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*Herbs*

Common Herbs
Generalized Herbal Discussion
Disclosure


Common Herbs

Cat’s Claw: Cat’s Claw (uncaria tomentosa) supports enhanced immune system function by augmenting white blood cell activity. Cat’s Claw is a large vine that derives its name from hook-like thorns that grow along the vine and resemble the claw of a cat. Cat’s Claw is grown in the highlands of the Peruvian Rainforest. This herb is indigenous to the Amazon rainforest. It has wide use among the indigenous tribes of this area. The inner bark is harvested in an ecologically sound manner so the plant is not destroyed. This herb has been used traditionally for intestinal health and to fight viral infections. Cat’s Claw is most noted for its immune enhancing properties but constituents of the plant have also demonstrated anti-inflammatory and anti-oxidant properties.
Available from: www.PowerHealth.org
Cat's Claw Supportive Information

Echinacea: Echinacea can "kick-start" exhausted immune systems that are sluggish and under-reactive for fighting infections. Echinacea has shown to enhance the immune system by supporting and activating thymus gland activity for action against virus infections. It has shown to sweep dead cells and other debris through the channels of the lymphatic system, and dispatches white blood cells to fight infection. It maximizes the power of the lymph nodes to filter broken-down material within the body. The production of lymphocytes and macrophages is escalated when Echinacea is added to the system. Echinacea is best used only when needed for assistance in fighting cold viruses, flu viruses, and other infections where immune system support is needed. If used on a regular basis the body will become too used to echinacea and therefore some of Echinacea’s effectiveness will be lost during the times when it is needed the most. Both Native Americans as well as early conventional practitioners have used this herb in the 19th century for disorders ranging from venomous bites and syphilis to the common cold. In fact, the American Indians used echinacea against more illnesses than any other plant. Today, Echinacea enjoys wide use, as an immune stimulant maximizing the power of the individuals’ own immune system immune system.
Available from: www.PowerHealth.org
Echinacea Supportive Information

Golden Seal Root: (Hydrastis Canadensis) This herb has a long history of use as an antibiotic and anti-microbial, and has enjoyed recent popularity as an adjunct to Echinacea for support during colds and flu. Goldenseal is a widely used and recommended antiseptic. Native Americans traditionally used goldenseal for digestive, respiratory and urinary disorders. It was also used topically by these cultures for skin and eye infections. It is most commonly used today for its anti-bacterial effects. The root is the potent, medically effective part of the plant. (The leaves are less potent.)
Available from: www.PowerHealth.org
Golden Seal Supportive Information

Kava Kalm: Kava Kava (Piper Methysticum) is an herb that has been used in the Fiji Islands for many years. There it is cultivated in large quantities, and the islanders use it as a social beverage, much like how we would use either coffee or alcohol. The effects of Kava Kava are a relaxation of mental stress while at the same time an enhancement of mental capacities. Kava Kava also helps to relax striated muscles. Striated muscles are the muscles that can be voluntarily moved such as arm and leg muscles groups, or neck muscles. Kava Kava does NOT affect smooth muscle such as the heart muscle or diaphragm muscle used for breathing. It is proposed that the reason Kava Kava enhances mental capacities is because relaxation of stressful situations coupled with relaxation of tense or spastic muscles such as the neck muscles, allows more blood flow to the brain. Additionally, by putting some of the stressful affects aside, anyone can think clearer. The ingredients in this Kava Kalm product are a blend of other nutritional factors that provides synergistic value to the overall calming effect. All ingredients are natural and safe. Kava Kalm does not contain St. John’s Wart herb.
Available from: www.PowerHealth.org
Kava Kava Supportive Information

Sleep: The ingredients in "Sleep" helps to assist naturally with occasional insomnia, restlessness, and night-time anxiety. "Sleep" contains Valerian Root, an herb that is used extensively in Alternative Care Medicine to provide sedative and relaxation effects, as well as sleep promoting benefits for many patients. Another ingredient in "Sleep" is Passionflower. Passionflower, which is more widely used in Europe than America, may help combat Parkinson’s disease. (Reference: The Herbal Handbook, by David Hoffmann.) Many other herbalists also agree that Passionflower may help combat Parkinson’s disease. Passionflower contains two reportedly effective anti-Parkinson’s compounds, harmine and harmaline alkaloids. (Reference: The Green Pharmacy by James A. Duke, Ph.D., 1997, p. 353.) The usage of Passionflower in a sleep remedy is due to its anti-anxiety and sedative effects. The other ingredients in "Sleep," Lemon Balm and Skullcap, are traditional herbs for calming the nervous system. A good night’s sleep allows Alpha Brains Waves to become active, which is important for quality rest. Alpha brain waves are most active during the phase of sleep known as "Rapid Eye Movement (REM) or more commonly referred to as "Deep Sleep."
Available from: www.PowerHealth.org

Garlic: (Allium Sativum) Garlic is a powerful healing herb, is was used to treat infected wounds and amebic dysentery during World War I. Garlic not only has been utilized as a medicinal herb within a number of cultures throughout history but also enjoys wide use today based upon good scientific research. Garlic has demonstrated anti-bacterial, anti-fungal, anti-viral and anti-parasitic properties. This herb provides excellent cardiovascular support through its beneficial effects on cholesterol, triglycerides and lowering blood “stickiness” (platelet aggregation). Garlic provides all the benefits of whole garlic without the pungency.
Available from: Alternative Care Doctor’s Offices (Naturopathic Doctors),
and many top quality health food stores.
Garlic Supportive Information

Ginkgo Biloba: The mechanism of Ginkgo is an increase in blood flow through "micro capillaries." Micro capillaries are the very tiny blood vessels the supply oxygen and nutrition to the more delicate organs of the body, such as the brain. Without proper oxygen and nutritional to the delicate organs of the body, degeneration occurs. Dementia in the elderly is often a result of insufficient blood and oxygen flow to the brain. Also associated with these deficiencies are short-term memory loss, vertigo, headache, ringing in the ears, lack of vigilance, and depression. Much of this is due to the presence of atherosclerotic cardiovascular disease. Because of the mechanism of Ginkgo, ginkgo can offer great hope. Ginkgo has also been shown to normalize acetylcholine receptors in the brain of aged animals and to also increase transmission of nerve impulses. Both of these factors are associated with Alzheimer’s disease. Shop carefully for the best available quality and potency of ginkgo, as this will make a big difference in effectiveness.
Available from: Alternative Care Doctor’s Offices (Naturopathic Doctors),
and many top quality health food stores.
Gingko Biloba Supportive Information

Valerian Root: (Valerian officinalis) This herb has a long history dating back to the Greeks. It has been used for centuries for its ability to provide a sedative and relaxant effect in individuals. It is commonly used today for nervousness, stress and its sleep promoting benefits. Valerian extract has been shown to reduce sleep latency significantly and improve sleep quality. It appears to be as effective as small doses of benzodiazepens and barbiturates with one difference: benzodiazepens and barbiturates increase morning sleepiness while valerian actually reduces morning sleepiness. Valerian should be widely available in health food stores. Be careful to buy quality and potent product, otherwise it will not work as effectively.
Available from: Many health food stores,
and most Alternative Health Care Doctor’s Offices
Valerian Root Supportive Information

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Generalized Herbal Discussion

herbs, herb, herbal medicine, herbology, cat’s claw, uncaria, echinacea, gingko, gingko biloba, golden seal root, goldenseal, hydrastis canadensis, kava kava, piper methysticum, garlic, allium sativum, valerian root, valerian. valerian officinalis Herbal Medicine can be a very powerful source of healing. However there are many sources of herbs that lack the proper potency needed for healing. Without the proper potency, or strength, herbs will have little effect.

There exists today amongst various disciplines of medicine, a lot of controversy surrounding the use of herbs medicinally. It has been my experience that some of this controversy could be seen in plainer light if all the herbs in question had their full potency potential.

It is very important when choosing herbs for purchase, that very careful attention be given to finding the most reliable source of quality herbal products.

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Cat's Claw Supportive Information

Oxyindole alkaloids appear to provide the immune system stimulation properties of this herb. Glycosides may be responsible for the anti-inflammatory and antioxidant actions of the plant.

It should be noted that there are no current studies (as far as we are aware) in humans. There do exist, though, a number of animal and test tube studies that confirm the immune stimulating benefits of this herb. Large anecdotal experiences in South America also attest to its immune stimulating properties. Also, lab research has demonstrated anti-inflammatory powers as well as vasodilating and platelet aggregation inhibition all of which may exert potential benefit for cardiovascular disease.

Cat’s Claw is popular in South American folk medicine for intestinal complaints, gastric ulcers, arthritis and to promote wound healing. Cat’s Claw has gained increasing popularity in North America for its immune stimulating properties and its potential benefit in supporting the cardiovascular system.

Side Effects:

No serious side effects have been reported with Cat’s Claw. Some experts believe this herb is contraindicated in autoimmune disease.

References:

1. Foster S. Herbs for Your Health. Loveland, CO: Interweave Press, 1996, 18–19.
2. Keplinger H. Oxyindole alkaloids having properties stimulating the immunologic system and preparation containing same. US Patent no. 5,302,611, April 12, 1994.
3. Aquino R, De Feo V, De Simone F, et al. Plant metabolites, new compounds and antiinflammatory activity of Uncaria tomentosa. J Nat Prod 1991; 54:453–59.
4. Foster S. Herbs for Your Health. Loveland, CO: Interweave Press, 1996, 18–19.

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Echinacea Supportive Information

Echinacea’s effectiveness is due to several constituents including polysaccharides, alkylamides and caffeic acid derivatives. These phytochemicals act to increase the production and activity of lymphocytes and macrophages and natural killer cells (the white blood cells). Additionally, Echinacea also increases the production of interferon. This important biologic response modifier assists in the control of viral infections.

A recent review study has assessed the effects of Echinacea in the treatment of the common cold. This review study performed by Bruce Barrett MD, PhD at the University of Wisconsin reevaluated 13 clinical trials held between 1980 and 1999 comprising a total of 2368 subjects. These were all double blind placebo controlled studies (consistent with drug study protocols in the US). When compared to patients on a placebo (sugar pill), those taking Echinacea developed fewer major colds, reported milder symptoms or had colds that ended earlier than the average untreated cold. Based on the evidence, it was Barrett’s opinion that Echinacea may be helpful in treating the severity and duration of a cold when taken early in the course of the infection. According to the author, these studies showed that Echinacea is more effective for acute treatment of colds than for long term prevention. In fact, while additional research has confirmed Echinacea’s benefit for acute cold and flu symptoms (once the infection has begun), other studies have called into question the effectiveness of long term Echinacea use for prevention of cold and flu.

Side Effects:

When used in recommended amounts, Echinacea has no toxic side effects. Individuals with a history of allergy to the daisy flower family should check with their health care provider prior to use. Some authorities suggest that Echinacea should not be used in individuals with autoimmune illness.

References:

1. Leuttig B, Steinmuller C, et al. Macrophage activation by the polysaccharide arabinogalactan isolated from plant cell cultures of Echinacea purpurea. J Natl Cancer Inst 1989;81:669–75.
2. Melchart D, Linde K, et al. Immunomodulation with Echinacea—a systematic review of controlled clinical trials. Phytomed 1994;1:245–54.
3. Dorn M, Knick E, Lewith G. Placebo-controlled, double-blind study of Echinacea pallida redix in upper respiratory tract infections. Comp Ther Med 1997;5:40–42.
4. Hoheizel O, Sandberg M, Bertram S, et al. Echinacea shortens the course of the common cold: a double-blind, placebo-controlled clinical trial. Eur J Clin Res 1997;9:261–68.
5. Melchort D, Walther E, Linde K, et al. Echinacea root extracts for the prevention of upper respiratory tract infections: A double-blind, placebo-controlled randomized trial. Arch Fam Med 1998;7:541–45.
6. Brown DJ. Herbal Prescriptions for Better Health. Rocklin, CA: Prima Publishing, 1996, 63–68.
7. Blumenthal M, Busse WR, Goldberg A, et al, eds. The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 121–123.

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Gingko Biloba Supportive Information

The two known active components of the Ginkgo Biloba Extract are ginkgo flavone glycosides and the terpene lactones. These compounds have demonstrated anti-oxidant activity, enhanced circulatory activity and ability to decrease platelet "stickiness". These properties allow for improved blood flow to the brain (and other body organs and peripheral tissues) while enhancing central nervous tissue (brain) protection from free radical damage that may occur with aging. These findings make Ginkgo Biloba an important herb for brain and blood vessel protection and health.

Research Findings:

Numerous studies have addressed supplementation with Ginkgo biloba and the area of brain function. All of these studies revealed positive benefits of enhanced memory and cognitive function in both Alzheimer’s dementia and senile dementia (loss of memory in the elderly) in those individuals utilizing Ginkgo biloba extract. This is based on Ginkgo’s ability to reduce free radical damage to brain cells and its ability to enhance blood flow to the brain.

One study has suggested that elderly individuals with depression may respond to Ginkgo biloba with improvement in depression. Again, this was felt to be due to improvement in brain blood flow and "awakening" of the brain in these elderly individuals.

Tinnitus or ringing in the ears has also responded to Ginkgo biloba use. One double blind study has confirmed this. This is important research as no conventional treatments are available for this problem. Ginkgo generally requires a minimum of four to six months for benefit in tinnitus.

Also, there has been research demonstrating that males with impotence related to poor blood flow to the penis, received benefit from the use of this herb following six months of daily use. Fifty percent of the individuals with previous impotence were able to generate an erection following long-term use of this herb.

Side Effects:

This herb is well tolerated by most individuals although headache and gastrointestinal upset has been reported in a small percentage of users. Due to its ability to inhibit platelet function, individuals on blood thinning medication or other medication which affects platelet function should consult with their doctor prior to use.

References:

1. Kanowski S, Herrmann W, Stephan K, et al. Proof of efficacy of the Ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia. Pharmacopsychiatry 1996;29:47–56.
2. Ferrandini C, Droy-Lefaix MT, Christen Y, eds. Ginkgo biloba Extract (EGb 761) as a Free Radical Scavenger. Paris: Elsevier, 1993.
3. Lebuisson DA, Leroy L, Rigal G. Treatment of senile macular degeneration with Ginkgo biloba extract. A preliminary double-blind, drug versus placebo study. Presse Med 1986;15:1556–58 [in French].
4. Schubert H, Halama P. Depressive episode primarily unresponsive to therapy in elderly patients: Efficacy of Ginkgo biloba extract (EGb 761) in combination with antidepressants. Geriatr Forsch 1993;3:45–53.
5. Lamant V, Mauco G, et al. Inhibition of the metabolism of platelet activating factor (PAF-acether) by three specific antagonists from Ginkgo biloba. Biochem Pharmacol 1987;36:2749–52.
6. Krieglstein J. Neuroprotective properties of Ginkgo biloba—constituents. Zeitschrift Phytother 1994;15:92–96.
7. Haguenauer JP, Cantenot F, Koskas H, Pierart H. Treatment of equilibrium problems with extract of Ginkgo biloba. Multicenter, double-blind, placebo-controlled study. Presse Med 1986;15:1569–72 [in French].
8. Meyer B. A multicenter, double-blind, drug versus placebo study of Ginkgo biloba extract in the treatment of tinnitus. Press Med 1986;15:1562–64 [in French].
9. Blumenthal M, Busse WR, Goldberg A, et al, eds. The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 136–38.
10. Itil TM, Eralp E, Tsambis E, et al. Central nervous system effects of Ginkgo biloba, a plant extract. Am J Therapeutics 1996;3:63–73.
11. Le Bars PL, Katz MM, Berman N, et al. A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group. JAMA 1997;278:1327–32.
12. Hofferberth B. The efficacy of EGb 761 in patients with senile dementia of the Alzheimer type, a double-blind, placebo-controlled study on different levels of investigation. Human Psychopharmacol 1994;9:215–22.

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Golden Seal Root Supportive Information

The two primary phytochemicals in goldenseal are hydrastine and berberine. Little actual research has been done on the goldenseal root itself. Berberine, though, has undergone significant scientific evaluation. Berberine, which constitutes from 0.5% to 6% of the alkaloids present in goldenseal, appears to have antibiotic activity against a number of bacterial pathogens including, E.coli, Salmonella typhi, and Entamoeba histolytica. Research has shown berberine effective in the treatment of diarrhea and gastroenteritis.

Side Effects:

There are no significant side effects if used in recommended amounts, although a mild laxative as well as hypertensive effect are possible. If used over an extended period of time, it may cause digestive disorders, excitatory states, hallucinations and occasionally delirium.

Note - Goldenseal is NOT a substitute for antibiotics prescribed by your physician!

References:

1. Bhakat MP, Naudi N, et al. Therapeutic trial of berberine sulfate in non-specific gastroenteritis. Ind Med J 1974;68:19–23.
2. Bannerman JE. Goldenseal in world trade: Pressures and potenials. HerbalGram 1997;41:51–52.
3. Ellingwood F. American Materia Medica, Therapeutics and Pharmacognosy. 1919. Reprint, Sandy, OR: Eclectic Medical Publications, 1998.
4. Hahn FE, Ciak J. Berberine. Antibiotics 1976;3:577–88.
5. Werback M. Botanical Influences on Illness, 1994.

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Kava Kava Supportive Information

Kava-Kava - This herb, grown in the Pacific islands, is believed to directly affect the limbic system of the brain, the part of the brain associated with emotions. There are a number of excellent studies, which document the effectiveness of kava for people suffering from anxiety. Additionally, women undergoing uneasiness associated with menopause have also been shown to benefit from kava. Unlike prescription anti-anxiety medication, kava has no addictive properties.

When the following herbs are added as adjunctive herbal medicine to Kava Kava, the effectiveness of Kava Kava is enhanced.

Passion Flower - Physicians in Europe recommend passion flower for anti-anxiety treatment, particularly in situations of mental overwork, stress and nervousness. Passion flower has not been demonstrated to have any negative reactions when combined with other sedating agents.

Schizandra - This Chinese herb enjoys wide use in the Far East for numerous medical issues. One of its roles has been to assist in enhancing individuals’ response to stress not unlike ginseng.

Chamomile - Chamomile’s principle ingredients are flavonoids and essential oils. This herb has anti-inflammatory properties and anti-spasmodic properties within the bowel. Its inclusion is based on the ability of promoting a "relaxed stomach" during periods of stress.

Hops flower - Hops has also demonstrated mild sedative properties as well as enhancing digestive wellness. Its inclusion is primarily for promoting gastrointestinal relaxation during times of uneasiness or agitation.

Side Effects:

While rare, allergic reactions have been reported. Any such reaction should be reported to your health care professional and the herbs should be discontinued until advised by your health care professional.

Exceedingly strong doses of Kava Kava could result in the inability of the striated muscles, (your voluntary muscles needed for standing and walking etc.), to maintain posture. I witnessed one student of herbal medicine take an entire one ounce bottle of Kava Kava tincture as it was passed around the room for students to look at during an herbal seminar on Kava Kava. That particular student collapsed to the floor and could not move. He was completely consciousness, and all vital functions to maintain health remained intact. (Kava Kava did not affect the smooth muscles, or involuntary muscles of that student, the muscles of the heart, lungs, etc.) He just could not get up off the floor for several hours.

Kava Kava should NOT be taken together with other substances that also act on the central nervous system, such as alcohol, barbiturates, anti-anxiety sleep medications, antidepressants, and anti-psychotic drugs.

References:

1. Weiss RF. Herbal Medicine. Gothenburg, Sweden: Ab Arcanum, 1988, 285–86.
2. Blumenthal M, Busse WR, Goldberg A, et al, eds. The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 147.
3. Foster S. Herbs for Your Health. Loveland, CO: Interweave Press, 1996, 56–57. 6. Blumenthal M, Busse WR, Goldberg A, et al, eds. The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 107.
4. Meier B. Passiflora incarnata L.—Passion flower: Portrait of a medicinal plant. Zeitschrift Phytother 1995;16:115–26.
5.. Blumenthal M, Busse WR, Goldberg A, et al, eds. The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 156–57.
6. Blumenthal M, Busse WR, Goldberg A, et al, eds. The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 156–57.
7. Bone K. Kava: A safe herbal treatment for anxiety. Br J Phytother 1994;3:145–53.
8. Lehmann EE, Kinzler J, Friedmann J. Efficacy of a special kava extract (Piper methysticum) in patients with states of anxiety, tension and excitedness of non-mental origin. A double-blind placebo-controlled study of four weeks treatment. Phytomedicine 1996;3:113–19.
9. Volz HP, Kieser M. Kava-kava extract WS 1490 versus placebo in anxiety disorders. A randomized placebo-controlled 25-week outpatient trial. Pharmacopsychiatry 1997;30:1–5.

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Garlic Supportive Information

The active constituent of garlic is the sulfur compound allicin. The compound alliin is converted to allicin by the enzyme alliinase, which is activated when garlic is crushed.

A variety of commercial preparations exist on the market. For best results, powdered products standardized for alliin content are preferred. The dosage should provide a daily dose of 8 mg. alliin or a total allicin potential of 4000 mcg.

Pasteur noted garlic’s antibiotic activity in 1858 and Albert Schwietzer in Africa used garlic for the treatment of dysentery. More recent research has shown garlic to have broad-spectrum antimicrobial activity against many types of bacteria, viruses, worms, and fungi. Garlic is especially active against Candida Albicans. In addition to its antibiotic activity, garlic also has been shown to enhance various aspects of immune function. These effects support the historical use of garlic for a wide array of infectious conditions.

Garlic, though, is best known for its cardiovascular actions. Clinical studies have shown garlic to positively impact many key factors involved in heart and blood vessel disease. Garlic has been shown to lower blood pressure; lower LDL-cholesterol (bad cholesterol) in some studies, lower triglycerides (fats) and decrease blood stickiness (platelet aggregation).

Side Effects:

Garlic is generally safe and well tolerated although occasional individuals experience gastric upset or allergic dermatitis. As garlic may inhibit platelet function, individuals undergoing surgery should discontinue garlic at the advice of their health care professional prior to surgery.

References:

1. Hughes BG, Lawson LD. Antimicrobial effects of Allium sativum L. (garlic), Allium ampeloprasum L. (elephant garlic) and Allium cepa L. (onion), garlic compounds and commercial garlic supplement products. Phytother Res 1991;5:154–58.
2. Brown DJ. Herbal Prescriptions for Better Health. Rocklin, CA: Prima Publishing, 1996, 97–109.
3. Blumenthal M, Busse WR, Goldberg A, et al, eds. The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 134.
4. Brown DJ. Herbal Prescriptions for Better Health. Rocklin, CA: Prima Publishing, 1996, 97–109.
5. Silagy C, Neil A. A meta-analysis of the effect of garlic on blood pressure. J Hyperten 1994;12(4):463–68.
6. Kleijnen J, Knipschild P, Ter Riet G. Garlic, onion and cardiovascular risk factors: A review of the evidence from human experiments with emphasis on commercially available preparations. Br J Clin Pharmacol 1989;28:535–44.
7. Warshafsky S, Kamer R, Sivak S. Effect of garlic on total serum cholesterol: A meta-analysis. Ann Int Med 1993;119(7)599–605.
8. Silagy C, Neil A. Garlic as a lipid-lowering agent—a meta-analysis. J R Coll Phys London 1994;28(1):39–45.
9. Neil HAW, Silagy CA, Lancaster T, et al. Garlic powder in the treatment of moderate hyperlipidaemia: A controlled trial and a meta-analysis. J R Coll Phys 1996;30:329–34.
10. Isaacsohn JL, Moser M, Stein EA, et al. Garlic powder and plasma lipids and lipoproteins. Arch Intern Med 1998;158:1189–94.
11. Kleijnen J, Knipschild P, Ter Riet G. Garlic, onion and cardiovascular risk factors: A review of the evidence from human experiments with emphasis on commercially available preparations. Br J Clin Pharmacol 1989;28:535–44.

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Valerian Supportive Information

Valerian may bind to the GABA receptors in the brain. These are the “relaxation” receptors within the central nervous system. This would explain its benefits in stress and anxiety reduction.

Double blind studies have shown that valerian is more effective than placebo for people with sleep difficulties. Valerian appears to allow sleep onset to occur more quickly, provides more restful sleep but does not increase total sleep time.

Side Effects:

Valerian has no significant side effects. It does not lead to addiction or dependence.

References:

1. Mennini T, Bernasconi P, et al. In vitro study on the interaction of extracts and pure compounds from Valeriana officinalis roots with GABA, benzodiazepine and barbiturate receptors. Fitoterapia 1993;64:291–300.
2. Kohnen R, Oswald WD. The effects of valerian, propranolol and their combination on activation performance and mood of healthy volunteers under social stress conditions. Pharmacopsychiatry 1988;21:447–48.
3. Leathwood PD, Chauffard F, Heck E, Munoz-Box R. Aqueous extract of valerian root (Valeriana officinalis L) improves sleep quality in man. Pharmacol Biochem Behav 1982;17:65–71.
4. Leathwood PD, Chauffard F. Aqueous extract of valerian reduces latency to fall asleep in man. Planta Med 1985;51:144–48.
5. Lindahl O, Lindwall L. Double-blind study of a valerian preparation. Pharmacol Biochem Behav 1989;32:1065–66.
6. Brown DJ. Herbal Prescriptions for Better Health. Rocklin, CA: Prima Publishing, 1996, 173–78.

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DISCLAIMER This information is provided for Educational Purposes Only and has NOT been designed to diagnose, treat or cure any health conditions. Please consult a qualified Health Care Professional with Nutritional Training to diagnose your health conditions and avoid self-diagnosis. The U.S. Food and Drug Administration have not evaluated statements about these health topics or any suggested product compositions.