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Gene Testing

 

Medical researchers are now able to look within cells, and are making new discoveries that explain how genes are related to cancer and other diseases. They have identified specific genes linked to breast cancer and other cancers that run in families. Tests are becoming available for women and family members who choose to find out if they have inherited the genetic changes that increase their risk for cancer. There is still much uncertainty involved with gene testing. If you or your family members are considering testing, your doctor or a genetics counselor can give you guidance and help you make an informed decision. It's important to consider carefully the benefits, risks, limitations, and the far-reaching consequences of gene testing.

The only way to find out for sure if a breast lump or abnormal tissue is cancer is by having a biopsy. The suspicious tissue that is removed by a surgeon or radiologist during a biopsy is examined under a microscope by a pathologist who makes the diagnosis. If your biopsy result is positive, it means that the tumor or tissue from the suspicious area contains cancer and you will need treatment. Information on the following pages can help you understand the various treatments that are available and decide what is best for you. It is safe to begin treatment up to several weeks after diagnosis.

 


What Causes Breast Cancer?

Medical researchers are learning about what happens inside cells that may cause cancer. They have identified changes in certain genes within breast cells that can be linked to a higher risk for breast cancer. Breast cells contain a variety of genes that normally work cooperatively with a woman's natural hormones, diet, and environment to keep her breasts healthy. Certain genes routinely keep breast cells from dividing and growing out of control and forming tumors. When these genes become altered, changes occur and a cell no longer can grow correctly.

Genetic changes may be inherited from a parent or may accumulate throughout a person's lifetime. Breast cancer usually begins in a single cell that changes from normal to malignant over a period of time. Presently, no one can predict exactly when cancer will occur or how it will progress. When breast cancer is diagnosed - even if detected at the earliest stage - it is not yet possible to predict which cancer cells will be treated successfully and which will continue to grow and spread quickly to other parts of the body.

What is known:

  • You should not feel guilty. You haven't done anything wrong in your life that caused breast cancer.

  • You cannot "catch" breast cancer from other women who have the disease. It is not contagious.

  • Breast cancer is not caused by stress or by an injury to the breast.

Most women who develop breast cancer do not have any known risk factors or a history of the disease in their families.

 

 


Are They Breast Cancers Alike?

Once breast cancer has been found, more tests will Breast cancer is a complex disease. All cases are not the same be done to find out the specific pattern (description) of your disease. This important step is called staging. The following chart explains the stages. Knowing the exact stage of your disease will help your doctor plan your treatment. Your doctor will want to know:

  • The size of the tumor and exactly where it is in your breast.
  • If the cancer has spread within your breast.
  • If cancer is present in your lymph nodes under your arm.
  • If cancer is present in other parts of your body.
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