Zagreb, Croatia)
P-57 12.P13 PRE-ANALYTICAL FACTORS CAN CAUSE INTERMITTENT RAISED URINE CADMIUM RESULTS.
Susan Grant, Trevor Walmsley, Ngaire Smidt, Chris Florkowski, and Peter George. Canterbury Health Laboratories (Christchurch, New Zealand)
P-58 12.P14 NOVEL DEVICE FOR DIRECT MEASUREMENT OF NON-CERULOPLASMIN COPPER IN WILSON’S DISEASE.
John Althaus, Kyong-Hoon Lee, Charles Bisgaier, and Steve Kanzer. Pipex Pharmaceuticals (Ann Arbor, USA)
P-59 11.P28 TETRATHIOMOLYBDATE FOR WILSON’S DISEASE INHIBITS COPPER-DEPENDENT LIPID PEROXIDATION.
John Althaus1, Christian Althaus1, Charles Bisgaier1, Steve Kanzer1, and George Brewer2. 1Pipex Pharmaceuticals (Ann Arbor, USA); 2University of Michigan (Ann Arbor, USA)
14:30-17:30 Four Concurrent Sessions (Symposia F and G; Minisymposium #6, #7, and #8)
Symposium F--MINOS
Symposium: Mineral Elements and Molecular Signaling as it Relates to Human Disease
(ISTERH/NTES/HTES '07 acknowledges the generous support from AKZO NOBEL FUNCTIONAL CHEMICALS and ELSEVIER)
Chair: Bernhard Hennig
Co-Chair: Emily Ho
Purpose of Session: The many new findings to be presented will help to understand the nutritional needs for proper vascular functions, and especially the involvement of micronutrients like zinc, selenium and copper on cellular antioxidant defense as it relates to the pathology of vascular diseases. Zinc deficiency can induce oxidative stress, increased the DNA binding activity of NF-B and AP-1, and increase endothelial production of IL-6. Low zinc levels may also compromise DNA integrity and increase cancer risk, probably through modulation of oxidative-stress sensitive cell signaling. Similar to zinc, oxidative stress in tumor progression also can be controlled by selenium. Preincubation of fibroblasts with selenite, selenoprotein P or other antioxidants can lower lipid peroxidation and subsequent inhibition of expression of biomarkers for myofibroblastic cells. Selenium and other trace elements may contribute to anti-invasive and anti-metastatic strategies. Selenium also is an important micronutrient in the regulation of immune function and viral pathogenesis. Finally, copper transporters and chaperones may provide critical regulatory roles in copper trafficking and cellular copper signaling associated with antioxidant enzymes such as Cu/Zn superoxide dismutase. Thus, these findings will provide practical implications of high importance for public health.
14:30
"Role of zinc in endothelial cell function: implications in atherosclerosis”, Bernhard Hennig
15:00
"Oxidative stress in tumor progression: intervention by selenium”, Peter Brenneisen
15:30
"Influence of zinc on oxidative stress, DNA integrity and cancer risk”, Emily Ho
16:00 Delegate Coffee Break (OLYMPUS)
16:30
"Maintaining copper balance: roles of copper transporters and chaperones”, Jesse Bertinato
Symposium G--ATHENA-ARTEMIS
Symposium: Is copper involved in carcinogenesis/ carcinostatics?
(ISTERH/NTES/HTES '07 acknowledges the generous support from TEIKYO UNIVERSITY )
Chair: Hiroko Kodama
Co-Chair: Norikazu Shimizu
Purpose of Session: This symposium summarizes new information on the involvement of copper in carcinogenesis/carcinostatics. The Long-Evans cinnamon (LEC) rat, an animal model of Wilson’s disease, suffers from hepatocellular carcinoma in a very high frequency. Hepatocellular carcinoma has also been reported in patients with Wilson disease who could survive for a long period by treatments with Wilson’s disease. It has also been reported that copper accumulates in cancer cells of the patients with hepatocellular carcinoma who are not the patients with Wilson’s disease. ATP7B, the responsible copper-transporter for Wilson’s disease, has recently been reported to be expressed in various kinds of malignant cells and to influence the effect of anticancer medicines.
14:30 "Possible association of Wilson’s disease with hepatocellular carcinoma”, Yan-Hong Gu
15:00
"Carcinogenesis in LEC rat and patients with Wilson disease”, Norikazu Shimizu
15:30
"The effects of Copper on Carcinoma Development and Angiogenesis”, Masaaki Ebara
16:00 Delegate Coffee Break (OLYMPUS)
16:30
"Copper transporters regulate the cellular pharmacology of cisplatin”, Stephen Howell
Minisymposium #7--EUROPA-DANAE
Chair: Atsushi Takeda
Co-Chair: Andrzej Szutowicz
Category 9: Neurological Diseases & Neuropsychological Impairment
14:30 9.S01
UNIQUE RESPONSE OF EXTRACELLUAR ZINC IN THE VENTRAL HIPPOCAMPUS AGAINST NOVELTY STRESS.
Shingo Kanno, Naomi Sakurada, Akira Minami, Atsushi Takeda, and Naoto Oku.
University of Shizuoka (Shizuoka, Japan)
14:45 9.S02
METAL EXPOSURE IN NEURODEGENERATIVE DISORDERS.
Per M Roos, and Monica Nordberg.
Karolinska Institutet (Stockholm, Sweden)
15:00 9.S03
INVOLVEMENT OF ZINC IN SYNAPTIC PLASTICITY AND NEURODEGENERATION IN THE HIPPOCAMPUS VIA CROSSTALK WITH CALCIUM.
Atsushi Takeda, Sayuri Fuke, Naomi Sakurada, Akira Minami, and Naoto Oku.
University of Shizuoka (Shizuoka, Japan)
15:15 9.S04
BIOMARKERS IN CEREBROSPINAL FLUID IN ALZHEIMER’S DISEASE AND NORMAL COGNITION.
Monica Nordberg1, Nina Johansson2, Hans Basun3, Kaj Blennow4, and Maria Eriksdotter-Jönhagen5.
1Karolinska Institutet ( SE-17177 Stockholm, Sweden); 2Department NVS, Section of Clinical Geriatrics, Karolinska Institute and Karolinska University Hospital, Huddinge SE-141 86 Stockholm, Sweden Institute Environmental Medicine, Karolinska Institute (Stockholm, Sweden); 3AstraZeneca, Clinical Science, R&D Södertälje, SE-151 85 and Department of Public Health / Geriatrics, Uppsala University Hospital, SE-751 25 (Södertälje, Uppsala, Sweden); 4Department of Clinical Neuroscience, Section of Experimental Neuroscience, The Sahlgrenska Academy at Gothenburg University, SE-43180 (Gothenburg, Sweden); 5Department NVS, Section of Clinical Geriatrics, Karolinska Institute and Karolinska University Hospital, Huddinge SE-141 86 (Stockholm, Sweden)
15:30 9.S05
ENHANCEMENT OF AGGRESSIVE BEHAVIOR OF YOUNG MICE INDUCED WITH SOCIAL ISOLATION IN ZINC DEFICIENCY.
Haruna Tamano, Kan Fumika, Atsushi Takeda, and Naoto Oku.
University of Shizuoka (Shizuoka, Japan)
15:45 9.S06
EFFECTS OF A SE RESTRICTED-DIET ON BRAIN ANTIOXIDANT STATUS AND BRAIN FUNCTION IN AGED RATS.
Isabelle Hininger-Favier1, Frederic Canini2, Farida Belem3, Mireille Osman3, Veronique Ducros4, and Anne-Marie Roussel5.
1LBFA (NVM) (Grenoble, France); 2CRSSA (La Tronche, France); 3INSERM U844-UJF Grenoble (Grenoble, France); 4DBI-CHU Grenoble (Grenoble, France); 5INSER U844-UJF Grenoble (Grenoble, France)
16:00 Delegate Coffee Break (OLYMPUS)
16:30 9.S07
DISTURBANCES IN ACETYL-COA METABOLISM AND CYTOTOXIC EFFECTS OF ZINC IN SN56 CHOLINERGIC NEUROBLASTOMA CELLS.
Andrzej Szutowicz, Anna Ronowska, Agnieszka Jankowska-Kulawy, and Hanna Bielarczyk.
Medical University of Gdansk, Department of Laboratory Medicine (Gdansk, Poland)
Category 5: Disorders of Aging
16:45 5.S01
SERUM SELENIUM, COPPER AND ZINC IN ELDERLY POPULATION FROM COASTAL AND CONTINENTAL AREAS OF CROATIA.
Jasna Jurasovic, Mladen Pavlovic, Alica Pizent, and Naima Corovic.
Institute for Medical Research and Occupational Health (Zagreb, Croatia)
17:00 5.S02
STUDIES ON MOLECULAR MECHANISMS IN UNDERSTANDING COPPER INDUCED AMYLOID BETA AGGREGATION AND ITS RELEVANCE TO ALZHEIMER’S DISEASE.
Veer Bala Gupta1, Indi SS 2, and KSJ Rao1.
1Central Food Technological Research Institute (Mysore, India); 2Indian Institute of Science (Bangalore, India)
Minisymposium #8--LEDA
Chair: Sunil Sazawal
Co-Chair: Nicholas Ralston
Category 11: Toxicity of Trace Elements
14:30 11.S01
IMMUNOLOCALIZATION OF METALLOTHIONEINS IN LIVER AND KIDNEY OF WISTAR RATS EXPOSED TO CADMIUM.
Yihuai Liang1, Huiqi Li1, Lijian Lei1, Taiyi Jin1,3, Monica Nordberg2, and Gunnar Nordberg3.
1Department of Occupational Health, School of Public Health, Fudan University (Shanghai, China); 2Institute of Environmental Medicine, Karolinska Institutet (Stockholm, Sweden); 3Environmental Medicine, Department of Public Health and Clinical Medicine, Umea University (Umea, Sweden)
14:45 11.S02
ROLE OF SELENIUM IN SEAFOOD RISK:BENEFIT EVALUATIONS.
Nicholas Ralston1, and John Kaneko2.
1University of North Dakota (Grand Forks, USA); 2PACMAR (Honolulu, USA)
15:00 11.S03
ZINC PROTOPORPHYRIN IS A STRONG PREDICTOR OF LEAD LEVELS IN DEVELOPING COUNTRY SETTINGS WHERE LEAD LEVELS ARE HIGH.
Sunil Sazawal1, Usha Dhingra1, Saikat Deb1, Pratibha Dhingra2, Archana Sarkar2, Venugopal P Menon2, and Robert E Black1.
1Johns Hopkins University (Baltimore, USA); 2Center for Micronutrient Research,Annamalai University (New Delhi, India)
15:15 11.S04
CADMIUM REDUCES BETA-CASEIN GENE EXPRESSION IN SECRETING MURINE MAMMARY EPITHELIAL CELLS.
Helena Öhrvik, Maria Nyström, Agneta Oskarsson, and Jonas Tallkvist.
Swedish University of Agricultural Sciences (Uppsala, Sweden)
15:30 11.S05
BROMIDE INTERFERENCE WITH IODINE METABOLISM IN THE RAT.
Stanislav Pavelka.
Institute of Physiology, Czech Acad. Sci., Prague, and Faculty of Science, Masaryk University, Brno, Czech Republic (Prague 4, Czech Republic)
15:45 11.S06
TRACE ELEMENT STATUS OF MILITARY PERSONNEL AFTER PRT.
Rima Naginiene1 , Ramute Vaicaitiene2, Dale Baranauskiene1, Jolanta Gurauskiene2, Jadvyga Milieskiene2, Stasys Ryselis1, and Olegas Abdrachmanovas1.
1Institute for Biomedical Research, Kaunas University of Medicine (Kaunas, Lithuania); 2Military Medical Service of Lithuanian Armed Forces (Kaunas, Lithuania)
16:15 Delegate Coffee Break (OLYMPUS)
16:30 11.S07
INDUCTION OF METALLOTHIONEIN MRNA IN THE CEREBRUM AND CEREBELLUM AFTER A LOW DOSE OF THYMEROSAL INJECTION.
Takeshi Minami
Kinki University, School of Science & Engineering (Higashi-osaka, Japan)
16:45 11.S08
SOD GENE EXPRESSION AND ACTIVITIES IN KIDNEY FROM RATS EXPOSED TO CADMIUM. Xiang Cuiqin1, Mei Bing2, and Wu Zirong3.
1Shanghai Center for Diseas Control & Prevention (Shanghai, China); 2East China Normal University (Shanghai, China); 3East China Normal University (Shanghai, China)
Minisymposium #9--APHRODITE
Chair: Harold H. Sandstead
Co-Chair: Ananda Prasad
The Role of Micronutrients (Iodine, Iron and Zinc) in Intellectual Development
UNESCO / Trace Element - Institute for UNESCO Symposium
14:30 "Iodine and intellectual development : the role of ICCIDD in eliminating iodine deficiency disorders”, Michael B. Zimmermann
14:55
"Zinc and cognitive performance”, Harold H. Sandstead
15:20
"The role of micronutrients (iodine, iron and zinc) in intellectual
development: WHO's position”, Bruno de Benoist
15:45
"Ensuring Adequate Trace Mineral Intakes for Optimal Human
Development - Moving from Knowledge to Action”, MG Venkatesh Mannar
16:10 Delegate Coffee Break (OLYMPUS)
16:30 Discussion
18:00 Thursday posters removed from boards in OLYMPUS
18:00 Commercial exhibits dismantled
20:00 CRETA MARIS CONFERENCE CENTER, LEVEL 1
Reception and Banquet
___________________________________________________
FRIDAY MORNING, October 26
9:30-10:30 MINOS
Symposium H: Zinc and the Common Cold
(ISTERH/NTES/HTES '07 acknowledges the generous support from the GEORGE AND PATSY EBY FOUNDATION )
Chair: Monica Nordberg
Purpose of Session: Interest in the efficacy of zinc as a therapeutic treatment for the common cold has declined due to a series of negative trials. However, new research suggests that the chemical speciation by pH, dose response, type of salt and stability and chemistry of the carrier may explain variations in response. A proposed mechanism of action is discussed, the inhibition of intracellular adhesion molecule ICAM-1. ICAM1 (CD54) is expressed on cells of the immune system and is a binding receptor for Rhinovirus, the agent responsible for most respiratory viral infections. This provocative symposium by a world renowned zinc expert most likely will generate significant discussion.
9:30
"Zinc and the common cold: aspects of solution chemistry”, George Eby
10:00
"Treatment of the common cold with zinc: effect on pro-inflammatory cytokine (soluble interleukin-1 receptor antagonist) and ICAM-1”, Ananda Prasad
10:30 Closing Ceremony (MINOS)
Sophie Ermidou-Pollet, President, HTES
Ole Andersen, Representative, NTES
Curtiss D. Hunt, President, ISTERH
10:45-11:45 MINOS
International Society for Trace Element Research in Humans (ISTERH) Business Meeting
Open to all Conference delegates; only ISTERH Members vote
1. Approval of Agenda
2. President’s Report (C. Hunt, USA)
3. Secretary’s Report (H. Kodama, Japan)
a. Approval of Minutes of ISTERH Business Meeting held Nov 12, 2004 Bangkok, Thailand
4. Treasurer’s Report (Acting: C. Hunt, USA)
5. Report of Crete Meeting (D. Klimis-Zacas, C. Hunt)
6. Report of Awards Committee
Raulin Award: G. Brewer, Chair
Student Travel Awards: O. Andersen, Chair
7. Business Items
8. Report on the Journal of Trace Elements in Experimental Medicine (C. Hunt, USA)
9. Report of the Nominating Committee (Harold Sandstead, Chair, USA)
10. Election of Officers
11 Remarks of the incoming President
12. Other Business
Closing of Conference
12:30PM Adjournment
DISCLAIMERS & RESTRICTIONS
ISTERH/NTES/HTES '07 or ISTERH will not assume responsibility for medical expenses of conference participants and their guests at the conference. All participants are urged to ensure that they and their guests are covered by their own travel and health insurance policies while traveling to/from and while attending the conference.
ISTERH/NTES/HTES '07 or ISTERH is not responsible for private possessions lost or stolen at the conference.
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